SlideShare a Scribd company logo
About US:
Manzo Pharmaceuticals LLC. is a startup specialty
pharmaceutical company that is developing a range of innovative
and affordable formulations for various drugs and
supplement. We are focused on addressing the unmet medical
needs of patients with innovative, patient-friendly and
affordable solutions. We are currently doing research on helping
people with lactose intolerance.
http://manzopharma.com/
Ken Manzo, R.Ph., Founder of Manzo Pharmaceuticals
LLC, Graduated St. John’s University with a degree in
Pharmaceutical Science. He is the inventor of the
patented Lacto-Freedom™ probiotic and is working
closely with Celprogen, Inc. to produce, develop, and test
the safety and efficacy of the product. See More at
http://manzopharma.com/
Lacto-Freedom™ Probiotic
A new and unique patented probiotic that aids in the digestion of lactose containing
foods, designed specifically for people with lactose intolerance. After being taken for
only 24 hours, this probiotic stays in the intestines and produces lactase for at least 3
months. More recent tests showed that the probiotic stayed in the intestines and
produced lactase in lab rats for a full 6 months after taking the probiotic for only 7
days. In addition, there were no side effects observed throughout the entire study.
Lactose intolerance is the inability to digest lactose, a sugar found in milk and milk products. Lactose
intolerance is caused by a deficiency of lactase, the enzyme which is produced by the cells lining the
small intestine. Lactase breaks down lactose into two simpler forms of sugar which are then absorbed
into the bloodstream. Common foods that are high in lactose include dairy products such as milk,
cheese, and ice cream. Lactose is also added to some foods, such as bread and baked goods, cereals,
salad dressings, candies, and snacks. Patients with lactose intolerance often experience abdominal
pain, gas, bloating, diarrhea, and nausea after consuming lactose containing foods. Symptoms range
from mild to severe, based on the amount of lactose consumed and the amount a person can tolerate.
Experts believe lactose intolerance affects up to 75% of the world’s adult population.
Currently, patients with lactose intolerance are limited to two mediocre options for managing their
lactose intolerance. Their limited options include avoiding lactose-containing foods and the other is
taking lactase supplements at the start of every single lactose containing meal. View More at
http://manzopharma.com/lacto-relief-for-people-with-la-ctose-intolerance/
With Lacto-Freedom™ probiotic, patients may enjoy dairy products and
lactose containing products without experiencing abdominal pain, gas,
abdominal bloating, diarrhea, and nausea…and without the hassle of taking
lactase supplements with every lactose containing meal. The patient would
take this probiotic for a short amount of time (24 hours) and the effects last
for 3 months or more.
We are developing a better option…
The intestinal lining is made up of billions of bacteria, both good and
bad. Probiotics are supplements which contain “good” bacteria and when
consumed add beneficial bacteria to the intestines. We developed a probiotic
that produces lactase and stays in the intestines for at least three months. See
More at http://manzopharma.com/
Lactose intolerance is a common condition that is more likely to occur in
adulthood, with a higher incidence in older adults. Some ethnic and racial
populations are more affected than others, including African Americans,
Hispanic Americans, American Indians, and Asian Americans. The condition is
least common among Americans of northern European descent.
Infants born prematurely are more likely to have lactase deficiency because an
infant’s lactase levels do not increase until the third trimester of pregnancy.
The cause of lactose intolerance is best explained by describing how a person develops lactase
deficiency.
Primary lactase deficiency develops over time and begins after about age 2 when the body begins to
produce less lactase. Most children who have lactase deficiency do not experience symptoms of
lactose intolerance until late adolescence or adulthood.
Researchers have identified a possible genetic link to primary lactase deficiency. Some people inherit a
gene from their parents that makes it likely they will develop primary lactase deficiency. This discovery
may be useful in developing future genetic tests to identify people at risk for lactose intolerance.
Secondary lactase deficiency results from injury to the small intestine that occurs with severe diarrheal
illness, celiac disease, Crohn’s disease, or chemotherapy. This type of lactase deficiency can occur at
any age but is more common in infancy.
People with lactose intolerance may feel uncomfortable 30 minutes to 2 hours after
consuming milk and milk products. Symptoms range from mild to severe, based on the
amount of lactose consumed and the amount a person can tolerate.
Common symptoms include
• Abdominal Pain
• Abdominal Bloating
• Gas
• Diarrhea
• Nausea
http://manzopharma.com/
http://manzopharma.com/
Milk and milk products are often added to processed foods—
foods that have been altered to prolong their shelf life. People
with lactose intolerance should be aware of the many food
products that may contain even small amounts of lactose, such
as
bread and other baked goods
waffles, pancakes, biscuits, cookies, and mixes to make them
processed breakfast foods such as doughnuts, frozen waffles
and pancakes, toaster pastries, and sweet rolls
processed breakfast cereals
instant potatoes, soups, and breakfast drinks
potato chips, corn chips, and other processed snacks
processed meats, such as bacon, sausage, hot dogs, and lunch
meats
margarine
salad dressings
liquid and powdered milk-based meal replacements
protein powders and bars
candies
Lactose intolerance can be hard to diagnose based on symptoms alone. People may think they suffer from
lactose intolerance because they have digestive symptoms; however, other conditions such as irritable
bowel syndrome can cause similar symptoms. After taking a medical history and performing a physical
examination, the doctor may first recommend eliminating all milk and milk products from the person’s
diet for a short time to see if the symptoms resolve. Tests may be necessary to provide more information.
Two tests are commonly used to measure the digestion of lactose.
Hydrogen Breath Test. The person drinks a lactose-loaded beverage and then the breath is analyzed at
regular intervals to measure the amount of hydrogen. Normally, very little hydrogen is detectable in the
breath, but undigested lactose produces high levels of hydrogen. Smoking and some foods and
medications may affect the accuracy of the results. People should check with their doctor about foods and
medications that may interfere with test results.
Stool Acidity Test. The stool acidity test is used for infants and young children to measure the amount of
acid in the stool. Undigested lactose creates lactic acid and other fatty acids that can be detected in a
stool sample. Glucose may also be present in the stool as a result of undigested lactose.
Because lactose intolerance is uncommon in infants and children younger than 2, a health professional
should take special care in determining the cause of a child’s digestive symptoms.
http://manzopharma.com/
http://manzopharma.com/
http://manzopharma.com
Lacto-Freedom Probiotic
Lacto-Freedom Probiotic
Lacto-Freedom Probiotic

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Lacto-Freedom Probiotic

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  • 2. About US: Manzo Pharmaceuticals LLC. is a startup specialty pharmaceutical company that is developing a range of innovative and affordable formulations for various drugs and supplement. We are focused on addressing the unmet medical needs of patients with innovative, patient-friendly and affordable solutions. We are currently doing research on helping people with lactose intolerance. http://manzopharma.com/
  • 3. Ken Manzo, R.Ph., Founder of Manzo Pharmaceuticals LLC, Graduated St. John’s University with a degree in Pharmaceutical Science. He is the inventor of the patented Lacto-Freedom™ probiotic and is working closely with Celprogen, Inc. to produce, develop, and test the safety and efficacy of the product. See More at http://manzopharma.com/
  • 4. Lacto-Freedom™ Probiotic A new and unique patented probiotic that aids in the digestion of lactose containing foods, designed specifically for people with lactose intolerance. After being taken for only 24 hours, this probiotic stays in the intestines and produces lactase for at least 3 months. More recent tests showed that the probiotic stayed in the intestines and produced lactase in lab rats for a full 6 months after taking the probiotic for only 7 days. In addition, there were no side effects observed throughout the entire study.
  • 5. Lactose intolerance is the inability to digest lactose, a sugar found in milk and milk products. Lactose intolerance is caused by a deficiency of lactase, the enzyme which is produced by the cells lining the small intestine. Lactase breaks down lactose into two simpler forms of sugar which are then absorbed into the bloodstream. Common foods that are high in lactose include dairy products such as milk, cheese, and ice cream. Lactose is also added to some foods, such as bread and baked goods, cereals, salad dressings, candies, and snacks. Patients with lactose intolerance often experience abdominal pain, gas, bloating, diarrhea, and nausea after consuming lactose containing foods. Symptoms range from mild to severe, based on the amount of lactose consumed and the amount a person can tolerate. Experts believe lactose intolerance affects up to 75% of the world’s adult population.
  • 6. Currently, patients with lactose intolerance are limited to two mediocre options for managing their lactose intolerance. Their limited options include avoiding lactose-containing foods and the other is taking lactase supplements at the start of every single lactose containing meal. View More at http://manzopharma.com/lacto-relief-for-people-with-la-ctose-intolerance/
  • 7. With Lacto-Freedom™ probiotic, patients may enjoy dairy products and lactose containing products without experiencing abdominal pain, gas, abdominal bloating, diarrhea, and nausea…and without the hassle of taking lactase supplements with every lactose containing meal. The patient would take this probiotic for a short amount of time (24 hours) and the effects last for 3 months or more. We are developing a better option…
  • 8. The intestinal lining is made up of billions of bacteria, both good and bad. Probiotics are supplements which contain “good” bacteria and when consumed add beneficial bacteria to the intestines. We developed a probiotic that produces lactase and stays in the intestines for at least three months. See More at http://manzopharma.com/
  • 9. Lactose intolerance is a common condition that is more likely to occur in adulthood, with a higher incidence in older adults. Some ethnic and racial populations are more affected than others, including African Americans, Hispanic Americans, American Indians, and Asian Americans. The condition is least common among Americans of northern European descent. Infants born prematurely are more likely to have lactase deficiency because an infant’s lactase levels do not increase until the third trimester of pregnancy.
  • 10. The cause of lactose intolerance is best explained by describing how a person develops lactase deficiency. Primary lactase deficiency develops over time and begins after about age 2 when the body begins to produce less lactase. Most children who have lactase deficiency do not experience symptoms of lactose intolerance until late adolescence or adulthood. Researchers have identified a possible genetic link to primary lactase deficiency. Some people inherit a gene from their parents that makes it likely they will develop primary lactase deficiency. This discovery may be useful in developing future genetic tests to identify people at risk for lactose intolerance. Secondary lactase deficiency results from injury to the small intestine that occurs with severe diarrheal illness, celiac disease, Crohn’s disease, or chemotherapy. This type of lactase deficiency can occur at any age but is more common in infancy.
  • 11. People with lactose intolerance may feel uncomfortable 30 minutes to 2 hours after consuming milk and milk products. Symptoms range from mild to severe, based on the amount of lactose consumed and the amount a person can tolerate. Common symptoms include • Abdominal Pain • Abdominal Bloating • Gas • Diarrhea • Nausea
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  • 19. Milk and milk products are often added to processed foods— foods that have been altered to prolong their shelf life. People with lactose intolerance should be aware of the many food products that may contain even small amounts of lactose, such as bread and other baked goods waffles, pancakes, biscuits, cookies, and mixes to make them processed breakfast foods such as doughnuts, frozen waffles and pancakes, toaster pastries, and sweet rolls processed breakfast cereals instant potatoes, soups, and breakfast drinks potato chips, corn chips, and other processed snacks processed meats, such as bacon, sausage, hot dogs, and lunch meats margarine salad dressings liquid and powdered milk-based meal replacements protein powders and bars candies
  • 20. Lactose intolerance can be hard to diagnose based on symptoms alone. People may think they suffer from lactose intolerance because they have digestive symptoms; however, other conditions such as irritable bowel syndrome can cause similar symptoms. After taking a medical history and performing a physical examination, the doctor may first recommend eliminating all milk and milk products from the person’s diet for a short time to see if the symptoms resolve. Tests may be necessary to provide more information. Two tests are commonly used to measure the digestion of lactose. Hydrogen Breath Test. The person drinks a lactose-loaded beverage and then the breath is analyzed at regular intervals to measure the amount of hydrogen. Normally, very little hydrogen is detectable in the breath, but undigested lactose produces high levels of hydrogen. Smoking and some foods and medications may affect the accuracy of the results. People should check with their doctor about foods and medications that may interfere with test results. Stool Acidity Test. The stool acidity test is used for infants and young children to measure the amount of acid in the stool. Undigested lactose creates lactic acid and other fatty acids that can be detected in a stool sample. Glucose may also be present in the stool as a result of undigested lactose. Because lactose intolerance is uncommon in infants and children younger than 2, a health professional should take special care in determining the cause of a child’s digestive symptoms.