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By: Jehad abdullah
What is the difference between this milk and
ordinary milk?
What is Lactose Intolerance?
 Inability to digest
significant amounts
of lactose, result of
lactase insufficiency.
 Symptoms caused by
maldigestion of
lactose
Milk digestion
 The cells lining the
small intestine
produce an enzyme
called lactase
 Lactase enzyme
breaks down
lactose into two
simpler sugars
called glucose and
galactose.
Lactose in the intestine
80 % of adults worldwide do not produce
lactase
 Males and females are equally
 During pregnancy, 44% regain the ability to
digest lactose. This is probably due to slow
intestinal transit.
 Age
 Among adults, the age of presentation of
lactose intolerance is 20-40 years
Babies are lactose tolerant
Lactose Intolerance
vs Milk Allergy
Lactose intolerance Milk allergy
A sensitivity An allergy
Occurs in gastrointestinal system Triggered by immune system
A sensitivity to milk carbohydrate
(lactose)
A reaction to milk protein
Rare in young children
Generally impacts young
children; may be outgrown*
Can enjoy milk and milk products
with simple management
strategies
Should avoid milk
and milk products
(unless allergy is outgrown)
Types of Lactase Deficiency
 Primary lactase deficiency (most common)
- lactase production declines over time
- begins at about age 2
- Researchers have discovered that some
people inherit genes from their parents
Cont’
 Secondary lactase deficiency
results from:-
- injury to the small intestine.
- Infection
- diseases
Cont’
 Developmental lactase deficiency
- in infants born prematurely
- This condition usually lasts for only a short time
after they are born.
 Congenital lactase deficiency
- rare disorder in which the small intestine produces
little or no lactase enzyme from birth. Genes
inherited from parents cause this disorder.
Cont’
 Familial lactase deficiency
- lactase production is fine, but it does not do
the job. It does not break down the lactase
into glucose and galactose so that it can be
absorbed into the bloodstream. This condition
is also inherited from the parents.
bloated feeling,
Stomach cramps
diarrhoea
flatulence nausea,
vomitting
excessive gas in the intestinal tract
an hour or two after consuming lactose
risk factors of lactose intolerance
 Age
 Ancestry
 Radiotherapy
 Being born prematurely
lactose intolerance diagnosed
 Medical, family, and diet history. A
health care provider will take a
medical, family, and diet history to
help diagnose lactose intolerance.
 Physical exam
- checks for abdominal bloating
- uses a stethoscope to listen to
sounds within the abdomen
- taps on the abdomen to check for
tenderness or pain
lactose intolerance diagnosed
 Medical tests
- Hydrogen breath test
- Lactose tolerance test
lactose intolerance diagnosed
 Stool acidity
test
- Undigested lactose
creates lactic acid and
other fatty acids that a
stool acidity test can
detect in a stool sample.
Health care providers
sometimes use this test
to check acidity in the
stools of infants and
young children.
management
 Lactose-free and lactose-reduced milk and
milk products
 Alternatives to Soy Milk
How much lactose can a person with
lactose intolerance have?
 Most people with lactose intolerance can
tolerate some amount of lactose in their
diet and do not need to avoid milk or milk
products completely. Avoiding milk and
milk products altogether may cause
people to take in less calcium and vitamin
D than they need. See the “Calcium and
Vitamin D” section
 Research suggests that adults and
adolescents with lactose malabsorption
could eat or drink at least 12 grams of
lactose in one sitting without symptoms
or with only minor symptoms. This
amount is the amount of lactose in 1 cup
of milk
 Lactase products
- People can use lactase tablets and drops when they eat or drink milk
products.
References
 http://digestive.niddk.nih.gov/DDISEASES/p
ubs/lactoseintolerance/
 http://www.betterhealth.vic.gov.au/bhcv2/b
hcarticles.nsf/pages/Lactose_intolerance
 Ganong's of Medical Physiology, 23rd Edition
 Rubin’s basic pathology , ninth Edition

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Latose intilerance

  • 2. What is the difference between this milk and ordinary milk?
  • 3. What is Lactose Intolerance?  Inability to digest significant amounts of lactose, result of lactase insufficiency.  Symptoms caused by maldigestion of lactose
  • 4. Milk digestion  The cells lining the small intestine produce an enzyme called lactase  Lactase enzyme breaks down lactose into two simpler sugars called glucose and galactose.
  • 5. Lactose in the intestine
  • 6. 80 % of adults worldwide do not produce lactase
  • 7.  Males and females are equally  During pregnancy, 44% regain the ability to digest lactose. This is probably due to slow intestinal transit.  Age  Among adults, the age of presentation of lactose intolerance is 20-40 years
  • 9. Lactose Intolerance vs Milk Allergy Lactose intolerance Milk allergy A sensitivity An allergy Occurs in gastrointestinal system Triggered by immune system A sensitivity to milk carbohydrate (lactose) A reaction to milk protein Rare in young children Generally impacts young children; may be outgrown* Can enjoy milk and milk products with simple management strategies Should avoid milk and milk products (unless allergy is outgrown)
  • 10. Types of Lactase Deficiency  Primary lactase deficiency (most common) - lactase production declines over time - begins at about age 2 - Researchers have discovered that some people inherit genes from their parents
  • 11. Cont’  Secondary lactase deficiency results from:- - injury to the small intestine. - Infection - diseases
  • 12. Cont’  Developmental lactase deficiency - in infants born prematurely - This condition usually lasts for only a short time after they are born.  Congenital lactase deficiency - rare disorder in which the small intestine produces little or no lactase enzyme from birth. Genes inherited from parents cause this disorder.
  • 13. Cont’  Familial lactase deficiency - lactase production is fine, but it does not do the job. It does not break down the lactase into glucose and galactose so that it can be absorbed into the bloodstream. This condition is also inherited from the parents.
  • 14. bloated feeling, Stomach cramps diarrhoea flatulence nausea, vomitting excessive gas in the intestinal tract an hour or two after consuming lactose
  • 15. risk factors of lactose intolerance  Age  Ancestry  Radiotherapy  Being born prematurely
  • 16. lactose intolerance diagnosed  Medical, family, and diet history. A health care provider will take a medical, family, and diet history to help diagnose lactose intolerance.  Physical exam - checks for abdominal bloating - uses a stethoscope to listen to sounds within the abdomen - taps on the abdomen to check for tenderness or pain
  • 17. lactose intolerance diagnosed  Medical tests - Hydrogen breath test - Lactose tolerance test
  • 18. lactose intolerance diagnosed  Stool acidity test - Undigested lactose creates lactic acid and other fatty acids that a stool acidity test can detect in a stool sample. Health care providers sometimes use this test to check acidity in the stools of infants and young children.
  • 19. management  Lactose-free and lactose-reduced milk and milk products  Alternatives to Soy Milk
  • 20. How much lactose can a person with lactose intolerance have?  Most people with lactose intolerance can tolerate some amount of lactose in their diet and do not need to avoid milk or milk products completely. Avoiding milk and milk products altogether may cause people to take in less calcium and vitamin D than they need. See the “Calcium and Vitamin D” section  Research suggests that adults and adolescents with lactose malabsorption could eat or drink at least 12 grams of lactose in one sitting without symptoms or with only minor symptoms. This amount is the amount of lactose in 1 cup of milk
  • 21.  Lactase products - People can use lactase tablets and drops when they eat or drink milk products.