Keratoconus is a non-inflammatory thinning of the cornea that causes it to assume a conical shape, impairing vision. It is usually bilateral and centered below the visual axis. Other similar conditions include pellucid marginal degeneration, keratoglobus, and post-keratoconus. Keratoconus is associated with genetic disorders and eye diseases and can be diagnosed using signs like Munson's sign, Rizzuti's sign, and scissoring on retinoscopy. As it progresses, the cornea develops thinning, Fleischer's ring, Vogt's striae, and scarring. In severe cases, the cornea can rupture causing hydrops.
This presentation describes all the clinical aspects of keratoconus management
You can watch the illustrated presentation in this link :
https://www.youtube.com/watch?v=pYxwZPGm7e4&list=PLZ_mM13I_TrhWavjTmE9NjW1O5bGxkONO&index=13
This presentation describes all the clinical aspects of keratoconus management
You can watch the illustrated presentation in this link :
https://www.youtube.com/watch?v=pYxwZPGm7e4&list=PLZ_mM13I_TrhWavjTmE9NjW1O5bGxkONO&index=13
Vitelliform dystrophy, or Best disease,
is a hereditary retinal dystrophy involving the retinal pigment epithelium (RPE), and leads to a characteristic bilateral yellow “egg-yolk” appearance of the macula
This is my presentation on Understanding Keratoconus, how the defect occur.
Each stage of Keratoconus with the treatment needed and latest technology on how to treat
My aim is to help people understand more about this eye defect to be more aware of it
Vitelliform dystrophy, or Best disease,
is a hereditary retinal dystrophy involving the retinal pigment epithelium (RPE), and leads to a characteristic bilateral yellow “egg-yolk” appearance of the macula
This is my presentation on Understanding Keratoconus, how the defect occur.
Each stage of Keratoconus with the treatment needed and latest technology on how to treat
My aim is to help people understand more about this eye defect to be more aware of it
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2. Keratoconus is a condition in which
cornea assumes a conical shape because of
thinning and protrusion. Cellular
infiltration and vascularization do not
occur. It is usually b/l and, although it
involves central two-thirds of cornea, apex
of cone is usually centered just below
visual axis. This results in mild to marked
impairment of visual function.
3. They are keratoconus,
, , and
.
first three disorders may actually represent variations
in phenotypic expression of same pathogenetic
mechanism.
Corneal thinning is a hallmark of these ectatic
diseases. area of maximal thinning, relative to
location of maximal corneal protrusion, is helpful
in differentiating these conditions.
4. • PMD is a b / l , non-inflammatory,
peripheral corneal thinning disorder
characterized by a peripheral band of
thinning of the inferior cornea. The cornea
in and adjacent to the thinned area is
ectatic.The etiology of PMD has not been
clearly established, but collagen
abnormalities, as seen in KC, have been
reported. Patients usually are aged 20–40
years at the time of clinical presentation
5.
6. • It is a generalized thinning of cornea .
thinning is marked at limbus,
extending circumferentially for 360°; this
makes it different from the globus
morphological pattern of the KC.• The
whole cornea protrudes, in contrast to
the regional thinning seen in KC and the
inferior paralimbal thinning in PMD.
7.
8. • Forme Fruste Keratoconus (FFKC) is a
subclinical disease and is not a variant of KC.
Although clinicians use many other terms
such as mild KC, early KC, and subclinical
KC, their exact meanings and applications
are less certain. These terms are not
universally accepted.
• The diagnosis of KC is a clinical one that is
aided by topography, while the diagnosis of
FFKC is topographic.
9. • FFKC is a completely normal cornea
with neither clinical nor topographical
risk factors, but this cornea is able to
develop KC when treated by laser.
• The fellow eye may be keratoconic or
there may be a family history of KC
10. • FFKC is an abnormal cornea. Corneal
topography or corneal hysteresis or
both are abnormal; i.e., there are risk
factors but the case is still not a
clinically obvious KC.
13. • KC occurs with increased frequency with
systemic and ocular conditions:
1. Systemic disorders:
• Down’s syndrome, Turner syndrome, Ehlers-
Dunlos syndrome, Marfan syndrome,atopy,
osteogenesis imperfecta, and mitral valve
prolapse.
2. Ocular associations:
• Vernal disease, retinitis pigmentosa, blue
sclera, aniridia, and ectopia lentis
14. • Munson’s sign : When the patient is asked to
look downward toward the floor, a V-shaped
profile of the lower lid margin can be seen .
Moderate-to severe KC tends to produce
Munson’s sign, while mild cases will not
produce this sign .
• Rizzuti’s sign : This sign is observed by
seeing a light on the nasal anterior sclera
when the light is directed into the cornea
from the temporal direction
15.
16. • scissoring effect of the retinal reflex
seen with retinoscopy is highly
diagnostic of KC (and of all forms of
irregular astigmatism). It is best seen
when the pupils are dilated. Unlike
Munson’s sign, scissoring effect is
considered to be sensitive to even mild
forms of KC
17.
18. • Focal thinning :
• focal thinning occurs at the cone apex,which
is usually located inferior to the center of
cornea; in pellucid marginal degeneration
(PMD), this focal thinning is located in the
lower third of the cornea.
• Fleischer’s ring :
• It is due to accumulation of ferritin particles
in corneal basal epithelial cells. It encircles
the base of the cone.
19. As cornea continues to thin and bulge
out,“stretch marks” may develop in form of
thin,bright lines located deep in the stroma
adjacent to Descemets’ membrane called
Vogt’s striae . Vogt’s striae are a sign of
corneal stretching
and protrusion. When cornea is depressed,
Vogt’s striae often disappear. These striae are
sometimes called stress lines.
20. • Anterior stromal scars may develop due to
continuous protrusion of the cornea.
These scars may be small or large .
• The size and location of the scars
determines its impact on visual function.
• If stretching becomes excessive, the
cornea may eventually tear in the
Descemets’ membrane leading
to fluid accumulation within the stroma
and therefore to hydrops cornea .
21. This intense stromal edema often results
in an acutely blurred vision since the
tears often occur centrally.
• When the endothelium migrates to
cover the tear,edema resolves and a
posterior scar may form.
• Tears can occur in corneal periphery
which may have minimal impact on
vision