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Requirement for this lecture:
      •one balloon that is easy to inflate and
          •one that is difficult to inflate
Respiratory Waveforms
 Nasal Flow via nasal cannula


 Oral/nasal flow via thermistor


 Effort via esophageal pressure (not often used)


 Rib cage and abdominal movement via RIP
 (respiratory inductive plethysmograph)
Rib cage and abdominal belts (RIP)
 During quiet, unobstructed breathing the belts move
 in and out together. This reflects the RC(rib cage) and
 Ab(abdomen) expanding and relaxing together.

 With partial obstruction the belts can begin to move
 out of phase with each other.
Rib cage and abdominal belts (RIP)
 With significant or full obstruction the belts will move
  in paradox; that is one moves out when the other
  moves in. This is because the airway is now a closed
  system-the volume doesn’t change. So, if you expand
  your chest (increasing chest volume) you have to
  decrease your abdominal volume and vice versa.
 Now fill your balloon with air (or water if you like) and
  tie it off. What happens to the top of the balloon if you
  squeeze the bottom? What happens to the bottom if
  you squeeze the top? That is PARADOX!
Thermistor
 This measures temperature change as air moves in an
  out.
 It can tell you the presence of air flow but cannot give
  you information about the quality of that flow such as
  flow limitation.
Nasal cannula
 Actually measures the pressure changes as air moves
    past the cannula.
   In a closed system like a nasal mask (with no leak)
    pressure equals flow.
   In a small area (like the inside of the nose) pressure is
    very similar to flow.
   This would not work for oral flow because it is not a
    closed area.
   The signal you see is showing the rate of change of the
    inspiratory and expiratory pressure
Unobstructed Airflow measured by
      mask or nasal canula
 Inspiratory flow




    Expiratory flow
                                   Zero flow

 Notice that the unobstructed inspiratory flow (pressure) signal is rounded.
 As the signal moves up it is showing the flow rate increasing and as the
 signal moves back to zero the rate of flow is decreasing.

 The expiratory signal is pointed and gradually returns to zero. Inspiratory
 flow should always be up.
Partially obstructed inspiratory
                 flow (UAR)
Notice the concave shape of the inspiratory
flow signal




    This occurs because during inspiration the
    airway narrows and the rate of inspiratory
    flow decreases despite increasing effort.
Compare the obstructed and
  unobstructed breaths
Esophageal Pressure (Pes)

 A balloon on a catheter is placed through the nose into
  the esophagus.
 This pressure reflects the pressure being generated in
  the larynx.
 When you breathe in the negative pressure changes
  the pressure in the balloon and it returns to normal
  during relaxed exhalation.
 The harder it is to breathe (increased resistance,
  snoring, upper airway obstruction) the more negative
  pressure you have to develop to draw in air.
Esophageal pressure (Pes)
Notice that Pes is negative during inspiratory flow. This indicates the negative
(suction) pressure generated by the expansion of the lungs that causes inspiratory
flow. Pressure returns to zero during relaxed expiration.
The next slide shows you how pressure and flow change from wake to sleep to
increased resistance/snoring.
Rounded
                                          Notice the rounded inspiratory
  Wake        inspiratory
              flow                        flow, little effort (Pes-esophageal
                 Little                   pressure indicates how hard you
                 effort                   work to pull in air), and RC and AB
                                          are in phase
                 RC and
                 AB in
                 phase




  Sleep-                                     The airway is still open although
  open                                      breathing frequency is higher
                                            than awake – rounded flow, little
  airway                                    effort, and RC and AB are still in
                                            phase




                                           Notice now the inspiratory flow
             Insp. Flow is collapsed
Sleep-       Indicating flow limitation    signal is not rounded but is
Flow                                       collapsed a little, Pes is bigger
              Greater pressure
                                           indicating much more pressure
limitation    Development means more
              work                         has to be developed to breath and
                RC and AB out of           RC and AB are paradoxing
                phase
Respiratory belts, airflow and respiratory effort (Pes) when
                 partial obstruction resolves

This picture shows an
individual moving from
partial obstruction to a
fully open airway.

Notice that when airflow
(measured by nasal pressure in the
first few breaths of channel “e”)
shows flow limitation –
the RC (a) and AB (b) are
in paradox. The pressure
developed (f) is large.

In the last breath, with no
flow limitation, the belts
are in phase and little
pressure is developed
Why does this happen?

Remember:
 The upper airway is composed partially of muscle.
 Upper airway muscles relax in sleep
 This allows the airway to narrow in everyone and in
  some to partially or fully collapse.

 The next slide shows the airway changing from wake to
 sleep to snoring to hypopnea to apnea. Below that are
 the effects on flow and pressure.
Sleep on the upper airway and its consequences
CPAP on the Upper airway
 CPAP’s positive airway pressure essentially takes the
  place of the relaxed muscles to hold open the airway.
  Get your easy to inflate balloon and blow just enough
  air in to stretch it a little. Now try it again with the
  stiffer balloon. Can you tell that it takes more pressure
  for you to inflate the second balloon?
 Peoples airways are like balloons with different degrees
  of stiffness. This is why they need different levels of
  PAP.
Bilevel Pressure on the Upper Airway
 Bilevel pressure is a combination of CPAP (which is
  the expiratory pressure) and mechanical ventilation
  which helps to inflate the lungs.
 Now blow enough air in one balloon just to hold it
  open (point A.) That is the CPAP.
 Now, holding that pressure inflate your balloon a little
  (point B) then let the pressure back to point A.
 This simulates what bilevel pressure does. It hold the
  airway pressure at a certain level to keep it open then
  adds more air pressure during inspiration to increase
  the size of the breath.

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Jsrcc airflow and cpap

  • 1. Requirement for this lecture: •one balloon that is easy to inflate and •one that is difficult to inflate
  • 2. Respiratory Waveforms  Nasal Flow via nasal cannula  Oral/nasal flow via thermistor  Effort via esophageal pressure (not often used)  Rib cage and abdominal movement via RIP (respiratory inductive plethysmograph)
  • 3. Rib cage and abdominal belts (RIP)  During quiet, unobstructed breathing the belts move in and out together. This reflects the RC(rib cage) and Ab(abdomen) expanding and relaxing together.  With partial obstruction the belts can begin to move out of phase with each other.
  • 4. Rib cage and abdominal belts (RIP)  With significant or full obstruction the belts will move in paradox; that is one moves out when the other moves in. This is because the airway is now a closed system-the volume doesn’t change. So, if you expand your chest (increasing chest volume) you have to decrease your abdominal volume and vice versa.  Now fill your balloon with air (or water if you like) and tie it off. What happens to the top of the balloon if you squeeze the bottom? What happens to the bottom if you squeeze the top? That is PARADOX!
  • 5. Thermistor  This measures temperature change as air moves in an out.  It can tell you the presence of air flow but cannot give you information about the quality of that flow such as flow limitation.
  • 6. Nasal cannula  Actually measures the pressure changes as air moves past the cannula.  In a closed system like a nasal mask (with no leak) pressure equals flow.  In a small area (like the inside of the nose) pressure is very similar to flow.  This would not work for oral flow because it is not a closed area.  The signal you see is showing the rate of change of the inspiratory and expiratory pressure
  • 7. Unobstructed Airflow measured by mask or nasal canula Inspiratory flow Expiratory flow Zero flow Notice that the unobstructed inspiratory flow (pressure) signal is rounded. As the signal moves up it is showing the flow rate increasing and as the signal moves back to zero the rate of flow is decreasing. The expiratory signal is pointed and gradually returns to zero. Inspiratory flow should always be up.
  • 8. Partially obstructed inspiratory flow (UAR) Notice the concave shape of the inspiratory flow signal This occurs because during inspiration the airway narrows and the rate of inspiratory flow decreases despite increasing effort.
  • 9. Compare the obstructed and unobstructed breaths
  • 10. Esophageal Pressure (Pes)  A balloon on a catheter is placed through the nose into the esophagus.  This pressure reflects the pressure being generated in the larynx.  When you breathe in the negative pressure changes the pressure in the balloon and it returns to normal during relaxed exhalation.  The harder it is to breathe (increased resistance, snoring, upper airway obstruction) the more negative pressure you have to develop to draw in air.
  • 11. Esophageal pressure (Pes) Notice that Pes is negative during inspiratory flow. This indicates the negative (suction) pressure generated by the expansion of the lungs that causes inspiratory flow. Pressure returns to zero during relaxed expiration. The next slide shows you how pressure and flow change from wake to sleep to increased resistance/snoring.
  • 12. Rounded Notice the rounded inspiratory Wake inspiratory flow flow, little effort (Pes-esophageal Little pressure indicates how hard you effort work to pull in air), and RC and AB are in phase RC and AB in phase Sleep- The airway is still open although open breathing frequency is higher than awake – rounded flow, little airway effort, and RC and AB are still in phase Notice now the inspiratory flow Insp. Flow is collapsed Sleep- Indicating flow limitation signal is not rounded but is Flow collapsed a little, Pes is bigger Greater pressure indicating much more pressure limitation Development means more work has to be developed to breath and RC and AB out of RC and AB are paradoxing phase
  • 13. Respiratory belts, airflow and respiratory effort (Pes) when partial obstruction resolves This picture shows an individual moving from partial obstruction to a fully open airway. Notice that when airflow (measured by nasal pressure in the first few breaths of channel “e”) shows flow limitation – the RC (a) and AB (b) are in paradox. The pressure developed (f) is large. In the last breath, with no flow limitation, the belts are in phase and little pressure is developed
  • 14. Why does this happen? Remember:  The upper airway is composed partially of muscle.  Upper airway muscles relax in sleep  This allows the airway to narrow in everyone and in some to partially or fully collapse.  The next slide shows the airway changing from wake to sleep to snoring to hypopnea to apnea. Below that are the effects on flow and pressure.
  • 15. Sleep on the upper airway and its consequences
  • 16. CPAP on the Upper airway  CPAP’s positive airway pressure essentially takes the place of the relaxed muscles to hold open the airway. Get your easy to inflate balloon and blow just enough air in to stretch it a little. Now try it again with the stiffer balloon. Can you tell that it takes more pressure for you to inflate the second balloon?  Peoples airways are like balloons with different degrees of stiffness. This is why they need different levels of PAP.
  • 17. Bilevel Pressure on the Upper Airway  Bilevel pressure is a combination of CPAP (which is the expiratory pressure) and mechanical ventilation which helps to inflate the lungs.  Now blow enough air in one balloon just to hold it open (point A.) That is the CPAP.  Now, holding that pressure inflate your balloon a little (point B) then let the pressure back to point A.  This simulates what bilevel pressure does. It hold the airway pressure at a certain level to keep it open then adds more air pressure during inspiration to increase the size of the breath.