This document provides guidance for UNAIDS on strengthening partnerships with civil society, including key populations and people living with HIV, to help achieve global targets for eliminating HIV/AIDS. It outlines principles, structures, and priorities for meaningful partnership, and minimum standards to operationalize effective collaboration. The guidance is intended to help UNAIDS and its partners deliver on commitments in the 2011 UN Political Declaration on HIV/AIDS and UNAIDS' strategy of Getting to Zero. Effective engagement with civil society is seen as critical to driving major transformations in the AIDS response.