The Joze Jancar memorial lecture on Neurodevelopmental psychiatry given at the 2012 Annual residential conference of the Faculty of Intellectual Disability of the Royal College of Psychiatrists
How should we judge the value of different therapies? Clearly some work better in the short haul, particularly focussing on symptom relief, and some are better at the long haul, where the changes that are might be expected are more secular. Much less is known about what such secular changes are although it has been suggested that they are schemata rather than thoughts, deeper levels of the personality, personality disorders, emotional dispositions, unconscious forces, factors that affect well-being or life-satisfaction in contract to happiness, moods and not emotions, or relationship styles rather than specific relationships.
The lack of clearly specified long haul outcomes means that the effectiveness of psychotherapy over the long term remains difficult to evaluate. In the short-term, using symptom scores as an outcome, most accepted psychotherapy methods produce the same gains although methods that make symptoms their first focus produce these changes more quickly.
Existential counselling for people with autism spectrum disorder precongress ...Dilemma consultancy
Limit situations in autism: aloneness, alienation, lack of autonomy. How can a counsellor help a person with ASD to tackle them--and what can we learn from people with an ASD
How should we judge the value of different therapies? Clearly some work better in the short haul, particularly focussing on symptom relief, and some are better at the long haul, where the changes that are might be expected are more secular. Much less is known about what such secular changes are although it has been suggested that they are schemata rather than thoughts, deeper levels of the personality, personality disorders, emotional dispositions, unconscious forces, factors that affect well-being or life-satisfaction in contract to happiness, moods and not emotions, or relationship styles rather than specific relationships.
The lack of clearly specified long haul outcomes means that the effectiveness of psychotherapy over the long term remains difficult to evaluate. In the short-term, using symptom scores as an outcome, most accepted psychotherapy methods produce the same gains although methods that make symptoms their first focus produce these changes more quickly.
Existential counselling for people with autism spectrum disorder precongress ...Dilemma consultancy
Limit situations in autism: aloneness, alienation, lack of autonomy. How can a counsellor help a person with ASD to tackle them--and what can we learn from people with an ASD
The presentation focuses on psychopaths- who are they, their traits, brain abnormalities, genetic basis, electrophysiological deficits, socialization function by brain
Connections: The Learning Sciences Platform integrates a humane approach in the educational processes through creative initiatives using an interdisciplinary and international perspective.
Connections work is focus on:
- Educational Support “in situ”
- Professional Development
- Educational Research
- Promotion of free resources to improve the learning sciences
Visit our social networks
- Website: http://thelearningsciences.com
- Facebook: https://www.facebook.com/connectionstlsp/
- Instagram: ConexionesPCA2017
- Slideshare: https://www.slideshare.net/Lascienciasdelaprendizaje
- YouTube: https://www.youtube.com/channel/UCyUDsQmjsiJl8T2w5-EF78g
- Linkedin: https://www.linkedin.com/company-beta/16212567/
Contact us:
E-mail: info@thelearningsciences.com
Mobile: +593 995 615 247
Empathy is the capacity to understand or feel what another person is experiencing from within their frame of reference, that is, the capacity to place oneself in another's position
Earle Waugh Evil As A Treatable DiseaseKim Solez ,
Dr. Earle Waugh's presentation on Evil As A Treatable Disease for January 24th, 2013 in the Technology and Future of Medicine course LABMP 590 http://www.singularitycourse.com at the University of Alberta in Edmonton Canada
Psychoanalysis
The relational focus was there from the beginning.
In between Biology and Psychology: genetic vulnerabilities in interaction with the primary caregivers.
How do somatic sensations develop into human feelings?
How do emotions develop into feelings?
How develop somatic sensations into intentional behavior with a symbolic meaning?
How do biological factors, genetic vulnerabilities and environmental factors interact with each other?
Understanding EmotionalIntelligence in Educational Contextinventionjournals
Emotional intelligence (EI), the recent origin concept in the field of social and Behavioural science, is getting more and more popularity in research, business and recruitment purpose. Low predictability of IQ score in real life situation and workplace gave birth the new concept. We have seen that someone who are incredibly bright and intelligent yet cannot seem to pull their life together. As the pace of change is increasing and world of work is making ever greater demands on a person‟s cognitive, emotional and physical resources, this particular set of abilities are becoming increasingly important. Since majority of the concerns in organization involve people in different roles, emotional intelligence must become a determining factor for their effective management. Its importance and relevance in various fields is being scientifically researched and asserted. Yet, the cross-cultural relevance of the concept still remains an unexplored area. In this present paper attempt were made to make a clear understanding regarding the concept, nature, models and implication in the field of education, which will be helpful for in the field of education (in classroom). Though this concept is popular in western country, Indian views regarding EI has also been analyzed in this present paper.
DSM5 focusses more on nonverbal communication in autism spectrum disorder diagnosis, but does not specify what it is about nonverbal communication that is affected. In this presentation, I explain the reflexive nature of nonverbal communication, and why I call this the 'interbrain'. I also provide another explanation for dysempathy in ASD: the inability to recall empathic feelings
The presentation focuses on psychopaths- who are they, their traits, brain abnormalities, genetic basis, electrophysiological deficits, socialization function by brain
Connections: The Learning Sciences Platform integrates a humane approach in the educational processes through creative initiatives using an interdisciplinary and international perspective.
Connections work is focus on:
- Educational Support “in situ”
- Professional Development
- Educational Research
- Promotion of free resources to improve the learning sciences
Visit our social networks
- Website: http://thelearningsciences.com
- Facebook: https://www.facebook.com/connectionstlsp/
- Instagram: ConexionesPCA2017
- Slideshare: https://www.slideshare.net/Lascienciasdelaprendizaje
- YouTube: https://www.youtube.com/channel/UCyUDsQmjsiJl8T2w5-EF78g
- Linkedin: https://www.linkedin.com/company-beta/16212567/
Contact us:
E-mail: info@thelearningsciences.com
Mobile: +593 995 615 247
Empathy is the capacity to understand or feel what another person is experiencing from within their frame of reference, that is, the capacity to place oneself in another's position
Earle Waugh Evil As A Treatable DiseaseKim Solez ,
Dr. Earle Waugh's presentation on Evil As A Treatable Disease for January 24th, 2013 in the Technology and Future of Medicine course LABMP 590 http://www.singularitycourse.com at the University of Alberta in Edmonton Canada
Psychoanalysis
The relational focus was there from the beginning.
In between Biology and Psychology: genetic vulnerabilities in interaction with the primary caregivers.
How do somatic sensations develop into human feelings?
How do emotions develop into feelings?
How develop somatic sensations into intentional behavior with a symbolic meaning?
How do biological factors, genetic vulnerabilities and environmental factors interact with each other?
Understanding EmotionalIntelligence in Educational Contextinventionjournals
Emotional intelligence (EI), the recent origin concept in the field of social and Behavioural science, is getting more and more popularity in research, business and recruitment purpose. Low predictability of IQ score in real life situation and workplace gave birth the new concept. We have seen that someone who are incredibly bright and intelligent yet cannot seem to pull their life together. As the pace of change is increasing and world of work is making ever greater demands on a person‟s cognitive, emotional and physical resources, this particular set of abilities are becoming increasingly important. Since majority of the concerns in organization involve people in different roles, emotional intelligence must become a determining factor for their effective management. Its importance and relevance in various fields is being scientifically researched and asserted. Yet, the cross-cultural relevance of the concept still remains an unexplored area. In this present paper attempt were made to make a clear understanding regarding the concept, nature, models and implication in the field of education, which will be helpful for in the field of education (in classroom). Though this concept is popular in western country, Indian views regarding EI has also been analyzed in this present paper.
DSM5 focusses more on nonverbal communication in autism spectrum disorder diagnosis, but does not specify what it is about nonverbal communication that is affected. In this presentation, I explain the reflexive nature of nonverbal communication, and why I call this the 'interbrain'. I also provide another explanation for dysempathy in ASD: the inability to recall empathic feelings
Psychotherapeutic approaches to helping adults with intellectual disability a...Dilemma consultancy
DSM-5 is likely to provide a dimensional approach to ASD with two main dimensions: social communication disorder, and repetitiveness. ID/ language impairment adds a further dimension. I shall start my talk with a consideration of how a psychotherapeutic orientation can be relevant to these neurodevelopmental dimensions as well as associated neurodevelopmental disorders, particularly ADHD. However, the main value of a psychotherapeutic approach is in relation to the emotional difficulties associated with ASD and ID, and I shall consider particularly the consequences of bullying, exploitation, and marginalization with special attention on the management of anxiety and of seeking to make an impact on others.
An overview of the positive role of anxiety, and how the work of modern European philosophers can inform a unique approach to helping people face up to, and therefore work through, their fear of fear
Emmy's thoughts about the well being and happiness, and the contribution of psychotherapy to it. A presentation given to the Worcester Therapeutic Training Network in February 2010
Psychological disorder in people with Autism Spectrum DisordersDilemma consultancy
An overview of the mental health problems of people with Asperger syndrome: a workshop originally given to senior staff of the National Autistic Society
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
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1. Joze Jancar Memorial Lecture:
Neurodevelopmental psychiatry
Digby Tantam
Professor Emeritus, University of Sheffield
Honorary Senior Visiting Research Fellow,
University of Cambridge
Director, Septimus Ltd
Honorary Consultant Psychiatrist and
Psychotherapist, Sheffield Health and Social Care
NHS Foundation Trust
2. Joze Jancar
• Cross country ski
champion in Slovenia
• Protegee of Iris
Murdoch
• Burden Research
Gold Medal and Prize
• Vice-President and
Honorary Fellow,
RCPsych
• Freeman of the City of
London
3. • 2011, Dr Sylvia Carpenter
• 2010, The Health of Children with Intellectual Disabilities and their Families’,
Professor Sheila Hollins (Immediate Past President, Royal College of
Psychiatrists)
• 2009, ‘Health inequalities: a focus on the remote and rural areas of the UK’,
Professor Richard Collacott
• 2008, Professor Gregory O’Brien, Northgate Hospital, Northumberland
• 2007 Professor Tony Holland, Rights of people with intellectual disability
• 2006, ‘Medical self-regulation in the 21st Century – hallmark of the profession or
archaic artefact’, Dr John Hillery
• 2005, ‘Past, present and future: from stethoscope to crystal ball’, Dr J Calvert.
• 2004,‘People with learning disability: who really cares?’, Dr R A Collacott,
Western Isles Hospital, Stornoway.
• 2003, ‘History of Faculty of Learning Disability as seen through the eyes of Dr
Alan Heaton-Ward’, Dr Alan Heaton-Ward
• 2002, ‘The limits of psychiatry’, Dr Mike Shooter, President, The Royal College of
Psychiatrists, London.
• 2001 Professor Michael Gunn, Nottingham Law School, Nottingham (no available abstract).
• 2000, Dr Leila Cooke, Phoenix NHS Trust Bristol Central (no available abstract).
4. Me?
• General psychiatrist, rehabilitation, intensive care
unit, community mental health team founder,
service for transgender people, service for people
who repeatedly self-wound, group analyst,
consultant psychotherapist, director of general
psychiatry training, psychiatrist to University of
Warwick…
• FBPsS
• providing assessment service for people,
especially adults, suspected of having ASD since
1981
6. • From the Description of Mike Shooter’s Joze
Jancar Memorial Lecture:
• “At the same time, the lecture suggests ways in
which Psychiatry has shifted the borders between
itself, politics and social morality - in its lack of
clarity between social problems, psychiatric need
and service possibilities, and in systems of
classification (ICD and DSM) that hover
uncertainly over the inevitable consequences of
deprivation (conduct disorder), the normal
reactions to catastrophe (grief and PTSD) and a
hotch-potch of mysticism, philosophy and
historical empire-building (personality disorder)”.
7. Psychiatry is a medical speciality
• We are not primarily, and we are not trained to
be:
• Social workers, or sociologists
• Ethicists
• Politicians
• Leaders and managers (well, not so many of us)
• Historians
• Service planners
• Counsellors or psychotherapists
• Psychologists
8. Clinical pathology in mental retardation
Eastham, R. and Jancar, J.
• Nonspecific Laboratory Findings in Mentally 5
• Disorders of Lipid Metabolism 100
• Disorders of Carbohydrate Metabolism 133
• Disorders of Endocrine Metabolism 165
• Disorders of Metabolism of Connective Tissue 184
• Chromosomal Anomalies 195
• Other Conditions known to cause Mental handicap 208
• 210 Infections 216 Disturbance of Immunity 263 Disorders
of Liver Metabolism 268 Disorders of Pancreatic function
281 Disorders of Folic Acid and Related Anaemias 299
Erythrocyte Abnormalities 305 Leucocyte Abnormalities 309
• Conditions known to be associated with Mental disorder
335
9. Intellectual disabilities
• Are of interest as forms of existence, of
interest in itself, and not just as a sign of
underlying derangement
• Inborn errors of metabolism giving way to
SNPs
• Recent reports of SNPs on random trawls with
microarrays suggest frequencies of people with ID
and SNPs to be between 0.8 and 8% (the latter
with ADHD)
• Very many possible SNPs, if ASD is anything
to go by—so no small number of pathologies
10. • Some of us become these things, of course
• Some of us even have further training to
become these things
• So what are we primarily?
• In the past, this has been a problem because
what is there to psychiatry that is over and
above being wise and decent?
• Not pathology
11. Where the wetware meets the
software
• Where the neuroscientists and the
neurogeneticists are—
• And where the medicine of intellectual
disability needs to be
12. Why medicine and not psychology?
• A reliance on observation and deduction,
and not testing
• The importance of emotion in altering
cognitive states
• Mess?
13. Montague PR, Dolan RJ, Friston KJ, Dayan P. Computational psychiatry.
Trends in Cognitive Sciences. 2012;16(1):72-80
16. Working memory
• Perceptual and verbal
• Processed (links with perceptual cortex) but still short-
term memory
• Required for pre-processing memories for hippocampal
and then cortical storage
• Not correlated with intelligence
• Affected by anxiety
• Affected by practice
17. Working memory
• Verbal working memory involved in parsing phrases (Fernell, E.,
Norrelgen, F., Bozkurt, I. et al, 2002;Adams, A. M. and Gathercole, S.
E., 2000), language learning {Cohen, 2000 #14361}, mental
arithmetic, following instructions, returning to a task after an
interruption, ‘multitasking’ (actually switching attention from one task
to another, but maintaining a ‘tab’ on each task to mark progress so
that switching goes back to the point of the time and money
budgetting, organization and planning
• Dysexecutive problems, secondary to reduced working memory, are
common causes of failure of independent living
• Improved by practice
• Splinted by note pads, personal organizers, phones
18. • These results suggest that when presented with a complex scene consisting of items from
a variety of categories, the underlying representations of those categories will compete for
representation. When those representations do not overlap, there is little to no competition
and an increase in behavioral performance is obtained. However, when those
representations do overlap, they interact in a mutually suppressive manner, which leads to
difficulty remembering the items
• http://tech.groups.yahoo.com/group/boston-neurotalks/message/6820
20. Narrative
• IQ 60
• Recent severe hypoxic episode
• Parents rowed, sometimes about him
• He said, ““I do get worried about something
happening to mum… I’ve got fits haven’t I, I
can’t protect my mum, what if she’s old”.
23. The orbitofrontal cortex as cache? fNIRS evidence
Brink, T. T., Urton, K., Held, D., Kirilina, E., Hofmann, M. J., Klann-Delius, G., et al. (2011). The role of
orbitofrontal cortex in processing empathy stories in 4- to 8-year-old children. Front Psychol, 2, 80.
Negative
affective
empathy
Positive
affective
empathy
Logical
cognitive
empathy
Non-
logical
cognitive
empathy
24. Two kinds of empathy: fNIRS evidence
Brink, T. T., Urton, K., Held, D., Kirilina, E., Hofmann, M. J., Klann-Delius, G., et al. (2011). The role of
orbitofrontal cortex in processing empathy stories in 4- to 8-year-old children. Front Psychol, 2, 80.
Similar picture for auditory stimuli
29. Perlman, S. B., Hudac, C. M., Pegors, T., Minshew, N. J., & Pelphrey, K. A. (2011). Experimental
manipulation of face-evoked activity in the fusiform gyrus of individuals with autism. Soc
Neurosci, 6(1), 22-30.
30.
31. Schurmann M, Hesse MD, Stephan KE, Saarela M, Zilles K, Hari R, et al.
Yearning to yawn: the neural basis of contagious yawning. Neuroimage. [doi:
DOI: 10.1016/j.neuroimage.2004.10.022]. 2005;24(4):1260-4.
33. • Neurons are linked by electrical impulses and
chemicals into a network
• Our brains can be linked to other brains the
way that one computer can be linked to
another via the internet
• These links are the nonverbal communications
that pass between us, principally consisting of
imitation and of gaze following
• Imitation and gaze following are automatically
initiated by local brain networks apparently
specialized for this
34. Morishima Y, Schunk D, Bruhin A, Ruff CC, Fehr E. Linking Brain
Structure and Activation in Temporoparietal Junction to Explain the
Neurobiology of Human Altruism. Neuron. 2012;75(1):73-9.
36. • Psychiatry needs to overcome its identity crisis
• And shrug off its alienist function
• Needs, in fact, to have an organ or physical
function in which it specializes
• The interface between wetware and software/
brain and consciousness provides this
• Intellectual disability stands to gain particularly
• Let’s dust off our observational skills
• Add a pinch of wisdom about emotions
• Start to identify ‘modules’ of higher order
functioning