Roundup Ready Maize symposium: The European Perspective




          Current and future role of the
         non-selective use of glyphosate
                                        Jim Orson




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




              “All our attempts at couch control by
                  cultivation have been fruitless.”

                         Andrew Charlton, Farmer’s Weekly
                                  January 2009




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




                                Glyphosate

• 1974 - introduced in UK for perennial weed control
• 1980 - pre-harvest application introduced




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




Reduction (%) of common couch shoots in the following
season after pre-harvest or post-harvest application of
 a range of doses (kg ae/ha) of glyphosate in 1979 in
       Scotland (Source; O’Keeffe et al., 1981)

          Site                      Pre-harvest             Post-harvest
                             0.72             1.44        0.72        1.44


          1                  99.7             99.7        95.1        97.8
          2                  98.8             98.4        64.5        89.6
          3                  99.4             99.2        31.6        93.7
          4                     -             90.0         -          60.0

     © Copyright text
Roundup Ready Maize symposium: The European Perspective




      Glyphosate – a few properties
     Solubility in water (20oC) = 10,500 mg/l
     Koc = non-mobile
     GUS leaching potential index = -0.36
     Potential for particulate bound transport = medium




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




      UK competitiveness based on technology
                            Average wheat yields (t/ha)
                 t/ha           Effective
         9
               Effective       fungicides
         8
               herbicides
         7
         6
         5                              Increase in N
         4
         3
         2
                           Semi-dwarf
         1
                            varieties
         0
       68



                      73



                               78



                                       83



                                               88



                                                            93



                                                                   98



                                                                          03



                                                                                 08
     19



                    19



                             19



                                     19



                                             19



                                                          19



                                                                 19



                                                                        20



                                                                               20
     © Copyright text
Roundup Ready Maize symposium: The European Perspective




  % of winter wheat in England established
           after non-plough tillage
  45
  40
  35
  30
  25
  20
  15
  10
   5
   0
 19 5
 19 6
 19 7
 19 8
 19 9
 19 0
 19 1
 19 2
 19 5
 19 6
 19 7
 19 8
 19 9
 19 0
 19 1
 19 2
 19 3
 19 4
 19 5
 19 6
 19 7
 19 8
 20 9
 20 0
 20 1
 20 2
 20 3
 20 4
 20 5
 20 6
 20 7
    08
    7
    7
    7
    7
    7
    8
    8
    8
    8
    8
    8
    8
    8
    9
    9
    9
    9
    9
    9
    9
    9
    9
    9
    0
    0
    0
    0
    0
    0
    0
    0
 19




Source:
       © Copyright text
Roundup Ready Maize symposium: The European Perspective




  % of winter wheat crops in England sown in September and
       before 20th September, 1970-2008 harvest years
                        60

                        50             September
                                       Before 20/09
    Crops drilled (%)




                        40

                        30

                        20

                        10

                         0
                         70

                              72
                                   74

                                        76
                                             78
                                                  80
                                                       82

                                                            86
                                                                 88

                                                                      90
                                                                           92

                                                                                94

                                                                                     96
                                                                                          98
                                                                                               00

                                                                                                    02
                                                                                                         04

                                                                                                              06
                                                                                                                   08
                        19
                             19

                                  19
                                       19

                                            19
                                                 19

                                                      19
                                                           19

                                                                19
                                                                     19

                                                                          19
                                                                               19

                                                                                    19
                                                                                         19
                                                                                              20
                                                                                                   20

                                                                                                        20
                                                                                                             20

                                                                                                                  20
Source:
         © Copyright text
Roundup Ready Maize symposium: The European Perspective




                                Glyphosate
     • Introduced in UK for perennial weed control in
       1974
     • Pre-harvest application introduced in 1980
     And then it got cheaper!
     • Subsequently used for annual grass and
       broad-leaved weed control and crop
       dessication
     • Glyphosate residues commonly occur in UK
       bread (below MRLs)

     © Copyright text
Roundup Ready Maize symposium: The European Perspective




Percentage of bread samples (ordinary and speciality)
     containing glyphosate residues, 2000-2006




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




   Wheat yield (t/ha @ 85% MC) and moisture content (%) of
  grain at harvest of Consort wheat, treated or not treated with
  1.0 l/ha Roundup (360 g ae/l glyphosate) when the bulk grain
   content of the site was 30% moisture content; Morley 1999

     Fungicide programme                1.0 l/ha          Yield    % moisture
                                       Roundup            (t/ha)


     No                                    No             6.52       18.23
     No                                   Yes             6.32       14.96
     Non-strob                             No             7.31       17.34
     Non-strob                            Yes             6.81       14.91
     Strob                                 No             8.44       17.01
     Strob                                Yes             7.68       15.45

     © Copyright text
Roundup Ready Maize symposium: The European Perspective




   Wheat yield (t/ha @ 85% MC) and moisture content (%) of
  grain at harvest of Consort wheat, treated or not treated with
  1.0 l/ha Roundup (360 g ae/l glyphosate) when the bulk grain
   content of the site was 30% moisture content; Morley 1999

     Fungicide programme                1.0 l/ha           Yield    % moisture
                                       Roundup             (t/ha)


     No                                    No            No 6.52      18.23
     No                                   Yes        impact6.32
                                                             on       14.96
     Non-strob          MOG                No          quality
                                                            7.31      17.34
     Non-strob                            Yes         in clean
                                                            6.81      14.91
     Strob                                 No          crops8.44      17.01
     Strob                                Yes               7.68      15.45

     © Copyright text
Roundup Ready Maize symposium: The European Perspective




  % of winter wheat in England established
           after non-plough tillage
  45
  40                                                        The value
  35                                                         of stale
  30                                                       seedbeds?
  25
  20
                              Cereals
  15                        Rye-grass
  10                       Barren brome
   5                      Meadow brome -                   Seeds can
   0                            No                           be lost
                           Black-grass?                     without
 19 5
 19 6
 19 7
 19 8
 19 9
 19 0
 19 1
 19 2
 19 5
 19 6
 19 7
 19 8
 19 9
 19 0
 19 1
 19 2
 19 3
 19 4
 19 5
 19 6
 19 7
 19 8
 20 9
 20 0
 20 1
 20 2
 20 3
 20 4
 20 5
 20 6
 20 7
    08
    7
    7
    7
    7
    7
    8
    8
    8
    8
    8
    8
    8
    8
    9
    9
    9
    9
    9
    9
    9
    9
    9
    9
    0
    0
    0
    0
    0
    0
    0
    0
 19




                            Wild-oats?                      creating
Source:
       © Copyright text                                      plants
Roundup Ready Maize symposium: The European Perspective




                         Post-drilling use
     • Convenience – rather than improved weed
       control
     • Maize in France:
             – up to 48 hours after drilling provided soil has more
               than 10% clay (<24 hours and max dose of less
               than 360 g ae/ha if soil is sandy)
             – soil well structured and seed well covered




     © Copyright text
Roundup Ready Maize symposium: The European Perspective



 Most likely active substances to fail re-registration as
            a result of the revision of 91/414
  •   2,4-D? (2011)            •   Flumioxazine (2012)     • Metribuzin? (2017)
  •   Amitrole?? (2011)        •   Fluquinconazole? (2020) • Pendimethalin (2013)*
  •   Carbendazim (2009)*      •   Flusilazole (not sure)  • Picloram? (2018)
  •
  •
      Carbetamide? (2020)
      Chlorotoluron? (2016)
                               •                  plus
                                   Glufosinate (2017)      • Prochloraz? (2020)
                                                           • Prothioconazole? (2018)
                               •   Ioxynil?? (2015)
  •   Cyproconazole??
      (2020)                   •
                                                 Water
                                   Ipridione?? (2013)
                                                           • Quinoxyfen (2014)*
                                                           • Tebuconazole?? (2018)
  •
  •
      Deltamethrin? (2013)
      Dimethoate? (2016)
                               •               Framework
                                   Linuron (2013)          • Tepraloxydim? (2015)
                                                           • Thiram? (2013)
                               •   Mancozeb?? (2016)
  •
  •
      Dinocap (2009)
      Epoxiconazole??
                               •                Directive
                                   Maneb?? (2016)          • Triflusulfuron? (2018)
      (2018)                   •   Metconazole?? (2017)
                                                           * = no derogation
  •   Esfenvalerate (2011)*
  ? = endocrine disruptor on PSD assessment
  ?? = endocrine disruptor on both PSD and Swedish assessment
  Other active substances may be subject to candidates for substitution
  – particularly most insecticides
      © Copyright text
Roundup Ready Maize symposium: The European Perspective



    % reduction in black-grass heads from the application of
  2,500 g/ha isoproturon at GS 11-13 of the weed – individual
       TAG trials 1996-2007 (blue) and average (green)
      100
       90
       80
       70
       60
       50
       40
       30
       20
       10
        0
               19

                        19

                               19

                                      19

                                             20

                                                    20

                                                           20

                                                                  20

                                                                         20

                                                                                20

                                                                                       20

                                                                                              20
                 96

                          97

                                 98

                                        99

                                               00

                                                      01

                                                             02

                                                                    03

                                                                           04

                                                                                  05

                                                                                         06

                                                                                                07
     © Copyright text
Roundup Ready Maize symposium: The European Perspective




   % reduction in black-grass heads from the application of 2.5
    l/ha Hawk at GS 11-13 of the weed – individual TAG trials
            1996 – 2004 (blue) and average (green)
      100
       90
       80
       70
       60
       50
       40
       30
       20
       10
        0
            19


                     19


                              19


                                      19


                                               20


                                                          20


                                                                 20


                                                                        20


                                                                               20
              96


                       97


                                98


                                        99


                                                 00


                                                            01


                                                                   02


                                                                          03


                                                                                 04
No. trials text 3
      © Copyright
                          4       5       6         8        8      9      6      3
Roundup Ready Maize symposium: The European Perspective




Cases of resistance to ‘Atlantis’
(mesosulfuron+iodosulfuron) in
black-grass in the UK by 2008
(‘Atlantis’ introduced autumn 2003)



  •   >250 cases confirmed in pot tests
  •   In 21 counties
  •   Most not ‘field failures’
  •   Target site resistance (Pro197) confirmed on 10
      farms
  •   Target site resistance (Trp574) confirmed on 1 farm
  •   Both target site mutations
       (Pro197 & Trp574 ) on 1 farm
  •   Enhanced metabolism also probable
  •   79% also ACCase (‘fop’/‘dim’) TSR

        © Copyright text

Compilation of Bayer, Syngenta and Rothamsted results
Roundup Ready Maize symposium: The European Perspective




    The future – do we need a Plan B?
  • Need to embrace new technologies (e.g.
    remote sensing and GM) in addition to
    refining current technologies to reduce
    dose/ha of key active substances
  • Need to build up fertility in soils in order to:
       – sustain/increase yields
       – increase flexibility of cropping




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




     © Copyright text
Roundup Ready Maize symposium: The European Perspective




                                Glyphosate

      35 years on and still developing new
              uses and approaches




     © Copyright text

J Orson

  • 1.
    Roundup Ready Maizesymposium: The European Perspective Current and future role of the non-selective use of glyphosate Jim Orson © Copyright text
  • 2.
    Roundup Ready Maizesymposium: The European Perspective © Copyright text
  • 3.
    Roundup Ready Maizesymposium: The European Perspective “All our attempts at couch control by cultivation have been fruitless.” Andrew Charlton, Farmer’s Weekly January 2009 © Copyright text
  • 4.
    Roundup Ready Maizesymposium: The European Perspective Glyphosate • 1974 - introduced in UK for perennial weed control • 1980 - pre-harvest application introduced © Copyright text
  • 5.
    Roundup Ready Maizesymposium: The European Perspective Reduction (%) of common couch shoots in the following season after pre-harvest or post-harvest application of a range of doses (kg ae/ha) of glyphosate in 1979 in Scotland (Source; O’Keeffe et al., 1981) Site Pre-harvest Post-harvest 0.72 1.44 0.72 1.44 1 99.7 99.7 95.1 97.8 2 98.8 98.4 64.5 89.6 3 99.4 99.2 31.6 93.7 4 - 90.0 - 60.0 © Copyright text
  • 6.
    Roundup Ready Maizesymposium: The European Perspective Glyphosate – a few properties Solubility in water (20oC) = 10,500 mg/l Koc = non-mobile GUS leaching potential index = -0.36 Potential for particulate bound transport = medium © Copyright text
  • 7.
    Roundup Ready Maizesymposium: The European Perspective UK competitiveness based on technology Average wheat yields (t/ha) t/ha Effective 9 Effective fungicides 8 herbicides 7 6 5 Increase in N 4 3 2 Semi-dwarf 1 varieties 0 68 73 78 83 88 93 98 03 08 19 19 19 19 19 19 19 20 20 © Copyright text
  • 8.
    Roundup Ready Maizesymposium: The European Perspective % of winter wheat in England established after non-plough tillage 45 40 35 30 25 20 15 10 5 0 19 5 19 6 19 7 19 8 19 9 19 0 19 1 19 2 19 5 19 6 19 7 19 8 19 9 19 0 19 1 19 2 19 3 19 4 19 5 19 6 19 7 19 8 20 9 20 0 20 1 20 2 20 3 20 4 20 5 20 6 20 7 08 7 7 7 7 7 8 8 8 8 8 8 8 8 9 9 9 9 9 9 9 9 9 9 0 0 0 0 0 0 0 0 19 Source: © Copyright text
  • 9.
    Roundup Ready Maizesymposium: The European Perspective % of winter wheat crops in England sown in September and before 20th September, 1970-2008 harvest years 60 50 September Before 20/09 Crops drilled (%) 40 30 20 10 0 70 72 74 76 78 80 82 86 88 90 92 94 96 98 00 02 04 06 08 19 19 19 19 19 19 19 19 19 19 19 19 19 19 20 20 20 20 20 Source: © Copyright text
  • 10.
    Roundup Ready Maizesymposium: The European Perspective Glyphosate • Introduced in UK for perennial weed control in 1974 • Pre-harvest application introduced in 1980 And then it got cheaper! • Subsequently used for annual grass and broad-leaved weed control and crop dessication • Glyphosate residues commonly occur in UK bread (below MRLs) © Copyright text
  • 11.
    Roundup Ready Maizesymposium: The European Perspective Percentage of bread samples (ordinary and speciality) containing glyphosate residues, 2000-2006 © Copyright text
  • 12.
    Roundup Ready Maizesymposium: The European Perspective Wheat yield (t/ha @ 85% MC) and moisture content (%) of grain at harvest of Consort wheat, treated or not treated with 1.0 l/ha Roundup (360 g ae/l glyphosate) when the bulk grain content of the site was 30% moisture content; Morley 1999 Fungicide programme 1.0 l/ha Yield % moisture Roundup (t/ha) No No 6.52 18.23 No Yes 6.32 14.96 Non-strob No 7.31 17.34 Non-strob Yes 6.81 14.91 Strob No 8.44 17.01 Strob Yes 7.68 15.45 © Copyright text
  • 13.
    Roundup Ready Maizesymposium: The European Perspective Wheat yield (t/ha @ 85% MC) and moisture content (%) of grain at harvest of Consort wheat, treated or not treated with 1.0 l/ha Roundup (360 g ae/l glyphosate) when the bulk grain content of the site was 30% moisture content; Morley 1999 Fungicide programme 1.0 l/ha Yield % moisture Roundup (t/ha) No No No 6.52 18.23 No Yes impact6.32 on 14.96 Non-strob MOG No quality 7.31 17.34 Non-strob Yes in clean 6.81 14.91 Strob No crops8.44 17.01 Strob Yes 7.68 15.45 © Copyright text
  • 14.
    Roundup Ready Maizesymposium: The European Perspective % of winter wheat in England established after non-plough tillage 45 40 The value 35 of stale 30 seedbeds? 25 20 Cereals 15 Rye-grass 10 Barren brome 5 Meadow brome - Seeds can 0 No be lost Black-grass? without 19 5 19 6 19 7 19 8 19 9 19 0 19 1 19 2 19 5 19 6 19 7 19 8 19 9 19 0 19 1 19 2 19 3 19 4 19 5 19 6 19 7 19 8 20 9 20 0 20 1 20 2 20 3 20 4 20 5 20 6 20 7 08 7 7 7 7 7 8 8 8 8 8 8 8 8 9 9 9 9 9 9 9 9 9 9 0 0 0 0 0 0 0 0 19 Wild-oats? creating Source: © Copyright text plants
  • 15.
    Roundup Ready Maizesymposium: The European Perspective Post-drilling use • Convenience – rather than improved weed control • Maize in France: – up to 48 hours after drilling provided soil has more than 10% clay (<24 hours and max dose of less than 360 g ae/ha if soil is sandy) – soil well structured and seed well covered © Copyright text
  • 16.
    Roundup Ready Maizesymposium: The European Perspective Most likely active substances to fail re-registration as a result of the revision of 91/414 • 2,4-D? (2011) • Flumioxazine (2012) • Metribuzin? (2017) • Amitrole?? (2011) • Fluquinconazole? (2020) • Pendimethalin (2013)* • Carbendazim (2009)* • Flusilazole (not sure) • Picloram? (2018) • • Carbetamide? (2020) Chlorotoluron? (2016) • plus Glufosinate (2017) • Prochloraz? (2020) • Prothioconazole? (2018) • Ioxynil?? (2015) • Cyproconazole?? (2020) • Water Ipridione?? (2013) • Quinoxyfen (2014)* • Tebuconazole?? (2018) • • Deltamethrin? (2013) Dimethoate? (2016) • Framework Linuron (2013) • Tepraloxydim? (2015) • Thiram? (2013) • Mancozeb?? (2016) • • Dinocap (2009) Epoxiconazole?? • Directive Maneb?? (2016) • Triflusulfuron? (2018) (2018) • Metconazole?? (2017) * = no derogation • Esfenvalerate (2011)* ? = endocrine disruptor on PSD assessment ?? = endocrine disruptor on both PSD and Swedish assessment Other active substances may be subject to candidates for substitution – particularly most insecticides © Copyright text
  • 17.
    Roundup Ready Maizesymposium: The European Perspective % reduction in black-grass heads from the application of 2,500 g/ha isoproturon at GS 11-13 of the weed – individual TAG trials 1996-2007 (blue) and average (green) 100 90 80 70 60 50 40 30 20 10 0 19 19 19 19 20 20 20 20 20 20 20 20 96 97 98 99 00 01 02 03 04 05 06 07 © Copyright text
  • 18.
    Roundup Ready Maizesymposium: The European Perspective % reduction in black-grass heads from the application of 2.5 l/ha Hawk at GS 11-13 of the weed – individual TAG trials 1996 – 2004 (blue) and average (green) 100 90 80 70 60 50 40 30 20 10 0 19 19 19 19 20 20 20 20 20 96 97 98 99 00 01 02 03 04 No. trials text 3 © Copyright 4 5 6 8 8 9 6 3
  • 19.
    Roundup Ready Maizesymposium: The European Perspective Cases of resistance to ‘Atlantis’ (mesosulfuron+iodosulfuron) in black-grass in the UK by 2008 (‘Atlantis’ introduced autumn 2003) • >250 cases confirmed in pot tests • In 21 counties • Most not ‘field failures’ • Target site resistance (Pro197) confirmed on 10 farms • Target site resistance (Trp574) confirmed on 1 farm • Both target site mutations (Pro197 & Trp574 ) on 1 farm • Enhanced metabolism also probable • 79% also ACCase (‘fop’/‘dim’) TSR © Copyright text Compilation of Bayer, Syngenta and Rothamsted results
  • 20.
    Roundup Ready Maizesymposium: The European Perspective The future – do we need a Plan B? • Need to embrace new technologies (e.g. remote sensing and GM) in addition to refining current technologies to reduce dose/ha of key active substances • Need to build up fertility in soils in order to: – sustain/increase yields – increase flexibility of cropping © Copyright text
  • 21.
    Roundup Ready Maizesymposium: The European Perspective © Copyright text
  • 22.
    Roundup Ready Maizesymposium: The European Perspective Glyphosate 35 years on and still developing new uses and approaches © Copyright text