intravenus route f drug administration, prepared by Ashish kumar sharma bpt 2nd year Noida international university

1. INTRAVENOUS ROUTE OF DRUG
ADMINISTRATION
Prepared By-
Ashish kumar Sharma
BPT 2nd year

2. DEFINITION
• Intravenous route is a systematic route
of drug administration in which the drug
is directly given into the blood stream
through veins.

3. DRUG CAN BE GIVEN INTRAVENOUSLY AS
;-
• Bolus
• Slow I.V Injection
• I.V Infusion

4. ADVANTAGES OF I.V ROUTES
• 100% Bioavailability
• Quick onset of action
• Large volume of fluids
• Highly irritant drugs (Anti cancer drug)
• Hypertonic Solution (20% Manitol)
• Constant plasma level can be
maintained by Infusion.

5. DISADVANTAGES OF IV ROUTES
• Phlebitis (Inflammation of vein)
• Self administration is not possible
• Strict Aseptic Condition needed
• Injury narcosis of tissue
• Depot preparation can not be given

6. SIDE EFFECTS
• Infection
• Damage to blood vessels and injection
site
• Air embolism
• Blood clots

7. PHARMACOKINETICS
• It is the study of time, course of drug
absorption, distribution, Metabolism and
excretion.

8. PHARMACODYNAMICS
• Pharmacodynamics is the study of drug
effects. It states that how does the drug
is effecting towards the body .

9. MANY DIFFERENT TYPES OF
MEDICATIONS CAN BE GIVEN BY IV.
SOME OF THE DRUGS MORE
COMMONLY GIVEN BY THIS METHOD
INCLUDE

10. SOME COMMONLY USED I.V
• 0.9% Normal saline (NS, 0.9NaCl, or NSS)
• Lactated Ringers (LR) or Ringers Lactate (RL)
• 5% Dextrose in water (D5 or D5W)
• 0.45% Normal saline (Half Normal saline,
0.45NaCl, .45NS)

11. CHEMOTHERAPY DRUGS SUCH AS:-
• Doxorubicin
• Vincristine
• Cisplatin
• Paclitaxe

12. ANTIBIOTICS SUCH AS:-
• Vancomycin
• Meropenem
• Gentamicin

13. ANTIFUNGAL DRUGS SUCH AS
• Micafungin
• Amphotericin

14. PAIN MEDICATIONS SUCH AS:-
• Hydromorphone
• Morphine

15. DRUGS FOR LOW BLOOD PRESSURE
SUCH AS:-
• Dopamine
• Epinephrine
• Norepinephrine
• Dobutamine

16. THANK YOU