21. Ultrasonic Nebulizers •
• The temperature can rise 10-15°C over a
10- minute treatment period, which may
adversely affect heat-sensitive
components of formulations
• Ultrasonic nebulizers also are not suitable
for nebulizing suspensions
22. • Breath-Actuated Nebulizers
• generate aerosol only during inspiration
New-generation nebulizers Soft Mist
Inhalers
• uses mechanical energy to create an
aerosol with a low-velocity spray
• aerosol ranges 2.2-5.5 μm MMD Middleton
8th edition
23. • Vibrating Mesh Devices:
• Passive • generate aerosol only during
inspiration Vibrating Mesh Devices
• Active • vibrates at a high frequency
• high FPFs and very low dead volumes •
battery-operated
