The document discusses how the body defends itself against pathogens through multiple systems. The skin, mucus, stomach acids, and reflexes like sneezing provide the first line of defense against pathogens entering through openings. When pathogens breach these defenses, the immune system is triggered to increase white blood cells and antibodies that target specific pathogens for destruction. The document also briefly mentions how different body systems like respiratory, circulatory, endocrine, digestive, nervous, muscular and skeletal work together to keep the body healthy.