19. Summary
・PCA based unsupervisedunsupervised FE identified more genes
associated with both differential gene expression
and aberrant promoter methylation between E13
and E16 rat F3 generation vinclozolin lineage
・ Genes selected by PCA based unsupervisedunsupervised FE
were associated with various enrichments of
biological terms/concepts while none were
associated with those selected by ttest, limma, or
SAM based FE.
・ These suggested definitely the superiority of
unsupervisedunsupervised method toward supervised methods.