This document describes a simulation study done using COMSOL Multiphysics to design a nanosensor for detecting blood glucose levels. A 2D axisymmetric model of the sensor embedded in a blood medium is created. Pressure acoustics and piezoelectric device physics are applied. Meshing and frequency domain analysis are performed to study the acoustic pressure, displacement, and electric potential at different eigenfrequencies. The results are intended to help optimize sensor design for non-invasively monitoring blood glucose levels. Further studies incorporating additional factors like stress and strain distribution are suggested to more accurately detect glucose concentration in blood.