The document discusses single nucleotide polymorphisms (SNPs) that exist within predicted microRNA (miRNA) target sites in the human genome. It hypothesizes that SNPs within target sites may functionally affect gene expression and may be biased toward occurring in the conserved "seed region" of miRNA binding. The document outlines gathering data on miRNA targets from miRBase and SNPs from HapMap to identify SNPs within target sites and perform statistical analyses to test if a bias exists toward the seed region. It proposes several future studies analyzing the effects of target site SNPs.