The human heart has four chambers - two atria that receive blood and two ventricles that pump blood. The right side receives deoxygenated blood from the body and pumps it to the lungs, while the left side receives oxygenated blood from the lungs and pumps it to the body. The heart is made of cardiac muscle that can contract regularly without fatigue. Blood returns to the heart through the vena cavae and pulmonary veins and is pumped back out through the pulmonary artery and aorta.