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Tumors in HIV
Risk for HIV/AIDS cancer
• They have high risk to develop some types of
cancer:
• Kaposi sarcoma
• Non-Hodgkin lymphoma
• Cervical cancer
• Less common: Hodgkin lymphoma,
angiosarcoma and types of skin cancer
Kaposi sarcoma
• Most common HIV/AIDS-related cancer
• More common in men than women
• Cases have decreased after HIV treatment has
improved
• In the beginning when AIDS became widespread the
five-year survival rate was <10%
• Now the the five-year survival rate was >72%
• Often HIV patients die from other diagnosis than this
sarcoma, even if they have Kaposi sarcoma as well
Kaposi sarcoma
symptoms
• Colored lesions around the mouth/throat
• Lymphedema, mostly arm or leg
• Unexplained cough or chest pain
• Unexplained stomach or intestinal pain
• Unexplained bleeding from mouth or rectum
• Diarrhea and/or blockage of the digestive tract
Non-Hodgkin lymphoma
• Second most common type
• 57% of NHL patients already have AIDS
• 30% are diagnosed with NHL and AIDS at the
same time
• Antiretroviral therapy (HAART) has decreased
the occurrence of NHL in HIV patients (before
HAART the mortality rate was close to 100%)
Non-Hodgkin lymphoma
• HIV/AIDS patients have more aggressive
course of the disease
• 59% HIV-NHL patients died within 2 years
• 29% in non-HIV NHL patients
• Recovery chances depends on stage of
lymphoma, , the persons age, the stren
• gth of the immune system, health history
Non-Hodgkin lymphoma
symptoms
• Enlarged lymph nodes in the abdomen, groin,
neck, or underarms
• Enlarged spleen or liver
• Fever that cannot be explained by an infection
or other illness
• Weight loss with no known cause
• Sweating and chills
Symptoms in case of
cervical cancer
• Bloody spots or light bleeding between or following
menstrual periods
• Menstrual bleeding that is longer and heavier than
usual
• Bleeding after sexual intercourse, douching, or a pelvic
examination
• Pain during sexual intercourse
• Bleeding after menopause
• Increased vaginal discharge
Risk factors for cancer
dev. in HIV patient
• HPV infection– risk for cervical cancer.
Transmitted during sex (early age, many
partners, sex with man who has penile warts)
• Prevention: HPV vaccine
• HHV-8 infection – risk for Kaposi sarcoma and
primary effusion lymphoma
• EBV infection – risk for primary central
nervous system lymphoma, high-grade B-cell
lymphoma, and primary effusion lymphoma
Sources
• http://www.cancer.net/cancer-types/hiv-and-
aids-related-cancer
• http://www.cancer.net/cancer-types/hiv-and-
aids-related-cancer/view-all

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Hiv tumours

  • 2. Risk for HIV/AIDS cancer • They have high risk to develop some types of cancer: • Kaposi sarcoma • Non-Hodgkin lymphoma • Cervical cancer • Less common: Hodgkin lymphoma, angiosarcoma and types of skin cancer
  • 3. Kaposi sarcoma • Most common HIV/AIDS-related cancer • More common in men than women • Cases have decreased after HIV treatment has improved • In the beginning when AIDS became widespread the five-year survival rate was <10% • Now the the five-year survival rate was >72% • Often HIV patients die from other diagnosis than this sarcoma, even if they have Kaposi sarcoma as well
  • 4. Kaposi sarcoma symptoms • Colored lesions around the mouth/throat • Lymphedema, mostly arm or leg • Unexplained cough or chest pain • Unexplained stomach or intestinal pain • Unexplained bleeding from mouth or rectum • Diarrhea and/or blockage of the digestive tract
  • 5. Non-Hodgkin lymphoma • Second most common type • 57% of NHL patients already have AIDS • 30% are diagnosed with NHL and AIDS at the same time • Antiretroviral therapy (HAART) has decreased the occurrence of NHL in HIV patients (before HAART the mortality rate was close to 100%)
  • 6. Non-Hodgkin lymphoma • HIV/AIDS patients have more aggressive course of the disease • 59% HIV-NHL patients died within 2 years • 29% in non-HIV NHL patients • Recovery chances depends on stage of lymphoma, , the persons age, the stren • gth of the immune system, health history
  • 7. Non-Hodgkin lymphoma symptoms • Enlarged lymph nodes in the abdomen, groin, neck, or underarms • Enlarged spleen or liver • Fever that cannot be explained by an infection or other illness • Weight loss with no known cause • Sweating and chills
  • 8. Symptoms in case of cervical cancer • Bloody spots or light bleeding between or following menstrual periods • Menstrual bleeding that is longer and heavier than usual • Bleeding after sexual intercourse, douching, or a pelvic examination • Pain during sexual intercourse • Bleeding after menopause • Increased vaginal discharge
  • 9. Risk factors for cancer dev. in HIV patient • HPV infection– risk for cervical cancer. Transmitted during sex (early age, many partners, sex with man who has penile warts) • Prevention: HPV vaccine • HHV-8 infection – risk for Kaposi sarcoma and primary effusion lymphoma • EBV infection – risk for primary central nervous system lymphoma, high-grade B-cell lymphoma, and primary effusion lymphoma