The heart is a hollow muscular organ located in the thorax between the lungs. It has 4 chambers - 2 atria that receive blood and 2 ventricles that pump blood out of the heart. The right side receives deoxygenated blood from the body and pumps it to the lungs, while the left side receives oxygenated blood from the lungs and pumps it out to the body. The heart is surrounded by a membrane called the pericardium which restricts its movement and acts as a lubricated sac. It has 4 valves that ensure one-way blood flow through the heart chambers. The heart is supplied by the left and right coronary arteries and its venous drainage occurs through the coronary sinus into the right atrium.
This presentation is an overview of the description of the 4 stages of the cardiac cycle (atrial diastole, atrial systole, ventricular systole, ventricular diastole) as well as explaining the mechanism of the cardiac cycle.
This presentation is an overview of the description of the 4 stages of the cardiac cycle (atrial diastole, atrial systole, ventricular systole, ventricular diastole) as well as explaining the mechanism of the cardiac cycle.
This presentation will help you to get to known about the human heart in very much clear way. It will help you alot in making your concepts clear regarding the human heart and it's functioning.
The primitive blueprint for the heart and circulatory system emerged with the arrival of the third mesodermal germ layer in bilaterians. Since then, hearts in animals have evolved from a single layered tube to a multiple chambered heart in due course of time.
Enfermedades de Transmisión Sexual en Gestantes y No GestantesAlonso Custodio
- Sindrome de Flujo Vaginal: Tricomoniasis, Candidiasis, Vaginosis Bacteriana, Cervicitis por Chlamydia y Neisseria gonorrhoeae.
- Sindrome de Úlcera Genital: Herpes Simple, Chancro Blando, Chancro Duro, Condiloma Acuminado, etc.
- Enfermedades de la Glándula de Bartholino.
- Enfermedad Pélvica Inflamatoria.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ocular injury ppt Upendra pal optometrist upums saifai etawah
Heart Anatomy
1. HEART ANATOMY Jesús A. Custodio Marroquín By: Dr Mohammed Faez Medical Student VI Cycle – USAT University– Chiclayo – Peru Medical English 1 Jesús A. Custodio Marroquín
2. HEART A hollow muscular organ. Located in thoraxbetween 2 lungs. 4 Chambers. 4 Valves. 2 Atriums & 2 Ventricles. 2 separatepumps (R&L sides) Rightsidereceivesbloodfromthebody and sendsittothelungs (pulmonary) Leftsidereceivesbloodfromlungs and sendsittothebody (systemic) 2 Jesús A. Custodio Marroquín
4. HEART The heart is surrounded by membrane called Pericardium. 4 Jesús A. Custodio Marroquín
5. The Pericardium The pericardium is a fibroserous sac that encloses the heart and the roots of the great vessels. The pericardium lies within the middle mediastinum. 5 Jesús A. Custodio Marroquín
6. The Pericardium Its function is to restrict excessive movements of the heart as a whole and to serve as a lubricated container in which the different parts of the heart can contract. 6 Jesús A. Custodio Marroquín
7. Heart Wall Endocardium deepest layer of the heart smooth lining to reduce friction of bloodflow Myocardium middle layer of the heart location of muscle fibers responsible for pumping Pericardium outer protective layer composed of : visceral pericardium paricardial cavity parietal pericardium 7 Jesús A. Custodio Marroquín
17. the walls of the left ventricle are 3X thicker than those of the right 12 Jesús A. Custodio Marroquín
18.
19. propel blood to Pulmonary Trunk (right ventricle), Aorta (left ventricle) 13 Jesús A. Custodio Marroquín
20. The Right Atrium • Receives deoxygenated blood from the inferior vena cava below and from the superior vena cava above. 14 Jesús A. Custodio Marroquín
21. The Right Ventricle Receives blood from the right atrium through the tricuspid valve . 15 Jesús A. Custodio Marroquín
22. The Left Atrium Receives oxygenated blood from four pulmonary veins which drain posteriorly. 16 Jesús A. Custodio Marroquín
23. The Left Atrium The mitral (bicuspid) valve guards the passage of blood from the left atrium to the left ventricle. 17 Jesús A. Custodio Marroquín
24. The Left Ventricle The wall of the left ventricle is thicker than the right ventricle but the structure is similar. The thick wall is necessary to pump oxygenated blood at high pressure through the systemic circulation. 18 Jesús A. Custodio Marroquín
25. The Heart Valves Heart valves ensure unidirectional blood flow through the heart Composed of an endocardium with a connective tissue core. Two major types Atrioventricular valves Semilunar valves 19 Jesús A. Custodio Marroquín
27. Atrioventricular (AV) Valves Atrioventricular (AV) valves lie between the atria and the ventricles R-AV valve = tricuspid valve L-AV valve = bicuspid or mitral valve AV valves prevent backflow of blood into the atria when ventricles contract 21 Jesús A. Custodio Marroquín
28. Semilunar Heart Valves Semilunar valves prevent backflow of blood into the ventricles Aortic semilunar valve lies between the left ventricle and the aorta Pulmonary semilunar valve lies between the right ventricle and pulmonary trunk Heart sounds (“lub-dup”) due to valves closing “Lub” - closing of atrioventricular valves “Dub”- closing of semilunar valves 22 Jesús A. Custodio Marroquín
30. The Heart Valves Atrioventricular valves Semilunar valves Right AV (Tricuspid) separates the right atrium from the right ventricle. Prevents backflow into atrium. Left AV (Bicuspid) separates the left atrium from the left ventricle. Prevents backflow into atrium. Pulmonary valve separates the right ventricle from the pulmonary arteries. Prevents backflow after ventricular contraction. Aortic valve separates the left ventricle from the aorta. Prevents backflow after ventricular contraction . 24 Jesús A. Custodio Marroquín
31. The Heart Valves Pulmonary semilunar valve Right AV (tricuspid) valve Aortic semilunar valve Chordai tendineae Papillary muscle Left AV (bicuspid) valve 25 Jesús A. Custodio Marroquín
32. Arterial Supply of the Heart The arterial supply of the heart is provided by the right and left coronary arteries, which arise from the ascending aorta immediately above the aortic valve. 26 Jesús A. Custodio Marroquín
33. Right coronary artery Branches Right marginal arteries (acute marginal artery) Posterior interventricular artery. (in post. IV sulcus) Sinoatrial nodal artery. Atrioventricular nodal artery. 27 Jesús A. Custodio Marroquín
34. Left coronary artery Branches Left anterior descending (LAD) or anterior interventricular artery. (lies in anterior IV sulcus) Septal branches. Diagonal branches Left marginal artery. (Obtuse marginal artery) Left circumflex artery. 28 Jesús A. Custodio Marroquín
36. Venous Drainage of the Heart Most blood from the heart wall drains into the right atrium through the coronary sinus ,which lies in the posterior part of the atrioventricular groove . It is a continuation of the great cardiac vein. It opens into the right atrium to the left of the inferior vena cava 30 Jesús A. Custodio Marroquín
38. Nerve Supply of the Heart The heart is innervated by sympathetic and parasympathetic fibers of the autonomic nervous system via the cardiac plexuses situated below the arch of the aorta. 32 Jesús A. Custodio Marroquín