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Health-related effects of
government tobacco control
policies: What's the
evidence?
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2
What’s the evidence?
Hoffman SJ, & Tan C. (2015). Overview
of systematic reviews on the health-
related effects of government tobacco
control policies. BMC Public
Health, 15(744).
http://www.healthevidence.org/view-article.aspx?a=
Poll Question #1
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Evidence
Decision
Making
inform
Why use www.healthevidence.org?
1. Saves you time
2. Relevant & current evidence
3. Transparent process
4. Supports for EIDM available
5. Easy to use
A Model for Evidence-
Informed Decision Making
National Collaborating Centre for Methods and Tools. (revised 2012). A
Model for Evidence-Informed Decision-Making in Public Health (Fact
Sheet). [http://www.nccmt.ca/pubs/FactSheet_EIDM_EN_WEB.pdf]
Stages in the process of Evidence-
Informed Public Health
National Collaborating Centre for Methods and Tools. Evidence-Informed
Public Health. [http://www.nccmt.ca/eiph/index-eng.html]
Poll Question #3
Have you heard of PICO(S) before?
1.Yes
2.No
Searchable Questions Think “PICOS”
1. Population (situation)
2. Intervention (exposure)
3. Comparison (other group)
4. Outcomes
5. Setting
How often do you use Systematic Reviews
to inform a program/services?
A.Always
B.Often
C.Sometimes
D.Never
E.I don’t know what a systematic review is
Poll Question #4
Steven J. Hoffman
Director of Global Strategy Lab
and Associate Professor of Law,
University of Ottawa
Charlie Tan
MD Candidate, Michael G.
DeGroote School of Medicine,
McMaster University
Government tobacco control policies
improve health outcomes of the general
population
A.Strongly agree
B.Agree
C.Neutral
D.Disagree
E.Strongly disagree
17
Poll Question #5
Review
Hoffman SJ, & Tan C. (2015). Overview of
systematic reviews on the health-related
effects of government tobacco control
policies. BMC Public Health, 15(744).
Importance of Review
• The global tobacco epidemic is a major public
health problem that continues to deepen
– Nearly one billion smokers worldwide in 2012
– Leading cause of preventable death
– More than 600 000 annual deaths due to secondhand
smoke (SHS) exposure
Framework Convention on Tobacco
Control (FCTC)
• International treaty introduced by the World
Health Organization (WHO) in 2005
• Aims to reduce tobacco consumption and
protect all people from tobacco exposure
through provisions that direct countries to
implement tobacco control programs
• 180 parties (as of December 2015)
MPOWER
Rationale of Review
• To take stock of the global research evidence
base about the health effects of government
tobacco control policies
• Provides policymakers with an evidence-based
resource to help with deliberations and decision-
making on setting priorities for national FCTC
implementation
Overview of Systematic Reviews
• This overview includes systematic reviews
evaluating government tobacco control policies
• Overviews of systematic reviews build on the
strengths of individual reviews and add breadth
by integrating the findings of many reviews
together
Review Focus:
• P Any individual who smokes and/or may be
affected by smoking (through SHS exposure)
• I Government tobacco control policies
• C Different interventions (e.g., clinical) or no
intervention
• O Outcome measures relating to tobacco use,
SHS exposure and primary health outcomes
Literature Search
• Relevant reviews were identified through:
– Electronic databases
• Health Evidence (HE), Health Systems Evidence (HSE), Rx
for Change (RC), Cochrane Database of Systematic
Reviews (CDSR), Database of Abstracts of Reviews of
Effects (DARE)
– References of other overviews of systematic reviews
– Monthly updates
• HE, HSE, Quebec Public Health Research Network
– Two tobacco control experts
Study Selection
• Titles and abstracts screening
• Full text review
• Two independent reviewers, with conflicts
resolved through discussion
Exclusion Criteria
• Reviews that did not follow a systematic methodology
• Other overviews of systematic reviews
• Reviews evaluating clinical interventions
• Reviews evaluating multicomponent tobacco control
programs if effects of individual interventions were not
independently studied or could not be differentiated
• Reviews evaluating recall of media campaigns and
perceptions of smoking as outcome measures
• No exclusions on the basis of language
Data Extraction
• Following variables were extracted from
the reviews into a summary table:
– Number of studies included
– Year of last search
– Key findings from review
Risk of Bias
• Quality ratings given to each review by their
source databases were extracted
– HE
• Independent quality assessment tool specific for public
health intervention literature
– HSE and RC
• AMSTAR
– CDSR and DARE
• No numerical quality rating; quality assessment was
independently performed using the AMSTAR tool
Review Prioritization
• In order to focus on most recent and
accurate evidence, we prioritized:
– Strong and moderate quality reviews (based
on HE or AMSTAR tools); and
– Reviews published since 2000
Findings
• MPOWER components were used as organizing
framework, with an additional FCTC provision
(Restrict sales to minors)
– No reviews found for Monitor tobacco use and
prevention policies
• Outcomes grouped into seven categories:
– Tobacco consumption, smoking prevalence, smoking
cessation, smoking initiation, SHS exposure, medical
conditions, hospitalization
Findings
Protect people from tobacco smoke
Number of Reviews 12
Quality 3 strong, 8 moderate, 1 moderate
(HE)/strong (HSE)
Findings • 8 reviews on smoking behaviour; 6
reported beneficial effects
• 3 reviews on SHS; all reported
reductions in SHS exposure
• 6 reviews on health outcomes; all
reported reductions in adverse effects
Findings
Offer help to quit tobacco use
Number of Reviews 12
Quality 8 strong, 4 moderate
Findings • 2 reviews on financial assistance for
smokers; both reported beneficial
effects on smoking behaviour
• 8 reviews on incentives and
competitions for smokers; 4 reported
beneficial effects on smoking behaviour
• 3 reviews on provider-directed financial
interventions; all reported no effect on
smoking behaviour
Findings
Warn about the dangers of tobacco
Number of Reviews 9
Quality 4 strong, 5 moderate
Findings • 3 reviews on health warning labels or
plain packaging on tobacco products; 2
reported beneficial effects on smoking
behaviour
• 7 reviews on mass media campaigns; 4
reported beneficial effects on smoking
behaviour (as part of multicomponent
tobacco control programs)
Findings
Enforce bans on tobacco advertising, promotion
and sponsorship
Number of Reviews 4
Quality 4 moderate
Findings • No reviews reported beneficial effects
on smoking behaviour
• Large amount of evidence linking
advertisements and tobacco use
• Individual studies suggest scope
and enforcement are critical
Findings
Raise taxes on tobacco
Number of Reviews 6
Quality 1 strong, 5 moderate
Findings • 5 reported beneficial effects on
smoking behaviour
• Negative price elasticities of
demand for increases in cigarette
prices and smoking behaviour
Findings
Restrict sales to minors
Number of Reviews 5
Quality 5 moderate
Findings • Inconsistent evidence on effects on
smoking behaviour
• If effective, appear to depend on
robust enforcement
Principal Findings
• Strongest evidence for smoking bans and price
increases of tobacco products
• Positive results also found for mass media
campaigns (as part of multicomponent
programs) and cigarette packaging interventions
• Financial assistance reducing the costs of
smoking cessation interventions and financial
incentives may be effective strategies
• Limited evidence found for advertising
restrictions and youth access restrictions
Strengths and Limitations
• Strengths
– Synthesis of large number of studies (over 1150)
– Systematic and transparent search protocol
– Reviews prioritized by quality and publication date
• Limitations
– Search did not include unpublished reviews
– Reviews in other disciplines may have been excluded
or have low quality ratings
– Loss of study intricacies and details
– Reviews on multicomponent interventions excluded
Future Directions
• Effectiveness of smoke-free policies and tobacco price
increases is well established
• Further evaluations of the remaining interventions
• Studies of the various factors that can influence
effectiveness and feasibility (cost, local context, political
barriers and implementation strategies)
• Studies of the synergistic effects of multicomponent
programs and which which combinations of policies are
most effective and/or feasible
• “Endgame proposals” to eliminate tobacco use
Overall Summary and Implications
• Countries should ideally implement policies
concurrently to develop multicomponent programs
• Regulations that ban smoking and increase
tobacco product prices should be prioritized if
needed when resources are constrained
• Other FCTC provisions can further strengthen and
work synergistically with these priority policies
Government tobacco control policies
improve health outcomes of the general
population
A.Strongly agree
B.Agree
C.Neutral
D.Disagree
E.Strongly disagree
43
Poll Question #6
Poll Question #7
Do you agree with the findings of this
review?
A.Strongly agree
B.Agree
C.Neutral
D.Disagree
E.Strongly disagree
Questions?
A Model for Evidence-
Informed Decision Making
National Collaborating Centre for Methods and Tools. (revised 2012). A
Model for Evidence-Informed Decision-Making in Public Health (Fact
Sheet). [http://www.nccmt.ca/pubs/FactSheet_EIDM_EN_WEB.pdf]
47
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Health-related effects of government tobacco control policies: What's the evidence?

  • 1. Welcome! Health-related effects of government tobacco control policies: What's the evidence? You will be placed on hold until the webinar begins. The webinar will begin shortly, please remain on the line.
  • 2. After Today • The PowerPoint presentation and audio recording will be made available • These resources are available at: – PowerPoint: http:// www.slideshare.net/HealthEvidence – Audio Recording: https://www.youtube.com/user/healthevidence/vide 2
  • 3. What’s the evidence? Hoffman SJ, & Tan C. (2015). Overview of systematic reviews on the health- related effects of government tobacco control policies. BMC Public Health, 15(744). http://www.healthevidence.org/view-article.aspx?a=
  • 4. Poll Question #1 What sector are you from? 1. Public Health Practitioner 2. Health Practitioner (Other) 3. Education 4. Research 5. Provincial/Territorial/Government/Ministry 6. Municipality 7. Policy Analyst (NGO, etc.) 8. Other 4
  • 5. • Use Q&A or CHAT to post comments / questions during the webinar – ‘Send’ questions to All Panelists (not privately to ‘Host’) • Connection issues – Recommend using a wired Internet connection (vs. wireless), • WebEx 24/7 help line – 1-866-229-3239 Participant Side Panel in WebEx Housekeeping
  • 6. Housekeeping (cont’d) • Audio – Listen through your speakers – Go to ‘Communicate > Audio Connection’ • WebEx 24/7 help line – 1-866-229-3239
  • 7. Poll Question #2 How many people are watching today’s session with you? 1.Just me 2.2-3 3.4-5 4.Over 5
  • 8. The Health Evidence Team Maureen Dobbins Scientific Director Heather Husson Manager Susannah Watson Project Coordinator Robyn Traynor Publications Consultant Students: Emily Belita (PhD candidate) Jennifer Yost Assistant Professor Olivia Marquez Research Coordinator Kristin Read Research Coordinator Yaso Gowrinathan Information Liaison Emily Sully Research Assistant Bethel Woldemichael Research Assistant Liz Kamler Research Assistant Zhi (Vivian) Chen Research Assistant
  • 10. Why use www.healthevidence.org? 1. Saves you time 2. Relevant & current evidence 3. Transparent process 4. Supports for EIDM available 5. Easy to use
  • 11. A Model for Evidence- Informed Decision Making National Collaborating Centre for Methods and Tools. (revised 2012). A Model for Evidence-Informed Decision-Making in Public Health (Fact Sheet). [http://www.nccmt.ca/pubs/FactSheet_EIDM_EN_WEB.pdf]
  • 12. Stages in the process of Evidence- Informed Public Health National Collaborating Centre for Methods and Tools. Evidence-Informed Public Health. [http://www.nccmt.ca/eiph/index-eng.html]
  • 13. Poll Question #3 Have you heard of PICO(S) before? 1.Yes 2.No
  • 14. Searchable Questions Think “PICOS” 1. Population (situation) 2. Intervention (exposure) 3. Comparison (other group) 4. Outcomes 5. Setting
  • 15. How often do you use Systematic Reviews to inform a program/services? A.Always B.Often C.Sometimes D.Never E.I don’t know what a systematic review is Poll Question #4
  • 16. Steven J. Hoffman Director of Global Strategy Lab and Associate Professor of Law, University of Ottawa Charlie Tan MD Candidate, Michael G. DeGroote School of Medicine, McMaster University
  • 17. Government tobacco control policies improve health outcomes of the general population A.Strongly agree B.Agree C.Neutral D.Disagree E.Strongly disagree 17 Poll Question #5
  • 18. Review Hoffman SJ, & Tan C. (2015). Overview of systematic reviews on the health-related effects of government tobacco control policies. BMC Public Health, 15(744).
  • 19. Importance of Review • The global tobacco epidemic is a major public health problem that continues to deepen – Nearly one billion smokers worldwide in 2012 – Leading cause of preventable death – More than 600 000 annual deaths due to secondhand smoke (SHS) exposure
  • 20. Framework Convention on Tobacco Control (FCTC) • International treaty introduced by the World Health Organization (WHO) in 2005 • Aims to reduce tobacco consumption and protect all people from tobacco exposure through provisions that direct countries to implement tobacco control programs • 180 parties (as of December 2015)
  • 22. Rationale of Review • To take stock of the global research evidence base about the health effects of government tobacco control policies • Provides policymakers with an evidence-based resource to help with deliberations and decision- making on setting priorities for national FCTC implementation
  • 23. Overview of Systematic Reviews • This overview includes systematic reviews evaluating government tobacco control policies • Overviews of systematic reviews build on the strengths of individual reviews and add breadth by integrating the findings of many reviews together
  • 24. Review Focus: • P Any individual who smokes and/or may be affected by smoking (through SHS exposure) • I Government tobacco control policies • C Different interventions (e.g., clinical) or no intervention • O Outcome measures relating to tobacco use, SHS exposure and primary health outcomes
  • 25. Literature Search • Relevant reviews were identified through: – Electronic databases • Health Evidence (HE), Health Systems Evidence (HSE), Rx for Change (RC), Cochrane Database of Systematic Reviews (CDSR), Database of Abstracts of Reviews of Effects (DARE) – References of other overviews of systematic reviews – Monthly updates • HE, HSE, Quebec Public Health Research Network – Two tobacco control experts
  • 26. Study Selection • Titles and abstracts screening • Full text review • Two independent reviewers, with conflicts resolved through discussion
  • 27. Exclusion Criteria • Reviews that did not follow a systematic methodology • Other overviews of systematic reviews • Reviews evaluating clinical interventions • Reviews evaluating multicomponent tobacco control programs if effects of individual interventions were not independently studied or could not be differentiated • Reviews evaluating recall of media campaigns and perceptions of smoking as outcome measures • No exclusions on the basis of language
  • 28. Data Extraction • Following variables were extracted from the reviews into a summary table: – Number of studies included – Year of last search – Key findings from review
  • 29. Risk of Bias • Quality ratings given to each review by their source databases were extracted – HE • Independent quality assessment tool specific for public health intervention literature – HSE and RC • AMSTAR – CDSR and DARE • No numerical quality rating; quality assessment was independently performed using the AMSTAR tool
  • 30. Review Prioritization • In order to focus on most recent and accurate evidence, we prioritized: – Strong and moderate quality reviews (based on HE or AMSTAR tools); and – Reviews published since 2000
  • 31.
  • 32. Findings • MPOWER components were used as organizing framework, with an additional FCTC provision (Restrict sales to minors) – No reviews found for Monitor tobacco use and prevention policies • Outcomes grouped into seven categories: – Tobacco consumption, smoking prevalence, smoking cessation, smoking initiation, SHS exposure, medical conditions, hospitalization
  • 33. Findings Protect people from tobacco smoke Number of Reviews 12 Quality 3 strong, 8 moderate, 1 moderate (HE)/strong (HSE) Findings • 8 reviews on smoking behaviour; 6 reported beneficial effects • 3 reviews on SHS; all reported reductions in SHS exposure • 6 reviews on health outcomes; all reported reductions in adverse effects
  • 34. Findings Offer help to quit tobacco use Number of Reviews 12 Quality 8 strong, 4 moderate Findings • 2 reviews on financial assistance for smokers; both reported beneficial effects on smoking behaviour • 8 reviews on incentives and competitions for smokers; 4 reported beneficial effects on smoking behaviour • 3 reviews on provider-directed financial interventions; all reported no effect on smoking behaviour
  • 35. Findings Warn about the dangers of tobacco Number of Reviews 9 Quality 4 strong, 5 moderate Findings • 3 reviews on health warning labels or plain packaging on tobacco products; 2 reported beneficial effects on smoking behaviour • 7 reviews on mass media campaigns; 4 reported beneficial effects on smoking behaviour (as part of multicomponent tobacco control programs)
  • 36. Findings Enforce bans on tobacco advertising, promotion and sponsorship Number of Reviews 4 Quality 4 moderate Findings • No reviews reported beneficial effects on smoking behaviour • Large amount of evidence linking advertisements and tobacco use • Individual studies suggest scope and enforcement are critical
  • 37. Findings Raise taxes on tobacco Number of Reviews 6 Quality 1 strong, 5 moderate Findings • 5 reported beneficial effects on smoking behaviour • Negative price elasticities of demand for increases in cigarette prices and smoking behaviour
  • 38. Findings Restrict sales to minors Number of Reviews 5 Quality 5 moderate Findings • Inconsistent evidence on effects on smoking behaviour • If effective, appear to depend on robust enforcement
  • 39. Principal Findings • Strongest evidence for smoking bans and price increases of tobacco products • Positive results also found for mass media campaigns (as part of multicomponent programs) and cigarette packaging interventions • Financial assistance reducing the costs of smoking cessation interventions and financial incentives may be effective strategies • Limited evidence found for advertising restrictions and youth access restrictions
  • 40. Strengths and Limitations • Strengths – Synthesis of large number of studies (over 1150) – Systematic and transparent search protocol – Reviews prioritized by quality and publication date • Limitations – Search did not include unpublished reviews – Reviews in other disciplines may have been excluded or have low quality ratings – Loss of study intricacies and details – Reviews on multicomponent interventions excluded
  • 41. Future Directions • Effectiveness of smoke-free policies and tobacco price increases is well established • Further evaluations of the remaining interventions • Studies of the various factors that can influence effectiveness and feasibility (cost, local context, political barriers and implementation strategies) • Studies of the synergistic effects of multicomponent programs and which which combinations of policies are most effective and/or feasible • “Endgame proposals” to eliminate tobacco use
  • 42. Overall Summary and Implications • Countries should ideally implement policies concurrently to develop multicomponent programs • Regulations that ban smoking and increase tobacco product prices should be prioritized if needed when resources are constrained • Other FCTC provisions can further strengthen and work synergistically with these priority policies
  • 43. Government tobacco control policies improve health outcomes of the general population A.Strongly agree B.Agree C.Neutral D.Disagree E.Strongly disagree 43 Poll Question #6
  • 44. Poll Question #7 Do you agree with the findings of this review? A.Strongly agree B.Agree C.Neutral D.Disagree E.Strongly disagree
  • 46. A Model for Evidence- Informed Decision Making National Collaborating Centre for Methods and Tools. (revised 2012). A Model for Evidence-Informed Decision-Making in Public Health (Fact Sheet). [http://www.nccmt.ca/pubs/FactSheet_EIDM_EN_WEB.pdf]
  • 47. 47 Supporting awareness and uptake of cancer prevention knowledge in practice Funded by the Canadian Institutes of Health Research Announcing: Implementation of a research project to build capacity among Canadian public health professionals to use research evidence in program planning decisions. Timeline: 18 months (Fall’15 to Spring’17) Intervention: Receive concise actionable messages based on high-quality systematic review evidence via: Twitter, webinars, and/or tailored email messages. Participants will be surveyed at baseline and follow-up. Now recruiting: Individual public health professionals across Canada working in the areas of: - Tobacco/Alcohol use - Sun safety - Healthy eating - Physical activity More info: Click here http://kt.healthevidence.org to access the Participant Information Form (Consent). If you decide to participate, you will have the option to continue to a 20 min online survey to begin your participation. Complete the survey for a chance to win an iPad Air 2 64GB! For more information, contact Research Coordinator, Olivia Marquez at marqueos@mcmaster.ca or 905-525-9140 ext. 20464
  • 48. What can I do now? Visit the website; a repository of over 4,400 quality-rated systematic reviews related to the effectiveness of public health interventions. Health Evidence™ is FREE to use. Register to receive monthly tailored registry updates AND monthly newsletter to keep you up to date on upcoming events and public health news. Tell your colleagues about Health Evidence™: helping you use best evidence to inform public health practice, program planning, and policy decisions! Follow us @Health Evidence on Twitter and receive daily public health review- related Tweets, receive information about our monthly webinars, as well as announcements and events relevant to public health. Encourage your organization to use Health Evidence™ to search for and apply quality-rated review level evidence to inform program planning and policy decisions. Contact us to suggest topics or provide feedback. info@healthevidence.org
  • 49. Thank you! Contact us: info@healthevidence.org For a copy of the presentation please visit: http://www.healthevidence.org/webinars.aspx Login with your Health Evidence username and password, or register if you aren’t a member yet.

Editor's Notes

  1. Poll question #4
  2. here’s a look at the team many involved in the work to keep HE current and maintained
  3. Health Evidence launched in 2005 comprehensive registry of reviews evaluating the effectiveness of public health and health promotion interventions provide over 90,000 visitors per year access to over 4,300 quality-rated systematic reviews links to full text, plain language summaries, and podcasts (where available) One of main goals of Health Evidence, in addition to making evidence re: effectiveness of PH interventions more accessible, is to make it easier for professionals to use evidence in decision making
  4. Model for Evidence-Informed decision making in PH consists of 5 components visible in this diagram Traditionally public health practitioners and decision makers do consider evidence about community health issues and local context, existing resources, and community and political climate in making decisions about programs and policies however, it has become apparent that a considering evidence about research may be more challenging As such the Health Evidence webinar series is designed to identify research evidence relevant to public health decisions
  5. The EIPH wheel illustrates the steps involved in evidence-informed practice The wheel is a guide for practitioners and decision makers to determine how to address a particular issue by systematically incorporating research evidence in the decision making process There are 7 steps in the EIPH process that starts with: Clearly defining the problem; Searching the research literature; Appraising the evidence you find; Synthesizing or summarizing the research on your issue; Adapting and interpreting the findings to your local context; Implementing the evidence or appropriate intervention; and Evaluating your implementation efforts. We will hear today about how (presenter) has worked through the first 4 steps, in order to help with the decision makers with the remainder of the 7 steps
  6. Poll question #4
  7. Steven Hoffman – also has courtesy appts as associate professor of public & international affairs at the University of Ottawa and associate professor of clinical epidemiology & biostatistics at McMaster University, and adjunct associate faculty with McMaster Health Forum, and adjunct associate professor of global health & population at Harvard University
  8. The global tobacco epidemic is a major public health problem that continues to deepen, with nearly 1 billion smokers worldwide in 2012 [1]. It is the leading cause of preventable death, resulting in approximately 6 million unnecessary deaths per year [2, 3]. Cigarettes will kill half their current users through conditions such as cardiovascular disease, respiratory conditions and cancers, and mortality from smoking is expected to increase to an estimated 8 million people per year by 2030 [3]. Secondhand smoke (SHS) is a significant concern as well: more than 600,000 of the total annual deaths from smoking are due to SHS exposure [2].
  9. The year 2015 marks the tenth anniversary since the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) came into force, the first international treaty specially adopted through WHO. This instrument aims to reduce tobacco consumption and protect all people from tobacco exposure through provisions that direct countries to implement tobacco control programs [4]. The 180 parties to the FCTC (as of May 2015) are all mandated to take action [6]. However, the bi-annual reports that ratifying countries must submit show uneven progress [7].
  10. To guide countries in this process, WHO introduced the six MPOWER measures (Table 1), each of which corresponds to one or more FCTC provisions [5].
  11. The aim of this systematic overview of systematic reviews is to take stock of the global research evidence base in this decennial year about the likely health effects of different government tobacco control policies. This provides policymakers with an evidence-based resource to help with policy deliberations and decision-making on setting priorities for national FCTC implementation [8]. Systematic reviews aim to identify, assess and synthesize all available primary evidence on a research question, and use an objective, optimized and structured methodology to maximize transparency and minimize bias. Overviews of systematic reviews build on the strengths of individual reviews and add breadth by integrating the findings of many reviews together.
  12. Systematic reviews aim to identify, assess and synthesize all available primary evidence on a research question, and use an objective, optimized and structured methodology to maximize transparency and minimize bias. Overviews of systematic reviews build on the strengths of individual reviews and add breadth by integrating the findings of many reviews together.
  13. Outcome measures relating to tobacco use, SHS exposure and primary health outcomes were considered. Tobacco use outcomes include smoking prevalence, quantity of cigarettes consumed, smoking cessation and smoking initiation. SHS exposure outcomes include both self-reported and biomarker-validated measures of exposure.
  14. Relevant systematic reviews were identified through systematic searches of the electronic databases Health Evidence for research on public health and health promotion, Health Systems Evidence for research on health systems, Rx for Change for research on behaviour-change interventions, Cochrane Database of Systematic Reviews for research on healthcare and health policy, and Database of Abstracts of Reviews of Effects for research on healthcare and health services delivery, published up to March 2014. These databases are continuously updated and together represent the leading repositories of health-related systematic reviews. For Health Evidence, the search term “tobacco use” was entered; for other databases, “tobacco” was entered. This search strategy was designed to be very broad and capture as many systematic reviews related to tobacco use as possible. Relevant reviews in monthly updates from Health Evidence, Health Systems Evidence and the Quebec Public Health Research Network were included as well up to August 2014. Two tobacco control experts known to the authors were also consulted to identify any reviews missed by the systematic searches. An additional targeted search for systematic reviews on mass media campaigns was conducted in May 2015 in response to peer review feedback.
  15. Titles and abstracts were assessed to identify reviews for inclusion. The full texts were then read to confirm inclusion.
  16. The present overview includes systematic reviews evaluating government tobacco control policies. Reviews that did not follow a systematic methodology and other overviews of systematic reviews were not included; the latter’s references were scanned to identify reviews for inclusion. The MPOWER components were used as an organizing framework to classify the interventions. Clinical interventions, such as pharmacologic therapy and counselling services, were not included. Reviews on multicomponent programs were excluded if the effects of individual interventions were not independently studied or could not be differentiated. Health outcomes include hospital admissions and risk of any adverse medical event. Measures that did not directly assess change in smokers, such as recall of media campaigns and perceptions of smoking, were not included. Reviews were not excluded on the basis of language.
  17. The following data from selected studies were abstracted into a summary table: number of studies included, year of last search and key findings. The quality ratings given to each review by their source databases were extracted as well.
  18. The quality ratings given to each review by their source databases were extracted as well. Health Evidence uses an independent quality assessment tool specific for public health intervention literature [9]. Total scores can range from 0 to 10, based on which a quality rating is assigned: “strong” (8 to 10), “moderate” (5 to 7) or “weak” (4 or less). Health Systems Evidence and Rx for Change use the AMSTAR tool, which evaluates the quality of systematic reviews and meta-analyses by 11 quality criteria [10–12]. Reviews with scores from 9 to 11 are rated as “high,” from 5 to 8 as “medium,” and from 0 to 4 as “low.” For this overview, the “strong,” “moderate” and “weak” terminology was used for AMSTAR to maintain consistency with Health Evidence. Cochrane Database of Systematic Reviews does not provide ratings and Database of Abstracts of Reviews of Effects offers a descriptive quality assessment [13]. A quality assessment was independently performed using the AMSTAR tool for reviews without a numerical quality rating. Strong and moderate quality reviews published since 2000 were prioritized in the qualitative synthesis.
  19. Six hundred and twelve reviews were identified through the search strategy. Screening titles and abstracts yielded 67 reviews that possibly met the inclusion criteria. Two reviewers screened the full-text of reviews and confirmed 45 met the inclusion criteria. Any conflicts were resolved by discussion between the two reviewers and a third reviewer was consulted when required. Four additional reviews for inclusion were identified from monthly updates, nine were identified by tobacco control experts and one was identified from the targeted search for reviews on mass media campaigns. In total, 59 reviews were included that together summarized over 1150 primary studies (see Fig. 1) [14–72].1 The 22 reviews excluded after full-text screening either evaluated excluded outcome measures (n = 1) [73], were overviews of systematic reviews (n = 3) [74–76], did not follow a systematic methodology (n = 1) [77], only reported results of multicomponent programs (n = 4) [78–81], did not adequately describe what interventions were evaluated (n = 2) [82, 83], or were not relevant for assessing government tobacco control policies (n = 11) [84–94]. Findings from the 38 reviews that were either strong or moderate quality and published since 2000 are presented here (see Fig. 2) [14–51].
  20. Twelve reviews summarize the health-related effects of smoking bans and restrictions in public spaces, workplaces or residences. Three are strong in quality [14–16], eight are moderate [17–24] and one is rated as moderate by HE and as strong by HSE [25]. Overall, most of the eight reviews on smoking behaviour reported reductions in smoking prevalence and cigarette consumption and increases in smoking cessation [14, 15, 17–19, 21, 24, 25]. Hopkins et al. found that workplace smoke-free policies lead to an absolute reduction in smoking prevalence of 3.4 % (interquartile range (IQR) = −6.3 to −1.4), reduced cigarette consumption by 2.2 cigarettes per day (IQR = −1.7 to −3.3), increased quit attempts by 4.1 % (IQR = −0.7 to 6.8) and increased successful cessation by 6.4 % (IQR = 2.0 to 9.7) [15]. Three reviews found inconsistent evidence for smoking prevalence or cessation, but reported improvements in other smoking behaviour outcomes [14, 18, 21]. Thomas et al. looked at the effect of smoking bans on social inequalities in smoking [19] and Kohler and Minkner reviewed the conditions under which state smoking bans are effective [24], but neither assessed their overall efficacy. Three reviews investigating SHS all reported reductions in SHS exposure with smoke-free policies, in both adults and children and across various settings including workplaces, public spaces and hospitality establishments [14, 21, 25]. Similarly, all six reviews investigating primary health outcomes found decreases in adverse events [16, 20–23, 25]. Tan and Glantz looked at hospital admissions data and found a reduced risk of admission for coronary events (relative risk (RR) = 0.85, 95 % confidence interval (CI) = 0.82 to 0.88), other heart diseases (RR = 0.61, 95 % CI = 0.44 to 0.85), cerebrovascular accidents (RR = 0.81, 95 % CI = 0.70 to 0.94) and respiratory diseases (RR = 0.76, 95 % CI = 0.68 to 0.85) with smoke-free policies [22]. The reductions were greatest with comprehensive policies that banned smoking in workplaces, restaurants and bars. Therefore, there is very strong evidence that smoke-free legislation reduces smoking behaviour, exposure to SHS and adverse health outcomes.
  21. Twelve reviews present research evidence on the effect of financial assistance or incentives for smokers to quit smoking and for healthcare professionals to provide smoking cessation interventions.2 Eight are strong in quality [14, 26–32] and four are moderate [33–36]. Financial interventions appear to have different effects depending on whether they are incentives to quit smoking or assistance to lower the cost of cessation therapies, and whether they target smokers or healthcare providers. Two reviews investigated smoker-directed financial assistance and found increased uptake of cessation therapies and greater levels of smoking cessation [14, 28]. The effect of incentives and competitions for smokers is less clear, with four reviews reporting increased cessation [30–32, 35] and four reviews finding an unclear or no effect [26, 27, 29, 33]. Giles et al. [31] and Cahill and Lancaster [32] found that smokers offered incentives were 2.48 times (95 % CI = 1.77 to 3.46) and 1.60 times (95 % CI = 1.12 to 2.30) more likely to quit smoking, respectively. In pregnant women, Likis et al. reported that financial incentives increased smoking cessation and were the most important component of multicomponent programs that promote cessation [30]. Conversely, Cahill and Perera found no effect of incentives on long-term quit rates [27], and a separate review by the same authors estimated that community “quit-and-win” contests lead to fewer than one in 500 smokers quitting smoking [26]. The three reviews that looked at provider-directed financial interventions found no effect on smoking abstinence and prevalence in patients [28, 34, 36]. Financial interventions may thus be more effective for smoking cessation when they are targeted to make cessation therapies more affordable, but incentivizing quitting may be effective as well. They do not appear to influence smoking behaviour when directed at healthcare professionals.
  22. Three reviews contained evidence on the effects of health warning labels or plain packaging on tobacco products. All three are moderate in quality [19, 21, 37]. Two reviews found health warning labels decrease smoking behaviour, reporting reductions in tobacco use and increases in motivation to quit, quitting likelihood and likelihood of abstinence after quitting [21, 37]. Thomas et al. found no effect [19]. Among seven reviews assessing mass media campaigns, four are strong in quality [14, 38–40] and three are moderate [21, 41, 42]. Five reviews looked at media campaigns as part of comprehensive tobacco control programs and four reported reductions in smoking behaviour [14, 21, 38, 41]. Bala et al. showed inconsistent effects and raised concerns about the quality of the evidence [40]. An update to this review found strong evidence that mass media campaigns, within the context of multicomponent programs, promote cessation and reduce smoking prevalence [41]. This updated review identified several features of effective campaigns: wide population reach, high intensity, long duration, use of television and messages on the negative health effects of smoking [41]. The remaining systematic reviews focused on mass media campaigns in subpopulations. Guillaumier et al. found insufficient evidence for their effect on smokers of low socioeconomic status [42], while Brinn et al. [39] reported inconsistent evidence for their effect on young people. Therefore, the evidence suggests that interventions cautioning people about tobacco’s harms may be effective strategies, with mass media campaigns being potentially important parts of multicomponent programs.
  23. Four reviews present research evidence on the health-related effects of tobacco advertising bans and restrictions, all of which are moderate in quality [19, 21, 43, 44]. None of the reviews found clear reductions in smoking behaviour, with Quentin et al. reporting inconsistent effects [43] and Capella et al. showing no reduction in cigarette consumption [44]. Although Mozaffarian et al. did not report any direct effects, this review postulated that advertising restrictions should decrease smoking behaviour based on the well-established association between advertisements and tobacco use [21]. Indeed, individual studies have demonstrated that tobacco marketing and cigarette use in movies alter adolescents’ attitudes and susceptibilities to smoking, which in turn places them at risk of initiating cigarette use and continuing this behaviour into adulthood [95–99]. Although systematic reviews have not conclusively shown that banning tobacco marketing is an effective tobacco control measure, substantial evidence exists on the harmful consequences of unregulated advertising on smoking behaviour. In addition, there are individual studies that support the effectiveness of these interventions. Saffer and Chaloupka looked at 22 OECD countries and showed that comprehensive advertising bans reduce tobacco consumption, but that limited advertising bans—where other avenues of promotion are still available to companies—do not reduce tobacco consumption [100]. An analogous study by Blecher that included the OECD countries as well as 30 developing countries had similar findings [101]. A sub-analysis of the developing countries showed that both comprehensive and limited bans reduced smoking in these countries, with comprehensive bans having greater effects [101]. The scope of advertising restrictions and how they are enforced may therefore be critical factors in their effectiveness.
  24. Among the six reviews evaluating tobacco price increases, one is high in quality [14] and five are moderate [19, 21, 45–47]. All but one of the reviews found that increasing the price of tobacco reduces smoking behaviour, with decreases in cigarette consumption and smoking prevalence and increases in smoking cessation. Hopkins et al. combined seven studies that estimated price elasticities of demand and found that every 10 % increase in cigarette prices decreased smoking prevalence and cigarette consumption by 3.7 and 2.3 %, respectively [14]. Price increases appear to be most effective among adolescents, young adults and persons of low socioeconomic status [19, 45, 46]. Rice et al. reported negative price elasticities for smoking participation, prevalence, consumption and initiation, and greater smoking cessation in youths with price increases [46]. However, Guindon found inconclusive results on the effect of tobacco price increases on smoking initiation [47]. Overall the evidence indicates increasing the price of tobacco products is a very important intervention for tobacco control.
  25. Five reviews summarize the health-related effects of restricting youth access to tobacco products, all of which are moderate in quality [19, 48–51]. This intervention is not part of MPOWER but is promoted in the FCTC under Article 16 (“prohibiting sales to and by minors”). Across the systematic reviews there was no consistent effect found for youth access interventions on smoking behaviour. Fichtenberg and Glantz showed that such restrictions do not reduce smoking prevalence among teens, even with high compliance among cigarette merchants [48]. However, DiFranza reported that banning the sale of tobacco products to minors is effective in decreasing youth smoking, but only if the restrictions are strongly enforced [51]. The three remaining reviews found inconsistent evidence [19, 49, 50]. The literature on youth access interventions is thus inconclusive; restrictions, if they are effective, appear to depend on robust enforcement.
  26. This systematic overview of systematic reviews summarizes the research evidence on the likely health-related effects of government tobacco control policies promoted in the FCTC, identifying gaps in the literature and providing a framework for policy deliberations and future research. It includes 59 systematic reviews, encompassing more than 1150 individual studies. Among the government tobacco control policies identified, protecting people from tobacco smoke through smoking bans and price increases of tobacco products have the strongest evidence of effectiveness. Smoke-free policies were consistently associated with reductions in smoking behaviour, SHS exposure and adverse health outcomes. Their success has been demonstrated in diverse settings. Robust evidence was similarly found for raising tobacco prices, such as through taxation, with decreases in smoking behaviour found by five reviews. The cumulative evidence from this overview suggests that smoke-free policies and tobacco taxation may be the two most important interventions promoted by the FCTC and should be prioritized by governments when developing their tobacco control programs. Positive results were also found for warning people about the dangers of tobacco through mass media campaigns and cigarette packaging interventions, with the former likely being integral parts of multicomponent programs. Financial assistance reducing the costs of smoking cessation interventions and financial incentives may be effective strategies; the effect of provider-directed interventions is less clear. Limited evidence was found for advertising restrictions, but evidence on how advertisements influence smoking behaviour, the substantial investments that cigarette companies have made to promote their products and individual studies demonstrating their effectiveness all suggest these interventions remain important. No reviews were identified for monitoring tobacco use and prevention policies, indicating a need for research syntheses on their effectiveness.
  27. This overview has several methodological strengths. First, prioritizing systematic reviews allowed a huge body of research evidence to be synthesized—over 1150 studies—covering a wide variety of interventions, outcomes, conditions and populations in a single analysis. Second, a systematic and transparent search protocol was implemented, minimizing bias while ensuring that as many systematic reviews evaluating government tobacco control policies as possible were identified and assessed for inclusion. Third, the quality of each systematic review was considered, with quality ratings either extracted from source databases or independently scored. These quality ratings were then used, along with the date of publication, to prioritize included reviews, maximizing confidence in the resulting analyses as a good starting point for decision-making. This overview also has several limitations. First, searches were restricted to the five leading databases of systematic reviews; unpublished reviews will have been missed. Furthermore, many disciplines have different approaches to literature reviews that place less emphasis on describing the search strategy and inclusion/exclusion criteria. As such, some excellent comprehensive reviews may have been excluded by the databases or have low quality ratings [67, 103, 105]. Second, the intricacies and details of each individual study are invariably lost when integrating findings from over 1150 primary sources. Third, evaluations of multicomponent policies were excluded, limiting this overview to summarizing the impact of interventions when used in isolation.
  28. Static version