Granthi (Cyst) are soft, fluid-filled swellings lined by epithelium or endothelium. They are classified based on etiology and location. Common types include vataj, pittaj, and kaphaj cysts related to the doshas, as well as medoj, siraj and dermoid cysts. Symptoms depend on location and contents of the cyst. Treatment typically involves complete surgical excision to prevent complications like infection.
LN Ayurved College & Hospital, Kolar Road, Bhopal professor of Panchakarma and Head of the department Dr K Shiva Rama Prasad has delivered a Guest lecture on the Importance and Standard procedures of Raktamokshana at Institute of Post Graduate Ayurvedic Education & Research under Dept. of Health & Family Welfare, Government of West Bengal on 18th November 2019.
Kayachikitsa IMP Schlok – Part 7 - PPT
By Prof. Dr. R. R. Deshpande
• This PPT has following features –
• Imp Contents – Vata Vyadhi Chikitsa,Gudagat-Aamashayagat –Pakwashayagat – Siragat, Asthi Majjagat –Vata ,Ardit or Facial Palsy ,Pakshaghat or Hemiplegia, Grudhrasi or Sciatica ,Pashangardabha or Mumps, Kadar or corn ,Indralupta or Alopecia areata ,Darunak or Dandruff, Niruddha Prakash or Phimosis ,Unmad or Hysteria ,Apasmar or Epilepsy ,
• Visit – www.ayurvedicfriend.com
Phone – 922 68 10 630
The Research topics and reseaech areas has been explained in ail, which are helpful for Undergraduates to get the research grants, PG Scholars and Ph.D Scholars to select theirs research topics..
Fracture & dislocation is well described in Ayurveda. Sushruta Samhita have a separate chapter for bhagna etiology, features, types, prognosis, Management by name of Bhagna-Kandabhagna-Sandhimukta. The basics principles and management of fracture are accurate as per modern orthopedics.
this is an ppt presentation by dr.b.arun kumar, who is working as a lecturer in MNR ayurvedic medical college, sangareddy, near hyderabad. in this presentation i given all details of virechana karma.
A practical understanding of Ksheera Vasthi. Some of the commonly practiced Ksheera Vasthi's are discussed here. KB is brumhana shodhana basti. KB can be prepared with varied Ksheerapaka for better effect in varied conditions based on yukti. It is widely used and effective in Asthivaha srotho vikara.
LN Ayurved College & Hospital, Kolar Road, Bhopal professor of Panchakarma and Head of the department Dr K Shiva Rama Prasad has delivered a Guest lecture on the Importance and Standard procedures of Raktamokshana at Institute of Post Graduate Ayurvedic Education & Research under Dept. of Health & Family Welfare, Government of West Bengal on 18th November 2019.
Kayachikitsa IMP Schlok – Part 7 - PPT
By Prof. Dr. R. R. Deshpande
• This PPT has following features –
• Imp Contents – Vata Vyadhi Chikitsa,Gudagat-Aamashayagat –Pakwashayagat – Siragat, Asthi Majjagat –Vata ,Ardit or Facial Palsy ,Pakshaghat or Hemiplegia, Grudhrasi or Sciatica ,Pashangardabha or Mumps, Kadar or corn ,Indralupta or Alopecia areata ,Darunak or Dandruff, Niruddha Prakash or Phimosis ,Unmad or Hysteria ,Apasmar or Epilepsy ,
• Visit – www.ayurvedicfriend.com
Phone – 922 68 10 630
The Research topics and reseaech areas has been explained in ail, which are helpful for Undergraduates to get the research grants, PG Scholars and Ph.D Scholars to select theirs research topics..
Fracture & dislocation is well described in Ayurveda. Sushruta Samhita have a separate chapter for bhagna etiology, features, types, prognosis, Management by name of Bhagna-Kandabhagna-Sandhimukta. The basics principles and management of fracture are accurate as per modern orthopedics.
this is an ppt presentation by dr.b.arun kumar, who is working as a lecturer in MNR ayurvedic medical college, sangareddy, near hyderabad. in this presentation i given all details of virechana karma.
A practical understanding of Ksheera Vasthi. Some of the commonly practiced Ksheera Vasthi's are discussed here. KB is brumhana shodhana basti. KB can be prepared with varied Ksheerapaka for better effect in varied conditions based on yukti. It is widely used and effective in Asthivaha srotho vikara.
This topic is under the General Principles of Surgery for MBBS Students. It also deals with Scars & Contractures. The student should know to differentiate between Hypertrophic Scar & Keloid..
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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2. Definition
• वातादयो माांसमसृक् च दुष्ााः सन्दूषय मेदश्च कफानुविव्धमम् |
वृत्तोन्नतां विवग्रथितां तु शोफां कु ववन््यतो ग्रन्न्िरितित ्रदिदष्ाः || Su. Ni.
11/3
• Due to vitiation of doshas these doshas involve mansha and rakta
along with meda produces rounded, elevated shoph called granthi.
12. Pressure effects
• A cyst may press the neighboring structure specially the
blood vessels to cause venous congestion and varicosity of
vein.
• Cyst may press adjacent duct for e.g. choledochal cyst
compress common bile duct.
14. Treatment
• Symptomatic cyst should excise immediately to avoid
complication if cyst is small and asymptomatic then may
leave for later.
15. Sebaceous cyst
• These cyst develops due to blockage of mouth
of sebaceous gland, the gland become distended
with it’s own secretions. As the sebaceous gland
are present in skin so may be called as
epidermal cyst. Cyst lined by superficial
squamous cells.
• Common site
• Scalp
• Face
• Scrotum
• Back
There are no sebaceous gland in palm and sole ,
so no sebaceous gland will never present on palm
and sole.
16. Clinical feature
• These cysts are spherical in shape, always possess a small black spot
in center called punctum (except in scalp and scrotum).
• Usually Mobile, non-tender only became tender if got infection.
• These cyst always fix to the skin, skin above swelling can not be
lifted.
• Due to presence of sebum (pultaceous material) along with fat and
desquamated epithelial cell, inside the cyst, it’s consistency became
cystic and indentation will be present.
• Trans-illumination test will be negative.
17.
18. Treatment
• Total excision of cyst is treatment of choice.
• If cyst is inflamed due to infection give some conservative treatment
and excise when it become asymptomatic.
• An elliptical incision should be made including punctum and dissect
from surrounding tissue, take care while dissection to avoid rupture of
cyst. Removal of complete cyst wall is essential to avoid recurrence.
Before closing of wound with interrupted mattress suture heamostasis
must be achieved. Followed by ASD
• If the cyst is infected and full of pus then do I&D under local
anesthesia and treat like abscess. Leave the wound for healing with
secondary intension.
19.
20. Dermoid cyst
• This cyst lies in deep to the skin and lined by
skin, may called as epidermal cyst. These cyst
also contain pultaceous or tooth paste like
material which contain desquamated epithelial
cells. These cyst are lined by squamous
epithelial cells. Dermoid cyst never has
punctum.
• These are four types:
• Sequestration Dermoid
• Implantation Dermoid
• Tubulo Dermoid
• Teratomatous Dermoid
21. Sequestration Dermoid
• These cyst are congenital. These develops during embryonic development
when epithelium buried at the line of fusion. So these are found in the line
of fusion of two embryonic segments.
• These cyst are line by stratified epithelium with hair follicle, sebaceous
gland and sweat gland. Collection is pultaceous contains hairs, sebum and
desquamated cells.
Common site
• Midline of body neck, Outer canthus of eye
• Post auricular area
• Skull
• Midline of face (root of nose)
22. Clinical feature
• Cysts are usually congenital, painless, slowly growing and cosmetic
disfigurement is main complain. Hardly attain big size to give any
kind of serious effect and hardly infected.
• On palpation non-tender, mobile, free from skin (skin above swelling
can be lift), smooth regular surfaces cystic swelling.
• Indentation present.
• No punctum.
• These cysts are neither compressible nor reducible.
• Trans illumination is negative.
23. Treatment
• Surgical excision of complete cyst is the choice of treatment.
• If the cyst is present on skull, so before excision X-ray must be done
to confirm that cyst has not eroded skull bone.
• Excision method is same as sebaceous cyst.
Complication
• Infection
• Suppuration
• Ulceration
• Pressure on adjacent organ.
24.
25. Implantation Dermoid
• It is an acquired Dermoid arises from puncture injury on skin. Injury
leads the penetration of epithelium beneath the skin.
• Commonly found in gardeners, tailors and women.
• Common site are
• Palm of hand
• Fingers specially tip/pulp.
• Sole.
26. Clinical feature
• Patients usually have history of pricking injury
• On examination an tense cystic swelling, often firm/hard in consistency,
there may be scar of injury. Elicitation of fluctuation is difficult due to small
size and tension.
Treatment
• Complete excision is the choice of treatment
Complication
• Infection
• Suppuration
• Bursting
27. Teratomatous dermoid
• This is a cystic swelling develops from the totipotent cells with ectodermal predominance.
• Usually these cyst contain mesodermal elements like bone, cartilage etc. Hairs are almost
always present in cyst. So the usual content are bone, cartilage, tooth, hairs and cheesy
materials.
Example
• Ovarian cyst
• Testis-teratoma
• Mediastinal cyst
• Post anal Dermoid
• Retroperitoneal cyst
Treatment
• Complete Excision
Teratomatous dermoid
28. Tubulodermoid
• These cyst develops due to un-obliterated portion of congenital ectodermal
duct or tube.
• The cyst form due to accumulation of secretions of the line of ectodermal
cells of unobliterated portion of embryonic duct
Example
• Thyroglossal cyst
• Post-anal Dermoid
• Ependymal cyst in brain.
Treatment
• Complete Excision
Thyroglossal cyst