Recombinant DNA technology uses gene cloning to conduct genetic recombination, an exchange of genetic information between chromosomes. This process commonly involves reciprocal exchange of similar genetic material but can also involve inserting DNA segments into chromosomal sites with little matching DNA sequence, as seen in various biological systems.

2. Recombinant DNA Technology
Gene cloning
Genetic recombination is fundamental biological
process of exchange of genetic information between
different chromosomes.
Ordinary or generalized recombinational events
commonly involve the reciprocal exchange of genetic
material and require DNA sequence homology in the
regions of exchange Nonreciprocal recombinational
events. e.g. involving insertion of segments of DNA at
chromosomal sites that exhibit little or no sequence
homology, have also been documented in many biological
systems.