This document discusses different methods of teaching science and the research around their effectiveness. It describes how science instruction has changed over time from an early focus on memorization to a current emphasis on inquiry-based and hands-on learning. The two main methods discussed are content-based programs, characterized by textbooks and lectures, and inquiry-based programs, characterized by activities and experiments. Current research indicates that inquiry-based approaches that involve hands-on learning and direct experiences are most effective for nurturing intellectual development, though some barriers like teacher discomfort prevent widespread adoption.