This document summarizes research characterizing DNA methylation patterns in the Pacific oyster. The researchers found evidence that DNA methylation plays a regulatory role in oysters, particularly for stress response and immune genes. Understanding these epigenetic influences could help improve selective breeding programs by increasing predictability of traits. Future work involves further evaluating DNA methylation using new techniques like whole genome bisulfite sequencing to better understand environmental impacts and the role of epigenetics in hybrid vigor in oysters.