Gaudium IVF Clinic in Delhi - Genital Tuberculosis and Infertility : Tuberculosis is a disease that most of the people associate with the lungs, but surprisingly it can affect other organs of the body too, including the reproductive tract.
Tuberculosis (TB) is a very common disease worldwide including India. Tuberculosis of the female genital tract is
common enough to be found in 1% of women with DUB (Sutherland 1949) and in 4% of adolescent with excessive
menstrual loss (Sutherland 1953). The commonest site of involvement is the fallopian tubes (90e100%). The next
common site is endometrium (60%). The infection is from the tubes either by lymphatics or direct spread through
continuity. Symptoms vary according to the severity site and stage of the disease. Anti tuberculosis chemotherapy is the mainstay of tt. Initially drugs are used for 2 months. These are isoniazid, rifampicin, pyrazinamide and ethambutal. Treatment is continued for another 4 months with isoniazid and rifampicin.
female Genital tuberculosis,TB-PCR, female infertility, veerendrakumar cm
female genital TB poses stiffest challenge in the diagnosis, rapid molecular techniques have helped in arriving at a definitive diagnosis in suspicious clinical setting
Tuberculosis (TB) is a very common disease worldwide including India. Tuberculosis of the female genital tract is
common enough to be found in 1% of women with DUB (Sutherland 1949) and in 4% of adolescent with excessive
menstrual loss (Sutherland 1953). The commonest site of involvement is the fallopian tubes (90e100%). The next
common site is endometrium (60%). The infection is from the tubes either by lymphatics or direct spread through
continuity. Symptoms vary according to the severity site and stage of the disease. Anti tuberculosis chemotherapy is the mainstay of tt. Initially drugs are used for 2 months. These are isoniazid, rifampicin, pyrazinamide and ethambutal. Treatment is continued for another 4 months with isoniazid and rifampicin.
female Genital tuberculosis,TB-PCR, female infertility, veerendrakumar cm
female genital TB poses stiffest challenge in the diagnosis, rapid molecular techniques have helped in arriving at a definitive diagnosis in suspicious clinical setting
PID and its newer concepts.This presentation is done after grouping information from a variety of textbooks,journals and of course our professors.will definitely enlighten you
PID infection symptoms can be mild and subtle. Most women do not realize the infection until one experiences extreme symptoms such as severe pain in the lower abdomen and pelvis (bones that connect the trunk and legs) or pain during intercourse. Other symptoms include heavy vaginal discharge than usual with an unpleasant odor, abnormal levels of uterine bleeding, during intercourse or between menstrual cycles, fever with chills or even frequent or difficult painful urination. It is recommended that one visits the doctor as soon as any severe pain in the lower abdomen is seen with a fever, running into high temperatures or foul vaginal discharge and severe vomiting or nausea with the inability to contain anything that has been eaten
PID and its newer concepts.This presentation is done after grouping information from a variety of textbooks,journals and of course our professors.will definitely enlighten you
PID infection symptoms can be mild and subtle. Most women do not realize the infection until one experiences extreme symptoms such as severe pain in the lower abdomen and pelvis (bones that connect the trunk and legs) or pain during intercourse. Other symptoms include heavy vaginal discharge than usual with an unpleasant odor, abnormal levels of uterine bleeding, during intercourse or between menstrual cycles, fever with chills or even frequent or difficult painful urination. It is recommended that one visits the doctor as soon as any severe pain in the lower abdomen is seen with a fever, running into high temperatures or foul vaginal discharge and severe vomiting or nausea with the inability to contain anything that has been eaten
Pelvic inflammatory disease (PID) is a disease of the upper genital tract seen in women between 15 – 45 years of age and involves uterus (womb), fallopian tubes, ovaries and other areas within the pelvis. The infection affects the surface lining in all the above organs leading to damage with short and long term health implications.
Know More: http://www.fortisfertilitycentre.com/leading-fertility-doctors-bangalore
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An MBBS, MD, D.A.G.E (Germany), Dr. Khanna was born and brought up in Delhi in a family of freedom fighters and doctors. An alumni of Delhi Public School, RK Puram, and Medical College Baroda, she was a topper throughout her school and college education. She served as Senior Consultant at Sri Balaji Action Medical Institute from Year 2002 to Year 2011. Besides this Dr. Manika is a recipient of the Delhi Ratan Award (2008) and a Lifetime Member of the American Society of Reproductive Medicine. Apart from being an acclaimed IVF specialist, Dr. Khanna is a philanthropist at heart, actively involved in several support programs for the underprivileged.
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Gaudium IVF is now the most successful and advanced IVF institute of North India, (New Delhi, Punjab, Jammu Srinagar & Haryana). It was setup by renowned and awarded Dr. Manika Khanna (Delhi Ratan 2008, Recognized by The President of India, Mrs. Pratibha Patil, 2009) with the aim of delivering the joy of parenthood to childless couples. It has achieved more than 6000 IVF pregnancies in last 6 years. Gaudium has been recognized as the Best IVF Institute of India 2012 by the IVF India Magazine. And, Best IVF centre of the year 2014 by State Govt. It was also awarded the Best brand in IVF Surrogacy by the Brands Academy 2012. Gaudium is proud to have healthy babies in many cities across India and Overseas.
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VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
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GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
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2. Genital Tuberculosis and Infertility
Tuberculosis is a disease that most of the people associate with the lungs, but
surprisingly it can affect other organs of the body too, including the reproductive tract.
Caused by the tubercle bacillus, this is an infectious disease that can spread easily
through physical contact, making it all the more dangerous.
Genital TB, as the name suggests, has a direct influence on the genital tract and can
compromise the fertility of the patient. It is one of the major causes of female infertility
and is common in the reproductive age group (women who are between 15 to 40 years
of age).
The worst part of the condition is that it usually remains silent, without showing any
symptoms at all; most of the time, it is detected only when the patient comes across
infertility issues and the doctor tries to diagnose the exact cause of the same.
3. How does genital TB cause infertility?
Primarily, TB begins as a pulmonary disease, an infection of the lungs as the bacillus enters the
body on inhalation. Most people have the ability to ward off the infection and it remains silent
without causing any harm
Genital TB has a far-reaching impact on a woman’s fertility because it damages the vital
reproductive organs such as the fallopian tubes, ovaries and uterus. Commonly, the fallopian
tubes are targeted by the infection (salpingitis), while another reason of female infertility
caused by genital TB is that the endometrial lining of the uterus is damaged (endomteritis).
In the first condition, the fertilized egg is unable to make its way down the tubes into the
uterus; while the latter involves erosion of the endometrium, which results in failure of the
implantation of the embryo in the uterus.
4. Symptoms and Diagnosis of Genital TB
The challenge of this widespread condition is that its symptoms are not well-defined and
most of the times, it remains silent till it is too late. At the same time, a woman who has
previously suffered from pulmonary TB (and otherwise too) needs to be vigilant of
certain symptoms that can indicate the presence of the genital TB infection:
• Irregular menstrual cycle with periods being too scanty or excessively heavy
• Pain in the pelvic region
• Vaginal discharge stained with blood
• Pain and bleeding during/after intercourse
• Infertility
5. Endometrial Biopsy: The tissue sample of the endometrium is obtained using uterine curettage and
taken for biopsy to identify the existence of infection caused by the TB bacillus. A histological
diagnosis is seen as a reliable method to cinch the disease.
Culture Test: A culture test is performed to detect the presence of the bacillus, which is confirmed
by their growth in the lab. The test is again done on the sample of endometrial tissue obtained by
curettage.
Laparoscopy: A detailed laparoscopy may be recommended to find out the extent of damage to the
genital tract and also to establish whether it has been caused by genital TB.
Some other tests used to identify the condition include culture of menstrual blood,
ultrasonography, mycobacterium tuberculosis culture, cervical cytology, endoscopy and peritoneal
biopsy. When infection of fallopian tubes is suspected, diagnosis becomes difficult because it is
practically impossible to take tissue samples of the fallopian tube.
Diagnostic Tests Used for the Genital TB
6. Tubal obstruction and scarring of the ovaries and uterus are some complications caused by
genital TB. If the woman is not given timely treatment for the condition, she may
unfortunately lose her ability to conceive.
A six to eight month course of anti-TB medication is prescribed to curb the infection, while
restorative surgery is regarded as the more aggressive treatment option for genital TB The
woman will have to rely on assisted reproductive techniques such as ICSI or IVF Treatment
if the damage is beyond repair. For women who have lost hope completely as the genital
organs have been damaged extensively by the infection, the options of surrogacy and
adoption have to be considered
As it has always been said, prevention is better than cure in case of genital TB too. Women
should look to safeguard their fertility by protecting themselves from the pulmonary
infection to begin with.
Management and Treatment of Genital TB
7. Gaudium is a leading IVF Clinic in Delhi, India and is trusted for providing world class
facilities and advanced treatment for its patients. To get assistance for a variety of
reproductive and gynecological problems, along with the expert advice from the renowned
infertility specialist Dr. Manika Khanna, get in touch today.
Gaudium IVF Centre in Delhi
8. Address: A-41, Chander Nagar, Janakpuri West (Near Janakpuri West Metro
Station) New Delhi – 110 058 (India)
Phone: +91-11-69418485, +91-11-43528485, +91-11-84854359, +91-8527858585
+91-9899953963, +91-9810739199
Email: info@gaudiumivfcentre.com
Website: https://www.gaudiumivfcentre.com/
Founder and CEO: Dr. Manika Khanna (M.B.B.S., M.D., D.A.G.E. Germany)
Centre Incharge: Dr. Ambika Vaid (M.B.B.S., M.D. Gynaecology), Dr. Deepali
Kaushik (B.A.M.S Gynaecology)
Contact Us