This document discusses several projects at the Geary Institute aimed at understanding trends in health and well-being in Ireland over time. It finds that early life conditions are important for later health outcomes, and that conditions in the 1930s-1950s continue to impact the current aging population. Studying the health of Irish emigrants and using natural experiments can help disentangle the effects of early life factors from other influences. Analysis of a harsh winter in 1947 suggests early life shocks have long-term health consequences, particularly for lower socioeconomic groups. Understanding early life conditions is key for policymakers.
Anderson, Unorthodox Health Care Cost Reductionsjwanderso
Novel Big Hitter interventions that will have dramatic cost savings due to improved health. Chronic diseases of aging and how to prevent them with unorthodox, effective interventions.
This is a study using historical data and forecasts of life expectancy for several countries. The data and forecasts come from the UN - Population Division. While the historical data is most interesting, the forecasts are highly optimistic as they project a linear trend way into the future. Meanwhile, those forecasts should have followed a much more realistic logarithmic curve reflecting slower increase in life expectancy as the life expectancy rises.
Obesity is a leading preventable cause of death worldwide, with increasing prevalence in adults and children, and it as one of the most serious public health problems of the 21st century. Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity is most commonly caused by a combination of excessive food energy intake, lack of physical activity, and genetic susceptibility. Dieting and physical exercise are the mainstays of treatment for obesity. Diet quality can be improved by reducing the consumption of energy-dense foods such as those high in fat and sugars, and by increasing the intake of dietary fiber. Since obesity has grown to epidemic proportions, its effective management is a very important clinical issue. Despite the great amount of scientific effort that has been put into understanding the mechanisms that lead to overconsumption and overweight, at the moment very few approaches to weight management are effective in the long term. On the other hand, modern society is also affected by the growing incidence of eating disorders on the other side of the spectrum such as anorexia and bulimia nervosa which are equally difficult to treat. This review summarizes the current available scientific literature regarding the effect of NUTREASE POWDER, The Nature’s blend of protein, Fibers, plant extracts (phytochemicals) in human appetite and body weight.
Causes and consequences of mortality decline in less developed countries, Sa...Nishat Zareen
Causes and consequences of mortality decline in the less developed countries by Samuel H. Preston. This article is presented in the context of Bangladesh. The sole purpose of this paper is to identify the factors responsible for the dramatic decline of mortality rates in the less developed countries of Asia, Africa and Latin America. These factors were broadly termed as 'social and economic development' and 'technical changes'.
Can the health system sustain population explosion in indiaHarivansh Chopra
The present pandemic has taught us many lessons as far as health care delivery system is concerned in india. population growth is a neglected issue for many decades in india and it is well known that till we are able to control the growth ,all remedial action to improve health care go in vain.this presentation is highlighting the existing gaps in the provision of primary health care in india. we definitely need to increase the percentage of GDP on health as well as control the population.
Demography addresses human populations as population per se, that is, their sizes and structures.
It is the scientific study of human population.
Demographic processes :
1. fertility 4. migration &
2. mortality 5. social mobility
3. marriage
Instituto Academia de Formación Jurídica Simón Rodríguez
“Enseñanza Jurídica que transforma vidas”.
Somos una institución de Educación de Adultos, que germino legalmente el 17 de Julio del Año 2014, siendo registrada en el Ministerio del Poder Popular Para las Relaciones Interiores y Justicia, Servicio Autónomo de Registros y Notarias y ante los órganos educativos del Estado Venezolano, entre los que destacan el INCES y el Ministerio del Poder Popular para la Educación, dedicada a la formación continua de profesionales en el derecho, preparándolos para entender, comprender y desarrollar exitosamente su ejercicio jurídico.
Estamos ubicados en la Ciudad de Maracay Estado Aragua – Venezuela
www.iafjsr.com.ve
Anderson, Unorthodox Health Care Cost Reductionsjwanderso
Novel Big Hitter interventions that will have dramatic cost savings due to improved health. Chronic diseases of aging and how to prevent them with unorthodox, effective interventions.
This is a study using historical data and forecasts of life expectancy for several countries. The data and forecasts come from the UN - Population Division. While the historical data is most interesting, the forecasts are highly optimistic as they project a linear trend way into the future. Meanwhile, those forecasts should have followed a much more realistic logarithmic curve reflecting slower increase in life expectancy as the life expectancy rises.
Obesity is a leading preventable cause of death worldwide, with increasing prevalence in adults and children, and it as one of the most serious public health problems of the 21st century. Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity is most commonly caused by a combination of excessive food energy intake, lack of physical activity, and genetic susceptibility. Dieting and physical exercise are the mainstays of treatment for obesity. Diet quality can be improved by reducing the consumption of energy-dense foods such as those high in fat and sugars, and by increasing the intake of dietary fiber. Since obesity has grown to epidemic proportions, its effective management is a very important clinical issue. Despite the great amount of scientific effort that has been put into understanding the mechanisms that lead to overconsumption and overweight, at the moment very few approaches to weight management are effective in the long term. On the other hand, modern society is also affected by the growing incidence of eating disorders on the other side of the spectrum such as anorexia and bulimia nervosa which are equally difficult to treat. This review summarizes the current available scientific literature regarding the effect of NUTREASE POWDER, The Nature’s blend of protein, Fibers, plant extracts (phytochemicals) in human appetite and body weight.
Causes and consequences of mortality decline in less developed countries, Sa...Nishat Zareen
Causes and consequences of mortality decline in the less developed countries by Samuel H. Preston. This article is presented in the context of Bangladesh. The sole purpose of this paper is to identify the factors responsible for the dramatic decline of mortality rates in the less developed countries of Asia, Africa and Latin America. These factors were broadly termed as 'social and economic development' and 'technical changes'.
Can the health system sustain population explosion in indiaHarivansh Chopra
The present pandemic has taught us many lessons as far as health care delivery system is concerned in india. population growth is a neglected issue for many decades in india and it is well known that till we are able to control the growth ,all remedial action to improve health care go in vain.this presentation is highlighting the existing gaps in the provision of primary health care in india. we definitely need to increase the percentage of GDP on health as well as control the population.
Demography addresses human populations as population per se, that is, their sizes and structures.
It is the scientific study of human population.
Demographic processes :
1. fertility 4. migration &
2. mortality 5. social mobility
3. marriage
Instituto Academia de Formación Jurídica Simón Rodríguez
“Enseñanza Jurídica que transforma vidas”.
Somos una institución de Educación de Adultos, que germino legalmente el 17 de Julio del Año 2014, siendo registrada en el Ministerio del Poder Popular Para las Relaciones Interiores y Justicia, Servicio Autónomo de Registros y Notarias y ante los órganos educativos del Estado Venezolano, entre los que destacan el INCES y el Ministerio del Poder Popular para la Educación, dedicada a la formación continua de profesionales en el derecho, preparándolos para entender, comprender y desarrollar exitosamente su ejercicio jurídico.
Estamos ubicados en la Ciudad de Maracay Estado Aragua – Venezuela
www.iafjsr.com.ve
Como hacer una demanda_DOCTRINA ARGENTINAMauri Rojas
Instituto Academia de Formación Jurídica Simón Rodríguez
“Enseñanza Jurídica que transforma vidas”.
Somos una institución de Educación de Adultos, que germina legalmente el 17 de Julio del Año 2014, siendo registrada en el Ministerio del Poder Popular Para las Relaciones Interiores y Justicia, Servicio Autónomo de Registros y Notarias y ante los órganos educativos del Estado Venezolano, entre los que destacan el INCES y el Ministerio del Poder Popular para la Educación, dedicada a la formación de los futuros profesionales en el derecho en su fase incipiente, preparándolo para entender, comprender y desarrollar exitosamente su futura profesión y mejorar las habilidades y destrezas de profesionales que ya estén en su ejercicio profesional.
Estamos ubicados en la Ciudad de Maracay Estado Aragua – Venezuela
www.iafjsr.com.ve
Propagation of Policies in Rich Data FlowsEnrico Daga
Enrico Daga† Mathieu d’Aquin† Aldo Gangemi‡ Enrico Motta†
† Knowledge Media Institute, The Open University (UK)
‡ Université Paris13 (France) and ISTC-CNR (Italy)
The 8th International Conference on Knowledge Capture (K-CAP 2015)
October 10th, 2015 - Palisades, NY (USA)
http://www.k-cap2015.org/
Squire Technologies: Short Message Service Centre Presentation.
With the continuing growth and success of SMS traffic worldwide the SVI-SMSC Short Message Service Center can offer Operators with existing SS7 interconnects the ability to maximise their revenue by directly offering SMS services.
SAP sistemlerinin her geçen gün karmaşıklaşan dünyasında kullanıcıları yetkilerinin uçtan uca yönetilmesi ve hassas işlemlerin izlenmesi için merkezi bir uygulama zorunlu hale gelmeye başladı. SAP GRC Access Control ürünü ile kurumsal yetki denetim ve yönetimi metodolojimize göz atın.
Valoracion juridica del acta de inv penal2Mauri Rojas
Instituto Academia de Formación Jurídica Simón Rodríguez
“Enseñanza Jurídica que transforma vidas”.
Somos una institución de Educación de Adultos, que germina legalmente el 17 de Julio del Año 2014, siendo registrada en el Ministerio del Poder Popular Para las Relaciones Interiores y Justicia, Servicio Autónomo de Registros y Notarias y ante los órganos educativos del Estado Venezolano, entre los que destacan el INCES y el Ministerio del Poder Popular para la Educación, dedicada a la formación de los futuros profesionales en el derecho en su fase incipiente, preparándolo para entender, comprender y desarrollar exitosamente su futura profesión y mejorar las habilidades y destrezas de profesionales que ya estén en su ejercicio profesional.
Estamos ubicados en la Ciudad de Maracay Estado Aragua – Venezuela
www.iafjsr.com.ve
2013.04.17 The usefulness of a national wellbeing index for Public PolicyNUI Galway
Professor Liam Delaney, University of Stirling, UK presented this seminar "The usefulness of a national wellbeing index for Public Policy" as part of the Visiting Fellows Seminar Series at the Whitaker Institute on 17th April 2013.
Health Promotion Strategies and Methods Third Edition is the essential guide to developing effective health programs for the Australian population. The book presents the key principles of health promotion and demonstrates how they can be applied. This new edition provides a structured approach to devising health programs by focusing on planning, development and implementation. It also clearly explains the differences in individual, group and mass population approaches to health intervention and prevention programs. This is a practical introduction for health practitioners and students in public health, health sciences, medicine, nursing and epidemiology. Key features: • thoroughly revised and updated to reflect current health practices and incorporating the latest references • focuses on developing targeted strategies and techniques • written by Australian authors who are leaders in the field • useful tips, summaries and case studies throughout • concise and accessible style.
My Journey in Global Health: Part One of the TrilogyRenzo Guinto
Inaugural talk of the Alumni Lecture Series organized by my alma mater, University of the Philippines Rural High School (UPRHS) last Jamuary 9, 2015.
My talk is Part One ("Foundation") of my life's trilogy. Part Two ("Formation") and Part Three ("Fruition") will be delivered on my 50th and 75th birthdays, respectively.
Used for Medical Grand Rounds at several hospitals, this is data based comprehensive review of the shortcomings of the American Medical System and dysfunctional political attempts at reform. Single payer, Medicare for all, with elimination of for profit insurance companies is the best answer.
Social Determinants of Health: Why Should We Bother?Renzo Guinto
Presentation delivered during the 2nd Social Oncology Forum with the theme "Social Determinants of Health in Agricultural Communities." November 10, 2013, Benguet State University, La Trinidad, Benguet.
Hue Ump English Club Dec 09 Health OverviewBinhThang
This topic discused at Mortality,Morbidity in the Population and Sudden Infant Death Syndrome by Dr Professor Michael Dunne
QUT School of Public Health
Director, International Health Program.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
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