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1. N. Friedreich Ataxia
By Mohammad Zubair

2. What is ataxia?
Ataxia = A (lack of) taxia (coordination)

3. What is Friedreich's ataxia ?

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6. Genetics
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12. Signs and symptoms
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13. •Signs and symptoms cont….
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16. Diagnosis
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17. •Diagnosis cont…

18. Differential diagnosis

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20. 1. Idebenone
 short chain quinine analogue
 Act as potent antioxidant
and electron carrier
 Benefit neurological function
2. deferiprone (an iron chelator)
3. erythropoietin, pioglitazone
4. peroxisome proliferatoractivated receptors