For each problem in this homework, your assignment is to determine modes of inheritance for a set of phenotypes each of which is determined by genotypes at two independently assorting loci. The data come from an alien species of fly whose genetics is identical to that of earth flies. As part of your assignment, you must confirm your hypothesized modes of inheritance by applying a chi-square analysis. NOTE ABOUT DEGREES OF FREEDOM: In situations where the observed counts and the expected counts for a category are both 0, that category does not figure into the chi-square calculation, so that the degrees of freedom is reduced by one in such situations. The possible modes of inheritance are: (i) Autosomal recessive; (ii) Homozygous lethal (dominant); (iii) Sex-linked recessive. The Sex-linked recessive mode can only occur in females parents. Counts of phenotype pairs for the F1 generation give you clues as to the mode of inheritance of each phenotype. Good luck! ONE PHENOTYPE PER PARENT, TWO PHENOTYPES TOTAL For the Tratagorian Kumbus Fly, that lives on the planet Zeon, parental matings occur only among flies in which each parent has a disease phenotype at one locus and is wild-type at the other locus. Problem 4. A female with Flonasean eye color mates with a male with Muppetrus eye shape, producing the following counts: F1 Generation Males WT-WT Disease-WT WT-Disease Disease-Disease 0 242 0 247 Females WT- WT Disease-WT WT-Disease Disease-Disease 239 0 253 0 Solution It is sex linked recessive mode of inheritance due to which males are not affected and females are affected..

1. For each problem in this homework, your assignment is to determine modes of inheritance for a
set of phenotypes each of which is determined by genotypes at two independently assorting loci.
The data come from an alien species of fly whose genetics is identical to that of earth flies. As
part of your assignment, you must confirm your hypothesized modes of inheritance by applying
a chi-square analysis. NOTE ABOUT DEGREES OF FREEDOM: In situations where the
observed counts and the expected counts for a category are both 0, that category does not figure
into the chi-square calculation, so that the degrees of freedom is reduced by one in such
situations. The possible modes of inheritance are: (i) Autosomal recessive; (ii) Homozygous
lethal (dominant); (iii) Sex-linked recessive. The Sex-linked recessive mode can only occur in
females parents. Counts of phenotype pairs for the F1 generation give you clues as to the mode
of inheritance of each phenotype. Good luck! ONE PHENOTYPE PER PARENT, TWO
PHENOTYPES TOTAL For the Tratagorian Kumbus Fly, that lives on the planet Zeon, parental
matings occur only among flies in which each parent has a disease phenotype at one locus and is
wild-type at the other locus. Problem 4. A female with Flonasean eye color mates with a male
with Muppetrus eye shape, producing the following counts: F1 Generation Males WT-WT
Disease-WT WT-Disease Disease-Disease 0 242 0 247 Females WT-
WT Disease-WT WT-Disease Disease-Disease 239 0 253 0
Solution
It is sex linked recessive mode of inheritance due to which males are not affected and females
are affected.