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THERAPEUTIC ENDOSCOPY IN GI
         SURGERY


  PRESENTER : Dr . Sumit Sudhir Hadgaonkar
    MODERATOR : Prof. G.S.Moirangthem
WHAT IS ENDOSCOPY ???
•   Endoscopy Greek Word “Endo”means “Inside”
    “Skopeein ”means “To See”

•        Examination of the interior of a canal or hollow
    viscus by means of a special instrument, such as an
    endoscope.

•       Direct viewing interior of an organ is often very
    helpful in determining the cause of a problem &
    helpful in establishing a diagnosis.
History of Endoscopy
FIRST ENDOSCOPE by Philip Bozzini 1806




                 ‘Lichtleiter
• 1822 William Beaumont ,first introduced into human
  being.

• Maximilian Nitze ( 1848 – 1906) modified Edison`s
  light bulb and created the first electrical light bulb for
  using it for urological procedures

• Decelopement of first fiberoptic endoscope by Basil
  Hirschowitz in 1958.
• Electronic (charge coupled device) endoscpe
  developed in 1983.

• Thus the modern endoscope was born.

• Kurt Semm , a gynecologist , regarded as father of
  Modern Endoscopy.
Historical Landmarks in GI
                  Endoscopy
•   1968-Endoscopic Retrograde pancreatography
•   1969-Colonoscopic polypectomy
•   1970-Endoscopic Retrograde cholangiography
•   1974-Endoscopic Sphincterotomy
•   1979-Percutaneous Endoscopic Gastrostomy
•   1980-Endoscopic Injection Sclerothrapy
•   1980-Endoscopic ultrasound
•   1985-Endoscopic control of Upper GI bleeding
•   1990-Endoscopic Variceal Ligation
Parts of Endoscope
Complete Endoscope Assembly
Types of endoscopy




Diagnostic
             Therapeutic
Upper GI                 Small bowel



              Therapeutic



Bilio-pancreatic             Lower GI
Upper GI endoscopy:

Variceal bleed                Nonvariceal bleed

Therapeutic endoscopy in nonvariceal bleeding
• Stabilization first and then endoscopy.
• UGIE sensitive in 80-95% of cases
• Spontaneously stop in 70-85% (without
  coagulopathy) without further intervention
Endoscopic treatment options:
1.   Injection therapy
2.   Thermal therapy
3.   Endoscopic clipping
4.   Endoscopic band ligation


Endoscopic hemostasis should be
 followed by omeprazole infusion
 therapy for prevention of
 rebleeding from NBVV/ adherent
 clot
1) Injection therapy:
• Sclerosants:

1.   Epinephrine (alone or with saline)
2.   Absolute alcohol
3.   Thrombin in NS
4.   Sodium tetradecyl sulfate
5.   Polidocanal

• Efficacy – 90% with very low complications
Method:

•4mm 23G needle

•Submucosally at 3-4
sites

•1-2cm away from
bleeding vessel

•Inject 5-10ml at each
site
Thermal therapy:
1. Laser
2. Electric current



1) Laser       argon laser
               Nd-YAG laser
Laser:                        Electric current:
• Argon laser is not useful   • Monopolar: several
  in severe bleeding            thousand degree of
• Disadvantages:                heat
1. Risk of full thickness     • Disadv: Full thickness
   injury (tremendous           damage
   heat)                      • Bipolar:
2. Expensive                   heat- 100degree C
3. Lack of portability         Will induce coaptation
                               Overall success rate: 80-
                                95%
                               Rebleed rate: 10-20%
                               Perforation rate: 0.5%
Endoscopic clipping:
• One clip at one site- usually fall of in 7-10 days when
  bleeding site heals




Band ligation:
• Only possible in small sized nonfibrotic acute peptic
  ulcer bleeding.
Variceal bleeding
• 30% mortality even in hospitalisation.
• Rebleeding is significant in those 2/3rd who survive
  first bleeding attack.
• Stabilisation of patient first.
• Vasopressin infusion
• Sengstaken Blackmore tube (12-24 hours before
  sclerotherapy)
• Endoscopy:        Sclerotherapy

                EVBL(endosopic variceal band ligation)
Sclerotherapy:
• Mostly preferred- sodium tetradecyl sulfate
• For gastric varices start injection lust above GD
  junction and move proximally
• Intravariceal injection is better than perivariceal
• 20ml is total amount in one session
• 2nd session performed 5 days later
• Repeated at 1-3 weeks interval till all varices are
  ablated.
EVBL
• Therapy of choice for variceal bleeding
• Requires expertise
• Lower complication rates
Foreign body extraction:

• Ingested mostly by 2 groups- children (1-5 years)
                                adults (inebriated or
  psychiatric patients or prisoners)

• 80-90% will pass spontaneously

• 1% will require surgical intervention
Indications:
1.   Failure of objects to move for 48-72 hours
2.   Objects wider than 2cm or longer than 5cm
3.   Signs of respiratory compromise
4.   Inability to handle secretions
• Coins are most frequently the foreign body in
  children
• Removed with adequate sedation and patient in
  trendelenberg position
• Coin grasped with polypectomy snare or tenaculum
  forcep
• If coin is in stomach it will pass through.
• Meat impaction – MC foreign body
• Removed if >12hours
• Even though bolus passes through esophagoscopy is
  necessary to R/O any obstruction
• Sharp objects though small should be removed
• Ingested button batteries are harmful to esophagus
  and stomach (other parts passes readily)

• Only foreign body which should never be removed
  endoscopically- coccaine filled packs (risk of
  breakage)
Esophageal Stricture dilatation

• Patients presenting with dysphagia or odynophagia
• Barium swallow is done before endoscopy- structure
  and length and stricture
• Endoscopy- to identify lesion and biopsy
• Benign peptic ulcer stricture- MC
• 90% of peptic and radiation strictures- amenable to
  dilatation
• Goal- dilate up to 14-15mm (45F)
• Dilatation done in multiple sessions
Types of dilators:
1. Guide-wire type
2. Balloon type
3. Optical dilator

1) Guide-wire dilator:
• Rigid device made of PVC
• Metal olive (Eder-Puestow) and mercury filled
   dilators are obsolete now
• Has a hollow core and passed over endoscopic or
   fluoroscopic guide-wire
• Disadv: Direct visualization of dilatation
  process not possible
• Provides both axial and radial force
• Suitable for tight strictures
Balloon type
• Can be passed through endoscopic
  endoscope’s therapeutic channel
• Dilatation process directly visualized
• Has been tried for corrosive strictures (but
  rate of rupture increased)
Optical dilator:
• Similar to guide wire type
• But gastroscope can be passed through core
  enabling visualization of dilatation process.
• Malignant strictures due to unresectable
  tumors/ TEF require palliative dilatation and
  placement of stents.
Types of stents
Self expanding metalic
  stent(SEMS)
• Permanent
• Passed through working
  channel of colonoscope
  over delivery cathether
          OR
• Over fluroscopically
  placed guidewire
Silicone stent:
• Removable
• Used for benign
   strictures
Percutaneous endoscopic gastrostomy (PEG)
  and jejunostomy(PEG-J)
• Preferred method of enteral feeding for patients:
 unable to swallow
 chronic gastric compression
 supplemental nutrition
• These are less expensive, less invasive and safe than
  surgical gastrostomy
• Contraindication:
 Total esophageal obstruction
 Massive ascites
 Intraabdominal sepsis
• PEG-J placement is done by extension of PEG.
• By passing a jejunal tube through PEG.
• Indications: Gastroparesis
                  Severe gastroesophageal reflux
Treatment of achalasia cardia
1)Balloon dilatation:

short term success (<6 months in 75% of patients)

Repeated dilatation is required

2) Endoscopic injection of botulinum into LES:

Less inflammation & fibrosis than repeated dilatation

But results not durable

Initially effective in 60-85% of patients 50% recurrence
Induces severe fibrosis at GE junction difficult for
myotomy later
Endoluminal treatment of GERD:
• Recently introduced in USA.
• Still under process of approval by FDA
1) Endoclinch:
• Sutures placed intramucosaly only at GE junction
   (circumferentially)
• Overtube placement with 2 gastroscopes

 1st gastroscope         2nd gastroscope
 suction suture device   suture cutting –
                           knot tying
2) Plicator:
• Also a suture based technique to create a full
   thickness flap at GE junction.
• Serves as a barrier against reflux

3) Stretta:
• Blindly performed after localisation of LES
   endoscopically
• Delivery of radiofrequency ablation into LES and
   inducing collagen deposition to LES
• Thus adding more bulk and reducing compliance of
   LES.
Endoscopic Mucosal Resection(EMR)
• EMR is an endoscopic technique developed for
  removal of sessile or flat neoplasm confined to the
  superficial layers (mucosa and submucosa) of the GI
  tract.
• EMR cap method used to perform
• Effective treatment for Squamous cell carcinoma
  esophagus
• When used for Barrett’s esophagus 30% develop
  recurrence within 2 years.
• EMR is widely used for resection of flat benign
  colon lesions. Use for malignant polyps is questioned.
Endoscopic Submucosal
           Dissection(ESD)
• ESD has been developed for en bloc removal of large
  (usually more than 2 cm), flat GI tract lesions.
• Use less established for colonic lesions
• Use justified in stomach and esophageal cancers
  when restricted to mucosa. (around 3% lymph node
  positivity)
• 5 year survival rate for m1-m2 lesions around 95%.
Endoscopy for pancreatobiliary tree:
• Willium McKune introduced in 1968
• Endoscopic sphincterotomy described by German
  and Japanese surgeons.

 Endoscopic sphincterotomy:
• Sphincterotome consists of standard canula
  contaning wireloop 2-3cm of which is exposed near
  tip.
Indication:
Choledocholithiasis

Sphincter of oddi
dysfunction

Acute cholangitis

Acute gall stone
pancreatitis

Endoprosthesis
insertion
Endoscopic biliary stents
       Metallic stents                   Plastic stents
•   Self expanding                • Straight flaps at each end
•   Put in collapsed state (9F)     for easy insertion
•   After release (30F)           • Short lived ,require change
•   Long lived                      every 3-6 months
•   Less prone to sludge          • Removal easy
•   Danger of becoming
    irremovable
Indications of biliary stenting:

• Malignant strictures of CBD –favorable for lesion
  below bifurcation
• Benign strictures due to iatrogenic trauma or due to
  penetrating trauma
• Sclerosing cholangitis
• Choledochocoele
Pancreatic Stents
• Smaller in caliber than biliary stents
• Have side holes for drainage
Indications for pancreatic stenting

•   Bypass ductal leaks and strictures
•   Pancreatic divisum-for minor papilla stenting
•   Pancreatic fistula
•   Pancreatic pseudocyst – when cyst in connection
    with main pancreatic duct
Small Bowel Enterosopy
• Obscure GI bleeding is most common indication
• Best performed at laparotomy by telescoping small
  bowel
• Noninvasive techniques will make diagnosis in only
  50% cases
• Double balloon endoscopy (DBE) introduced
  in 2000 for examination of entire small bowel
  non invasively
• But DBE is labor intensive procedure and may take 1-
  3 hours
• capsule endoscopy , a substitute for small bowel
  Enteroscopy.
• But diagnostic yield is 50-60% for recent bleeding
  and far lower for remote bleeding.
Endoscopy for lower GI tract
1) Flexible sigmoidoscopy
2) Colonoscopy

1) Flexible sigmoidoscopy:
• Majority of indications are for malignancy only
• Very few therapeutic indications are:
 Detorsion of sigmoid volvulus
 Foreign body removal
 Distal stricture management
2) Colonoscopy:
Therapeutic uses:
• Hemostasis:
 Recent severe but currently inactive bleeding
 Stigmata of recent hemorrhage such as active
  bleeding, adherent clot, nonbleeding visible vessel
 Hemostasis achieved in same manner as UGIT
 Angiodysplasia and diverticulosis (MC cause of lower
  GI bleeding)
 Thermal techniques should be used with caution in
  proximal colon for hemostasis
• Polypectomy
 Most polyps >1cm are easily seen over colonoscope
 All colon visualization is necessary
 Polypectomy snare used for removing polyp
 Electrocautery used for Hemostasis
 Extremely large polyps- >1 session
 Ulcerated sessile indurated polyps may be malignant
  and best removed by surgery
• Colonic decompression
 Useful in
          Ogilvie's syndrome
          colonic volvulus
          sigmoid volvulus
 But decompression is not a definitive procedure-
  buys time for bowel preparation for elective surgery.
 Mucosa can be visualized for viability
 Recurrence common
Stricture dilatation
• Anastomotic stricture offer best result
• Balloon dilators most commonly used
• Endoscopic Nd- YAG laser used for malignant
  obstruction allowing recanalisation
• Stenting of malignant obstruction is appealing
  method.
RECENT ADVANCES
Natural Orifice Trans Endoscopic Surgery
 (NOTES) :
• PERFORMING SURGICAL PROCEDURES WITHOUT
  MAKING INCISIONS ON THE SURFACE OF THE
  BODY and LEAVING NO SCARS
• An experimental surgical technique- scar less
  abdominal operations performed with an multi-
  channel endoscope passed through a natural
  orifice (mouth, urethra, anus, vagina etc.)
PROCEDURES DESCRIBED
               TILL NOW
• Laboratory reports
  Cholecystectomy, Splenectomy,
  Tubal ligation, Gastrojejunostomy
  Pyloroplasty,
  Staging peritoneoscopy, Liver biopsy,
  Distal pancreatectomy,
  Ventral hernia repair,
  Gastric sleeve resection,
  Colectomy (right and left)
PROCEDURES DESCRIBED
             TILL NOW
Human cases
•   TG- appendectomy,
•   TV- cholecystectomy,
•   TG- cholecystectomy,
•   TG- gastro-enterostomy,
•   Cancer staging
• Internal incision is over stomach, vagina, bladder or
  colon, thus completely avoiding any external
  incisions or scars.
ADVANTAGES:

• No wound infection
• No incision hernia
• No post op adhesions
Can be ‘Future of Surgery’
 from -Minimal invasive surgery
   to -Least invasive surgery
Thanking you
Thanking you
       Thanking you

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THERAPEUTIC ENDOSCOPY IN GI SURGERY

  • 1. THERAPEUTIC ENDOSCOPY IN GI SURGERY PRESENTER : Dr . Sumit Sudhir Hadgaonkar MODERATOR : Prof. G.S.Moirangthem
  • 2. WHAT IS ENDOSCOPY ??? • Endoscopy Greek Word “Endo”means “Inside” “Skopeein ”means “To See” • Examination of the interior of a canal or hollow viscus by means of a special instrument, such as an endoscope. • Direct viewing interior of an organ is often very helpful in determining the cause of a problem & helpful in establishing a diagnosis.
  • 3. History of Endoscopy FIRST ENDOSCOPE by Philip Bozzini 1806 ‘Lichtleiter
  • 4. • 1822 William Beaumont ,first introduced into human being. • Maximilian Nitze ( 1848 – 1906) modified Edison`s light bulb and created the first electrical light bulb for using it for urological procedures • Decelopement of first fiberoptic endoscope by Basil Hirschowitz in 1958.
  • 5.
  • 6. • Electronic (charge coupled device) endoscpe developed in 1983. • Thus the modern endoscope was born. • Kurt Semm , a gynecologist , regarded as father of Modern Endoscopy.
  • 7. Historical Landmarks in GI Endoscopy • 1968-Endoscopic Retrograde pancreatography • 1969-Colonoscopic polypectomy • 1970-Endoscopic Retrograde cholangiography • 1974-Endoscopic Sphincterotomy • 1979-Percutaneous Endoscopic Gastrostomy • 1980-Endoscopic Injection Sclerothrapy • 1980-Endoscopic ultrasound • 1985-Endoscopic control of Upper GI bleeding • 1990-Endoscopic Variceal Ligation
  • 9.
  • 11.
  • 12.
  • 14. Upper GI Small bowel Therapeutic Bilio-pancreatic Lower GI
  • 15. Upper GI endoscopy: Variceal bleed Nonvariceal bleed Therapeutic endoscopy in nonvariceal bleeding • Stabilization first and then endoscopy. • UGIE sensitive in 80-95% of cases • Spontaneously stop in 70-85% (without coagulopathy) without further intervention
  • 16.
  • 17.
  • 18. Endoscopic treatment options: 1. Injection therapy 2. Thermal therapy 3. Endoscopic clipping 4. Endoscopic band ligation Endoscopic hemostasis should be followed by omeprazole infusion therapy for prevention of rebleeding from NBVV/ adherent clot
  • 19.
  • 20. 1) Injection therapy: • Sclerosants: 1. Epinephrine (alone or with saline) 2. Absolute alcohol 3. Thrombin in NS 4. Sodium tetradecyl sulfate 5. Polidocanal • Efficacy – 90% with very low complications
  • 21. Method: •4mm 23G needle •Submucosally at 3-4 sites •1-2cm away from bleeding vessel •Inject 5-10ml at each site
  • 22. Thermal therapy: 1. Laser 2. Electric current 1) Laser argon laser Nd-YAG laser
  • 23. Laser: Electric current: • Argon laser is not useful • Monopolar: several in severe bleeding thousand degree of • Disadvantages: heat 1. Risk of full thickness • Disadv: Full thickness injury (tremendous damage heat) • Bipolar: 2. Expensive  heat- 100degree C 3. Lack of portability  Will induce coaptation  Overall success rate: 80- 95%  Rebleed rate: 10-20%  Perforation rate: 0.5%
  • 24. Endoscopic clipping: • One clip at one site- usually fall of in 7-10 days when bleeding site heals Band ligation: • Only possible in small sized nonfibrotic acute peptic ulcer bleeding.
  • 25. Variceal bleeding • 30% mortality even in hospitalisation. • Rebleeding is significant in those 2/3rd who survive first bleeding attack. • Stabilisation of patient first. • Vasopressin infusion • Sengstaken Blackmore tube (12-24 hours before sclerotherapy) • Endoscopy: Sclerotherapy EVBL(endosopic variceal band ligation)
  • 26. Sclerotherapy: • Mostly preferred- sodium tetradecyl sulfate • For gastric varices start injection lust above GD junction and move proximally • Intravariceal injection is better than perivariceal • 20ml is total amount in one session • 2nd session performed 5 days later • Repeated at 1-3 weeks interval till all varices are ablated.
  • 27.
  • 28. EVBL • Therapy of choice for variceal bleeding • Requires expertise • Lower complication rates
  • 29. Foreign body extraction: • Ingested mostly by 2 groups- children (1-5 years) adults (inebriated or psychiatric patients or prisoners) • 80-90% will pass spontaneously • 1% will require surgical intervention
  • 30. Indications: 1. Failure of objects to move for 48-72 hours 2. Objects wider than 2cm or longer than 5cm 3. Signs of respiratory compromise 4. Inability to handle secretions
  • 31. • Coins are most frequently the foreign body in children • Removed with adequate sedation and patient in trendelenberg position • Coin grasped with polypectomy snare or tenaculum forcep • If coin is in stomach it will pass through.
  • 32. • Meat impaction – MC foreign body • Removed if >12hours • Even though bolus passes through esophagoscopy is necessary to R/O any obstruction • Sharp objects though small should be removed
  • 33. • Ingested button batteries are harmful to esophagus and stomach (other parts passes readily) • Only foreign body which should never be removed endoscopically- coccaine filled packs (risk of breakage)
  • 34. Esophageal Stricture dilatation • Patients presenting with dysphagia or odynophagia • Barium swallow is done before endoscopy- structure and length and stricture • Endoscopy- to identify lesion and biopsy • Benign peptic ulcer stricture- MC • 90% of peptic and radiation strictures- amenable to dilatation • Goal- dilate up to 14-15mm (45F) • Dilatation done in multiple sessions
  • 35. Types of dilators: 1. Guide-wire type 2. Balloon type 3. Optical dilator 1) Guide-wire dilator: • Rigid device made of PVC • Metal olive (Eder-Puestow) and mercury filled dilators are obsolete now • Has a hollow core and passed over endoscopic or fluoroscopic guide-wire
  • 36. • Disadv: Direct visualization of dilatation process not possible • Provides both axial and radial force • Suitable for tight strictures
  • 37. Balloon type • Can be passed through endoscopic endoscope’s therapeutic channel • Dilatation process directly visualized • Has been tried for corrosive strictures (but rate of rupture increased)
  • 38. Optical dilator: • Similar to guide wire type • But gastroscope can be passed through core enabling visualization of dilatation process. • Malignant strictures due to unresectable tumors/ TEF require palliative dilatation and placement of stents.
  • 39.
  • 40. Types of stents Self expanding metalic stent(SEMS) • Permanent • Passed through working channel of colonoscope over delivery cathether OR • Over fluroscopically placed guidewire
  • 41. Silicone stent: • Removable • Used for benign strictures
  • 42. Percutaneous endoscopic gastrostomy (PEG) and jejunostomy(PEG-J) • Preferred method of enteral feeding for patients:  unable to swallow  chronic gastric compression  supplemental nutrition • These are less expensive, less invasive and safe than surgical gastrostomy • Contraindication:  Total esophageal obstruction  Massive ascites  Intraabdominal sepsis
  • 43. • PEG-J placement is done by extension of PEG. • By passing a jejunal tube through PEG. • Indications: Gastroparesis Severe gastroesophageal reflux
  • 44.
  • 45. Treatment of achalasia cardia 1)Balloon dilatation: short term success (<6 months in 75% of patients) Repeated dilatation is required 2) Endoscopic injection of botulinum into LES: Less inflammation & fibrosis than repeated dilatation But results not durable Initially effective in 60-85% of patients 50% recurrence
  • 46. Induces severe fibrosis at GE junction difficult for myotomy later
  • 47. Endoluminal treatment of GERD: • Recently introduced in USA. • Still under process of approval by FDA 1) Endoclinch: • Sutures placed intramucosaly only at GE junction (circumferentially) • Overtube placement with 2 gastroscopes 1st gastroscope 2nd gastroscope suction suture device suture cutting – knot tying
  • 48. 2) Plicator: • Also a suture based technique to create a full thickness flap at GE junction. • Serves as a barrier against reflux 3) Stretta: • Blindly performed after localisation of LES endoscopically • Delivery of radiofrequency ablation into LES and inducing collagen deposition to LES • Thus adding more bulk and reducing compliance of LES.
  • 49. Endoscopic Mucosal Resection(EMR) • EMR is an endoscopic technique developed for removal of sessile or flat neoplasm confined to the superficial layers (mucosa and submucosa) of the GI tract. • EMR cap method used to perform • Effective treatment for Squamous cell carcinoma esophagus • When used for Barrett’s esophagus 30% develop recurrence within 2 years. • EMR is widely used for resection of flat benign colon lesions. Use for malignant polyps is questioned.
  • 50.
  • 51. Endoscopic Submucosal Dissection(ESD) • ESD has been developed for en bloc removal of large (usually more than 2 cm), flat GI tract lesions. • Use less established for colonic lesions • Use justified in stomach and esophageal cancers when restricted to mucosa. (around 3% lymph node positivity) • 5 year survival rate for m1-m2 lesions around 95%.
  • 52. Endoscopy for pancreatobiliary tree: • Willium McKune introduced in 1968 • Endoscopic sphincterotomy described by German and Japanese surgeons. Endoscopic sphincterotomy: • Sphincterotome consists of standard canula contaning wireloop 2-3cm of which is exposed near tip. Indication:
  • 53. Choledocholithiasis Sphincter of oddi dysfunction Acute cholangitis Acute gall stone pancreatitis Endoprosthesis insertion
  • 54. Endoscopic biliary stents Metallic stents Plastic stents • Self expanding • Straight flaps at each end • Put in collapsed state (9F) for easy insertion • After release (30F) • Short lived ,require change • Long lived every 3-6 months • Less prone to sludge • Removal easy • Danger of becoming irremovable
  • 55.
  • 56.
  • 57. Indications of biliary stenting: • Malignant strictures of CBD –favorable for lesion below bifurcation • Benign strictures due to iatrogenic trauma or due to penetrating trauma • Sclerosing cholangitis • Choledochocoele
  • 58. Pancreatic Stents • Smaller in caliber than biliary stents • Have side holes for drainage
  • 59. Indications for pancreatic stenting • Bypass ductal leaks and strictures • Pancreatic divisum-for minor papilla stenting • Pancreatic fistula • Pancreatic pseudocyst – when cyst in connection with main pancreatic duct
  • 60. Small Bowel Enterosopy • Obscure GI bleeding is most common indication • Best performed at laparotomy by telescoping small bowel • Noninvasive techniques will make diagnosis in only 50% cases
  • 61. • Double balloon endoscopy (DBE) introduced in 2000 for examination of entire small bowel non invasively
  • 62. • But DBE is labor intensive procedure and may take 1- 3 hours • capsule endoscopy , a substitute for small bowel Enteroscopy. • But diagnostic yield is 50-60% for recent bleeding and far lower for remote bleeding.
  • 63. Endoscopy for lower GI tract 1) Flexible sigmoidoscopy 2) Colonoscopy 1) Flexible sigmoidoscopy: • Majority of indications are for malignancy only • Very few therapeutic indications are:  Detorsion of sigmoid volvulus  Foreign body removal  Distal stricture management
  • 64. 2) Colonoscopy: Therapeutic uses: • Hemostasis:  Recent severe but currently inactive bleeding  Stigmata of recent hemorrhage such as active bleeding, adherent clot, nonbleeding visible vessel  Hemostasis achieved in same manner as UGIT  Angiodysplasia and diverticulosis (MC cause of lower GI bleeding)  Thermal techniques should be used with caution in proximal colon for hemostasis
  • 65. • Polypectomy  Most polyps >1cm are easily seen over colonoscope  All colon visualization is necessary  Polypectomy snare used for removing polyp  Electrocautery used for Hemostasis  Extremely large polyps- >1 session  Ulcerated sessile indurated polyps may be malignant and best removed by surgery
  • 66. • Colonic decompression  Useful in Ogilvie's syndrome colonic volvulus sigmoid volvulus  But decompression is not a definitive procedure- buys time for bowel preparation for elective surgery.  Mucosa can be visualized for viability  Recurrence common
  • 67. Stricture dilatation • Anastomotic stricture offer best result • Balloon dilators most commonly used • Endoscopic Nd- YAG laser used for malignant obstruction allowing recanalisation • Stenting of malignant obstruction is appealing method.
  • 68. RECENT ADVANCES Natural Orifice Trans Endoscopic Surgery (NOTES) : • PERFORMING SURGICAL PROCEDURES WITHOUT MAKING INCISIONS ON THE SURFACE OF THE BODY and LEAVING NO SCARS • An experimental surgical technique- scar less abdominal operations performed with an multi- channel endoscope passed through a natural orifice (mouth, urethra, anus, vagina etc.)
  • 69. PROCEDURES DESCRIBED TILL NOW • Laboratory reports Cholecystectomy, Splenectomy, Tubal ligation, Gastrojejunostomy Pyloroplasty, Staging peritoneoscopy, Liver biopsy, Distal pancreatectomy, Ventral hernia repair, Gastric sleeve resection, Colectomy (right and left)
  • 70. PROCEDURES DESCRIBED TILL NOW Human cases • TG- appendectomy, • TV- cholecystectomy, • TG- cholecystectomy, • TG- gastro-enterostomy, • Cancer staging
  • 71. • Internal incision is over stomach, vagina, bladder or colon, thus completely avoiding any external incisions or scars.
  • 72.
  • 73. ADVANTAGES: • No wound infection • No incision hernia • No post op adhesions
  • 74. Can be ‘Future of Surgery’ from -Minimal invasive surgery to -Least invasive surgery