Basic file operations in C++ involve opening, reading from, and writing to files. The key classes for input/output with files are ofstream for writing, ifstream for reading, and fstream for both reading and writing. A file must first be opened before performing any operations on it. Common operations include writing data to files with put() or write(), reading data from files with get() or read(), and closing files after completion. Proper opening modes and error handling should be used to ensure successful file input/output.