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F.	Benoudiba,	JL	Sarrazin,	A	Ladoux,	JB	Billaud,	D	Ducreux	
Neuroradiology	Department	
CHU	Kremlin	Bicêtre	
	
hearing: Sense organ 	
Hanoi,	nov	2015
• 3 distinct parts
• The acoustic meatus
•  Pinna
•  External acoustic meatus
•  Acoustic wave propagation
•  Protection of the middle ear and resonance
Anatomy and physiology
of hearing
•  Eardrum
•  Middle ear
•  Contents:
•  Auditory ossicles Amplify the
vibration of the eardrum
• Malleus, uncus and stapes
•  Eustachian tube: connecting the
middle ear to the rhinopharynx:
equalizing air pressure on both
sides of the eardrum
• Adaptation of impedance
• Transformation vibration wave
to mechanical energy
Middle ear
• Mastoid
• Communication with
the mastoid air cells
and the epitympanic
recess
• windows
• Round window
• Oval window
Middle ear
• Content:
• Facial Nerve
Middle ear
•  Vestibule and semi circular
canals: Balance
•  Cochlea
•  Hearing part of the inner ear
• 35mm long
• Spiral around a bony
structure
• 2 spires 1/2
• 2 scala separated by the
spiral lamina
• Filled with peri lymph
Stapes	
Fenestra	vestibuli	
Apex	of	cochlea	
Scala	vestibuli	
Scala	Tympani	
Organe	of	
Corti	
Inner ear
• Scala Media
• Triangular-shaped duct
•  contain the organ of
hearing: Organ of Cort
• Filled with endolymph
Organe of
Corti
Scala	vestibuli	
Scala	tympani	
Inner ear
• Organe of Corti
Tectorial	membran	
Outer	hair	cells(10500)	
3	rows	(W)	
Inner	hair	cells	
(3500	fibers)	
1	row	
Cochlear	nerve	
10/CCI	
Basilar	membran	
Inner ear Reissner’s	membran
Central auditory system : Cochlear Nucleï
Posterior Nucleus
Anterior nucleus
Unilateral	afferents	
	
Sound	intensity,	fréquency	and	duration
Cochlear Nucleus: superior olivary complex
Bilatéral Information
•  Spatial location
•  Binaural interaction
•  Motor response to a sound
Lateral lemniscus
Spatial location
Inferior Colliculus
Ø  Crossroad between acsending and descending
fibers
Ø  Complex auditory information
Ø  located just below the visual processing centers
Auditory Thalamus
Medial geniculate nucleus
Posterior group of thalamus
Reticular nucleus
§  Auditory lateralization
Primary
auditory cortex:
area 41
a
b	
c	
d	
e	
41
42
Hemispheric inter connexion
1. Anterior commissure of the cerebrum
connecting the temporal lobe
2. Auditory tract over corpus callosum
	
MRI auditory system
SOUND:
Air pressure vibration
Vibration of the eardrum
MAE	
Sound =Mechanical
Energy
focus
Ossicles amplification
Endolymph fluid agitation
Hydraulic pressure
OHC: amplification
IHC: frequency
Cochlear nerve =
Electrical energy
Electrochemical signals to
brain
Physiology of Audition
• Cochlea tonotopy:
•  Cochlea is capable of exceptional sound analysis, in
terms of both frequency and intensity.
•  Higher frequencies cause movement in the base
of the cochlea, and deeper frequencies work at
the apex.
• Cochlear nuclei tonotopy
•  Apex fibers: surface of nucleus
•  Base fibers: depth of nucleus
Physiology of Audition
Physiology of Audition
Auditory messages are
conveyed permanently to
the brain via two types of
pathway:
the primary auditory
pathway which exclusively
carries messages from the
cochlea
the non-primary pathway
(also called the reticular
sensory pathway) which
carries all types of sensory
messages.
a
b	
c	
d	
e	
Neurophysiology of audition
•  Primary auditory cortex: tonotopic
representation. Topographic map of
cochlea
•  Stimulation:auditory hallucinations
contralateral ear
•  Secondary auditory cortex: spatial
localisation of sound, memory audition
•  Stimulation: auditory illusions
•  Broca’s area: articulation of speech
•  Wernicke’s area: speech perception
Neurophysiology of audition
•  Some examples in music:
•  Left hemisphere : rythm
•  Right hemisphere : Melody et
Harmony
•  Primary auditory cortex: height and
sound volume
•  Secondary auditory cortex: Harmony,
Melody and Rythm
•  Motor cortex: vocals and playing an
instrument
•  Hippocampus: memory
•  Cerebellum: rythm pathways (beat the
measure, tapping the feet to the beat)
Corpus callosum
Temporal	variation	of	brain	activity	induced	by	a	classical	music	stimuli	
Connectopedia	with	RTConTrack	Technology
•  Medical history
•  Uni or bilateral deafness
•  Acquired, evolutive
•  Otoscopy
•  Tympanometry
•  Acoustic reflex (if recruitment: endo cochlear lesion)
•  Audiometric tests:
•  Rinne CA>CO Nl ou SP
CO>CA ST
•  Weber: Nl: vibration both ear
ST: sick side
SP: healthy side
Clinical diagnosis
• Audiogram:
•  Tonal : graph
•  Vocal : patient’s ability to understand
words
AEP: Electric activity cochlea
Clinical diagnosis
ST	
SP	
S	Mixte	
Unconformity tonal and
vocal: retro cochlear lesion
	
	
brainstem
HEARING LOSS
• A number of pathological, genetic and epigenetic factors
can cause hearing loss	
• May involve any part of the sensory structure
	
• 3 types Conductive earing loss
EAM
ME
Sensorineural : Inner ear, IAM, central	
Mixed : SP + Conductive
Imaging
Deafness
Conductive Sensorineural
CT IV -
Cone beam
MRI
IAM
Inner ear
Brain
+/- CT
Malformations Trauma
otosclerosis
Conductive earing loss: causes
Mechanical obstruction
Infectious
Tumor
Trauma
Earwax, external
epidermal
Cholesteatoma
Malformation
Coforign body
Exostosis et osteoma
EMO
External otitis
Benign
Malignant
•  EAM
Conductive earing loss: causes
Malformation
Inflammatory
•  Middle ear
Ossicles
windows
Chronic
Suppurative otitis
tympanosclerosis
Cholesteatoma
Conductive earing loss:
causes
Otosposclerosis
Traumatic
•  Middle ear
Tumor
Meningioma
Adenoma
Paraganglioma
Hémangioma VII
Schwanomma VII
Sensorineural earing
loss: causes
Inner ear
Malformation
•  Cochlea
•  Aquecduct dilatation
Otosclerosis
Paget
Osteogenesis
imperfecta
Labyrinthic schwanomma
Labyrinthic hemorrage
Traumatic
Presbyacousia
Toxics Endolymphatic papilloma
Sensorineural earing
loss: causes
MAI
Malformation
Agenesia, hypoplasia CN
Infectious
Schwanomma	
Meningioma
Lymphoma
Metastasis
Inflammatory
Sensorineural earing loss: causes
PCA
Schwanomma VIII, VII, IX,X,XI,XII
Cystic lesions EC, AC
Meningioma
Lipoma
Aneurysm
Cartilaginous tumor
(chondroma,
chondrosarcoma)
Sensorineural earing loss: causes
Central
Traumatic
Inflammation
ischemic
Infectious
Siderosis
Dementia
Parkinson
Central deafness
• Surdité Verbale:
•  Impossibilité de reconnaître les mots entendus.
•  Possibilité	de	parole	spontanée	
•  Atteinte bilatérale cortex temporal.
• Agnosie auditive:
•  Impossibilité de reconnaître les sons et bruits
environnants.
•  Infarctus capsules externes ou corps genouillés
• Amusie
•  Impossibilité de reconnaître la musique
•  The auditory system has a complex organization
•  It revolves around a dual relationship :
•  Anatomical structure with perceptual function
•  Complex structure combining perception and cognition.
•  The deafness causes are many and varied and a good knowledge of anatomy ,
physiological , clinical and para-clinical and etiological diagnostic will
approach adapted diagnosis to a single symptom but with multiple etiologies.

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