The document classifies exoskeletons and orthoses into devices that act in series or parallel to human limbs, and provides examples of each. It discusses major design challenges and future directions for improving exoskeleton and orthosis technologies to enhance human strength, endurance and mobility. Specifically, it outlines four categories of exoskeletons/orthoses, reviews their hardware, actuation and control systems, and identifies challenges such as improving energy efficiency that still need addressing going forward.