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AN APPROACH TO
EVALUATION OF PELVIC
  MASSES IN WOMEN
          1
Learning objectives

!   to formulate a list of
  differentials for a patient with
  a pelvic mass

!   identify the risk factors for
  malignancy

!   to establish a system of
  evaluation for such tumours


                                    2
These are growths that are
associated with the reproductive

                                    What are they?
              tract

They include tumours arising from
 the female reproductive organs

    Although pertinent, breast
  tumours will not be discussed
               here




                                      3
Why the fuss?


!   We all worry about
  cancer

!   As such, all growths
  should be suspected
  cancerous

!   It is our duty to confirm
  non-malignancy
                                4
We all worry about cancer




            5
The objectives when a growth is
          discovered
                       !   Most importantly,
                            assess the
                           probability of
                            malignancy

                       !   If malignancy is
                          less likely, then
                            assess the
                          association with
                               fertility

                            !   Plan for
                        management, most
                          likely surgery



               6
Aetiology




    7
Concepts on aetiology

!   most premenopausal tumours are benign in origin

!   malignancy can occur at all ages

     !   this risk increases with age

!   postmenopausal women require aggressive evaluation

   !   cancer until proven otherwise



                             8
General Causes
!   Uterine fibroids              !   Ovarian cysts

! Adenomyosis (older pt)            •  Epithelial (arising from ovarian
                                       epithelium)
!   Functional cysts -
                                         - Serous & mucinous
  occasionally grow large &
  symptomatic                            - most common

!   Pregnancy                       •  Germ cell (from egg-producing
                                       cells)

                                         - In younger women

                                    •  Stromal ( from hormone
                                       producing cells)

                              9
In the reproductive age group
!   functional cysts (follicular or luteal) are most common

   !   usually small but may become larger - 10 cm


!   frequently asymptomatic but can have dull, non-
  specific pain
   !   mostly due to intracystic haemorrhage


! tumours are rare - most common dermoid cysts &
  benign teratomas

!   never forget pregnancy!

                                     10
nongynae causes
                Don t forget there s other stuff in the pelvis!




Brown G. A gynecologic approach to evaluation of pelvic masses in women JAAPA 2012
                                      11
Symptoms




   12
The asymptomatic patient


!   during a routine medical
  check up – physical
  exam, U/S scan etc

!   from Pap smear results




                               13
Abnormal Vaginal Bleeding
!   usually occurs with tumours of lower tract

    !   endometrial, myometrial cervical etc..

!   fibroids are prone to heavy cyclical bleeding

!   irregular, non-menstrual bleeding is more sinister

! postcoital bleed suggests intravaginal location

    !   polyps and cancers can occur, but infection is the most
       common cause

!   ovarian tumours mostly bleed if cancerous, & only when advanced

                                    14
Abdominal pain
!   ascertain if cyclical/dysmenorrhoea - more likely
  endometriosis or PID

!   how long has it been there?

!   If it has been there for a long time, is it progressively
  worsening?

!   remember abdominal quadrants,

    !   usually, the pain will be overlying the offending
      organ
                               15
Nonspecific symptoms

!   bowel or urinary, these usually are sinister
  associations with the tumour

!   endometriosis and/or adhesions may mimic these

!   other symptoms that should be questioned include
  appetite & weight loss



                              16
Infertility

!   women in the reproductive age group must be
 questioned on this

!   endometriosis & adenomyosis are among the most
 common causes of the pelvic mass

 !   the association of this symptom with a mass in most
   cases is due these conditions



                           17
Ovarian cancer

!   often manifests late

!   abdominal or pelvic pain

!   bloating

!   abdominal distension

!   other nonspecific symptoms



                               18
Postmenopausal patient
!   any tumour here warrants
  extensive investigation

!   postmenopausal bleeding
  must be taken seriously

!   commonest tumours at this
  age are ovarian

    !   may present only with
      nonspecific symptoms

    !   the pelvis should be
      looked at carefully

                                19
SUMMARY OF !
  TUMOUR!
                             CLINICAL FEATURES!



                           heavy cyclical menstruation,
   fibroids !           irregularly enlarged, mobile smooth
                            uterus, usually non-tender


                     nonspecific pelvic or abd pain,
                    bloating, constitutional symptoms,
ovarian cancer!
                    fixed mass, may be irregular, firm,
                   hard or soft, ascites may be present

                   cyclical pain, dyspareunia, infertility,
                    abnormal menstruation,soft-to-firm
endometrioma!
                      mass, usually fixed, lateral or
                                   central

                  20
Signs




  21
Inspection
!   overall, the patient
  may look unwell

!   she may be in
  extreme pain

!   the abdomen may be
  distended, generally
  or asymmetrically

!   the umbilicus may be
  deviated

!   if acute, the abdomen
  may not move with
  respiration

                               22
Palpation
!   is the surface smooth or nodular?

!   nodularity is not good

!   is the mass fixed or mobile

!   consistency - hard, firm or soft




                                  23
Can you go below the
      mass?




!   important to feel if you can go
   below the mass

if not, then it is most likely arising
    from the pelvis

                  	

          24
Ascites

     !   this is never
       a good sign

     !   you must
       know how to
       evaluate for
       shifting
       dullness


25
Cervicovaginal inspection
!   do not forget to
  assess below!




                       26
An overview of cancers


https://www.dropbox.com/s/whhmrateafmqus7/gynaecancers.pdf	





                           27
some common conditions




          28
Ovarian Cysts




      29
!   quite
  common at
  a later age,
  about 40s

!   may be
  asymptomat
  ic, but most
  often cause
  heavy
  menstruatio
  n




                 30
                      Fibroids
Endometriosis


!   May present as
  either
  adenomyosis
  (uterine
  enlargement),

!   a cyst or


!   both.
                     31
Adenomyosis
              Can be a diffuse or globular
                       swelling
K	

            Endometrium-like tissue is found
             embedded within myometrium




       32
Funny
                      things
                     are seen

This is a fibroid!


        33
The most
     common
     growth -
       fat!




34
Investigations




      35
Role of ultrasound

!   an essential tool for diagnosis - first Ix to be
  considered

!   any mass must initially be scanned

!   abdominal or transvaginal

!   features to look for include composition of tumour,
  size, uni- or bilateral and presence of ascites


                               36
Ultrasound
     TVS image produces greater
             resolution


37
Blood tests


!   General - assess cell lines for health & mx issues

!   Tumour markers - limited diagnostic capability

   •  May be used as surveillance when increased

!   Other tests depend on type of tumour




                              38
Other imaging


!   MRI & CT

!   Laparoscopy - can be diagnostic, but better to be
  therapeutic




                            39
summary




   40
Key points
!   pelvic masses may have a benign or malignant
  aetiology

    !   the risk of malignancy is increased in
      postmenopausal women

!   premenopausal masses are usually benign

!   evaluation of premenopausal masses must include
  relationship with fertility

!   U/S is an important evaluation tool for possibility of
  malignancy
                                41
References

!   Brown G. A gynecologic approach to evaluation of pelvic masses in women JAAPA
  2012

!   Johnson BA. Evaluation of pelvic masses 2001
  http://www.eric.vcu.edu/home/resources/whh/
  VIIIeEVALUATION_PELVIC_MASSES.pdf




                                         42
Let s have coffee!




     43

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Evaluate pelvic tumours

  • 1. AN APPROACH TO EVALUATION OF PELVIC MASSES IN WOMEN 1
  • 2. Learning objectives !   to formulate a list of differentials for a patient with a pelvic mass !   identify the risk factors for malignancy !   to establish a system of evaluation for such tumours 2
  • 3. These are growths that are associated with the reproductive What are they? tract They include tumours arising from the female reproductive organs Although pertinent, breast tumours will not be discussed here 3
  • 4. Why the fuss? !   We all worry about cancer !   As such, all growths should be suspected cancerous !   It is our duty to confirm non-malignancy 4
  • 5. We all worry about cancer 5
  • 6. The objectives when a growth is discovered !   Most importantly, assess the probability of malignancy !   If malignancy is less likely, then assess the association with fertility !   Plan for management, most likely surgery 6
  • 8. Concepts on aetiology !   most premenopausal tumours are benign in origin !   malignancy can occur at all ages !   this risk increases with age !   postmenopausal women require aggressive evaluation !   cancer until proven otherwise 8
  • 9. General Causes !   Uterine fibroids !   Ovarian cysts ! Adenomyosis (older pt) •  Epithelial (arising from ovarian epithelium) !   Functional cysts - - Serous & mucinous occasionally grow large & symptomatic - most common !   Pregnancy •  Germ cell (from egg-producing cells) - In younger women •  Stromal ( from hormone producing cells) 9
  • 10. In the reproductive age group !   functional cysts (follicular or luteal) are most common !   usually small but may become larger - 10 cm !   frequently asymptomatic but can have dull, non- specific pain !   mostly due to intracystic haemorrhage ! tumours are rare - most common dermoid cysts & benign teratomas !   never forget pregnancy! 10
  • 11. nongynae causes Don t forget there s other stuff in the pelvis! Brown G. A gynecologic approach to evaluation of pelvic masses in women JAAPA 2012 11
  • 12. Symptoms 12
  • 13. The asymptomatic patient !   during a routine medical check up – physical exam, U/S scan etc !   from Pap smear results 13
  • 14. Abnormal Vaginal Bleeding !   usually occurs with tumours of lower tract !   endometrial, myometrial cervical etc.. !   fibroids are prone to heavy cyclical bleeding !   irregular, non-menstrual bleeding is more sinister ! postcoital bleed suggests intravaginal location !   polyps and cancers can occur, but infection is the most common cause !   ovarian tumours mostly bleed if cancerous, & only when advanced 14
  • 15. Abdominal pain !   ascertain if cyclical/dysmenorrhoea - more likely endometriosis or PID !   how long has it been there? !   If it has been there for a long time, is it progressively worsening? !   remember abdominal quadrants, !   usually, the pain will be overlying the offending organ 15
  • 16. Nonspecific symptoms !   bowel or urinary, these usually are sinister associations with the tumour !   endometriosis and/or adhesions may mimic these !   other symptoms that should be questioned include appetite & weight loss 16
  • 17. Infertility !   women in the reproductive age group must be questioned on this !   endometriosis & adenomyosis are among the most common causes of the pelvic mass !   the association of this symptom with a mass in most cases is due these conditions 17
  • 18. Ovarian cancer !   often manifests late !   abdominal or pelvic pain !   bloating !   abdominal distension !   other nonspecific symptoms 18
  • 19. Postmenopausal patient !   any tumour here warrants extensive investigation !   postmenopausal bleeding must be taken seriously !   commonest tumours at this age are ovarian !   may present only with nonspecific symptoms !   the pelvis should be looked at carefully 19
  • 20. SUMMARY OF ! TUMOUR! CLINICAL FEATURES! heavy cyclical menstruation, fibroids ! irregularly enlarged, mobile smooth uterus, usually non-tender nonspecific pelvic or abd pain, bloating, constitutional symptoms, ovarian cancer! fixed mass, may be irregular, firm, hard or soft, ascites may be present cyclical pain, dyspareunia, infertility, abnormal menstruation,soft-to-firm endometrioma! mass, usually fixed, lateral or central 20
  • 22. Inspection !   overall, the patient may look unwell !   she may be in extreme pain !   the abdomen may be distended, generally or asymmetrically !   the umbilicus may be deviated !   if acute, the abdomen may not move with respiration 22
  • 23. Palpation !   is the surface smooth or nodular? !   nodularity is not good !   is the mass fixed or mobile !   consistency - hard, firm or soft 23
  • 24. Can you go below the mass? !   important to feel if you can go below the mass if not, then it is most likely arising from the pelvis 24
  • 25. Ascites !   this is never a good sign !   you must know how to evaluate for shifting dullness 25
  • 26. Cervicovaginal inspection !   do not forget to assess below! 26
  • 27. An overview of cancers https://www.dropbox.com/s/whhmrateafmqus7/gynaecancers.pdf 27
  • 30. !   quite common at a later age, about 40s !   may be asymptomat ic, but most often cause heavy menstruatio n 30 Fibroids
  • 31. Endometriosis !   May present as either adenomyosis (uterine enlargement), !   a cyst or !   both. 31
  • 32. Adenomyosis Can be a diffuse or globular swelling K Endometrium-like tissue is found embedded within myometrium 32
  • 33. Funny things are seen This is a fibroid! 33
  • 34. The most common growth - fat! 34
  • 36. Role of ultrasound !   an essential tool for diagnosis - first Ix to be considered !   any mass must initially be scanned !   abdominal or transvaginal !   features to look for include composition of tumour, size, uni- or bilateral and presence of ascites 36
  • 37. Ultrasound TVS image produces greater resolution 37
  • 38. Blood tests !   General - assess cell lines for health & mx issues !   Tumour markers - limited diagnostic capability •  May be used as surveillance when increased !   Other tests depend on type of tumour 38
  • 39. Other imaging !   MRI & CT !   Laparoscopy - can be diagnostic, but better to be therapeutic 39
  • 40. summary 40
  • 41. Key points !   pelvic masses may have a benign or malignant aetiology !   the risk of malignancy is increased in postmenopausal women !   premenopausal masses are usually benign !   evaluation of premenopausal masses must include relationship with fertility !   U/S is an important evaluation tool for possibility of malignancy 41
  • 42. References !   Brown G. A gynecologic approach to evaluation of pelvic masses in women JAAPA 2012 !   Johnson BA. Evaluation of pelvic masses 2001 http://www.eric.vcu.edu/home/resources/whh/ VIIIeEVALUATION_PELVIC_MASSES.pdf 42
  • 43. Let s have coffee! 43