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HISTORY AND PHYSICAL EXAMINATION
IN
NEUROLOGY
NOTE
 Central Nervous System-Brain & Spinal
Cord
 Peripheral Nervous System-12 pairs of c
ranial nerves and the spinal and periphe
ral nerves.
 Most of the peripheral nerves contain bo
th motor and sensory fibers.
HISTORY
 Assess the cooperation of patient
 If not/ be it consciously or unconsciously,/ ta
ke history form attendants
 Try to get a clarification of the meaning of a
complaint
 Onset, evolution and course of the sympto
m
 Observe- speech, thought
 Some symptoms might not have sign—get
more information from history
PHYSICAL EXAMINATION
1. Mental status
2. Cranial nerve
3. Motor system
4. Reflexes
5. Sensory system
6. Special examination
I)MENTAL STATUS
 *LOC
 *Attention
 *Memory
 *Orientation
 Perception
 Thought process
 Thought content
 Insight
 Judgment
 Affect
 Mood
 *Language(speech)
 *Higher cognitive fun
ction
1.Level of consciousness*
 understand and respond to questions
 apply stimuli/ verbal, physical or painful/ and see resp
onse
 Conscious patient aware of himself & his environme
nt and is able to respond both to internal and external
stimuli
 Abnormality
 lethargy—drowsy, responds to quest’n and fall asleep
 obtundation– opens eye, responds slowly, confused a
nd low interest and alertness
 stupor– arouse from sleep with painful stimuli slow or
absent verbal response
 coma– unarousable
2. Orientation*
 Time
time of the day,date, month, year
 Place
residence, name of hospital, city, state
 Person
patients name, name of relative, name of colleagu
es
3. Attention*
 Digit span:- repeat a number of digits after you / forward
and backward/ or start with two and continue till the length the p
atient can’t repeat, tell loudly and slowly/ one digit per second
Normal-five forward/ four backward
 Serial seven:- subtract seven out of hundred note efort ,
speed, accuracy
Normal – finish in 1.5 min
 Spell backward:- Ask patient to spell a five lette
r word backward
Replace serial seven,
4. Memory*
 Remote /years/
birthdays, anniversaries, names of school attended
 Recent/minutes, hours to days/
ask events of the day
 New learning ability
tell three unrelated words and ask the patient to repeat
after three to five minutes
5. Insight and judgment
 INSIGHT:- Awareness of abnormality of the symp
tom, ask the patient what brings him to the hospital
 JUDGMENT:- Process of comparing and evalu
ating alternatives, assess patients response to family
situation, job, use of money, interpersonal conflicts
6. Perception/Thought
 Perception:- sensory awareness of objects & th
eir interrelationship in the environment
Abnormality-hallucination, illusion
 Thought content:- what people think about a
nd level of insight & judgment, Abnormality-delusion,
phobia, compulsion, depersonalization
 Thought process:- the logic, coherence, & re
levance of patients thinking as it leads to selected go
als
Abnormality– circumstancial, loosening of associatio
n, flights of ideas
7. Mood
 A sustained emotion affecting personal
view of the world
 Assess it during hx taking or ask directly
 Assess risk of suicide if pt is depressed
 Abnormalities—mood disorder
8. Higher cognitive function*
 information and vocabulary
ask about specific facts and assess the amount of informati
on he has Eg- the name of the president, prime minister etc
 Calculating ability
addition and multiplication
 Abstract thinking
interpretation of proverbs, similarities between objects
 Constructional ability
copy figures
Abnormalities in the above functions occur in patients with ment
al retardation, dementia, schizophrenia
9. SPEECH*
 Assess it during the interview
 Speech is mediated by the dominant hemisphere,
 assess
- spoken and written language
- character of speech/ articulation, fluency/
-if you find abnormality test different functions/na
ming, repetition, comprehension, writing/
 parietal- writing
 Parieto-occipital--- reading
 Frontal ---articulation
 Temporal---fluency, comprehension, repetition, writ
ing
Con’t
 Aphasia- fluency, comprehension, na
ming, repetition, reading, writing
- Anterior(Broca’s) aphasia-
fluency, articulation affected
- Posterior(Wernike’s) aphasia-
neologism, jargon
 Dyslexia-reading
 Dysgraphia-writing
II)CRANIAL NERVES 1-12
 All except 1 and 2 arise from the brain s
tem
 CN 1 & 2 are continuation of CN tissue
 Supply the head and neck / motor, sens
ory and autonomic/
 CN 1(Olfactory)
project to uncus and parahippo
Examine nasal canal
Assess smell
 CN 2(Optic)
Retina---optic nerve—optic chiasm--optic tract---lateral g
eniculate----calcarian cortex
Assess- visual acuity
visual field
others/ colour vision, visual localization, visual recog
nition/ if necessary
Visual acuity :- by Snellechart,special hand held ca
rd, count finger or light perception
Visual field
 confrontation
 Test one eye/ right with left and left with right/
 Sit at one meter distance and extend arm at eq
ual distance
 Assess every direction/up, down,right,lef
 perimeter
 CN 3(Occulomotor),4 (Abduscence)& 6(Trochl
ear)
Test extraocular mov’t
right eye
All except SO and LR supplied by CN3
levator palpebra Iris and ciliary muscle-Edinger Westpha
l nucleus
SR
IO
SO
IR
LR MR
 Conjugate eye movement integrate
d at brainstem
 Infranuclear-unilateral eye mov’t
strabismus- diplopia,dizziness
 Supranuclear-conjugate eye mov’
Lateral unilat-pontine paramdial reticular for
mation
Lateral bialteral-central pontine
Upward-central midbrain,inferior thalamic
Downward-medulla
 Cerebellar-Nystagmus
 Extrapyramidal-low interrupted purs
uit
 Pupil
size, shape, reaction to light and accomodati
on
afferent CN 2/bilateral/ and efferent CN3
abnormalities- Argyll Robertson pupil-NRL,R
A
-Tonic/Adie pupil-
CN 5(trigeminal) /ophthalmic,maxillary,
mandibular/
 sensory- face, upper teeth,nose, pharynx, tongue
 motor- Mastication muscles
 Parasympathetic- salivary and lacrimal gland
 CN 7(Facial)
 sensory- somatic auricle, taste anterior 2/3 of th
e tongue
 motor- muscles of facial expression
 Test-smile, eye closure,whistle,furrow,
 CN 8(Vestibulocochlear)
 cochlear –hearing
vestibular-- balance
Test hearing
 CN9,10,11(glossopharyngeal,vagus,accessa
ry)
 9-motor- pharyngeal,stylopharyngeal
taste-posterio 1/3
 10-motor-palate,pharynx,larynx
-parasympathetic-heart, viscera
 11- pure motor-sternocm, trapezius
See position of palate
Assess gag reflex, muscle/sternocm,trape
zius/
Hx-dysphagia, hoarseness of voice,dysart
hria
 CN 12(hypoglossal
◦ Motor to the tongue
MOTOR
 Involuntary movement
 Bulk
 Power-graded according to the research council scale
 Tone
 Reflex
 Coordination
 Gait
 Spastic hemiparetic
 Scissor
 Sensory ataxia
 Cerebellar ataxia
 Parkinsonian
 Bulk
 atrophy-LMNL
 Pseudohypertrophy- Musc dystrophy
 Power- Grade o-5
 Tone
 Hypotonic-LMNL, cerebellar
 Hypertonic- spastic- Corticospinal
-rigidity- extra pyramidal
-Paratonic/mitgehen
- gegenhalten/-bihemispheric lesion
Coordination
 RAM- observe speed, rhythm,smoothness
- hand
- finger
- thumb
 Point to point- observe smoothness and a
ccuracy
-finger to nose,
-heel to shin
 Stance
- Romberg’s sn 20-30s
- pronator drift 20-30s
 Gait
- assess the patients gait, tandem walk,
Reflex
 Grade 0-absent
1-low normal
2-average normal
3-brisk
4-associated with clonus
Ankle S1,2
Knee L2,3,4
Brachioradialis C5,6
Biceps C5,6
TricepsC6,7
SENSORY
Principles
 Compare symmetrically, distal &proximal
 Do it fast
 No need to do vibration and position proximal if distal is no
rmal
 Change pace and rhythm of examination
 Map the abnormality
Land marks :- C-3 neck, C-6 thumb, T-4 nipple, T-10 umbili
cus,
L-1 inguinal, L-4 Knee, L-5 Ankle, S3-5 peria
nal
 Modalities -pain &T-spinothalamic
-position& vibration-posterior column
-light touch-both
-recognition of shape, size, weight, form
- above + cortical
Special examination
Asterixis non rhythmic, brief flexion of the hand and
finger 1-2s
# Metabolic encephalopathy
Meningeal signs
Neck stiffness
Kernig’s
brudniski’s
Autonomic function
orthostatic change in BP,PR
Pupil rxn, sweating,
Minimental status assessment
 score out of 30,
 lower than 21 is associated with cognitive abnormality
& has 12 variables
- orientation to time and place and serial 7 score 5
- short term memory, learning ability and three stage
command 3
- naming and construction -2
- other variables assess speech/repetition, reading,
writing/ and another construction score 1
STUPOROUS OR COMATOUS PA
TIENT
 Respiration - hyperpnea- midbrain/pontine
- bradypnea-increase ICP
- Cheyne-stokes-hemispheric/dienceph
alo
- ataxic-medullary
 Pupil - unilateral D, -ve LR— uncal herniation
- midposition,-ve LR — midbrain
- miosis, +ve LR-- pontine
- fixed dilation-- diencephalon
- Horner’s syndrome– hypothal, thal
- Small pupil, brisk LR--- metabolic
- Small pupil, slugish LR--- Drug
 Ocular movement
Spontaneous
- conjugate deviation--- ipsilat hemisphere, contra
BS
- depression --- midbrain, metabolic
- dysconjugate--- CN 3 or6 affection
- ocular bobing low pon, cerebellar hematoma, hydr
ocephalus
 Reflex
- Oculocephalic
- Oculovestibular
 Corneal reflex absent in deep coma and drug induced c
oma/ light/
 Posture and muscle tone- Decerebrate/ decorticate
Thank you
Estrogen

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  • 1. HISTORY AND PHYSICAL EXAMINATION IN NEUROLOGY
  • 2. NOTE  Central Nervous System-Brain & Spinal Cord  Peripheral Nervous System-12 pairs of c ranial nerves and the spinal and periphe ral nerves.  Most of the peripheral nerves contain bo th motor and sensory fibers.
  • 3. HISTORY  Assess the cooperation of patient  If not/ be it consciously or unconsciously,/ ta ke history form attendants  Try to get a clarification of the meaning of a complaint  Onset, evolution and course of the sympto m  Observe- speech, thought  Some symptoms might not have sign—get more information from history
  • 4. PHYSICAL EXAMINATION 1. Mental status 2. Cranial nerve 3. Motor system 4. Reflexes 5. Sensory system 6. Special examination
  • 5. I)MENTAL STATUS  *LOC  *Attention  *Memory  *Orientation  Perception  Thought process  Thought content  Insight  Judgment  Affect  Mood  *Language(speech)  *Higher cognitive fun ction
  • 6. 1.Level of consciousness*  understand and respond to questions  apply stimuli/ verbal, physical or painful/ and see resp onse  Conscious patient aware of himself & his environme nt and is able to respond both to internal and external stimuli  Abnormality  lethargy—drowsy, responds to quest’n and fall asleep  obtundation– opens eye, responds slowly, confused a nd low interest and alertness  stupor– arouse from sleep with painful stimuli slow or absent verbal response  coma– unarousable
  • 7. 2. Orientation*  Time time of the day,date, month, year  Place residence, name of hospital, city, state  Person patients name, name of relative, name of colleagu es
  • 8. 3. Attention*  Digit span:- repeat a number of digits after you / forward and backward/ or start with two and continue till the length the p atient can’t repeat, tell loudly and slowly/ one digit per second Normal-five forward/ four backward  Serial seven:- subtract seven out of hundred note efort , speed, accuracy Normal – finish in 1.5 min  Spell backward:- Ask patient to spell a five lette r word backward Replace serial seven,
  • 9. 4. Memory*  Remote /years/ birthdays, anniversaries, names of school attended  Recent/minutes, hours to days/ ask events of the day  New learning ability tell three unrelated words and ask the patient to repeat after three to five minutes
  • 10. 5. Insight and judgment  INSIGHT:- Awareness of abnormality of the symp tom, ask the patient what brings him to the hospital  JUDGMENT:- Process of comparing and evalu ating alternatives, assess patients response to family situation, job, use of money, interpersonal conflicts
  • 11. 6. Perception/Thought  Perception:- sensory awareness of objects & th eir interrelationship in the environment Abnormality-hallucination, illusion  Thought content:- what people think about a nd level of insight & judgment, Abnormality-delusion, phobia, compulsion, depersonalization  Thought process:- the logic, coherence, & re levance of patients thinking as it leads to selected go als Abnormality– circumstancial, loosening of associatio n, flights of ideas
  • 12. 7. Mood  A sustained emotion affecting personal view of the world  Assess it during hx taking or ask directly  Assess risk of suicide if pt is depressed  Abnormalities—mood disorder
  • 13. 8. Higher cognitive function*  information and vocabulary ask about specific facts and assess the amount of informati on he has Eg- the name of the president, prime minister etc  Calculating ability addition and multiplication  Abstract thinking interpretation of proverbs, similarities between objects  Constructional ability copy figures Abnormalities in the above functions occur in patients with ment al retardation, dementia, schizophrenia
  • 14. 9. SPEECH*  Assess it during the interview  Speech is mediated by the dominant hemisphere,  assess - spoken and written language - character of speech/ articulation, fluency/ -if you find abnormality test different functions/na ming, repetition, comprehension, writing/  parietal- writing  Parieto-occipital--- reading  Frontal ---articulation  Temporal---fluency, comprehension, repetition, writ ing
  • 15. Con’t  Aphasia- fluency, comprehension, na ming, repetition, reading, writing - Anterior(Broca’s) aphasia- fluency, articulation affected - Posterior(Wernike’s) aphasia- neologism, jargon  Dyslexia-reading  Dysgraphia-writing
  • 16. II)CRANIAL NERVES 1-12  All except 1 and 2 arise from the brain s tem  CN 1 & 2 are continuation of CN tissue  Supply the head and neck / motor, sens ory and autonomic/
  • 17.  CN 1(Olfactory) project to uncus and parahippo Examine nasal canal Assess smell  CN 2(Optic) Retina---optic nerve—optic chiasm--optic tract---lateral g eniculate----calcarian cortex Assess- visual acuity visual field others/ colour vision, visual localization, visual recog nition/ if necessary Visual acuity :- by Snellechart,special hand held ca rd, count finger or light perception
  • 18. Visual field  confrontation  Test one eye/ right with left and left with right/  Sit at one meter distance and extend arm at eq ual distance  Assess every direction/up, down,right,lef  perimeter
  • 19.  CN 3(Occulomotor),4 (Abduscence)& 6(Trochl ear) Test extraocular mov’t right eye All except SO and LR supplied by CN3 levator palpebra Iris and ciliary muscle-Edinger Westpha l nucleus SR IO SO IR LR MR
  • 20.
  • 21.  Conjugate eye movement integrate d at brainstem  Infranuclear-unilateral eye mov’t strabismus- diplopia,dizziness  Supranuclear-conjugate eye mov’ Lateral unilat-pontine paramdial reticular for mation Lateral bialteral-central pontine Upward-central midbrain,inferior thalamic Downward-medulla  Cerebellar-Nystagmus  Extrapyramidal-low interrupted purs uit
  • 22.  Pupil size, shape, reaction to light and accomodati on afferent CN 2/bilateral/ and efferent CN3 abnormalities- Argyll Robertson pupil-NRL,R A -Tonic/Adie pupil- CN 5(trigeminal) /ophthalmic,maxillary, mandibular/  sensory- face, upper teeth,nose, pharynx, tongue  motor- Mastication muscles  Parasympathetic- salivary and lacrimal gland
  • 23.  CN 7(Facial)  sensory- somatic auricle, taste anterior 2/3 of th e tongue  motor- muscles of facial expression  Test-smile, eye closure,whistle,furrow,  CN 8(Vestibulocochlear)  cochlear –hearing vestibular-- balance Test hearing
  • 24.  CN9,10,11(glossopharyngeal,vagus,accessa ry)  9-motor- pharyngeal,stylopharyngeal taste-posterio 1/3  10-motor-palate,pharynx,larynx -parasympathetic-heart, viscera  11- pure motor-sternocm, trapezius See position of palate Assess gag reflex, muscle/sternocm,trape zius/ Hx-dysphagia, hoarseness of voice,dysart hria  CN 12(hypoglossal ◦ Motor to the tongue
  • 25. MOTOR  Involuntary movement  Bulk  Power-graded according to the research council scale  Tone  Reflex  Coordination
  • 26.  Gait  Spastic hemiparetic  Scissor  Sensory ataxia  Cerebellar ataxia  Parkinsonian
  • 27.  Bulk  atrophy-LMNL  Pseudohypertrophy- Musc dystrophy  Power- Grade o-5  Tone  Hypotonic-LMNL, cerebellar  Hypertonic- spastic- Corticospinal -rigidity- extra pyramidal -Paratonic/mitgehen - gegenhalten/-bihemispheric lesion
  • 28. Coordination  RAM- observe speed, rhythm,smoothness - hand - finger - thumb  Point to point- observe smoothness and a ccuracy -finger to nose, -heel to shin  Stance - Romberg’s sn 20-30s - pronator drift 20-30s  Gait - assess the patients gait, tandem walk,
  • 29. Reflex  Grade 0-absent 1-low normal 2-average normal 3-brisk 4-associated with clonus Ankle S1,2 Knee L2,3,4 Brachioradialis C5,6 Biceps C5,6 TricepsC6,7
  • 30. SENSORY Principles  Compare symmetrically, distal &proximal  Do it fast  No need to do vibration and position proximal if distal is no rmal  Change pace and rhythm of examination  Map the abnormality Land marks :- C-3 neck, C-6 thumb, T-4 nipple, T-10 umbili cus, L-1 inguinal, L-4 Knee, L-5 Ankle, S3-5 peria nal  Modalities -pain &T-spinothalamic -position& vibration-posterior column -light touch-both -recognition of shape, size, weight, form - above + cortical
  • 31. Special examination Asterixis non rhythmic, brief flexion of the hand and finger 1-2s # Metabolic encephalopathy Meningeal signs Neck stiffness Kernig’s brudniski’s Autonomic function orthostatic change in BP,PR Pupil rxn, sweating,
  • 32. Minimental status assessment  score out of 30,  lower than 21 is associated with cognitive abnormality & has 12 variables - orientation to time and place and serial 7 score 5 - short term memory, learning ability and three stage command 3 - naming and construction -2 - other variables assess speech/repetition, reading, writing/ and another construction score 1
  • 33. STUPOROUS OR COMATOUS PA TIENT  Respiration - hyperpnea- midbrain/pontine - bradypnea-increase ICP - Cheyne-stokes-hemispheric/dienceph alo - ataxic-medullary  Pupil - unilateral D, -ve LR— uncal herniation - midposition,-ve LR — midbrain - miosis, +ve LR-- pontine - fixed dilation-- diencephalon - Horner’s syndrome– hypothal, thal - Small pupil, brisk LR--- metabolic - Small pupil, slugish LR--- Drug
  • 34.  Ocular movement Spontaneous - conjugate deviation--- ipsilat hemisphere, contra BS - depression --- midbrain, metabolic - dysconjugate--- CN 3 or6 affection - ocular bobing low pon, cerebellar hematoma, hydr ocephalus  Reflex - Oculocephalic - Oculovestibular  Corneal reflex absent in deep coma and drug induced c oma/ light/  Posture and muscle tone- Decerebrate/ decorticate