Esophagectomy is a surgical procedure that involves the complete or partial removal of the esophagus, often used to treat advanced esophageal cancer, Barrett’s esophagus, or various noncancerous conditions. The surgery can be performed through several methods including transhiatal, transthoracic, thoracoabdominal, or minimally invasive laparoscopic techniques, with the extent of the removal varying based on specific factors. Complications can include bleeding, infections, voice changes, and swallowing difficulties, with relative contraindications being advanced age and comorbid illnesses.