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ERADICATION OF POLIOMYELITIS 
RISHI KASHYAP
WHY POLIO IS A CANDIDATE FOR ERADICATION 
? 
• MAN IS THE ONLY RESERVIOR 
• NO LONG TERM CARRIER STATE 
• ROUTE OF TRANSMISSION IS FAECO-ORAL 
• HALF LIFE OF EXCRETED VIRUS IN SEWAGE 
SAMPLE IN TROPICAL CLIMATE LIKE INDIA IS 
48 HOURS. 
• POTENT AND EFFECTIVE VACCINE.
Strategies for polio eradication in 
India 
 Conduct Pulse Polio Immunization days every 
year until poliomyelitis is eradicated. 
 Sustained high levels of routine immunization 
coverage. 
 Monitor OPV coverage at district level and below. 
Improve surveillance capable of detecting all 
cases of AFP due to polio and non polio etiology.
• Ensure rapid case investigation, including the 
collection of stool samples for virus isolation. 
• Arrange follow-up of all cases of AFP at 60 
days to check for residual paralysis. 
• Conduct outbreak control for cases confirmed 
or suspected to be poliomyelitis to stop 
transmission.
• Even a single case is treated as an outbreak 
and preventive measures are initiated. 
• The complete and timely reporting of cases is 
an important element for the eradication of 
poliomyelitis.
Line listing of cases 
• Line listing of reported cases was started in 
1989 to check for duplication of case. 
• Line listing of cases made it possible to take 
appropriate follow-up action from where the 
cases had been reported. 
• The line lists have also provided useful 
epidemiological data for programme 
purposes.
• All cases of acute flaccid paralysis must be 
reported immediately to the chief medical 
officer/district immunization officer with the 
following details: 
• Name, age and sex of the patient. 
• Father’s name and complete address. 
• Vaccination status 
• Date of onset of paralysis and data for 
reporting.
• Clinical diagnosis. 
• Doctor’s name, address and phone number.
Mopping Up 
• Mopping up activities are usually the last in 
polio eradication. 
• It involves door-to-door immunization in high 
risk districts, where wild polio virus is known 
or suspected to be still circulating. 
• This strategy is being implemented in India.
Pulse Polio Immunization 
• The term “pulse” has been used to describe 
this sudden, simultaneous, mass 
administration of OPV on a single day to all 
children 0-5 years of age regardless to 
previous immunization. 
• PPIs occurs as two rounds about 4 to 6 weeks 
apart during low transmission season of polio, 
i.e. between November to February.
• In India, the peak transmission is from June to 
September. 
• An important improvement in PPI during 1998 
has been the use of vaccine vial monitor. 
• When the color of the white square becomes 
blue like that of surrounding circle, the vaccine 
should be considered ineffective.
STEPS INVOLVED 
Setting up of booths in all parts of the country 
Initialising walk-in cold rooms, freezer rooms, deep freezers, ice-lined refrigerators 
and cold boxes for ensuring steady supply of vaccine to booths. 
Arranging employees, volunteers and vaccines. 
Ensuring vaccine vial monitor on each vaccine vial. 
Immunising children with OPV on National Immunisation Days. 
Identifying missing children from immunisation process. 
Surveillance of efficacy. 
13
ACUTE FLACCID PARALYSIS 
Surveillance
A.F.P. 
DEFINITION : 
Sudden onset of 
weakness of a limb or paralysis 
over a period of 15 days 
in a patient less 15 years of age .
WHAT IS SURVEILLANCE ? 
• IT IS A CONTINOUS SCRUTINY 
• OF ALL ASPECTS OF OCCURRENCE & SPREAD OF 
DISEASE 
• THAT ARE PERTINENT TO EFFECTIVE CONTROL. 
• SURVEILLANCE INCLUDES 
1. COLLECTION OF DATA 
2. ANALYSIS OF DATA 
3. INTERPRETATION OF DATA 
4. DISTRIBUTION OF RELEVANT DATA SO THAT 
NECESSARY ACTION CAN BE TAKEN
The AFP Surveillance System 
Community 
Hospitals 
Clinics 
Investigation 
Non-Polio AFP Polio AFP
GOAL OF AFP SURVEILLANCE 
• IDENTIFICATION OF ALL RESERVOIRS OF 
CIRCULATING WILD POLIO VIRUS 
• ( THAT COULD BE POLIO ) BY DOCUMENTING 
ALL SUCH CASES,IT IS POSSIBLE TO SHOW 
THAT NONE OF THESE “POLIO-LIKE” CASES 
WERE CAUSED BY THE POLIO VIRUS,AND 
THAT POLIO IS NO LONGER PRESENT OR 
EXISTING.
WHY AFP SURVEILLANCE INSTEAD OF 
POLIO SURVEILLANCE ? 
• SURVEILLANCE OF A POLIO CASE ALONE IS NOT 
SUFFICIENT BECAUSE IT IS IMPOSSIBLE TO 
PRECISELY IDENTIFY ALL CASES OF POLIO CLINICALLY 
DUE TO CONFUSING AND AMBIGUOUS CLINICAL 
SIGNS AND VARIABLE CLINICAL KNOWLEDGE & 
SKILLS OF DOCTOR. 
• CLINICALLY POLIO IN ACUTE STAGE, IS DIFFICULT TO 
DISTINGUISH FROM OTHER CAUSES OF ACUTE 
ONSET OF FLACCID PARALYSIS.
WHAT TO REPORT 
• Any Case of Acute Flaccid Paralysis < 15 Yrs 
age. 
• It May be Monoplegia, Paraplegia, 
Hemiplegia,Facial Palsy, or Any Transient 
weakness. 
• Any case of Suspected Polio Clinically 
Irrespective of any age.
WHAT IS NOT AFP ? 
• TRAUMA 
• ISOLATED FACIAL NERVE PALSY 
• HYPOKALAEMIA 
• ACUTE RHEUMATIC FEVER 
• CONGENITAL FLACCID PARALYSIS
CONDITIONS SOMETIMES 
PRESENTING WITH AFP 
• TUMOR 
• ENCEPHALITIS 
• HYPOKALEMIC PARALYSIS [ DUE TO LOW 
SERUM POTASSIUM USUALLY REVERSIBLE ] 
• POTT’s DISEASE 
• TB MENINGITIS 
• OSTEOMYELITIS
Last Reported Polio Cases 
Polio Virus Type Date of last case Location 
P1 13 January 2011 Howrah (Panchla), 
WB 
P2 24 October 1999 Aligarh, UP 
P3 22 October 2010 Pakur , Jharkhand 
Source: WHO 23
• In 2012, WHO removed India from a list of 
countries with active endemic wild polio 
transmission after it passed one year without 
registering any new cases. 
• Completing three full years without reporting 
any case of polio, India celebrated a landmark 
achievement in public health on 11 February 
2014 – the victory over polio.
Thank you

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Eradication of polio(India)

  • 2. WHY POLIO IS A CANDIDATE FOR ERADICATION ? • MAN IS THE ONLY RESERVIOR • NO LONG TERM CARRIER STATE • ROUTE OF TRANSMISSION IS FAECO-ORAL • HALF LIFE OF EXCRETED VIRUS IN SEWAGE SAMPLE IN TROPICAL CLIMATE LIKE INDIA IS 48 HOURS. • POTENT AND EFFECTIVE VACCINE.
  • 3. Strategies for polio eradication in India  Conduct Pulse Polio Immunization days every year until poliomyelitis is eradicated.  Sustained high levels of routine immunization coverage.  Monitor OPV coverage at district level and below. Improve surveillance capable of detecting all cases of AFP due to polio and non polio etiology.
  • 4. • Ensure rapid case investigation, including the collection of stool samples for virus isolation. • Arrange follow-up of all cases of AFP at 60 days to check for residual paralysis. • Conduct outbreak control for cases confirmed or suspected to be poliomyelitis to stop transmission.
  • 5. • Even a single case is treated as an outbreak and preventive measures are initiated. • The complete and timely reporting of cases is an important element for the eradication of poliomyelitis.
  • 6. Line listing of cases • Line listing of reported cases was started in 1989 to check for duplication of case. • Line listing of cases made it possible to take appropriate follow-up action from where the cases had been reported. • The line lists have also provided useful epidemiological data for programme purposes.
  • 7. • All cases of acute flaccid paralysis must be reported immediately to the chief medical officer/district immunization officer with the following details: • Name, age and sex of the patient. • Father’s name and complete address. • Vaccination status • Date of onset of paralysis and data for reporting.
  • 8. • Clinical diagnosis. • Doctor’s name, address and phone number.
  • 9. Mopping Up • Mopping up activities are usually the last in polio eradication. • It involves door-to-door immunization in high risk districts, where wild polio virus is known or suspected to be still circulating. • This strategy is being implemented in India.
  • 10. Pulse Polio Immunization • The term “pulse” has been used to describe this sudden, simultaneous, mass administration of OPV on a single day to all children 0-5 years of age regardless to previous immunization. • PPIs occurs as two rounds about 4 to 6 weeks apart during low transmission season of polio, i.e. between November to February.
  • 11. • In India, the peak transmission is from June to September. • An important improvement in PPI during 1998 has been the use of vaccine vial monitor. • When the color of the white square becomes blue like that of surrounding circle, the vaccine should be considered ineffective.
  • 12.
  • 13. STEPS INVOLVED Setting up of booths in all parts of the country Initialising walk-in cold rooms, freezer rooms, deep freezers, ice-lined refrigerators and cold boxes for ensuring steady supply of vaccine to booths. Arranging employees, volunteers and vaccines. Ensuring vaccine vial monitor on each vaccine vial. Immunising children with OPV on National Immunisation Days. Identifying missing children from immunisation process. Surveillance of efficacy. 13
  • 14. ACUTE FLACCID PARALYSIS Surveillance
  • 15. A.F.P. DEFINITION : Sudden onset of weakness of a limb or paralysis over a period of 15 days in a patient less 15 years of age .
  • 16. WHAT IS SURVEILLANCE ? • IT IS A CONTINOUS SCRUTINY • OF ALL ASPECTS OF OCCURRENCE & SPREAD OF DISEASE • THAT ARE PERTINENT TO EFFECTIVE CONTROL. • SURVEILLANCE INCLUDES 1. COLLECTION OF DATA 2. ANALYSIS OF DATA 3. INTERPRETATION OF DATA 4. DISTRIBUTION OF RELEVANT DATA SO THAT NECESSARY ACTION CAN BE TAKEN
  • 17. The AFP Surveillance System Community Hospitals Clinics Investigation Non-Polio AFP Polio AFP
  • 18. GOAL OF AFP SURVEILLANCE • IDENTIFICATION OF ALL RESERVOIRS OF CIRCULATING WILD POLIO VIRUS • ( THAT COULD BE POLIO ) BY DOCUMENTING ALL SUCH CASES,IT IS POSSIBLE TO SHOW THAT NONE OF THESE “POLIO-LIKE” CASES WERE CAUSED BY THE POLIO VIRUS,AND THAT POLIO IS NO LONGER PRESENT OR EXISTING.
  • 19. WHY AFP SURVEILLANCE INSTEAD OF POLIO SURVEILLANCE ? • SURVEILLANCE OF A POLIO CASE ALONE IS NOT SUFFICIENT BECAUSE IT IS IMPOSSIBLE TO PRECISELY IDENTIFY ALL CASES OF POLIO CLINICALLY DUE TO CONFUSING AND AMBIGUOUS CLINICAL SIGNS AND VARIABLE CLINICAL KNOWLEDGE & SKILLS OF DOCTOR. • CLINICALLY POLIO IN ACUTE STAGE, IS DIFFICULT TO DISTINGUISH FROM OTHER CAUSES OF ACUTE ONSET OF FLACCID PARALYSIS.
  • 20. WHAT TO REPORT • Any Case of Acute Flaccid Paralysis < 15 Yrs age. • It May be Monoplegia, Paraplegia, Hemiplegia,Facial Palsy, or Any Transient weakness. • Any case of Suspected Polio Clinically Irrespective of any age.
  • 21. WHAT IS NOT AFP ? • TRAUMA • ISOLATED FACIAL NERVE PALSY • HYPOKALAEMIA • ACUTE RHEUMATIC FEVER • CONGENITAL FLACCID PARALYSIS
  • 22. CONDITIONS SOMETIMES PRESENTING WITH AFP • TUMOR • ENCEPHALITIS • HYPOKALEMIC PARALYSIS [ DUE TO LOW SERUM POTASSIUM USUALLY REVERSIBLE ] • POTT’s DISEASE • TB MENINGITIS • OSTEOMYELITIS
  • 23. Last Reported Polio Cases Polio Virus Type Date of last case Location P1 13 January 2011 Howrah (Panchla), WB P2 24 October 1999 Aligarh, UP P3 22 October 2010 Pakur , Jharkhand Source: WHO 23
  • 24. • In 2012, WHO removed India from a list of countries with active endemic wild polio transmission after it passed one year without registering any new cases. • Completing three full years without reporting any case of polio, India celebrated a landmark achievement in public health on 11 February 2014 – the victory over polio.