1 Aisling English (Final Year Pharmacy Undergraduate Student) 2 Dr Zena Moore (Supervisor)
1 School of Pharmacy, 2Faculty of Nursing & Midwifery , 1,2Royal College of Surgeons in Ireland, Dublin 2, Ireland
From Medical perspective, patients who don’t comply with doctors orders are usually seen as deviant and deviance needs correction
But many chronically view their behavior differently, as matter of self regulation
American Sociologist Peter Conrad
A good working atmosphere and healthy moral climate makes therapeutic efforts more easy in all Institutions
Acne vulgaris is a common chronic skin disease involving blockage and/or inflammation of pilosebaceous units. Acne can present as non-inflammatory lesions, inflammatory lesions, or a mixture of both, affecting mostly the face but also the back and chest. Variable rates of relapse after oral isotretinoin treatment have been published. This could be explained by different reasons; one of them is the lack of consensus about the definition of acne relapse after treatment. The objective of this review is to summarize all the different defi nitions of acne relapse proposed in the literature, in order to fi nd a more reproducible and consistent characterization. This may become a useful tool that allows to compare the results obtained in future studies performed on acne relapses. As acne vulgaris is a dynamic entity that is notoriously difficult to assess over time, quantitative scales would be more indicated to evaluate its severity. In addition, the relapses after treatment are in correlation with the maintenance treatment phase. In this review, we also discuss the concepts of acute and maintenance phase of acne treatment. As the maintenance phase of treatment is a more recent concept, we consider necessary to review the features of this phase such as implantation time, treatment type, duration and efficacy. More studies, with a standardized relapse defi nition, are needed in order to determine effi cacy rates and optimal duration of this phase. In conclusion, this review aims to highlight the need for a valid and reliable defi nition of acne relapse, especially for its use in research, but also highly valuable in daily clinical practice.
From Medical perspective, patients who don’t comply with doctors orders are usually seen as deviant and deviance needs correction
But many chronically view their behavior differently, as matter of self regulation
American Sociologist Peter Conrad
A good working atmosphere and healthy moral climate makes therapeutic efforts more easy in all Institutions
Acne vulgaris is a common chronic skin disease involving blockage and/or inflammation of pilosebaceous units. Acne can present as non-inflammatory lesions, inflammatory lesions, or a mixture of both, affecting mostly the face but also the back and chest. Variable rates of relapse after oral isotretinoin treatment have been published. This could be explained by different reasons; one of them is the lack of consensus about the definition of acne relapse after treatment. The objective of this review is to summarize all the different defi nitions of acne relapse proposed in the literature, in order to fi nd a more reproducible and consistent characterization. This may become a useful tool that allows to compare the results obtained in future studies performed on acne relapses. As acne vulgaris is a dynamic entity that is notoriously difficult to assess over time, quantitative scales would be more indicated to evaluate its severity. In addition, the relapses after treatment are in correlation with the maintenance treatment phase. In this review, we also discuss the concepts of acute and maintenance phase of acne treatment. As the maintenance phase of treatment is a more recent concept, we consider necessary to review the features of this phase such as implantation time, treatment type, duration and efficacy. More studies, with a standardized relapse defi nition, are needed in order to determine effi cacy rates and optimal duration of this phase. In conclusion, this review aims to highlight the need for a valid and reliable defi nition of acne relapse, especially for its use in research, but also highly valuable in daily clinical practice.
Nursing research proposal topics you can use to find the best topics that suits your needs perfectly http://www.phdresearchproposal.org/nursing-research-proposal-topics/
This is the presentation Victor Montori (KER UNIT, Healthcare Delivery Research Program, Mayo Clinic) gave at the Normalization Process Theory symposium at King's Fund, London, UK on October 22, 2010.
A Study on Patient Satisfaction towards Cancer Hospitalijtsrd
A cancer diagnosis places considerable stress on patients and their families. They find themselves discomfort with the strange health system making serious decisions with long term consequences living with uncertainness about the nature, cause and indefinite progress of the disease living with a disrupted family, work, social life and facing the possibility of becoming increasingly dependent on others. Dhivya. S | Harshath. S "A Study on Patient Satisfaction towards Cancer Hospital" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-6 , October 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29274.pdf Paper URL: https://www.ijtsrd.com/management/consumer-behaviour/29274/a-study-on-patient-satisfaction-towards-cancer-hospital/dhivya-s
The impact of nursing leadership on patient safety outcomes: a systematic reviewanne spencer
Lisa Abraham is undertaking her MSc in Nursing in Advance Leadership, her presentation was given at the Nursing Showcase in St Mary's Campus in March 2016.
"Meet me Alone, I'm real, let's talk to meet now.
I'm on-line presently ~>>>>>>> Aloneme01@outlook.com <<<<<<<<<<
don't worry, no demand any cc charge."
Nursing research proposal topics you can use to find the best topics that suits your needs perfectly http://www.phdresearchproposal.org/nursing-research-proposal-topics/
This is the presentation Victor Montori (KER UNIT, Healthcare Delivery Research Program, Mayo Clinic) gave at the Normalization Process Theory symposium at King's Fund, London, UK on October 22, 2010.
A Study on Patient Satisfaction towards Cancer Hospitalijtsrd
A cancer diagnosis places considerable stress on patients and their families. They find themselves discomfort with the strange health system making serious decisions with long term consequences living with uncertainness about the nature, cause and indefinite progress of the disease living with a disrupted family, work, social life and facing the possibility of becoming increasingly dependent on others. Dhivya. S | Harshath. S "A Study on Patient Satisfaction towards Cancer Hospital" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-6 , October 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29274.pdf Paper URL: https://www.ijtsrd.com/management/consumer-behaviour/29274/a-study-on-patient-satisfaction-towards-cancer-hospital/dhivya-s
The impact of nursing leadership on patient safety outcomes: a systematic reviewanne spencer
Lisa Abraham is undertaking her MSc in Nursing in Advance Leadership, her presentation was given at the Nursing Showcase in St Mary's Campus in March 2016.
"Meet me Alone, I'm real, let's talk to meet now.
I'm on-line presently ~>>>>>>> Aloneme01@outlook.com <<<<<<<<<<
don't worry, no demand any cc charge."
InterTech is a Qatar contractor companyMaxim Gavrik
InterTech is a Qatar contractor company, which provides a full range of services for design, construction, installation, commissioning and start-up of the MEP systems in the buildings and structures under industrial, commercial and civil construction.
Running head STRATEGIC PLAN FOR CHANGE1STRATEGIC PLAN FOR.docxtoltonkendal
Running head: STRATEGIC PLAN FOR CHANGE
1
STRATEGIC PLAN FOR CHANGE
2
Strategic Plan for Change
Jennifer Zimmerman
Walden University- NURS 6201
December 29, 2017
Improving Patient Experience who are Undergoing Chemotherapy from an Outpatient setting to an Inpatient Setting
1.
Introduction and Statement of the Problem
1.1.
What is the problem?
Outpatient chemotherapy sessions are sufficient in most organizations, especially for those receiving curative intent chemotherapy (Davidoff et al. 2013). The patients who meet the set criteria end up receiving supportive care post induction chemotherapy, as well as different cycles as other outpatients. Outpatient management can be made safe and the transition to inpatient more efficient, which is considered a challenge for most healthcare organizations. The problem at hand in this section has been adequately analyzed, which involves the transition of patients receiving chemotherapy from outpatient to inpatient in healthcare facilities.
1.2.
Why is it important enough to warrant a change?
Outpatient care especially for most patient has become a familiar concept that is driven by increased healthcare costs and more so, the increased demand for existing inpatient resources in different organizations (Joana et al. 1987). Improved supportive care in inpatient is also another reason for the need to embrace the transition, and patient wishes to spend the least amount of time, especially in waiting for service delivery in the outpatient setting. With these concepts in mind, it is important enough to warrant a change. Patient satisfaction ought not to be ignored in different healthcare organizations. There is a need to, therefore, be on the forefront in enhancing adequate care, and embracing inpatient plans for the chronically ill patients.
1.2.1.
Scholarly Reference #1
Joana, L., Mary, H., Alan, M., Andrew, B., & Steven, C., (1987). Case Mix and Changes in inpatient and outpatient chemotherapy. PubMed 8(4): 65-71.
In most healthcare settings, the therapy provided in outpatient has been associated with substantial tumors, chemotherapy involving high doses, and then followed by autologous stem cell transplantation. Outpatient administration of consolidation cycles has been reported, which emphasizes the major problem in this scholarly soured. According to the authors, the transition to inpatient to outpatient care should be considered and priority to solve the efficiency problems at hand.
1.2.2.
Scholarly Reference #2
Hayes, J. (2014). The theory and practice of change management. Palgrave Macmillan.
This source deals with theory and practice of change management. Change management is an adequate practice in the healthcare setting. There is a need for all healthcare organizations to be at the forefront to ensure that healthcare, both inpatient and outpatient are realized. The source provides and explains outpatient inefficiency for chronic patients as the worst problem in the medical profession. Th ...
Nursing Evidence Based Practice PPT for BSN Nurses.
This ppt assess effectiveness of using NPWT for DFUs with providing highest level of evidence. DFUs are a prevalent issue in many countries and is treated via dressings which take a long time to heal but utilizing this method will certainly make the recovery faster.
Patients' satisfaction towards doctors treatmentmustafa farooqi
The mood of the care recipient to see if the impression (expectations) of service are met by the patient may be defined as patient satisfaction. The current perspective on service efficiency tends to be that patient treatment meets public standards and requirements in terms of interpersonal support as well as professional assistance. (Hardy et al. 1996). For various reasons, customer satisfactions in the healthcare industry have been investigated. First it was important to decide on the extent and the degree to which patient care seekers, the meeting of drugs criteria and the continuous use of these services have effect, satisfaction as a quality of service metric, as well as allowing doctors and health services to better appreciate and use the input of the patient. (Ong et al. 2000). Consumer satisfaction with healthcare services is a multi-panel term that refers to the core facets of treatment and suppliers, while PS medical services with the quality enhancement systems from the patient context, full control of quality and the intended outcomes of services are considered to be of primary importance (Janicijevic et al. 2013). The Pakistani health system is being changed somewhat and there are wonderful scope for applying standard of services to health care. Patients in Pakistan now have access to increased quality health care. Obviously, the staff and staff are the most important winners of a successful health care environment of every community sector framework (Bakari et al. 2019). The medical clinic of today's study is the product of a long and complicated war of civilization to quantify produce and study and to give thought to the thoughtful (Fullman et al. 2017).
Patients' satisfaction towards doctors treatmentmustafa farooqi
The mood of the care recipient to see if the impression (expectations) of service are met by the patient may be defined as patient satisfaction. The current perspective on service efficiency tends to be that patient treatment meets public standards and requirements in terms of interpersonal support as well as professional assistance. (Hardy et al. 1996).
For various reasons, customer satisfactions in the healthcare industry have been investigated. First it was important to decide on the extent and the degree to which patient care seekers, the meeting of drugs criteria and the continuous use of these services have effect, satisfaction as a quality of service metric, as well as allowing doctors and health services to better appreciate and use the input of the patient. (Ong et al. 2000).
Consumer satisfaction with healthcare services is a multi-panel term that refers to the core facets of treatment and suppliers, while PS medical services with the quality enhancement systems from the patient context, full control of quality and the intended outcomes of services are considered to be of primary importance (Janicijevic et al. 2013).
The Pakistani health system is being changed somewhat and there are wonderful scope for applying standard of services to health care. Patients in Pakistan now have access to increased quality health care. Obviously, the staff and staff are the most important winners of a successful health care environment of every community sector framework (Bakari et al. 2019).
The medical clinic of today's study is the product of a long and complicated war of civilization to quantify produce and study and to give thought to the thoughtful (Fullman et al. 2017).
Advocating Through PolicyAs noted by Dr. Stanley and Dr. Wlatashiadegale
Advocating Through Policy
As noted by Dr. Stanley and Dr. White in this week’s media presentation, professional nurses should be engaging in advocacy efforts to improve health and nursing practice through involvement in the policy process at the institutional, local, state, or federal levels. This array of possibilities for involvement provides opportunities for all nurses, regardless of time, or other possible constraints. Successful policy making is a collaborative effort, and one that commands mutual respect from all involved. Your involvement in policy making can lead to expanded opportunities as both a nurse leader and as a respected member of an interprofessional health care team.
Note
: This Discussion provides a forum for discussing advocacy opportunities and honing your presentation skills in a small group setting.
To prepare:
Reflect on the insights offered by Dr. Stanley and Dr. White on engaging in advocacy through the policy process.
Identify a practice issue that is of interest to you and that could benefit from advocacy efforts through the policy process.
Consider the stakeholders and any special interest or professional organizations that would support your issue.
Develop a short, yet persuasive PowerPoint (up to 3 slides IN APA FORMAT) as follows:
1) Identify the practice issue that would benefit from being addressed through the policy process
2) Represent the key stakeholders (i.e. use graphical images when possible)
3) Propose one strategy for how a nurse could advocate for this issue
The PowerPoint should be succinct, visually appealing, and effective.
By Tuesday 5/8/18 6pm
Post
your PowerPoint presentation.
Required Readings
Bodenheimer, T., & Grumbach, K. (2016).
Understanding health policy: A clinical approach
(7th ed.). New York, NY: McGraw-Hill Medical.
Chapter 17, “Conclusion: Tensions and Challenges”
This chapter concludes with final thoughts on the challenge of providing quality health care and controlling health care costs. The solution is likely to be resolved only by a collaborative approach, involving all health care stakeholders, and by health professionals taking the lead.
Howard, J., Levy, F., Mareiniss, D. P., Craven, C. K., McCarthy, M., Epstein-Peterson, Z. D., & et al. (2010). New legal protections for reporting patient errors under the Patient Safety and Quality Improvement Act: A review of the medical literature and analysis.
Journal of Patient Safety, 6
(3), 147-152
.
The authors studied the dissemination of information on the Patient Safety and Quality Improvement Act (PSQIA), a federal act that affords protection to those reporting medical errors. They found medical literature to be inadequate in this regard, and as a result, medical personnel were uninformed on their legal protections. This lack of information has become a barrier to policy implementation.
Jacobson, N., Butterill, D., & Goering, P. ...
EWMA 2013 - Ep574 - SOFT SILICONE AND LINOLEIC ACID TO TREAT CHONICAL WOUND I...EWMAConference
Vania Declair Cohen - RN, MS, Phd - Clinical Pharmacologist, Dermatology Specialist São Paulo - SP - Brazil
Luiz Gustavo Balaguer Cruz – MD, Plastic Surgeon – Hospital 9 de Julho – São Paulo - SP - Brazil
EWMA 2013 - Ep566 - SEQUENTIAL TREATMENT OF CHRONIC WOUNDS WITH HYDRO-DESLOUG...EWMAConference
T. SEGOVIA GÓMEZ, M. BERMEJO MARTINEZ, R. MA BONILLA SÁNCHEZ
and I. TOUME(1),
N. PIELENSTICKER(2)
(1)University Hospital Puerta de Hierro Majadahonda Community of Madrid, Spain
(2) Urgo GmbH, Sulzbach, Germany
EWMA 2013 - Ep564 - DEVELOPING A TIME CONCEPT TREATMENT IN A POST-TRAUMATIC W...EWMAConference
L. BALTÀ DOMÍNGUEZ, M. BERENGUER PÉREZ, F-J. CORPAS ALCALÁ and C. SANTIAGO FERNÁNDEZ(1)
P. WILKEN(2)
(1) SAP Muntanya. Institut Català de la Salut, Barcelona, Spain
(2) URGO GmbH, Sulzbach, Germany
EWMA 2013 - Ep563 - A new anti-biofilm dressing: in vivo investigationEWMAConference
David Parsons1 PhD, MRSC CChem
Akhil Seth2 MD, BS
Thomas Mustoe2 MD, FACS
1.ConvaTec Research & Development, Flintshire, Wales, UK
2.Division of Plastic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
EWMA 2013 - Ep562 - MANAGEMENT OF AN ATYPICAL VASCULAR ULCER WITH TLC-NOSF DR...EWMAConference
M. NOU, A. KHAU VAN KIEN, T. BEHAR, D. LABAU, C. ZAPPULLA, S. MESTRE-GODIN
J.P. LAROCHE and I. QUÉRÉ (1), M. MARTIN (2)
(1) Vascular Medicine, Hôpital Saint Eloi, CHU de Montpellier, Montpellier, France
(2) Laboratoires URGO, Chenôve, France
EWMA 2013 - Ep558 - USE OF A NEW HYDRO-DESLOUGHING ABSORBENT DRESSING* IN A N...EWMAConference
L. DAVIS(1), C. BOUVIER(2)
(1) Tissue Viability Nurse, Locking Castle Medical Centre, Highlands Lane, Weston-Super-Mare, UK
(2) Laboratoires Urgo, Chenôve, France
Josef Haik MD MPH, Eyal Winkler MD, Nimrod Farber MD, Moti Harats MD, Oren Weissman MD
Department of Plastic and Reconstructive Surgery and The Burn Unit, Sheba Medical Center
ISRAEL
EWMA 2013 - Ep552 - THE USE OF URINARY BLADDER MATRIX (ACELL) IN THE TREATMEN...EWMAConference
Alexis Lanteri Parcells, M.D
Ian C. Hoppe, M.D.
Brenon Abernathie, M.D.
Ramazi O. Datiashvili, M.D. Ph.D
University of Medicine and Dentistry of New Jersey
Division of Plastic Surgery
Department of Surgery
Newark, NJ USA
EWMA 2013 - Ep547 - European wound-registry (EWR) -characteristics and method...EWMAConference
Heyer K1, Blome C1 Storck M2, Schmidt M2, Herberger K1, Imkamp U3, Wild T4, Debus S5, Augustin M1
1) Institute for Health Services Research in Dermatology and Nursing, University Medical Center, Hamburg-Eppendorf
2) Clinic for Vascular and Thoracic surgery, Karlsruhe,
3) Mamedicon GmbH, Magdeburg,
4) German Wound Academy,
5) Clinic for Vascular Surgery, University Medical Center, Hamburg-Eppendorf
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
EWMA 2013 - Ep500 - The Role of the Pharmacist as a Member of a Multidisciplinary Team in Wound Management - A Systematic Review
1. The Role of the Pharmacist as a Member of a Multidisciplinary
Team in Wound Management - A Systematic Review
1 Aisling English (Final Year Pharmacy Undergraduate Student) 2 Dr Zena Moore (Supervisor)
1 School of Pharmacy, 2Faculty of Nursing & Midwifery , 1,2Royal College of Surgeons in Ireland, Dublin 2, Ireland
2. Background
Wounds are a significant global problem
impacting negatively on health and social gain
Due to the complex nature of wounds, a
multidisciplinary approach is required to
ensure the delivery of cost effective, efficient
care pathways1
Pharmacists, as members of an integrated
wound team, have the potential to contribute to
enhancing patient outcomes and delivery of
care
3. Aims and Outcomes
The aim of this systematic review was to
investigate the role of the pharmacist as a member
of a multidisciplinary team in wound
management
Primary Outcomes
Reduction in wound severity
Improved healing rates
Reduction in wound infection
Reduction in incidence
amputations
Secondary Outcomes
Reduction in costs
Reduction in pain
Reduction in nursing time
Improved service delivery
4. Eligible Studies and Search
Strategy
All studies which included a multidisciplinary approach
to wound management with a particular emphasis on
the role of the pharmacist were eligible for inclusion
The following databases were searched from 1993-2012
Pubmed
The Cochrane Library
Ovid EMBASE
EBSCO CINAHL
Web of Knowledge
Science Direct
6. Data Extraction and
Analysis
Data were extracted onto pre-designed
data extraction tables. Quality appraisal
was per the CONSORT statement, as
appropriate
Owing to the methodological diversity of
the studies located, no meta analysis or
meta synthesis was possible. Therefore a
narrative summary of the studies was
provided
7. Findings
Three major themes related to some, but not all of
the primary and secondary outcomes, were
identified
These themes included reference to:
Reduction in wound severity
Improved healing rates
Reduction in wound infection
Reduction in costs
Reduction in pain
Improved service delivery
8. Discussion
The three major themes were identified relating
specifically to the pharmacist’s role in wound
management and included:
Improving patient safety
Cost avoidance
Enhanced clinical outcomes
There was a lack of robust evidence to support or
refute the role of the pharmacist in wound
management
9. Discussion
The pharmacist is an
integral member of the
multidisciplinary
group and has a key
role in wound care
However, their role in
wound management as
a member of a
multidisciplinary team
has not been well
researched
10. Conclusions and Implications
for Research
This review identified three key areas where the
pharmacist had an important impact: cost
avoidance, enhancing clinical outcomes and
improving patient safety
However, little evidence is available that has
specifically explored their role
Further research in this area is warranted owing
to the lack of attention to the pharmacist’s role
in wound care
11. References
1. Bokhour, B.G. (2006) Communication in interdisciplinary team meetings: what are we
talking about? Journal of Inter-Professional Care. 20: 349-363
2. Vu, T., Harris, A., Duncan, G., Sussman, G. (2007) Cost effectiveness of multidisciplinary
wound care in nursing homes: a pseudo-randomized pragmatic cluster trial. Family
Practice.24: 372-379
3. Patel, N.P., Brandt, C., Yowler C.J. (2006) A prospective study of the impact of a critical care
pharmacist assigned as a member of the multidisciplinary burn care team. J Burn Care Res.
27: 310-313
4. Baker, T.L., Boyce, J., Gairy, P., Mighty, G. (2011) Interprofessional management of a
complex continuing care patient admitted with 18 pressure ulcers: a case report. Ostomy
Wound Management. 57(2): 38-47
5. Bhowmik, D., Chiranjib, B., Yadav, J., Chandira, M.R. (2009) Role of community pharmacist
in management and prevention diabetic foot ulcers and infection. Journal of Chemical and
Pharmaceutical Research. 1(1): 38-53 6. Malek, J. (2008) Diabetic foot – what a pharmacist
can do. Continuing Professional Development. 30: 656-658
6. The author is deeply grateful for the assistance and contributions of Ms. Grainne McCabe,
Librarian, Royal College of Surgeons in Ireland (RCSI)
12. The Role of the Pharmacist as a Member of a Multidisciplinary
Team in Wound Management - A Systematic Review
1 Aisling English (Final Year Pharmacy Undergraduate Student) 2 Dr Zena Moore (Supervisor)
1 School of Pharmacy, 2Faculty of Nursing & Midwifery , 1,2Royal College of Surgeons in Ireland, Dublin 2, Ireland