Vania Declair Cohen - RN, MS, Phd - Clinical Pharmacologist, Dermatology Specialist São Paulo - SP - Brazil Luiz Gustavo Balaguer Cruz – MD, Plastic Surgeon – Hospital 9 de Julho – São Paulo - SP - Brazil

1. Vania Declair Cohen - RN, MS, Phd - Clinical Pharmacologist,
Dermatology Specialist São Paulo - SP - Brazil
Luiz Gustavo Balaguer Cruz – MD, Plastic Surgeon – Hospital 9 de
Julho – São Paulo - SP - Brazil
SOFT SILICONE AND LINOLEIC ACID
TO TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S
SYNDROME

2. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Introduction: SJOGREN´S SYNDROME is an autoimmune
disorder that affects primarily secretory glands. The most
common manifestation is keratoconjunctivitis, xerostomia,
arthritis, vasculities, peripheral neuropathy and annular erytema.
This disease can be rather difficult to diagnose and may exist as a
primary disorder or in association with ather autoimmune disease
like rheumatoid arthritis, systemic lupus erytematosus or
scleroderma

3. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Aim: The aim of this case study is to report the
successful treatment of chronic ulcers associated with
vasculitis in the lower limbs of one patient with
SJOGREN´S SYNDROME

4. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Methods: W.B. male, 68 y, HIV +, autoantibody present – anti SS-A
(Ro) and increased expression of the genes bcl-2 (anti-apoptotic
protein). The cutaneous lesions has been found due to lymphocytic
vasculitis demonstrated by mononuclear cell infiltration with
disruption of the tissue. The patient had multiple infected chronic
ulcers in bilateral lower limbs for over 10 years, which had already
been subjected to various types of treatment without success.

5. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Methods: After the first assessment wounds was treated
with silver soft silicone foam dressing for two weeks to
relief sustained pain, promote healing environment and
reduce critical colonization. Thereafter, we stated the
treatment with soft silicone associated with linoleic acid
with retinol palmitate and d-alpha-tocoferol.

6. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Results: The wound showed improvements. The
dressing showed healing environment and pain relieve.
Linoleic acid improved the granulation and
epitalization tissue. These wounds showed completely
healing after tem weeks.

7. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHRONICAL WOUND IN A PATIENT
WITH SJOGREN’S SYNDROME

8. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHRONICAL WOUND IN A PATIENT
WITH SJOGREN’S SYNDROME

9. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Conclusion: The skin lesions associated with autoimune
disease should be carefully evalueted. Dressins with silver,
silicone and unsaturated fatty acids can be na excellent
treatment option, however, studies must be conducted in
order to highlight scientific evidence.

10. SOFT SILICONE AND LINOLEIC ACID TO
TREAT CHONICAL WOUND
IN A PATIENT WITH SJOGREN`S SYNDROME
• Outcomes:
Patient´s wife: “_ Thank you for recognizing how
important it was for my husband to be healing
when everyone said that would never be healed”