1) Enzymes: Definition, Isozymes, Oligomeric enzymes, Multi-enzyme Complexes; Components of Enzymes 2) Classification & Nomenclature of Enzymes 3) Theories of action of enzymes: Collision Theory, Transition State Theory

5. 𝑃𝑜𝑙𝑦𝑝𝑒𝑝𝑡𝑖𝑑𝑒 𝑐ℎ𝑎𝑖𝑛
𝐶𝑎𝑡𝑎𝑙𝑦𝑡𝑖𝑐 𝑑𝑜𝑚𝑎𝑖𝑛𝑠

6. 𝑇𝑦𝑝𝑒𝑠 𝑜𝑓 𝐶𝑜𝑓𝑎𝑐𝑡𝑜𝑟𝑠
𝑰𝒏𝒐𝒓𝒈𝒂𝒏𝒊𝒄 𝑖𝑜𝑛𝑠
(𝑀𝑒𝑡𝑎𝑙 𝑖𝑜𝑛𝑠)
𝐸𝑔. 𝐹𝑒2+
, 𝐶𝑢2+
𝐶𝑜𝑚𝑝𝑙𝑒𝑥 𝑶𝒓𝒈𝒂𝒏𝒊𝒄
𝑚𝑜𝑙𝑒𝑐𝑢𝑙𝑒𝑠 𝑐𝑎𝑙𝑙𝑒𝑑
"𝐶𝑜𝑒𝑛𝑧𝑦𝑚𝑒𝑠"

8. 𝑬𝒙𝒂𝒎𝒑𝒍𝒆𝒔:
𝑖 𝑁𝑖𝑐𝑜𝑡𝑖𝑛𝑎𝑚𝑖𝑑𝑒 𝑎𝑑𝑒𝑛𝑖𝑛𝑒 𝑑𝑖𝑛𝑢𝑐𝑙𝑒𝑜𝑡𝑖𝑑𝑒 𝑵𝑨𝑫 :
𝑎𝑐𝑐𝑒𝑝𝑡𝑠 ℎ𝑦𝑑𝑟𝑜𝑔𝑒𝑛 𝐻+ 𝑎𝑛𝑑
𝑔𝑖𝑣𝑒𝑠 𝑖𝑡 𝑢𝑝 𝑖𝑛 𝑎𝑛𝑜𝑡ℎ𝑒𝑟 𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛
𝑖𝑖 𝐴𝑑𝑒𝑛𝑜𝑠𝑖𝑛𝑒 𝑡𝑟𝑖𝑝ℎ𝑜𝑠𝑝ℎ𝑎𝑡𝑒 𝑨𝑻𝑷 :
𝑔𝑖𝑣𝑒𝑠 𝑢𝑝 𝑝ℎ𝑜𝑠𝑝ℎ𝑎𝑡𝑒 𝑖𝑛 𝑜𝑛𝑒 𝑟𝑒𝑎𝑐𝑛
𝑤ℎ𝑖𝑙𝑒 𝑡𝑟𝑎𝑛𝑠𝑓𝑒𝑟𝑟𝑖𝑛𝑔
𝑐ℎ𝑒𝑚𝑖𝑐𝑎𝑙 𝑒𝑛𝑒𝑟𝑔𝑦 𝑎𝑛𝑑 𝑟𝑒𝑎𝑐𝑞𝑢𝑖𝑟𝑒𝑠 𝑖𝑡 𝑖𝑛 𝑎𝑛𝑜𝑡ℎ𝑒𝑟 𝑟𝑒𝑎𝑐𝑛
𝐴𝑇𝑃 ⇌ 𝐴𝐷𝑃 + 𝑖𝑃 + ∆
𝑖𝑖𝑖 𝑚𝑜𝑠𝑡 𝐵 − 𝑉𝑖𝑡𝑎𝑚𝑖𝑛𝑠

11. 𝑆𝑢𝑏𝑠𝑡𝑟𝑎𝑡𝑒𝑠
𝐴𝑐𝑡𝑖𝑣𝑒 𝑠𝑖𝑡𝑒
𝐸𝑛𝑧𝑦𝑚𝑒
𝑆𝑢𝑏𝑠𝑡𝑟𝑎𝑡𝑒
𝐶𝑜𝑚𝑝𝑙𝑒𝑥
𝑃𝑟𝑜𝑑𝑢𝑐𝑡
𝐴𝑐𝑡𝑖𝑣𝑒 𝑠𝑖𝑡𝑒
𝑟𝑒𝑎𝑑𝑦 𝑓𝑜𝑟
𝑎𝑛𝑜𝑡ℎ𝑒𝑟
𝑠𝑢𝑏𝑠𝑡𝑟𝑎𝑡𝑒
𝑚𝑜𝑙𝑒𝑐𝑢𝑙𝑒

15. 𝑅𝑒𝑑𝑢𝑐𝑡𝑖𝑜𝑛
(𝑜𝑓 𝐴)
𝑂𝑥𝑖𝑑𝑎𝑡𝑖𝑜𝑛
𝐸𝑥. 𝐷𝑒ℎ𝑦𝑑𝑟𝑜𝑔𝑒𝑛𝑎𝑠𝑒, 𝑜𝑥𝑖𝑑𝑎𝑠𝑒

16. 𝑇𝑟𝑎𝑛𝑠𝑓𝑒𝑟𝑎𝑠𝑒
𝐸𝑥. 𝑇𝑟𝑎𝑛𝑠𝑎𝑚𝑖𝑛𝑎𝑠𝑒, 𝑘𝑖𝑛𝑎𝑠𝑒

17. 𝐸𝑥. 𝐿𝑖𝑝𝑎𝑠𝑒, 𝑎𝑚𝑦𝑙𝑎𝑠𝑒, 𝑝𝑒𝑝𝑡𝑖𝑑𝑎𝑠𝑒

18. 𝐸𝑥. 𝐷𝑒𝑐𝑎𝑟𝑏𝑜𝑥𝑦𝑙𝑎𝑠𝑒
𝐿𝑦𝑎𝑠𝑒𝑠

19. 𝐸𝑥. 𝐼𝑠𝑜𝑚𝑒𝑟𝑎𝑠𝑒, 𝑚𝑢𝑡𝑎𝑠𝑒
𝐼𝑠𝑜𝑚𝑒𝑟𝑎𝑠𝑒𝑠

20. 𝐸𝑥. 𝑆𝑦𝑛𝑡ℎ𝑎𝑡𝑎𝑠𝑒

23. 𝐿𝑜𝑤 𝐶𝑜𝑛𝑐. = ⇓ 𝑐𝑜𝑙𝑙𝑖𝑠𝑖𝑜𝑛𝑠 𝐻𝑖𝑔ℎ 𝐶𝑜𝑛𝑐. =⇑ 𝑐𝑜𝑙𝑙𝑖𝑠𝑖𝑜𝑛𝑠

25. ⇒ Activated Complex Theory
⇒ Absolute Rate Theory
⇒ Theory of Absolute
Reaction Rates
𝑎. 𝑘. 𝑎.

26. 𝑰𝒇 𝒓𝒂𝒕𝒆 𝒄𝒐𝒏𝒔𝒕. 𝒇𝒐𝒓 𝒕𝒉𝒆
𝒓𝒆𝒂𝒄𝒏 𝒊𝒔 𝒌𝒏𝒐𝒘𝒏, 𝒕𝒉𝒆𝒏
𝑻𝑺𝑻 𝒄𝒂𝒏 𝒃𝒆 𝒖𝒔𝒆𝒅 𝒕𝒐
𝒄𝒂𝒍𝒄𝒖𝒍𝒂𝒕𝒆:

29. 𝑆𝑢𝑐𝑐𝑒𝑠𝑠𝑓𝑢𝑙
𝐶𝑜𝑙𝑙𝑖𝑠𝑖𝑜𝑛𝑠
𝑇𝑟𝑎𝑛𝑠𝑓𝑜𝑟𝑚
𝑖𝑛𝑡𝑜
𝑶𝑹