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Endomembrane System
Endoplasmic Reticulum
Golgi Apparatus
Lysosome
Peroxisome
Vacuoles and Vesicles
Endomembrane System
Endoplasmic Reticulum
Function:
- manufactures membranes & performs
many bio-synthesis functions
Structure:
- membrane connected to nuclear
envelope & extends throughout cell
- accounts for 50% membranes in
eukaryotic cell
-rough ER = bound ribosomes
-smooth ER = no ribosomes
Endomembrane System
Two types of Endoplasmic reticulum
Rough Endoplasmic Reticulum
Smooth Endoplasmic Reticulum
Endomembrane System
Rough Endoplasmic Reticulum
Function:
-Produce proteins for export out of
cell
-protein secreting cells
-packaged into transport
vesicles for export
Endomembrane System
Rough ER
ER
Endomembrane System
Smooth Endoplasmic Reticulum
Function:
-Factory processing operations
-many metabolic processes
-synthesis & hydrolysis
-enzymes of smooth ER…
-synthesize lipids, oils,
phospholipids, steroids & sex
hormones
-hydrolysis (breakdown) of glycogen
(in liver) into glucose
-detoxify drugs & poisons (in liver)
-ex. alcohol & barbiturates
Endomembrane System
Smooth ER
ER
Endomembrane System
Golgi Apparatus
Function:
-finishes, sorts, & ships cell
products
-“shipping & receiving
department”
-center of manufacturing, warehousing,
sorting & shipping
-extensive in cells specialized for
secretion
Endomembrane System
Endomembrane System
Golgi Apparatus
● The Golgi apparatus alongside the ER by
modifying products of the ER
o –Products travel in transport vesicles
from the ER to the Golgi apparatus
o –One side of the Golgi apparatus functions
as a receiving dock for the product and
the other as a shipping dock
 –Products are modified as they go from one
side of the Golgi apparatus to the other.
 –After going through the Golgi, the
proteins (or other stuff) is shipped out in
a new set of vesicles.
Endomembrane System
“Receiving” side of
Golgi apparatus
Transport vesicle
from ER
New vesicle
forming
“Shipping” side
of Golgi apparatus
Transport
vesicle from
the Golgi
Endomembrane System
Lysosomes
Structure:
-membrane-bounded sac of
hydrolytic enzymes that digests
macromolecules
-enzymes & membrane of lysosomes
are synthesized by rough ER &
transferred to the Golgi
only in animal cells
Endomembrane System
Lysosomes
-Function:
-a little “stomach” for the cell
-lyso = breaking things apart
–some = body
-also the “clean up crew” of the cell
Endomembrane System
-One of the several functions of
lysosomes is to remove or recycle
damaged parts of a cell
–The damaged organelle is first enclosed
in a membrane vesicle
–Then a lysosome fuses with the vesicle,
dismantling its contents and breaking down
the damaged organelle
Lysosomes
Endomembrane System
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Endomembrane System
Peroxisome
-Other digestive enzyme sacs
-in both animals & plants
-breakdown fatty acids to sugars
-easier to transport & use as energy
source
-detoxify cell
-detoxifies alcohol & other poisons
-produce peroxide (H2O2)
-must breakdown H2O2 → H2O
Endomembrane System
Vacuoles and Vesicles
Function:
-little “transfer ships”
-Food vacuoles
-phagocytosis, fuse with
lysosomes
-Contractile vacuoles
-in freshwater protists, pump
excess H2O out of cell
-Central vacuoles
-in many mature plant cells
Endomembrane System
Vacuoles and Vesicles
Vacuoles
Transport
Vesicles
Endomembrane System
Data are presented.
Abort

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Endomembrane System