Edward Jenner was an English physician born in 1749 who discovered vaccination for smallpox. He observed that dairy workers who had previously contracted cowpox did not later get smallpox. In 1796, he took material from a cowpox blister and inoculated an 8-year old boy, later exposing him to smallpox with no illness resulting. Jenner published his findings in 1798. By 1800, over 100,000 people worldwide had been vaccinated. Jenner's discovery led to the eradication of smallpox and saved millions of lives. He received honors but died in 1823 before being elected to the College of Physicians.

1. AMI Shishu Mandir
Gwalior
Presented by: Kavya Mane
Swarangi Yadav
Twinkle Chawla
Naina Jain
Class – 9th
B
Presented to: Nagma Mam

2. British
May 17
January 26

3. Childhood & Early Life
 Edward Jenner was born to a clergy named Reverand Stephen Jenner
on 17th May, 1749, at Berkeley, Gloucestershire. Amongst the nine
children born to his parents, he was the eighth.
 He pursued his primary education at places like Cirencester and the
market town of Worren-under-Edge. During his younger days, Jenner
had contracted the dreaded smallpox epidemic and had to deal with
this health problem for the rest of his life.
 Edward started interning as a medical practitioner, under the
guidance of a surgeon named Daniel Ludlow, when he was barely
fourteen years old. After working with Ludlow for a period of seven
years, he gained enough experience to begin his career as a full-
fledged physician.

4. Career
In 1770, he moved to the esteemed ‘St. George’s
hospital’, located in London, where he worked
under the apprenticeship of renowned
physician John Hunter. He even pursued his
studies in Anatomy at the same time.
His mentor John enlightened Edward about the
renowned physician William Harvey’s approach
towards medicine, which greatly helped the
young man in his career.

5. Career
After spending three years with John Hunter,
Jenner returned to Gloucestershire in 1773 to
work as a doctor. He then started a consortium of
medical practitioners called ‘Fleece Medical
Society’, also popularly known as
‘Gloucestershire Medical Society’, along with few
other contemporary physicians.
During the various gatherings of this medical
society, this physician presented papers which
gave an insight of various ailments such as
Opthalmia, Angina Pectoris, Cowpox and Cardio
Vascular diseases.

6. Career
Jenner ventured into Zoology during the 1780’s,
by penning his observations about the bird
Cuckoo. The physician had inferred that Cuckoo
babies had a depression on their backs, which
helped in keeping the other eggs in the nest
secure and preventing any form of damage.
His findings about Cuckoo birds were well-
lauded and appeared in the premier scientific
association’s journal, ‘Philosophical Transactions
of the Royal Society’, in 1788.

7. Career
Jenner pursued his higher studies in
medicine by enrolling himself at the
renowned ‘University of St Andrews’,
located in Scotland. He graduated from this
repute institution in the year 1792.
Jenner’s main contribution to the field of
medicine was discovering a vaccination for
Smallpox, based on his observation that
the pus of Cowpox blisters has the ability
to cure Smallpox.

8. Career
Edward was appointed the president of the
‘Jennerian Society’ in the year 1803, at London.
The objective of this society was to raise
awareness about the vaccination that had the
ability to eradicate Smallpox. However, this
society had to be shut after a period of six years.
In 1805, this physician became an integral part of
another consortium, known as the ‘Medical and
Chirurgical Society’, which was later re-
christened as the ‘Royal Society of Medicine’.

9. The Problem of Smallpox
At this time, smallpox was a serious problem in
Britain and elsewhere. Many approaches to treatment
had been attempted, and both the Chinese and the
Turks had independently discovered that a person
who had suffered only a mild case of smallpox would
be immune from ever catching the disease again.
Inoculation, as the practice of deliberately injecting
smallpox for this reason was called, was the primary
means of protection against smallpox in the 18th
century, but it was extremely dangerous as it could
not be predicted in advance how severe the disease
would be in any particular person; many died, or were
terribly disfigured from the after-effects of the large
scabs that formed.

10. Smallpox and Cowpox
While working in his role as a country physician, Jenner
realized that dairy workers who had had cowpox were
apparently immune to smallpox. Since cowpox was highly
reminiscent of a mild case of smallpox in its symptoms,
Jenner wondered whether the two might be connected.
He formulated a theory that the deliberate provocation of
cowpox might be a safer method of protecting against
smallpox than simple inoculation. However, the medical
establishment of the day was unreceptive and suspicious
of the whole idea. Jenner pushed to bring vaccination
with cowpox from a local superstition to an accepted
medical practice.

11. Experimenting with Cowpox
After spending more than 20 years studying cowpox and
smallpox cases, Jenner was ready to proceed with a step
that, if it failed, might see him branded a criminal. In
1796, he took a sample from a dairy maid who had cowpox
and injected into a local boy, James Phipps.
Six weeks later, he took the hugely risky step of injecting
the same boy with smallpox. Had he become ill with the
more serious disease, Jenner would have been at best
vilified and at worst, arrested for murder. However, the
boy remained healthy, and Jenner’s new method – which
he called vaccination – had been justified.

12. Publishing His Findings
Jenner quickly published a paper about his findings,
which became hugely sought after all over Europe. Within
two years, 12,000 people in England had been vaccinated
and smallpox deaths had fallen by two-thirds. Demand
for vaccination grew, and by 1800 more than 100,000
people all over the world had received the new miracle
injection. Jenner realized that it was possible to dry
lymph fluid from a smallpox pustule and keep it in dried
form for several months, allowing for easier
transportation. This in turn allowed patients to be treated
much more easily, even in remote and outlying districts.

13. Major Works
Jenner turned into a world renowned doctor
through his invention of the vaccine to eradicate
smallpox. He apparently scraped the pus formed
on the bodies of people infected with Cowpox
and injected it in the body of his gardener’s son.
Although the boy suffered from fever initially,
he became immune to Smallpox.
This renowned doctor was appointed as the
personal physician of the ruler, King George IV,
in 1821. Very few physicians from England had
received the honour of serving the monarch.

15. Jenner’s Rewards
In 1798, after several other successful
tests, Jenner finally published his
findings in a publication called An
Inquiry into Causes plus the Effects of
Variolae Vaccine. He called his idea
“vaccination,” from vaccinia, which is a
Latin word for cowpox. After so much
ridicule, other doctors finally found out
that the vaccination really worked and
by 1800, a large number of them were
using it.

16. Jenner’s Rewards
His continued works on
vaccination prevented him
from continuing the ordinary
medical practice. He was even
granted $10,000 for his great
work. In 1806, he was given
another $20,000 to continue
his work.

17. Jenner’s Honors and Legacy
Jenner became one of the most popular
and respected men in the western world
for his work. In 1804, Napoleon
Bonaparte agreed to a request Jenner
made for the release of a number of
Englishmen, despite the fact that the
two nations were at war. In the United
States, Thomas Jefferson vaccinated his
family at Monticello with material he
had been sent by Jenner.

18. Jenner’s Honors and Legacy
Despite his fame, however, the medical
establishment in Jenner’s home country denied him
entry into London’s College of Physicians unless he
first took an exam on Galenic and Hippocratic theory.
Jenner refused, stating that his work was his
qualification, and he was never elected a college
member.
As well as his work in medicine, Jenner was
interested in the natural world. He had been a Fellow
of the Royal Society since 1788, on account of a
thorough and detailed study of the life of the cuckoo
in the nest, and now he spent a considerable amount
of time collecting fossils, as well as tending to his
plants.

19. Jenner’s Honors and Legacy
Jenner died of tuberculosis on January
26, 1823. By the time of his death,
vaccination was firmly established as
the best method of preventing
smallpox, and it was later extended to
many other viral diseases. Thanks to his
pioneering work, Jenner is sometimes
considered to have saved more people
by his scientific endeavors than anyone
else in history.