This editorial discusses positive (expansive) remodeling as a potential surrogate marker for plaque inflammation and vulnerability. The editorial summarizes several studies that found associations between expansive remodeling and histological markers of vulnerability in unruptured plaques as well as clinical associations with unstable syndromes. One such study found that plaques with expansive remodeling had larger lipid cores and more macrophages compared to those with constrictive remodeling in patients who died from coronary artery disease. While expansive remodeling may prevent luminal narrowing long-term, it may destabilize plaques and increase risk of rupture in the short-term. Further research is needed to understand the predictive value of arterial remodeling patterns and identify ways to induce beneficial expansive remodeling without increasing