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ECHOCARDIOGRAPHIC 
ASSESMENT OF AORTIC VALVE 
DISEASES
Aortic stenosis: Classification based on 
location 
Valvular- 
most common type. 
Subvalvular. 
Supravalvular.
Valvular Aortic Stenosis: Etiology
Aortic Sclerosis
Bicuspid Aortic Valve
Bicuspid Aortic Valve
Congenital Anomalies Of AV valve
Calcific Aortic Stenosis of trileaflet valve
Rheumatic aortic stenosis
Subvalvular aortic stenosis
Supravalvular aortic stenosis
Echocardiographic assessment 
of severity
Doppler assessment of AS 
(EAE/ASE Recommendations for Clinical Practice 2009).
Classification of AS severity 
(based on 2014 AHA/ACC Valvular heart disease guideline)
Peak transvalvular velocity measurement
Peak transvalvular velocity
Peak transvalvular velocity
Mean transvalvular gradient
Mean transvalvular gradient
Sources of error for pressure gradient 
calculations
Sources of error for pressure gradient 
calculations
Aortic valve area Continuity equation
Aortic valve area Continuity equation
Advantage of the Continuity Equation over Peak 
velocity Pressure gradient
Pitfalls of the Continuity Equation
Pitfalls of the Continuity Equation
Low-flow low-gradient AS
Low Dose Dobutamine Stress Echo- 
Protocol
Low Dose Dobutamine Stress Echo
Effects of concurrent conditions on 
assessment of severity
Effect of LVH
Effect of LVH
Effect of Hypertension
Effect of Aortic Regurgitation
Effect of Mitral valve disease
M Mode- Aortic Stenosis 
DeMaria A N et al. Circulation.Suppl II. 58:232,1978
ECHOCARDIOGRAPHIC ASSESSMENT 
OF AORTIC REGURGITATION
MILD MODERATE SEVERE 
Jet width/LVOT 
diameter 
<25% >/=65% 
Vena contracta <3mm >/=6mm 
Jet area/LVOT 
area 
<5% >60% 
PHT >500 ms </= 250ms 
Holodiastolic 
flow reversal 
present
MILD MODERATE SEVERE 
Reg vol < 30 ml >/= 60 ml 
Reg fraction < 30 % >/= 50% 
ERO < 0.1 cm2 >/= 0.3 cm2 
Mitral inflow 
restriction 
Present
AR – VC, Jet width / Lvot width
• Regurgitant jet height measured as maximal diameter of 
regurgitant jet just below AV,PLAX view 
• LVOT diameter in end diastole
Regurgitant jet width/LVOT diameter ratio 
greater than or equal to 60 percent
Vena contracta greater than 6 mm
AR – Jet area / Lvot area
• Regurgitant jet area measured from PSAX view at level of 
LVOT 
• LVOA measured at end diastole at same site 
• Ratio calculated
AR – Pressure Half Time
• Regurgitant doppler signal is a function of pressure 
gradient between aorta and LV 
• Mild AR –small increase in LVEDP-gradual decline and 
flat deceleration slope 
• Severe AR –LVEDP rises rapidly-rapid decline
• Suprasternal window-descending aortic flow profile 
• Short period of low velocity flow reversal-normal 
• Pan diastolic flow reversal with end diastolic 
velocity>20cm/s
Calculation of R.Volume and R.fraction 
• SV=CSAxVTI 
• R.Volume=SV[lvot]-SV[mv] 
• RF=R.Volume/SV[lvot] 
• ERO=R.Volume/VTI[ARjet] 
• R.V>60ml,RF>50%,ERO>0.3cm² indicate severe AR
Restrictive mitral flow pattern
Extent of jet
Signal intensity
Classification of AS severity 
(based on 2014 AHA/ACC Valvular heart disease guideline)
SEVERITY 
• 1. Regurgitant jet width/LVOT diameter ratio greater than or equal to 60 
percent 
• 2. Vena contracta greater than 6 mm 
• 3. Regurgitant jet area/LVOT area ratio greater than or equal to 60 
percent 
• 4. Aortic regurgitation pressure half-time less than or equal to 250 ms 
• 5. Holodiastolic flow reversal in the descending thoracic or abdominal 
aorta 
• 6. Regurgitant volume greater than or equal to 60 mL 
• 7. Regurgitant fraction greater than or equal to 50 percent 
• 8. Effective regurgitant orifice greater than or equal to 0.30cm2 
• 9. Restrictive mitral flow pattern (usually in acute setting)
THANK YOU..

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Echo assesment of Aortic Stenosis and Regurgitation

Editor's Notes

  1. even in the absence of valve obstruction, is associated with a 50% increased risk of CV death and MI.
  2. In adults, stenosis in BAV is d/t calcific changes, which often obscures the number of cusps, making determination of bicuspid vs. tricuspid valve difficult.
  3. Stellate- resembling a star.
  4. TTE for reevaluation of asymptomatic patients with AS with normal LV systolic function who have no change in signs or symptoms is performed at intervals of 6 months to 1 year when aortic velocity is ³4.0 m per second (stage C), 1 to 2 years when aortic velocity is between 3.0 m per second and 3.9 m per second (stage B), and 3 to 5 years when aortic velocity is 2.0 m per second to 2.9 m/s (stage B)
  5. the simplified Bernoulli equation assumes that the proximal velocity can be ignored, a reasonable assumption when prox velocity is less than 1 m/s, because squaring a number less than 1 makes it even smaller. When the proximal velocity is over 1.5 m/s or the aortic velocity is less than 3.0 m/s, the proximal velocity should be included in the Bernoulli equation so that DP ¼ 4 v2 max v2 proximal when calculating maximum gradients. It is more problematic to include proximal velocity in mean gradient calculations as each point on the ejection curve for the proximal and jet velocities would need to be matched and this approach is not used clinically. In this situation maximum vel and gradient should be used to grade stenosis severity.
  6. Any underestimation of aortic velocity results in an even greater underestimation in gradients. due to the squared relationship between velocity and pressure difference
  7. Severe AS causing LV systolic dysfunction. An inverse correlation between wall stress and ejection fraction has been described in patients with AS. This suggests that the depressed ejection fraction and velocity of fiber shortening that occur in some patients are a consequence of inadequate wall thickening, resulting in afterload mismatch. In others, the lower ejection fraction is secondary to a true depression of contractility. In this situation, aortic valve replacement will relieve afterload and may allow the LV ejection fraction to increase towards normal. Moderate AS with another cause of LV dysfunction (e.g. myocardial infarct or a primary cardiomyopathy). The effective orifice area is then low because the LV does not generate sufficient energy to overcome the inertia required to open the aortic valve to its maximum possible extent. In this situation, aortic valve replacement may not lead to a significant improvement in LV systolic function.
  8. The echocardiographic report should always include a blood pressure measurement recorded at the time of the examination to allow comparison between serial echocardiographic studies and with other clinical data.
  9. TTE for reevaluation of asymptomatic patients with AS with normal LV systolic function who have no change in signs or symptoms is performed at intervals of 6 months to 1 year when aortic velocity is ³4.0 m per second (stage C), 1 to 2 years when aortic velocity is between 3.0 m per second and 3.9 m per second (stage B), and 3 to 5 years when aortic velocity is 2.0 m per second to 2.9 m/s (stage B)