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PHARMACOTHERAPY
Learning outcome :
• Be able to choose drugs for the patients rationally
• ( based on efficacy, safety, acceptability, cost
effectiveness )
Learning objective :
• Be able to select drug dosage forms according to
patient
• Be able to decide drug dose regimens to the patient
• To consider about drug interaction and adverse drug
reactions
• Demonstrate the ability to do the rational drug
prescribing
DRUGS DOSE
• MINIMAL DOSE: minimal amount of drug which still give
therapeutic effect
• THERAPEUTIC DOSE / USUAL DOSE : amount of drug
which can give therapeutic effect
• MAXIMAL DOSE : a maximal amount of drug which still
safe be given without acute toxicity symptom
• TOXIC DOSE : amount of drug which give toxicity
symptom
• LETHAL DOSE : amount of drug that can kill some of
animal laboratory. LD50 mean 50 % animal lab.was kill
• FATAL DOSE : amount of drug that can kill a person
THE PRESCRIPTION
• Request from doctor to pharmacist prepare the drug which
finally passed to patient.
• An order written by a physician, dentist, veterinarian,
directing to pharmacist to compound and dispense
medication for a patient
The part of prescription
1. Inscriptio  dr. identify, town, date, R/
2. Ordinatio/Praescriptio  name, form,
quantity
3. Signatura  how to use, patient identify
4. Subscriptio  dr. sign
EXAMPLE OF PRESCRIPTION
Dr.Iwan Dps May 07
Lissence
Address
R/ Amoxicillin 250 mg caps no.XV
S.3 d.d.caps I
==== sign
Pro : Amin ( dewasa )
Add: jl. Gorris 1 Dps
Pulvis : R/ Herocyn powder fl. no. I
S.u.e.
=====sign
Pulveres : R/ Amoxicillin mg 125
Paracetamol mg 200
M. f. pulv. dtd. no. XV
S. 3 d.d.pulv. I
====== sign
Tablet : R/ Antalgin 500 mg tab. No. XV
S. 3 d.d. tab. I
======
Capsul : R/ Tetracyclin 250 mg Caps. No.XX
S. 4 d.d.Caps I
======
Suppositoria: R/ Anusol Suppos. No.V
S.1d.d.I intra anus
=====
Syrup : R/ Panadol Syr. fl. No. I
S. 3 d.d. Cth. I
=====
Drop / Guttae : R/ Colme eye drop fl.No. I
S. 4 d.d.gtt. I
=====
Solution : R/ Betadine sol.fl. No. I
S.u. e.
=======
Ointment : R/ Terracortryl oint tube no. I
S. u. e.
=====
Cream : R / Counterpain cream tube no I
S.u.e.
=====
Parenteral : R/ Adrenalin inj. ampul no. X
S i.m.m.
=====
R/ Xylomidon vial no. II
S. i. m.m.
======
R/ Dextrose infus fl.no. I
S.i.m.m.
=====
S.u.e.=Signa usus externus=tandailah untuk
pemakaian luar
S.3 d.d.= Signa ter de die=tandailah 3 x
sehari
d.t.d.=da tales dosis= masing-masing
dosisnya seperti diatas
fl. = flash= botol kecil
T H A N K Y O U
Contoh Form Resep (Goth,1978) :
Nama Dokter
Alamat Rumah
Alamat Praktek
SIP
Tanggal Kota ,tanggal
Superscriptio R/
Inscriptio/Pr
escriptio
Subscriptio
R.Cardinale
R.Adjuvan
Corrigen rasa,
bau, warna
Vehiculum
Perintah
pembuatan
m f l a------
Dosis
(mg,ml)
Dosis
(mg,ml)
Jumlah obat
Signatura S.Aturan pemakaian obat
Paraf/tanda tangan
Nama pasien
Alamat
Dosage form of drug
Dosage form of drug
Dosage form of drug

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Dosage form of drug

  • 1. PHARMACOTHERAPY Learning outcome : • Be able to choose drugs for the patients rationally • ( based on efficacy, safety, acceptability, cost effectiveness ) Learning objective : • Be able to select drug dosage forms according to patient • Be able to decide drug dose regimens to the patient • To consider about drug interaction and adverse drug reactions • Demonstrate the ability to do the rational drug prescribing
  • 2. DRUGS DOSE • MINIMAL DOSE: minimal amount of drug which still give therapeutic effect • THERAPEUTIC DOSE / USUAL DOSE : amount of drug which can give therapeutic effect • MAXIMAL DOSE : a maximal amount of drug which still safe be given without acute toxicity symptom • TOXIC DOSE : amount of drug which give toxicity symptom • LETHAL DOSE : amount of drug that can kill some of animal laboratory. LD50 mean 50 % animal lab.was kill • FATAL DOSE : amount of drug that can kill a person
  • 3. THE PRESCRIPTION • Request from doctor to pharmacist prepare the drug which finally passed to patient. • An order written by a physician, dentist, veterinarian, directing to pharmacist to compound and dispense medication for a patient The part of prescription 1. Inscriptio  dr. identify, town, date, R/ 2. Ordinatio/Praescriptio  name, form, quantity 3. Signatura  how to use, patient identify 4. Subscriptio  dr. sign
  • 4. EXAMPLE OF PRESCRIPTION Dr.Iwan Dps May 07 Lissence Address R/ Amoxicillin 250 mg caps no.XV S.3 d.d.caps I ==== sign Pro : Amin ( dewasa ) Add: jl. Gorris 1 Dps
  • 5. Pulvis : R/ Herocyn powder fl. no. I S.u.e. =====sign Pulveres : R/ Amoxicillin mg 125 Paracetamol mg 200 M. f. pulv. dtd. no. XV S. 3 d.d.pulv. I ====== sign
  • 6. Tablet : R/ Antalgin 500 mg tab. No. XV S. 3 d.d. tab. I ====== Capsul : R/ Tetracyclin 250 mg Caps. No.XX S. 4 d.d.Caps I ====== Suppositoria: R/ Anusol Suppos. No.V S.1d.d.I intra anus ===== Syrup : R/ Panadol Syr. fl. No. I S. 3 d.d. Cth. I ===== Drop / Guttae : R/ Colme eye drop fl.No. I S. 4 d.d.gtt. I ===== Solution : R/ Betadine sol.fl. No. I S.u. e. =======
  • 7. Ointment : R/ Terracortryl oint tube no. I S. u. e. ===== Cream : R / Counterpain cream tube no I S.u.e. ===== Parenteral : R/ Adrenalin inj. ampul no. X S i.m.m. ===== R/ Xylomidon vial no. II S. i. m.m. ====== R/ Dextrose infus fl.no. I S.i.m.m. =====
  • 8. S.u.e.=Signa usus externus=tandailah untuk pemakaian luar S.3 d.d.= Signa ter de die=tandailah 3 x sehari d.t.d.=da tales dosis= masing-masing dosisnya seperti diatas fl. = flash= botol kecil T H A N K Y O U
  • 9. Contoh Form Resep (Goth,1978) : Nama Dokter Alamat Rumah Alamat Praktek SIP Tanggal Kota ,tanggal Superscriptio R/ Inscriptio/Pr escriptio Subscriptio R.Cardinale R.Adjuvan Corrigen rasa, bau, warna Vehiculum Perintah pembuatan m f l a------ Dosis (mg,ml) Dosis (mg,ml) Jumlah obat Signatura S.Aturan pemakaian obat Paraf/tanda tangan Nama pasien Alamat