This document summarizes guidelines for managing the unanticipated difficult airway. It outlines a 4-plan approach:
Plan A is the initial intubation attempt. Plan B is secondary intubation methods if Plan A fails, such as video laryngoscopy or supraglottic airway devices. Plan C focuses on oxygenation and ventilation if intubation still cannot be achieved.
Plan D describes rescue techniques for "can't intubate, can't ventilate" situations. It recommends cannula cricothyroidotomy as first-line over surgical cricothyroidotomy, as studies show anaesthetists have lower success rates with scalpel techniques than surgeons. Proper training and familiar equipment are
Mechanical ventilation ppt including airway, ventilator, tubings and connections, nursing management, trouble shooting common problems and issues, suctioning etc.
indication foe intubation ,routes of intubation , the role of nurse in intubation ,indication of mechanical ventilation ,ventilators ,ventalotory modes and its advantages and disadvantages , complication of mechanical ventilation , nursing Management for patients on ventilator ,suction technique and weaning process
Predictors of weaning from mechanical ventilator outcomeMuhammad Asim Rana
This is a very useful presentation for respiratory therapists and ICU and Emergency physicians. Intended to teach how to assess you patient's readiness for weaning from mechanical ventilator and successful separation from machine.
This presentation describes the indications, contraindications, methods of performing spirometry. It explains the interpretation of spirometry with examples.
Mechanical ventilation ppt including airway, ventilator, tubings and connections, nursing management, trouble shooting common problems and issues, suctioning etc.
indication foe intubation ,routes of intubation , the role of nurse in intubation ,indication of mechanical ventilation ,ventilators ,ventalotory modes and its advantages and disadvantages , complication of mechanical ventilation , nursing Management for patients on ventilator ,suction technique and weaning process
Predictors of weaning from mechanical ventilator outcomeMuhammad Asim Rana
This is a very useful presentation for respiratory therapists and ICU and Emergency physicians. Intended to teach how to assess you patient's readiness for weaning from mechanical ventilator and successful separation from machine.
This presentation describes the indications, contraindications, methods of performing spirometry. It explains the interpretation of spirometry with examples.
Weaning and Discontinuing Ventilatory Supporthanaa
1) The epidemiology of weaning
2) Evidence-based weaning guidelines
3) The pathophysiology of weaning failure
4) Is there a role for different ventilator modes in weaning?
Journal Presentation on article Comparative efficacy of different combination...Shubham Jain
Journal Presentation on article Comparative efficacy of different combinations of acapella, active cycle of breathing technique, and external diaphragmatic pacing in perioperative patients with lung cancer
Dr. Akira Nishisaki (Children's Hospital of Philadelphia) talks about A Just-in-Time Training study on pediatric advanced airway skills at the CHOP PICU.
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
25. • Distance from the upper border of the
manubrium to the tip of mentum, neck
fully extended, mouth closed
• Minimal acceptable value – 12.5 cm
• Single best predictor of difficult
laryngoscopy and
intubation ( Has high sensitivity &
specificity).
STERNO-MENTALDISTANCE (SA
VV
ATEST)
26.
27.
28. X-Ray neck (lateral view)
1. Occiput - C1 spinous process
distance< 5mm.
2. Increase in posterior
mandible depth > 2.5cm.
3. Ratio of effective mandibular
length to its posterior depth
<3.6.
4. Tracheal compression
CT Scan:
1. Tumors of floor of
mouth, pharynx, larynx
2. Cervical spine
trauma, inflammation
3. Mediastinal mass
Helical CT (3D-reconstruction):
• Exact location and degree of airway
compression
Bed side Ultrasound
Trachea, Soft tissues
Radiological assessment
38. Sniffing position
• The end point of the position should be verified
by checking the horizontal alignment of the
external auditory meatus with the sternum notch
• The mode value of neck flexion angle was 35° and
that of plane of the face extension was 15° to the
horizontal
• Other factor; include the a)type and size of the
blade, b)laryngoscope lifting force, c)operator
experience,and d) most importantly, the patient’s
airway anatomy
39. How to get optimal sniffing position;
anesthesia and analgesia
40. • The components of best performance of
laryngoscopy consist of
-------- optimal sniff position,
---------good complete muscle relaxation,
---------experienced laryngoscopist,
---------firm forward traction on the laryngoscope
-----------external laryngeal manipulation.
43. “BURP” & “External
Laryngeal
Manipulation”
• Backward, Upward, Rightward
Pressure: manipulation of the
trachea
• 90% of the time the best view
will be obtained by pressing
over the thyroid cartilage
56. Difficult mask ventilation
• Inability to keep spo2 more than 90 percent
• Inability to reverse sigh of inadequate
ventilation
• Incidence 0.09 to 5.0%
57.
58.
59.
60. Two Types of Anatomical difficult
intubation
• Anticipated
• unanticipated
63. Physiological difficult airway
• The physiologically difficult airway can be
defined as one in which severe physiological
derangement place the patients at increased
risk of cardiovascular collapse and death
during tracheal intubation and transition to
positive pressure ventilation
72. Team preparation and positioning
itensive care medicine 2010
chest 2018
• Presence of two operator(at least one should
be skilled in the airway management)
• Use of check least
• Clear communication among the team
members about the airway concerns, air way
plan, back up plan role and responsibility of
the team members before proceeding for
tracheal intubation
98. No of Attempts of the intubation
&
limitation of attempt
99.
100. What guidelines are there and what can we
learn from them?
Plan A:
Initial tracheal
intubation plan
Plan B:
Secondary tracheal
intubation plan
Plan C:
Maintenance of
oxygenation, ventilation,
postponement of
surgery and awakening
Plan D:
Rescue techniques
for "can't intubate,
can't ventilate" situation
Direct laryngoscopy
failed intubation
succeed
succeed
Tracheal intubation
failed oxygenation
Revert to face mask
Oxygenate & ventilate
failed oxygenation
LMATM
increasing hypoxaemia
or
fail
Cannula
cricothyroidotomy
Surgical
cricothyroidotomy
improved
oxygenation
Awaken patient
Confirm - then
succeed fibreoptic tracheal
ILMATM or LMATM
intubation through
ILMATM or LMATM
Postpone surgery
Awaken patient
failed intubation
ASA
Italian
DAS
UK & I
Canadian
105. • Optimising success on first
attempt at Laryngoscopy
• Position, pre-oxygenation, muscle relaxant
• Video laryngoscope included
• There may be need of more than one tool
• Maximum 3 attempts
106. Patel at al 2015
• in extending apnoea time in pts with
difficult airways undergoing GA. There were
no saturations below 90%, despite an
average apnoea time of 17 minTHRIVE
beneficial
• Rate of rise of carbon dioxide levels was
between 0.35 and 0.45 kPa/min in
previous studies. With THRIVE, the rate of
carbon dioxide increase was 0.15 kPa/min
107.
108. • It’s about oxygenation
• 2nd generation SADs
• Maximum 3 attempts
Plan B
114. The Great Airway Debate
PRO- SURGICAL
• EVIDENCE
• SIMPLICITY
• STANDARDISATION
115. The Great Airway Debate
Is the Scalpel mightier than the
Cannula?
116. NAP4 Data CICO
• 2.9 million GAs/ yr
• 133 serious airway
complications 58 attempts at
cricothyroidotomyOf 58 invasive
airway attempts:33 by surgeon
(surgical) Majority successful
• 25 by anaesthetist Only 9 of these
successful
118. Mabry RL.
An analysis of battlefield cricothyrotomy in Iraq
and Afghanistan.
76 surgical crics with 85%
success by army doctors.
Journal of Special Operations Medicine.
2012;12(1):17-23.
119. • London Air Ambulance Service
• Largest single reported series on scalpel
bougie technique
• Done by anaesthetists and EM docs
120. • Doctor-paramedic team attended 28,939
patients
• Advanced airway management required by 7,265
(25%)
• 98 scalpel bougie procedures with 100%
success
124. • Properly trained
• Dedicated & familiar
equipment
• EXPERT at Ventilation using
high pressure oxygen through
a narrow bore cannula.
• NO need for a cuffed
Tube in place
Cannula techniques ONLY if