The document summarizes a study on dermatoglyphic patterns in 137 patients diagnosed with infantile autism. The study found a broad range of dermatoglyphic anomalies in patients with autism compared to healthy controls. Specifically:
1) Patients with autism had higher frequencies of arch patterns and lower frequencies of loop patterns on fingers compared to controls.
2) Patients also showed atypical palmar dermatoglyphic patterns including differences in ridge count patterns and triradius positions.
3) Both digital and palmar dermatoglyphic anomalies occurred more frequently in autism patients of both sexes and were often more pronounced on the left hand. These dermatoglyphic distortions
This study evaluated 7 children clinically diagnosed with Neurofibromatosis type 1 (NF-1) using MRI to look for characteristic brain lesions. 4 patients showed focal areas of increased signal on T2-weighted MRI in typical locations including the globus pallidus, midbrain, and cerebellar peduncles. These lesions were believed to represent non-neoplastic hamartomatous changes and lacked mass effect or enhancement. The study concluded these lesions are common in around 50% of children with NF-1 and represent benign vacuolar changes in myelin that increase in size and intensity from ages 8-10 years before fading in adolescence.
Brain Imaging Abnormalities in Autism Disordersasclepiuspdfs
Background: Autism disorders are heterogeneous complex group of chronic disorders that have become increasingly known as pervasive developmental disorders since the 1980s. They include five main disorders associated with significant early impairment in socialization, communication, and behavior. Autism disorders have recently been called autism spectrum disorder mostly by the American Psychiatric Association, and the term pervasive developmental disorders have been used with the term autism spectrum disorder interchangeably. The association of autism disorders with significant brain imaging abnormalities has been infrequently reported. The aim of this paper is to report the association of brain imaging abnormalities in four autistic children. Patients and Methods: Four autistic patients (three boys and one girl) who had brain imaging abnormalities and observed at the Children Teaching Hospital of Baghdad Medical City are described. Results: Three patients had atypical autism with mental retardation, and one boy had Heller syndrome (childhood disintegrative disorder). The girl had right anterior basal temporal small arachnoid cyst on computed tomography (CT) scan. One of the boys with atypical autism also had mild cerebral palsy attributed to birth asphyxia and his CT scan showed evidence of slight brain atrophy with mild dilatation of the ventricular system. Conclusion: Brain imaging abnormalities in patients with autism disorders include arachnoid cyst, agenesis of the corpus callosum, evidence of vasculitis (in Heller syndrome), and brain imaging abnormalities related to a coexisting condition such as cerebral palsy.
This document provides an overview of autism, including:
- A brief history noting its identification in 1943.
- Statistics indicating its increasing prevalence, now affecting 1 in 150 individuals.
- Etiology involving both genetic and environmental factors.
- Diagnostic criteria outlined in the DSM-IV involving impairments in social interaction, communication, and restricted behaviors.
- Treatment approaches including behavioral therapies like ABA and biomedical therapies targeting underlying medical conditions.
The document summarizes recent discoveries about autism. It discusses that autism is more commonly diagnosed today, affecting 1 in 88 individuals. It also mentions that autistic individuals have higher levels of growth hormones, which may explain their larger head circumference. Additionally, research suggests autistic people are less concerned with what others think of them and have greater ability to process information compared to others. The document also notes some autistic children have distinctive facial features and premature babies have a higher risk of developing autism. Finally, it proposes some autism genes may have provided advantages for hunting and gathering in the past.
Neuropsychiatric Manifestation In 8 Years Old Girl Presented With Obstructive...AR Muhamad Na'im
This document summarizes a case report of an 8-year-old girl presenting with obstructive hydrocephalus secondary to a posterior fossa tumor. She exhibited neurological symptoms like lower limb weakness and worsening headaches, as well as psychiatric symptoms including hallucinations and delusions. Imaging showed a tumor in the posterior fossa and ventriculomegaly. Posterior fossa tumors can cause hydrocephalus by disrupting cerebrospinal fluid flow. While psychiatric issues are common post-resection, they can also arise from brain changes caused by the tumor. The patient's symptoms were likely due to the mass effect of the tumor and associated hydrocephalus.
Autism Spectrum Disorders Solutions with Your Little Professoryourlittleprofessor
Your Little Professor is a resource for families search for camps and programs for Asperger. Our website has educational information to help your teen.
This document provides an overview of Down syndrome including definitions, features in newborns, common abnormalities, and age-specific healthcare guidelines. It summarizes the incidence of Down syndrome as occurring in 1 in 660 newborns. Common physical features in newborns include slanted palpebral fissures, anomalous auricles, and hypotonia. The document outlines numerous potential abnormalities and provides healthcare guidelines for individuals with Down syndrome from the neonatal period through adulthood.
This study evaluated 7 children clinically diagnosed with Neurofibromatosis type 1 (NF-1) using MRI to look for characteristic brain lesions. 4 patients showed focal areas of increased signal on T2-weighted MRI in typical locations including the globus pallidus, midbrain, and cerebellar peduncles. These lesions were believed to represent non-neoplastic hamartomatous changes and lacked mass effect or enhancement. The study concluded these lesions are common in around 50% of children with NF-1 and represent benign vacuolar changes in myelin that increase in size and intensity from ages 8-10 years before fading in adolescence.
Brain Imaging Abnormalities in Autism Disordersasclepiuspdfs
Background: Autism disorders are heterogeneous complex group of chronic disorders that have become increasingly known as pervasive developmental disorders since the 1980s. They include five main disorders associated with significant early impairment in socialization, communication, and behavior. Autism disorders have recently been called autism spectrum disorder mostly by the American Psychiatric Association, and the term pervasive developmental disorders have been used with the term autism spectrum disorder interchangeably. The association of autism disorders with significant brain imaging abnormalities has been infrequently reported. The aim of this paper is to report the association of brain imaging abnormalities in four autistic children. Patients and Methods: Four autistic patients (three boys and one girl) who had brain imaging abnormalities and observed at the Children Teaching Hospital of Baghdad Medical City are described. Results: Three patients had atypical autism with mental retardation, and one boy had Heller syndrome (childhood disintegrative disorder). The girl had right anterior basal temporal small arachnoid cyst on computed tomography (CT) scan. One of the boys with atypical autism also had mild cerebral palsy attributed to birth asphyxia and his CT scan showed evidence of slight brain atrophy with mild dilatation of the ventricular system. Conclusion: Brain imaging abnormalities in patients with autism disorders include arachnoid cyst, agenesis of the corpus callosum, evidence of vasculitis (in Heller syndrome), and brain imaging abnormalities related to a coexisting condition such as cerebral palsy.
This document provides an overview of autism, including:
- A brief history noting its identification in 1943.
- Statistics indicating its increasing prevalence, now affecting 1 in 150 individuals.
- Etiology involving both genetic and environmental factors.
- Diagnostic criteria outlined in the DSM-IV involving impairments in social interaction, communication, and restricted behaviors.
- Treatment approaches including behavioral therapies like ABA and biomedical therapies targeting underlying medical conditions.
The document summarizes recent discoveries about autism. It discusses that autism is more commonly diagnosed today, affecting 1 in 88 individuals. It also mentions that autistic individuals have higher levels of growth hormones, which may explain their larger head circumference. Additionally, research suggests autistic people are less concerned with what others think of them and have greater ability to process information compared to others. The document also notes some autistic children have distinctive facial features and premature babies have a higher risk of developing autism. Finally, it proposes some autism genes may have provided advantages for hunting and gathering in the past.
Neuropsychiatric Manifestation In 8 Years Old Girl Presented With Obstructive...AR Muhamad Na'im
This document summarizes a case report of an 8-year-old girl presenting with obstructive hydrocephalus secondary to a posterior fossa tumor. She exhibited neurological symptoms like lower limb weakness and worsening headaches, as well as psychiatric symptoms including hallucinations and delusions. Imaging showed a tumor in the posterior fossa and ventriculomegaly. Posterior fossa tumors can cause hydrocephalus by disrupting cerebrospinal fluid flow. While psychiatric issues are common post-resection, they can also arise from brain changes caused by the tumor. The patient's symptoms were likely due to the mass effect of the tumor and associated hydrocephalus.
Autism Spectrum Disorders Solutions with Your Little Professoryourlittleprofessor
Your Little Professor is a resource for families search for camps and programs for Asperger. Our website has educational information to help your teen.
This document provides an overview of Down syndrome including definitions, features in newborns, common abnormalities, and age-specific healthcare guidelines. It summarizes the incidence of Down syndrome as occurring in 1 in 660 newborns. Common physical features in newborns include slanted palpebral fissures, anomalous auricles, and hypotonia. The document outlines numerous potential abnormalities and provides healthcare guidelines for individuals with Down syndrome from the neonatal period through adulthood.
Autism is group of child developmental disabilities that can cause social, communication and behavioural challenges in Kids. Giostar provides Stem Cell Treatment for Autism call us at +91 7043008890.
This presentation contains detailed knowledge about Down's Syndrome its types, clinical presentation, diagnosis, medical and physio therapeutic management of the condition.
Down syndrome is a condition in which a person has an extra chromosome. Chromosomes are small “packages” of genes in the body. They determine how a baby’s body forms and functions as it grows during pregnancy and after birth. Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is ‘trisomy.’ Down syndrome is also referred to as Trisomy 21. This extra copy changes how the baby’s body and brain develop, which can cause both mental and physical challenges for the baby.
This document provides details on the case of an 8 month old female child named Azma who presented with recurrent cold, cough, loose motions, and rapid breathing. It summarizes her birth history, developmental milestones, family history, clinical features, genetic causes, common health issues, diagnostic criteria, management, and prognosis of Down syndrome.
The document discusses the different types of autism spectrum disorders including Asperger's syndrome, Kanner's syndrome, pervasive developmental disorder, Rett's syndrome, and childhood disintegrative disorder. It describes the characteristics of each type, such as difficulties with social and communication skills, repetitive behaviors, and sensory processing. The causes of autism are not entirely known but are believed to involve genetic and environmental factors. While there is no cure for autism, early intervention and treatment tailored to the individual can help children develop their skills and manage symptoms.
Down Syndrome is the most common chromosomal abnormality affecting children today. It occurs in approximately 1 in 800 to 1,000 births and is caused by the presence of an extra copy of chromosome 21. Individuals with Down Syndrome often have intellectual disabilities and are at increased risk for certain medical conditions such as congenital heart disease, gastrointestinal abnormalities, hearing loss, thyroid disorders, and periodontal disease. Proper screening, monitoring, and management of associated health issues can help improve quality of life for those with Down Syndrome.
This document summarizes the clinical findings and neuropsychological assessments of three adolescent patients with Pontine Tegmental Cap Dysplasia (PTCD). All three patients presented with multiple cranial neuropathies including bilateral deafness, as well as feeding difficulties and hypotonia as infants. While their feeding difficulties resolved over time, they exhibited mild to moderate cognitive impairments, language deficits, and two showed mild behavioral issues. Brain imaging confirmed the abnormal bundle of fibres in the pons characteristic of PTCD. The outcomes suggest PTCD may have a more favorable long-term prognosis with borderline or normal cognition, and cochlear implants improved abilities for two patients.
Down syndrome is a genetic condition caused by trisomy of chromosome 21. It occurs in about 1 in 700 live births. Clinical features include intellectual disability, characteristic facial features such as a flat face, upward slanted eyes, and a protruding tongue. Individuals with Down syndrome also have an increased risk of certain medical conditions such as congenital heart defects and thyroid problems. Prenatal screening and diagnostic tests can identify Down syndrome in utero. Lifelong medical care is important to monitor development, screen for associated conditions, and support quality of life.
This document discusses Down syndrome, including its causes, features in newborns, diagnosis, and management. Down syndrome results from extra genetic material from chromosome 21, which can occur through trisomy 21, mosaicism, or translocation. Affected newborns commonly have hypotonia, slanted eyes, and other physical signs. Prenatal screening and testing can detect Down syndrome. Early intervention aims to support development and address any health issues.
Down syndrome is a genetic disorder caused by the presence of a third copy of chromosome 21. It is characterized by delayed physical and intellectual development. Affected individuals typically have mild to moderate intellectual disabilities and characteristic facial features such as a flat nasal bridge. While signs and symptoms vary, early intervention can help maximize development. Prenatal screening and testing can detect Down syndrome, but the only definitive test is chromosome analysis after birth. Lifelong support is important for managing associated medical issues.
The document discusses Down syndrome, which is caused by trisomy of chromosome 21 resulting in 47 total chromosomes instead of the typical 46. Individuals with Down syndrome have increased risk based on advanced maternal age and are more likely to have certain physical traits like a flat face and short hands. The condition was first described in 1866 and its genetic basis was discovered in 1930. Current research uses mouse models to study specific genes on chromosome 21 that may contribute to Down syndrome phenotypes.
This study examined the association between fingerprint patterns on the right and left second digits and intelligence quotient (IQ) level in 342 Iranian adolescents. The adolescents were divided into three groups based on their IQ scores: a talented group with IQs over 120, a normal group with IQs of 70-120, and a learning disabilities group with IQs below 70. The researchers found some significant differences in fingerprint patterns between the groups on the right second digit, but no significant differences on the left second digit. The study supports an association between some fingerprint patterns on the right second digit and IQ level in adolescents. Further research with larger sample sizes is recommended.
The document summarizes a study on dermatoglyphic patterns in 137 patients diagnosed with infantile autism. The study found a broad range of dermatoglyphic anomalies in patients with autism compared to healthy controls. Specifically:
1) Patients with autism had higher frequencies of arch patterns and lower frequencies of loop patterns on fingers compared to controls.
2) Patients also showed atypical palmar dermatoglyphic patterns including differences in ridge count patterns and triradius positions.
3) Both digital and palmar dermatoglyphic anomalies occurred more frequently in autism patients of both sexes and were often more pronounced on the left hand. These dermatoglyphic distortions
This study examined the relationship between dermatoglyphic patterns, fluctuating asymmetry, and positive and negative symptoms in schizophrenia. 72 schizophrenia patients and 72 controls were studied. Schizophrenic subjects had significantly lower ridge counts in both hands compared to controls. Fluctuating asymmetry was significantly higher in schizophrenic subjects. Schizophrenics with predominantly negative symptoms showed significantly lower ridge counts and higher fluctuating asymmetry than schizophrenics with positive symptoms. The findings support the hypothesis that schizophrenia could be related to central nervous system developmental abnormalities.
1) The study analyzed dermatoglyphic patterns such as digital patterns, ATD angles, ridge counts, and triradii on the hands of 30 prostate cancer patients and 30 normal subjects in Nigeria.
2) Significant differences were found between the two groups in terms of higher mean A-B and B-C ridge counts, and lower mean ATD angles, in the prostate cancer patients compared to normal subjects.
3) These characteristic dermatoglyphic patterns associated with prostate cancer could potentially provide a tool for early diagnosis of prostate cancer among Nigerians.
This document discusses the future of biometrics technologies and their potential applications. It provides an overview of current biometrics technologies including facial scanning, iris scanning, retina scanning, finger scanning, and hand scanning. The document also discusses expanding these technologies to assess character and medical diagnoses by recognizing patterns in biometric scans. Potential applications mentioned include health care, education, employment, security, and government/military uses.
Autism is group of child developmental disabilities that can cause social, communication and behavioural challenges in Kids. Giostar provides Stem Cell Treatment for Autism call us at +91 7043008890.
This presentation contains detailed knowledge about Down's Syndrome its types, clinical presentation, diagnosis, medical and physio therapeutic management of the condition.
Down syndrome is a condition in which a person has an extra chromosome. Chromosomes are small “packages” of genes in the body. They determine how a baby’s body forms and functions as it grows during pregnancy and after birth. Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is ‘trisomy.’ Down syndrome is also referred to as Trisomy 21. This extra copy changes how the baby’s body and brain develop, which can cause both mental and physical challenges for the baby.
This document provides details on the case of an 8 month old female child named Azma who presented with recurrent cold, cough, loose motions, and rapid breathing. It summarizes her birth history, developmental milestones, family history, clinical features, genetic causes, common health issues, diagnostic criteria, management, and prognosis of Down syndrome.
The document discusses the different types of autism spectrum disorders including Asperger's syndrome, Kanner's syndrome, pervasive developmental disorder, Rett's syndrome, and childhood disintegrative disorder. It describes the characteristics of each type, such as difficulties with social and communication skills, repetitive behaviors, and sensory processing. The causes of autism are not entirely known but are believed to involve genetic and environmental factors. While there is no cure for autism, early intervention and treatment tailored to the individual can help children develop their skills and manage symptoms.
Down Syndrome is the most common chromosomal abnormality affecting children today. It occurs in approximately 1 in 800 to 1,000 births and is caused by the presence of an extra copy of chromosome 21. Individuals with Down Syndrome often have intellectual disabilities and are at increased risk for certain medical conditions such as congenital heart disease, gastrointestinal abnormalities, hearing loss, thyroid disorders, and periodontal disease. Proper screening, monitoring, and management of associated health issues can help improve quality of life for those with Down Syndrome.
This document summarizes the clinical findings and neuropsychological assessments of three adolescent patients with Pontine Tegmental Cap Dysplasia (PTCD). All three patients presented with multiple cranial neuropathies including bilateral deafness, as well as feeding difficulties and hypotonia as infants. While their feeding difficulties resolved over time, they exhibited mild to moderate cognitive impairments, language deficits, and two showed mild behavioral issues. Brain imaging confirmed the abnormal bundle of fibres in the pons characteristic of PTCD. The outcomes suggest PTCD may have a more favorable long-term prognosis with borderline or normal cognition, and cochlear implants improved abilities for two patients.
Down syndrome is a genetic condition caused by trisomy of chromosome 21. It occurs in about 1 in 700 live births. Clinical features include intellectual disability, characteristic facial features such as a flat face, upward slanted eyes, and a protruding tongue. Individuals with Down syndrome also have an increased risk of certain medical conditions such as congenital heart defects and thyroid problems. Prenatal screening and diagnostic tests can identify Down syndrome in utero. Lifelong medical care is important to monitor development, screen for associated conditions, and support quality of life.
This document discusses Down syndrome, including its causes, features in newborns, diagnosis, and management. Down syndrome results from extra genetic material from chromosome 21, which can occur through trisomy 21, mosaicism, or translocation. Affected newborns commonly have hypotonia, slanted eyes, and other physical signs. Prenatal screening and testing can detect Down syndrome. Early intervention aims to support development and address any health issues.
Down syndrome is a genetic disorder caused by the presence of a third copy of chromosome 21. It is characterized by delayed physical and intellectual development. Affected individuals typically have mild to moderate intellectual disabilities and characteristic facial features such as a flat nasal bridge. While signs and symptoms vary, early intervention can help maximize development. Prenatal screening and testing can detect Down syndrome, but the only definitive test is chromosome analysis after birth. Lifelong support is important for managing associated medical issues.
The document discusses Down syndrome, which is caused by trisomy of chromosome 21 resulting in 47 total chromosomes instead of the typical 46. Individuals with Down syndrome have increased risk based on advanced maternal age and are more likely to have certain physical traits like a flat face and short hands. The condition was first described in 1866 and its genetic basis was discovered in 1930. Current research uses mouse models to study specific genes on chromosome 21 that may contribute to Down syndrome phenotypes.
This study examined the association between fingerprint patterns on the right and left second digits and intelligence quotient (IQ) level in 342 Iranian adolescents. The adolescents were divided into three groups based on their IQ scores: a talented group with IQs over 120, a normal group with IQs of 70-120, and a learning disabilities group with IQs below 70. The researchers found some significant differences in fingerprint patterns between the groups on the right second digit, but no significant differences on the left second digit. The study supports an association between some fingerprint patterns on the right second digit and IQ level in adolescents. Further research with larger sample sizes is recommended.
The document summarizes a study on dermatoglyphic patterns in 137 patients diagnosed with infantile autism. The study found a broad range of dermatoglyphic anomalies in patients with autism compared to healthy controls. Specifically:
1) Patients with autism had higher frequencies of arch patterns and lower frequencies of loop patterns on fingers compared to controls.
2) Patients also showed atypical palmar dermatoglyphic patterns including differences in ridge count patterns and triradius positions.
3) Both digital and palmar dermatoglyphic anomalies occurred more frequently in autism patients of both sexes and were often more pronounced on the left hand. These dermatoglyphic distortions
This study examined the relationship between dermatoglyphic patterns, fluctuating asymmetry, and positive and negative symptoms in schizophrenia. 72 schizophrenia patients and 72 controls were studied. Schizophrenic subjects had significantly lower ridge counts in both hands compared to controls. Fluctuating asymmetry was significantly higher in schizophrenic subjects. Schizophrenics with predominantly negative symptoms showed significantly lower ridge counts and higher fluctuating asymmetry than schizophrenics with positive symptoms. The findings support the hypothesis that schizophrenia could be related to central nervous system developmental abnormalities.
1) The study analyzed dermatoglyphic patterns such as digital patterns, ATD angles, ridge counts, and triradii on the hands of 30 prostate cancer patients and 30 normal subjects in Nigeria.
2) Significant differences were found between the two groups in terms of higher mean A-B and B-C ridge counts, and lower mean ATD angles, in the prostate cancer patients compared to normal subjects.
3) These characteristic dermatoglyphic patterns associated with prostate cancer could potentially provide a tool for early diagnosis of prostate cancer among Nigerians.
This document discusses the future of biometrics technologies and their potential applications. It provides an overview of current biometrics technologies including facial scanning, iris scanning, retina scanning, finger scanning, and hand scanning. The document also discusses expanding these technologies to assess character and medical diagnoses by recognizing patterns in biometric scans. Potential applications mentioned include health care, education, employment, security, and government/military uses.
The document describes a laboratory exercise for students to analyze fingerprint patterns, total ridge counts, and angles of triradii deviation (ATD) among classmates and individuals with Down syndrome to study the genetics underlying these dermatoglyphic traits. Students will take fingerprints and palm prints, classify patterns, count ridges, measure ATD angles, and compare results between individuals to explore polygenic inheritance and developmental influences on these quantitative traits.
The brain develops rapidly in early childhood as neurons form connections in response to stimuli and experiences. Early learning peaks between ages 3-10 but continues through life. Parents and caregivers play a critical role by providing loving, consistent care; talking and reading to infants and children; exposing them to music and physical activities; and mirroring behaviors to nurture. Positive experiences in early childhood help organize the brain and form the building blocks for human interactions, while neglect or trauma can cause later problems.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by difficulties with social interaction and communication, and restricted and repetitive behavior. The causes are both genetic and environmental. Genetically, ASD is highly heritable but heterogeneous, with many genes likely contributing. Environmentally, certain prenatal and perinatal factors like maternal infections may play a role. Neurologically, individuals with ASD often experience abnormal brain growth early in development, with increased brain volume and abnormalities in frontal, temporal and limbic regions.
Autism is a developmental disorder characterized by impaired social interaction and communication skills, as well as restricted and repetitive behaviors. It typically emerges in the first 3 years of life. Males are diagnosed with autism 3-7 times more often than females. While its exact causes are unknown, autism is considered to have a strong genetic component. Diagnosis involves assessing social, communication and behavioral criteria. Treatments aim to improve core symptoms and functions through educational, behavioral and medical interventions.
Autism spectrum disorder is a neurodevelopmental condition characterized by impairments in social communication and restricted, repetitive behaviors. It is a highly heritable and heterogeneous condition. The document discusses the history of autism, epidemiology, etiology including genetic and environmental factors, clinical features, diagnosis, and treatment. Autism is typically diagnosed by age 2 and is more common in boys than girls. While the exact causes are unknown, both genetic and environmental factors are thought to play a role in its development.
This document discusses the role of school psychologists in identifying autism spectrum disorders (ASD). It covers:
1) School psychologists need to be more vigilant in screening for ASD symptoms among students and better prepared to identify potential cases and make referrals for assessment.
2) They should also be prepared to assist in the diagnostic process for ASD.
3) The document outlines Filpek et al.'s algorithm for diagnosing autism, which involves case finding, screening, evaluation, diagnosis, and referral for services. School psychologists are important players in following this process.
SB2.ppt autism spectrum disorders part 02RachidBen15
This document provides an overview of autism spectrum disorders (ASD) including diagnostic assessment and the school psychologist's role in identification. It discusses the evolution of the term "autism" and contemporary classifications. School psychologists need to be vigilant for ASD symptoms, prepared to screen and refer students, and assist in the diagnostic process. The causes of ASD are complex and likely involve genetic, neurological, and environmental factors interacting in individuals with a biological susceptibility.
Autism spectrum disorder is a neurodevelopmental condition characterized by difficulties with social interaction and communication, as well as restrictive and repetitive behaviors. It affects areas of the brain related to social skills, language, and flexibility. While the exact causes are unknown, genetic and environmental factors may play a role. Symptoms can range from mild to severe and vary by individual. Research is ongoing to better understand the condition and how the autistic brain differs from others. This course helped the student gain a deeper understanding of autism to better help patients.
Pediatric schizophrenia (childhood onset schizophrenia)Zeinab EL Nagar
Childhood-onset schizophrenia (COS) is a rare and severe mental disorder characterized by a deterioration of thinking, motor, and emotional processes in children under 18. Diagnosis is based on behaviors observed by caretakers and the same DSM criteria used for adults. COS is typically preceded by a prodromal phase involving school problems, social withdrawal, and disorganized behavior. Auditory hallucinations are a common symptom, and delusions can cause irrational actions. Successful treatment involves pharmacology, psychosocial interventions, and psychoeducation to help patients and families understand the illness. Prognosis is generally poorer the earlier onset occurs but can be better if intelligence was higher premorbidly and family cooperates with treatment.
This document discusses autism spectrum disorder (ASD). It defines ASD as a lifelong developmental disability characterized by impairments in social interaction and communication, as well as restricted and repetitive behaviors. The document summarizes key findings about the prevalence and diagnosis of ASD according to the DSM-IV and DSM-5. It also discusses common symptoms, screening tools, potential neurological abnormalities, motor deficits associated with ASD, and the benefits of physical activity programs for individuals with ASD.
Dermatoglyphic anomalies and neurocognitive deficits in siblingCA. Sanjay Ruia
1) Sibling pairs discordant for schizophrenia spectrum disorders were assessed for neurocognitive performance and dermatoglyphic anomalies.
2) Affected siblings performed significantly worse on tests of executive function, set shifting, and attention compared to their unaffected siblings.
3) Affected siblings also had a greater number of dermatoglyphic anomalies including abnormal palmar flexion creases and ridge dissociations.
4) However, no significant association was found between dermatoglyphic anomalies and neurocognitive deficits in the affected siblings, suggesting a role for genetic or late environmental factors in the origin of their cognitive impairments.
This document provides information on Fragile X syndrome including:
- It is the most common inherited cause of intellectual disability and is an X-linked condition.
- The prevalence is 1 in 4000 males and 1 in 4000-6000 females who have the full mutation.
- Physical characteristics can include prominent ears, long narrow face, enlarged testes in males, and sensory or behavioral issues.
This document provides information on Down syndrome including:
- Down syndrome is a genetic condition caused by trisomy 21 and has a prevalence of 1 in 800-1000 live births.
- Physical characteristics include refractive errors like hyperopia and astigmatism as well as binocular vision issues like strabismus.
- Recent studies have found that bifocals can effectively treat the reduced accommodation often seen in individuals with Down syndrome.
The document provides information about Autism Spectrum Disorder (ASD) including:
- ASD is a complex developmental disability that causes problems with social interaction and communication. Symptoms usually start before age 3.
- Disorders included in the autism spectrum are Autistic Disorder, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified.
- There are no known cures for ASD but treatments aim to lessen symptoms and help people gain life skills.
The document discusses autism spectrum disorder (ASD), including that it is a neurodevelopmental disorder characterized by impairments in social interaction and communication as well as restrictive and repetitive behaviors. ASD can range from mild to severe and includes conditions like autism, Asperger's syndrome, and pervasive developmental disorder. While the exact causes are unknown, ASD is known to have both genetic and environmental risk factors.
This document provides information on intellectual disability (ID), including definitions, levels of severity, comorbid disorders, risk factors, causes, and treatment with psychotropic medications. Key points include:
- ID is defined by deficits in both IQ (70 or below) and adaptive functioning. It ranges from mild to profound depending on IQ scores.
- The most common causes are Down syndrome, Fragile X syndrome, and fetal alcohol syndrome, together accounting for 30% of cases.
- Risk factors include heredity, early embryonic alterations, environmental influences, and pregnancy/birth complications.
- Common comorbid disorders are ADHD, mood disorders, and autism spectrum disorders. Stimulants and
Autism is a neurodevelopmental disorder characterized by difficulties with social interaction and communication. It has a strong genetic component, with heritability estimates ranging from 40-80%. While hundreds of genes have been implicated, no single gene accounts for more than 1-3% of cases. Both rare and common genetic variants, as well as environmental factors, contribute to autism risk. The causes are highly heterogeneous and complex. Understanding the underlying genetics may help lead to improved diagnosis, treatment and prevention.
This document provides an overview of autism spectrum disorder (ASD). It discusses the epidemiology, etiology, classification, course, prognosis, and treatment of ASD. Some key points include:
- ASD is a neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors.
- The prevalence of ASD is approximately 1 in 160 children worldwide. Boys are diagnosed with ASD 4 times more often than girls.
- The causes of ASD are complex and not fully understood but likely involve both genetic and environmental factors.
- Treatment aims to reduce disruptive behaviors and promote skills in areas like language, communication, and self-care. Educational, pharmacological, and psychosocial approaches
This document provides information on autism spectrum disorders including:
- A brief history noting early descriptions by Kanner and Maudsley.
- Epidemiology showing prevalence of 2 per 1000, higher rates in males, and associations with intellectual disability.
- Etiology discussing theories including genetic, neurological, immunological and perinatal factors.
- Clinical features such as impairments in social skills, communication deficits, stereotyped behaviors and sensory issues.
- Diagnostic classifications including autism, Asperger's syndrome, and other conditions under the pervasive developmental disorder umbrella.
Crimson Publishers-A Discourse about Autism Spectrum Disorders from the Aspec...CrimsonpublishersMedical
A Discourse about Autism Spectrum Disorders from the Aspect of Gender Relevancies of Biopsychology and Brain Research by Lehel Simon in Research in Medical & Engineering Sciences
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The study examined dermatoglyphic parameters such as fingerprint patterns, ridge counts, and atd angles in 100 patients with pulmonary tuberculosis compared to 100 healthy controls. It found whorl patterns were predominant in patients (56.6%) compared to controls (23.8%), while loop patterns decreased. Total and absolute finger ridge counts were significantly higher in patients. The atd angle was also significantly narrower in patients. This suggests dermatoglyphic analysis may help in the diagnosis of pulmonary tuberculosis.
Dermatoglyphics in diabetes mellitus of type 2CA. Sanjay Ruia
The document discusses a study analyzing dermatoglyphic patterns on the palms of 190 Romanian patients with type 2 diabetes mellitus (T2DM). The results found significant pathological dermatoglyphic distortions and anomalies in the T2DM patients compared to controls. Specifically, over 55% of patients had a partial suppression of line C, which was more common in women at 38% compared to 33% in men. While individual dermatoglyphic distortions may serve as markers for early T2DM diagnosis, two differences in overall palm patterns allow differentiation of T2DM from type 1 diabetes mellitus.
Dermatoglyphics in diabetes mellitus of type 2CA. Sanjay Ruia
The document discusses a study analyzing dermatoglyphic patterns on the palms of 190 Romanian patients with type 2 diabetes mellitus (T2DM). The results found significant pathological dermatoglyphic distortions and anomalies in the patients compared to a control group. Specifically, over 55% of patients showed a partial suppression of line C, which was more common in women at around 38%. This and other dermatoglyphic markers could help identify individuals at risk for T2DM.
Dermatoglyphic investigations on infantile autismCA. Sanjay Ruia
This document summarizes the findings of a study comparing dermatoglyphic (fingerprint) patterns in two groups of people with infantile autism. The 2008 group consisted of 207 individuals (104 boys and 103 girls), more than the 2003 group of 137. Several fingerprint distortions were found at significantly different rates between the groups, such as increased radial arcs and reduced fingerprint ridge spacing, suggesting an increased pathological load in the 2008 group. Sex differences in distortion frequencies were consistent between groups. Most distortions occurred more often on the left hand. Overall, distortion rates differed from a reference group, indicating genetic/teratogenic factors influence fingerprint development in autism before birth. The results help characterize dermatoglyphic indicators for diagnosing
The document discusses brain development in young children. It makes three key points:
1) A child's environment and experiences have a huge impact on how their brain cells connect, with loving interactions stimulating growth. During early childhood, the brain undergoes rapid growth and pruning of unused connections.
2) "Windows of opportunity" exist when specific skills like language and motor skills are most easily learned. Stimulating activities during these periods helps the brain develop important circuits.
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In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
MATATAG CURRICULUM: ASSESSING THE READINESS OF ELEM. PUBLIC SCHOOL TEACHERS I...NelTorrente
In this research, it concludes that while the readiness of teachers in Caloocan City to implement the MATATAG Curriculum is generally positive, targeted efforts in professional development, resource distribution, support networks, and comprehensive preparation can address the existing gaps and ensure successful curriculum implementation.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
Thinking of getting a dog? Be aware that breeds like Pit Bulls, Rottweilers, and German Shepherds can be loyal and dangerous. Proper training and socialization are crucial to preventing aggressive behaviors. Ensure safety by understanding their needs and always supervising interactions. Stay safe, and enjoy your furry friends!
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
1. THE JOURNAL OF PREVENTIVE MEDICINE
2003; 11 (1): 11-17
PATHOLOGY OF DERMATOGLYPHICS IN INFANTILE AUTISM
Ana Ţarcă1, C. Barabolski2
1. Department of Anthropology - Iaşi Branch of the Romanian Academy
2. ,,Socola” University Clinical Hospital of Iaşi
Abstract. The authors present the results of a study on digitopalmary dermatoglyphies of
patients diagnosed with infantile autism. 137 subjects (67 boys and 70 girls) with 274 finger
and palmar prints, residents in country’s eastern territory have been investigated. The
dermatoglyphic digito-palmary picture revealed a broad range of anomalies or distortions
(associated with severe clinical features) both as the frequency of some of the digital or
palmary characteristics and their distribution by sex, laterality and fingers, which differentiate
significantly these people from the normal population. Occurring both in boys and girls, on
both hands but with priority on the left ones, these distortions contribute to a more complete
knowledge of the dermatoglyphic nomogram on the basis of which infantile autism could be
diagnosed early. The present study is the first one – at national level – devoted to such
aspects.
Key words: dermatoglyphics, infantile autism, anomalies or distortions
Rezumat. Lucrarea cuprinde un studiu al dermatoglifelor digito-palmare prezente la pacienţi
cu autism infantil (67 băieţi şi 70 fete) de vârste cuprinse între 2,5 şi 18 ani, de la care s-au
recoltat 274 amprente. Se constată că, tabloul dermatoglific digito-palmar al pacienţilor cu
autism infantil prezintă o gamă largă de anomalii sau distorsiuni (cu grave implicaţii clinice),
atât sub aspectul frecvenţei unora dintre caracteristicile digitale sau palmare cât şi al
distribuţiei lor în funcţie de sex, lateralitate şi degete, prin care afectaţii se diferenţiază
semnificativ de populaţia normală din care provin. Prezente atât la băieţi cât şi la fete şi pe
ambele mâini ale afectaţilor dar cu precădere pe cea stângă, distorsiunile evidenţiate sunt o
contribuţie la cunoaşterea nomogramei dermatoglifice de diagnoză a autismului infantil, având
în vedere că studiul de faţă este primul de acest gen la nivel naţional.
Cuvinte cheie: dermatoglife, autism infantil, anomalii sau distorsiuni
INTRODUCTION own hermetic world dominated by
Known also as the ,,Kanner’s unreal images, obsessions and feelings
Syndrome”- the name of its discoverer and pronominal reversal, rituals and
(1943), the infantile autism is defined compulsive phenomena (1-4).
nowadays as a syndrome characterized Once lacking its communicative
by a large spectrum of neuropsychic function, the child’s language becomes
disorders, manifested by: delayed speaking, a soliloquic, talking to himself
incapacity of verbal communication, stereotypically, producing meaningless
inability of establishing and developing sounds and expressions, repeating ad
contacts with the other (close persons literam and evoking ceaselessly past
being included), the shrink into one’s
11
2. Ana Ţarcă, C. Barabolski
events, related to nothing, a state chromosome syndrome and with
named ,,echolalia”. Tuberous sclerosis (2,6).
The syndrome, which is usually Taking into consideration the multiple
installed around the age of 30 months, forms of the manifestations characterizing
rarely earlier or later, is in quite the disease, credit has come to be
various forms, from mild - more or given to the idea that each autistic
less similar to a normal child - to very child’s is an unique case, capable of
severe ones (1,2,4,5). The first providing a multitude of symptoms for
category includes the Asperger each psychic function, taken separately
Syndrome (2-4), assuming solely the (1,2,7).
presence of some autistic elements, As to the etiology of autism, several
such as: anxiety, reduced socialization, hypotheses - including multiple causes
utilization of the language exclusively of the disease - have been advanced
for personal benefits, child’s intellect (1,4,7,8). The most widely accepted
being not affected at all, and the Ret today one supports the organic nature
Syndrome (1,2), affecting almost of autism, and assumes certain
exclusively little girls. It is structural and functional anomalies at
characterized, apart from some bony the level of the cerebral hemispheres -
distrophies, sight disorders, height and especially in the parietal zone
weight hypotrophy, or cortical (responsible for hearing, speaking and
anthropies, by certain autistic language) in the temporal zone
manifestations, such as: slow diction, (known as regulating the formation of
absence of social communication, social and emotional habits), as well as
repeated stereotype movements. The at the level of the Calous Body,
severe forms of infantile autism are through which the nervous impulses
associated - in most cases - with are transmitted from one cerebral
severe or moderate mental retardation, hemisphere to another. Actually, by
with epilepsy, dislexy, alalia, hearing magnetic nuclear resonance (MRI) at
less, enuresis or double incontinence, brain level (1) a low nervous activity
sometimes with the Fragil - X in the above mentioned regions have
chromosome syndrome or Martin Bell’s been detected. Such anomalies present
disease, or with a very rare genetic at the level of autistic brain may be
disease - namely, tuberous sclerosis. inherited (especially in the case of
Consequently, it is appreciated family forms of autism), or they may
nowadays that about 75% of autistic appear either during prenatal
persons evidence mental retardation, development (more exactly, in the first
of which 15%-20% with very severe three months of embrionary life, when
forms (IQ - below 34); almost 1 of 3 epidermal papillary ridges are also
persons are stricken by epileptic forming), being provoked by viral or
crises, while, for about 10% of them bacterian infections, metabolic
(boys, especially) the disease is disorders etc., or in perinatal periods.
associated with the Fragil - X
12
3. PATHOLOGY OF DERMATOGLYPHICS IN INFANTILE AUTISM
As to autism’s substrate and genetic anxiety, dislexy, double incontinency.
mechanism research is in progress In the most of cases (52.55%) the
(2,4,5,9), sustained efforts being made disease was accompanied by moderate
by specialists for discovering the mental deficiency, alalie, enuresis,
genes responsible for the disease, in hypoacusy. Some patients had
view of a possible, future elimination epilepsy (10.95%). Over 75% of
from the genetic code. Until then, people have been considered with
however, it is absolutely necessary to disability of first degree, which
establish some methods and assumes an advanced stage of
techniques for an early identification neuropsychic and physiological
of children in danger of autism, so that degeneration, suggestively illustrated -
an adequate therapy should be applied as we shall see in the following - by
prior to the manifestation of any the broad pathological charge of their
symptoms. As the dermatoglyphic dermatoglyphic picture, too.
studies, performed on patients suffering For all indicators of dermatoglyphic
from Down syndrome, congenital pathology put into evidence, sexual
deafness, or with heart congenital dimorphism and bilateral differences
malformations, severe ophtalmologic had been also considered, the results
disorders or epilepsy (9-13) put into being compared with those of controls
evidence the importance of (normal population) from the same
dermatoglyphic indicators for an early region (a group of 200 subjects: 100
diagnosis, their application had been men and 100 women).
considered as beneficial also in The working methods have been those
infantile autism. currently employed in studies of
Consequently, a dermatoglyphic study pathologic dermatoglyphy (9,11,14).
on a group of autistic patients,
residents in eastern territory, has been RESULTS AND DISCUSSION
developed. The analysis and statistic processing
of the dermatoglyphic data of the
MATERIAL AND METHODS patients with infantile autism have
137 patients with infantile autism (67 shown that both their finger and
boys and 70 girls) aged between 2.5 palmary picture show an ample and
and 18 years, all residents in eastern strong pathological charge,
territory of Romania, have been suggestively illustrated by a multitude
investigated in the Mental Health of distortions with deep clinical
Laboratory of Iassy. significance, being an expression of
The medical records of the patients - their advanced degree of neuropsychic
whose disease began to manifest and physiological degeneration.
around the age of 2 years - showed At the level of the whole sample, such
that, in 36.50% of the cases, autism anomalies are deviations in the
was associated with a severe mental frequency of some of the finger or
deficiency (IQ below 34), with palmar dermatoglyphic characteristics
13
4. Ana Ţarcă, C. Barabolski
from the values of normal population on the right hand of both sexes having
from which the subjects come, and its major incidence on fingers IV and V.
also upsetting from their classical • Palmary dermatoglyphic
distribution line, as a function of sex, distortions
laterality or fingers. A large part of A broad range of distortions, quite
such distortions had been reported severe as to their pathological
also, for other European groups of significance (9,11,12,13); has been
autistic patients (6,8,10), as well as in provided by palmary picture. The first
other severe genetic disorders one, refers to the modification of the
(7,9,10,12) - in different ratios – fact classical sequence of the true
which explains their large clinical patterns’ frequency in palm’s five
implications. compartments, that is IV > Hp > III >
• Digital dermatoglyphic distortions Th/I > II instead of IV > III > Hp >
Patients with infantile autism show a Th/I > II which is the normal case.
significantly higher frequency for Such a situation is induced by the
arches (A) and a lower one for loops substantial reduction of pattern’s
(L) on all fingers, comparatively with percentages in the interdigital space
the control group (table 1). If, for the III, up to 24.09%, comparatively with
normal population, the two main 36.09% - recorded on the control
patterns are predominant at girls and group, the difference being
on the left hand, in these patients they statistically significant (p < 0.02). This
were more frequently at boys and on anomaly, associated with the other
the right hand (the last one, for loops, two, equally important as to their
exclusively). malformative effects, consists in the
The arches, usually present on the increase (over two fold) of partial and
second and third finger, and very total supression of C line (Cx and
rarely represented on the others, Co, respectively) compared with the
records quite high percentages on the controls. Cx was more frequent in
fourth and fifth finger, and especially boys, while Co in girls; both prevailed
on the first finger of the left hand on left palms, the tendencies being
(15.7% for girls and 10.45% for boys); similar to those of the control group
many of them had here a radial instead (table 1).
of an ulnar orientation - a peculiarity Significantly higher frequencies have
considered as a strong ,,malformative been found also for: the presence of
stigmate” for carriers (9,11). the loop with ulnar orientation (LU)
A last dermatoglyphic anomaly at the and of 2, 3 or 4 triradia in the same
digital level refers to the significant palm (tt’, tt’t’’, etc); the absence of
increase of raketoid loops ratio, the axial triradius t in the palm (tΟ)
through which the patients of the both and finishing of line T’s course in
sexes are considerably differential from fields 11 and 12 instead of 13 (all of
the control group (p < 0.01); it is a them at the level of palm’s
distortion more frequent in girls and Hypothenary); for the arrangement
14
5. PATHOLOGY OF DERMATOGLYPHICS IN INFANTILE AUTISM
of the papillary ridges as a dense and or the Simian Line. The differences
very dense network in the Thenar/I; between the two groups concerning
for reducing the distance between the mentioned distortions are
triradia a and b, limiting the supported statistically by a p value of
interdigital space II, much lower than < 0.05, especially when considering
the normal average value of 21 mm - the male and female series, on whole
for women and, of 24 mm - for men, (table 1).
and for the transverse palmary sulcus
Table 1. Frequencies of digital and palmary distortions in infantile autism group
comparatively with normal population
Digital and Infantile autism (137) Control (200) p value
palmary Boys Girls Boys + Boys Girls Boys + Boys Girls Boys +
distortions (%) Girls Girls Girls
A on all fingers 10.60 10.00 10.29 2.50 6. 20 4.35 < 0.03 NS 0.03
L>R L>R L>R L>R L>R L>R
L on all fingers 61.19 59.71 60.44 67.00 75.20 71.10 NS < 0.03 0.04
R>L R>L R>L L>R L>R L>R
Raketoid type 8.65 9.71 9.10 R - - - 0.01 0.01 < 0.01
loops R>L R>L >L
LU in Hp 11.95 7.86 9.85 3.90 2.63 3.26 0.05 NS < 0.02
L>R L>R L>R L>R L>R L>R
tt’, tt’t’’, etc. 27.62 36.42 32.11 15.80 17.92 16.86 NS < 0.01 0.01
R>L R>L R>L R>L R>L R>L
t0 2.24 7.14 4.75 - - - NS < 0.01 < 0.01
L>R L>R L>R
T11 and T12 32.09 28.57 30.30 2.80 3.51 3.15 < 0.01 < 0.01 < 0.01
instead of T13 L>R L>R L>R L>R L>R L>R
Dense and
very dense 29.85 58.57 44.52 10.90 16.91 13.95 0.01 < 0.01 < 0.01
network in Th/I L=R L>R L>R L>R L>R L>R
a-b < than 24 mm 58.39 62.04 60.22 9.80 7.20 8.50 L
in M R>L R>L R>L L>R L>R >R < 0.01 <0.01 < 0.01
21 mm in F
Cx 36.56 30.30 33.21 16.90 14.50 15.70 0.01 0.02 0.01
L>R L>R L>R L>R L>R L>R
Co 5.22 10.00 7.66 2.10 3.20 2.60 NS 0.05 0.05
L>R L>R L>R L>R L>R L>R
Transverse 11.94 6.43 9.12 4.10 2.30 3.20 0.05 NS 0.03
palmary Sulcus L=R L>R L>R L>R L>R L>R
Table 1 data show that, out of the 9 network from Th/I, Co and the much
palmary distortions occurring in more reduced a-b distance are
infantile autism, LU from Hp, T11 and present to girls - a dimorphic tendency
T12, Cx and the palmar Sulcus are which, apart from some insignificant
more frequent to boys, while tt’t’’, exceptions, was present in the control
etc, t0, the dense and very dense group, as well.
15
6. Ana Ţarcă, C. Barabolski
Of the two hands, most of the palmary maintain the tendencies occurring
anomalies of patients with autism were in the normal population.
more frequent on the left palm (with 4. These results could be of use for an
the exception of tt’t’’, etc., and of the early identification of infantile
much lower a-b distance), being autism in order to establish an
recognized as carriers of the majority adequate therapy.
of ,,malformative stigmata” in other
maladies, too (8,9,11,14). With the REFERENCES
only one exception (the reduced a-b 1. xxx: American Psychiatric Association
distance) these bimanual differences (APA): Diagnostic and Statistical
agree, with those of the control group, Manual of Mental Disorders, Fourth
too (table 1). Edition, Washington D.C., 1994.
2. Meilă P, Milea Şt: Textbook of
pediatrics, Med. Publ. House Bucureşti,
CONCLUSIONS 1988, 6: 340-346 (in Romanian).
1. The dermatoglyphic investigations 3. Uta F: Autism and Asperger
performed on patients with infantile Syndrome. Cambridge Univ. Press,
autism, have put into evidence 1997, 37-183.
multiple modifications (either 4. xxx: World Health Organization
anomalies or distortions) with deep (WHO): International Classification
pathological significance, both in of Diseases, Chapt. V, Mental and
the digital and - especially - in the Behavioural Disorders. Geneva,
palmary picture (up to eight for 1990, 270-287.
each patient) being present - in 5. Bowman EP: Asperger’s Syndrome
and Autism. British Journal of
most cases - on carriers’ both
Psychiatry, 1983, 143: 261-265.
hands. 6. Langenbeck W, Varga I, Hausman I:
2. On the whole group, for all The Predictive Value of Dermato-
distortions put into the light, glyphics in the Diagnosis of FRA (X)-
significantly higher ratios have Positive Martin Bell Syndrome
been found comparatively with the (MBS), American Journal of Med.
control group suggesting that the Genet., 1988, 169-175.
causal factors involved in the 7. Wing L: Language, Social and
development of autistic manifestations Cognitive Impairments in Autism and
had been active during the first Severe Mental Retardation. Journal of
three or four months of intrauterine Autism and Development Disorders,
1981, 11: 31-44.
life, when the epidermal papillary
8. Sank D, Sank BD: Finger Prints and
ridges were finished up. Laterality Preferences of Early Onset
3. The digital anomalies are mostly Autism. Birth Defects, Original
accompanied by some significant Article Series, 1979, XV, 6: 678-695.
deviations from the classical line of 9. Schauman B, Alter M: Dermatoglyphics
the sexual dimorphism, of the in Medical Disorders. Springer Verlag,
bilateral differences, or distribution New-York-Heidelberg-Berlin, 1976, 253.
on fingers; the palmary ones
16
7. PATHOLOGY OF DERMATOGLYPHICS IN INFANTILE AUTISM
10. Ţarcă A: The population dermatogyiphics 13. Ţarcă A, Barabolski C: Contributions to
in three Romanian provinces. Thesis, the Dermatoglyphic Diagnosis of
Univ. of Iaşi 1995, 171-217 (in Epilepsy. Journal of Preventive
Romanian). Medicine, 2002, 10 (2): 28-35.
11. Ţarcă Ana: La valeur diagnostique 14. Loesch DZ: Dermatoglyphics Methods
des dermatoglyphes. Jurnal de in other Types of Malformations and
Medicină Preventivă, Iaşi, 1998, 6 (1): Diseases. Quantitative Dermatoglyphics,
11-24 (in Romanian). Oxford Univ. Press, 1983, 315-331.
12. Ţarcă A: Contribution a l’étude de la
pathologie des dermatoglyphes.
Anthropo, 2001 b, 51-60.
17