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DENTIGEROUS CYST WITH EMPHASIS ON ITS
COMPLICATIONS
PRESENTER:DR.KRISHNA MOHAN MDS
SYNOPSIS
CYST - 1) DEFINITION
2) CLASSIFICATION
3) PATHOGENESIS
DENTIGEROUS CYST -
DEFINITION
TERMINOLOGY
EPIDEMIOLOGY
CLASSIFICATION
CLINICAL FEATURES
RADIOLOGICAL FEATURES
HISTOLOGICAL FEATURES
INVESTIGATION
TREATMENT
COMPLICATIONS
RECENT ADVANCES
STAGES OF TOOTH DEVELOPMENT
• Bud stage
• Cap stage
• Bell stage –Early bell stage
-Late (or)advanced bell stage
CYST
A cyst is pathologic cavity
having fluid, semifluid, or
gaseous contents that are not
created by the accumulation of
pus; frequently, but not always,
is lined by epithelium .
KRAMER’S(1974)
TYPES OF CYST
TRUE CYSTS :
Cysts which are lined by
epithelium, E.g. Dentigerous
Cyst, Radicular Cyst, etc.
PSEUDO CYSTS :
Cysts which are not lined
by epithelium, E.g. Solitary
Bone Cyst, Aneurysmal Bone
Cyst,Traumatic bone cyst etc.
CLASSIFICATION (WHO 1992 )
WHO 2005
WHO 2017
SHEAR CLASSIFICATION
According to Shear cysts are classified under three main
headings:
I ) Cysts of the jaws
II) Cysts associated with the maxillary antrum
III Cysts of the soft tissues of the mouth, face, neck and salivary
glands.
CYSTS OF THE JAWS
EPITHELIAL-LINED CYST NON-EPITHELIAL-LINED CYSTS
ODONTOGENIC NON ODONTOGENIC
• Gingival cyst of infants
• Odontogenic keratocyst
• Dentigerous cyst
• Eruption cyst
• Gingival cyst of adults
• llateral
• periodontal cyst
• Botryoid odontogenic
cyst
• Glandular odontogenic
cyst
• Calcifying
odontogenic cyst
• Midpalatal raphe cyst of
infants
• Nasopalatine duct cyst
• Nasolabial cyst
• Inflammatory origin
• Radicular cyst, apical and
lateral
• Residual cyst
• Paradental cyst and
• juvenile paradental cyst
• Inflammatory collateral
cyst
• Solitary bone cyst
• Aneurysmal bone cyst
CYSTS ASSOCIATED WITH THE MAXILLARYANTRUM
• Mucocele
• Retention cyst
• Pseudocyst
• Postoperative maxillary cyst
CYSTS OF THE SOFT TISSUES OF THE MOUTH, FACE AND NECK
• Dermoid and epidermoid cysts
• Lymphoepithelial cyst
• Thyroglossal duct cyst
• Nasopharyngeal cyst
• Thymic cyst
SHAFERS CLASSIFICATION
DEVELOPMENTAL
CLASSIFICATION BASED
ON ETIOLOGY
CLASSIFICATION BY
TISSUE OF ORIGIN
Dentigerous cyst
Eruption cyst
Odontogenic keratocyst
Gingival (alveolar)
cyst of newborn
Gingival cyst of adult
Lateral Periodontal cyst
Calcifying odontogenic cyst
Glandular odontogenic cyst.
INFLAMMATORY
Periapical
Residual periapical
(radicular) cyst
Paradental cyst
DERIVED FROM
RESTS OF
MALASSE
DERIVED FROM
DENTAL LAMINA (
REST OF SERRES)
Periapical cyst
Residual cyst
Derived from
reduced enamel
epithelial
Dentigerous cyst
Eruption cyst
Odontogenic keratocyst
Gingival (alveolar) cyst of
newborn
Gingival cyst of adult
Lateral Periodontal cyst
Calcifying odontogenic
cyst
Glandular odontogenic
cyst.
PATHOGENESIS OF CYST
• INITIATION
• CYST FORMATION
• ENLARGEMENT
INITIATION
Initiation results in the proliferation of the developing
odontogenic epithelial cells and the formation of small
cavity
• Cell Rests of Malassez
• Reduced Enamel Epithelium
• Cell Rests of Serres (Dental Lamina)
CYST ENLARGEMENT
Harris (1974) Postulated the theories
1) Mural growth - Peripheral cell division
2) Hydrostatic –Accumulated contents
3) Bone resorbing factor
DENTIGEROUS CYST
• Latin word
• Denti -Tooth
• Gerous - Bearing or Producing
• Also called follicular cyst or
pericoronal cyst
• Developmental odontogenic cyst
of epithelial origin.
• Occurs in association with an
unerupted tooth
DEFINITION
• An odontogenic cyst
that surround the crown
of impacted
tooth,caused by fluid
accumulation between
the reduced enamel
epithelium and enamel
surface ,resulting in a
cyst in which the crown
is located within the
lumen.
PATHOGENESIS
THEORY :TOLLERS ET AL
• INTRAFOLLICULAR
• EXTRAFOLLICULAR
INTRAFOLLICULAR :
It may develop by the accumulation of
fluid either between the reduced enamel
epithelium and the enamel or within
enamel organ itself.
According to Atkinson(1976)
ACCORDING TO AL-TALABANI AND
SMITH(1980)
CLINICAL FEATURE
• AGE: first to third decades
• SEX: equal in both sex
• SITE: maxilla-33%, mandible-
67%
• most frequently located in angle
of mandible, canine region of
maxilla & mandible
• maxillary 3rd molar area , rarely
at anterior segment
• Usually painless , pain arise when
secondary infection occurs
• If untreated-swelling became
large
• Expansion of bone with
subsequent facial
asymmerty
• Pus may discharge in case
of secondary infection
RADIOLOGICAL FEATURE
• Well defined radiolucent area
• unilocular or multilocular
radiolucency encircle the crown
of unerupted tooth
• Central variety
• Lateral variety
• Circumferential variety
CENTRAL CIRCUMFERENTIAL
LATERAL
EXPANSION
ASSOCIATED DISEASE
Bilateral cysts are found in
association with Basal cell
nevus syndrome, Cleidocranial
dysplasia and a rare form of
amelogenesis imperfecta.
HISTOLOGICAL FEATURE
CYST LINED BY THIN KERATINISED EPITHELIUM
CYST LINED BY NON KERATINISED
EPITHELIUM
CYST LINED BY CILIATED COLUMNAR
EPITHELIUM
MUCOUS CELLS SEEN WIHIN THE
EPITHELIAL LINING
EPITHELIAL LINING CONTAINING
RUSHTON BODIES
INFLAMMED DENTIGEROUS CYST
DENTIGROUS CYST IN PRIMARY
DENTITION
• Frequently in children is low
• 10 years of age.
• Periapical inflammation from a
non-vital primary tooth
• The spread of periapical
inflammation may affect the germ
of permanent tooth and may
induce the formation of a cyst.
INVESTIGATION
FNAC BIOPSY
OPG CT BLOOD TEST
TREATMENT
• Enucleation
• Marsupialisation
• Removal of associated tooth
POTENTIAL COMPLICATION OF
DENTIGEROUS CYST
• Ameloblastoma
• Mucoepidermoid carcinoma
• Squamous cell carcinoma
RECENT ADVANCES
THANK YOU

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DENTIGEROUS CYST WITH EMPHASIS ON ITS COMPLICATIONS

  • 1. DENTIGEROUS CYST WITH EMPHASIS ON ITS COMPLICATIONS PRESENTER:DR.KRISHNA MOHAN MDS
  • 2. SYNOPSIS CYST - 1) DEFINITION 2) CLASSIFICATION 3) PATHOGENESIS DENTIGEROUS CYST - DEFINITION TERMINOLOGY EPIDEMIOLOGY CLASSIFICATION CLINICAL FEATURES RADIOLOGICAL FEATURES HISTOLOGICAL FEATURES INVESTIGATION TREATMENT COMPLICATIONS RECENT ADVANCES
  • 3. STAGES OF TOOTH DEVELOPMENT • Bud stage • Cap stage • Bell stage –Early bell stage -Late (or)advanced bell stage
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  • 8. CYST A cyst is pathologic cavity having fluid, semifluid, or gaseous contents that are not created by the accumulation of pus; frequently, but not always, is lined by epithelium . KRAMER’S(1974)
  • 9. TYPES OF CYST TRUE CYSTS : Cysts which are lined by epithelium, E.g. Dentigerous Cyst, Radicular Cyst, etc. PSEUDO CYSTS : Cysts which are not lined by epithelium, E.g. Solitary Bone Cyst, Aneurysmal Bone Cyst,Traumatic bone cyst etc.
  • 13. SHEAR CLASSIFICATION According to Shear cysts are classified under three main headings: I ) Cysts of the jaws II) Cysts associated with the maxillary antrum III Cysts of the soft tissues of the mouth, face, neck and salivary glands.
  • 14. CYSTS OF THE JAWS EPITHELIAL-LINED CYST NON-EPITHELIAL-LINED CYSTS ODONTOGENIC NON ODONTOGENIC • Gingival cyst of infants • Odontogenic keratocyst • Dentigerous cyst • Eruption cyst • Gingival cyst of adults • llateral • periodontal cyst • Botryoid odontogenic cyst • Glandular odontogenic cyst • Calcifying odontogenic cyst • Midpalatal raphe cyst of infants • Nasopalatine duct cyst • Nasolabial cyst • Inflammatory origin • Radicular cyst, apical and lateral • Residual cyst • Paradental cyst and • juvenile paradental cyst • Inflammatory collateral cyst • Solitary bone cyst • Aneurysmal bone cyst
  • 15. CYSTS ASSOCIATED WITH THE MAXILLARYANTRUM • Mucocele • Retention cyst • Pseudocyst • Postoperative maxillary cyst CYSTS OF THE SOFT TISSUES OF THE MOUTH, FACE AND NECK • Dermoid and epidermoid cysts • Lymphoepithelial cyst • Thyroglossal duct cyst • Nasopharyngeal cyst • Thymic cyst
  • 16. SHAFERS CLASSIFICATION DEVELOPMENTAL CLASSIFICATION BASED ON ETIOLOGY CLASSIFICATION BY TISSUE OF ORIGIN Dentigerous cyst Eruption cyst Odontogenic keratocyst Gingival (alveolar) cyst of newborn Gingival cyst of adult Lateral Periodontal cyst Calcifying odontogenic cyst Glandular odontogenic cyst. INFLAMMATORY Periapical Residual periapical (radicular) cyst Paradental cyst DERIVED FROM RESTS OF MALASSE DERIVED FROM DENTAL LAMINA ( REST OF SERRES) Periapical cyst Residual cyst Derived from reduced enamel epithelial Dentigerous cyst Eruption cyst Odontogenic keratocyst Gingival (alveolar) cyst of newborn Gingival cyst of adult Lateral Periodontal cyst Calcifying odontogenic cyst Glandular odontogenic cyst.
  • 17. PATHOGENESIS OF CYST • INITIATION • CYST FORMATION • ENLARGEMENT
  • 18. INITIATION Initiation results in the proliferation of the developing odontogenic epithelial cells and the formation of small cavity • Cell Rests of Malassez • Reduced Enamel Epithelium • Cell Rests of Serres (Dental Lamina)
  • 19. CYST ENLARGEMENT Harris (1974) Postulated the theories 1) Mural growth - Peripheral cell division 2) Hydrostatic –Accumulated contents 3) Bone resorbing factor
  • 20. DENTIGEROUS CYST • Latin word • Denti -Tooth • Gerous - Bearing or Producing • Also called follicular cyst or pericoronal cyst • Developmental odontogenic cyst of epithelial origin. • Occurs in association with an unerupted tooth
  • 21. DEFINITION • An odontogenic cyst that surround the crown of impacted tooth,caused by fluid accumulation between the reduced enamel epithelium and enamel surface ,resulting in a cyst in which the crown is located within the lumen.
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  • 23. PATHOGENESIS THEORY :TOLLERS ET AL • INTRAFOLLICULAR • EXTRAFOLLICULAR INTRAFOLLICULAR : It may develop by the accumulation of fluid either between the reduced enamel epithelium and the enamel or within enamel organ itself.
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  • 26. ACCORDING TO AL-TALABANI AND SMITH(1980)
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  • 28. CLINICAL FEATURE • AGE: first to third decades • SEX: equal in both sex • SITE: maxilla-33%, mandible- 67% • most frequently located in angle of mandible, canine region of maxilla & mandible • maxillary 3rd molar area , rarely at anterior segment • Usually painless , pain arise when secondary infection occurs • If untreated-swelling became large
  • 29. • Expansion of bone with subsequent facial asymmerty • Pus may discharge in case of secondary infection
  • 30. RADIOLOGICAL FEATURE • Well defined radiolucent area • unilocular or multilocular radiolucency encircle the crown of unerupted tooth
  • 31. • Central variety • Lateral variety • Circumferential variety CENTRAL CIRCUMFERENTIAL LATERAL
  • 33. ASSOCIATED DISEASE Bilateral cysts are found in association with Basal cell nevus syndrome, Cleidocranial dysplasia and a rare form of amelogenesis imperfecta.
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  • 36. CYST LINED BY THIN KERATINISED EPITHELIUM
  • 37. CYST LINED BY NON KERATINISED EPITHELIUM
  • 38. CYST LINED BY CILIATED COLUMNAR EPITHELIUM
  • 39. MUCOUS CELLS SEEN WIHIN THE EPITHELIAL LINING
  • 42. DENTIGROUS CYST IN PRIMARY DENTITION • Frequently in children is low • 10 years of age. • Periapical inflammation from a non-vital primary tooth • The spread of periapical inflammation may affect the germ of permanent tooth and may induce the formation of a cyst.
  • 45. POTENTIAL COMPLICATION OF DENTIGEROUS CYST • Ameloblastoma • Mucoepidermoid carcinoma • Squamous cell carcinoma
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