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Introduction To 
Cyst Classification 
& 
Dr V.RAMKUPaMthoApRhysiology 
CONSULTANT DENTAL 
&FACIOMAXILLARYSURGEON 
REG NO: 4118 TAMILNADU-INDIA( 
ASIA)
Cyst 
KRAMER-1974 
Definition : 
Cyst is defined as a pathological cavity having fluid, semi-fluid or 
gaseous contents that are not created by the accumulation of pus; 
frequently, but not always, is lined by an epithelium
Killey & Kay -1966 
• Cyst is an abnormal cavity in hard and soft 
tissues which contain fluid, semifluid, or 
gas and is often encapsulated and lined by 
epithelium.
CLASSIFICATION OF CYSTS 
(W.H.O) 
• A. EPITHELIAL 
1. Odontogenic 
a) Developmental: 
i ) Primordial cyst (Keratocyst) 
ii) Gingival cyst of infants 
iii) Gingival cyst of adult 
iv) Lateral periodontal cyst 
v) Dentigerous cyst (Follicular) 
vi) Eruption cyst 
vii) Calcifying odontogenic cyst
b. Inflammatory: 
i) Radicular cyst 
ii) Residual cyst 
iii) Inflammatory collateral cyst 
iv) Paradental cyst 
2. Non odontogenic Cysts: 
i) Nasopalatine duct cyst (incisive canal) 
ii) Median palatine, Median alveolar & 
Median mandibular cyst 
iii) Nasolabial cyst ( Nasoalveolar cyst) 
iv) Globulomaxillary cyst
B. NON EPITHELIAL 
CYSTS 
1. Simple bone cyst 
(Traumatic, Solitary, 
hemorrhagic bone cyst) 
2. Aneurysmal bone cyst
II) CYSTS ASSOCIATED 
WITH 
MAXILLARY ANTRUM • Benign mucosal cyst of maxillary antrum 
• Surgical ciliated cyst of maxilla.
III) CYSTS OF THE SOFT TISSUES 
OF THE MOUTH, FACE & NECK 
1) Dermoid and epidermoid cysts 
2) Branchial cyst (Lympho epithelial) 
3) Thyroglossal duct cyst 
4) Anterior median lingual cyst 
5) Oral cyst with gastric and intestinal epithelium 
6) Cystic hygroma 
7) Cysts of the salivary glands 
8) Parasitic cysts: Hydatid cyst: Cysticercus 
Cellulosal
DIAGRAM OF ODONTOGENIC CYSTS BASED ON 
CLINICAL AND RADIOGRAPHIC FEATURES
CYST 
PATHOGENESIS 
INITIATION 
CYST FORMATION 
ENLARGEMENT
Initiation 
• Inflammatory cysts – infection 
• Other cysts – 
-dental lamina 
-enamel organ 
-reduced enamel epithelium 
-cell rests of malassez
ENLARGEMENT 
1. ATTRACTION OF THE FLUID INTO THE CYST CAVITY 
2. THE RETENTION OF THE FLUID WITH IN THE CYST 
3. THE PRODUCTION OF RAISED INTERNAL HYDROSTSTIC 
PRESSURE 
4. THE RESORPTION OF THE SURROUNDING BONE WITH AN 
INCREASE IN THE SIZE OF THE BONE CAVITY
HARRIS 1974- 
THEORIES OF CYST 
EXPANSION 
1. MURAL GROWTH THEORY 
2. HYDROSTATIC ENLARGEMENT 
3. BONE RESORBING FACTOR
MURAL GROWTH 
PERIPHERAL CELL DIVISION 
ACCUMULATION OF CELLULAR CONTENT
HYDROSTATIC 
ENLARGEMENT 
SECRETION 
TRANSUDATION AND EXUDATION 
DIALYSIS
BONE RESORBING FACTOR 
OSTEOCLASTIC ACTIVITIES
DIAGNOSTIC FEATURES 
WATCH BEFORE THE CATCH 
• CLINICAL FINDINGS 
• Signs and symptoms of a jaw lesion depend 
on the dimension of the lesion. 
• Small cysts – Detected at an early stage as a 
corollary to routine radiographic 
examination. 
• Large cysts – Usually in case of a typical 
odontogenic cyst “expansion” of the labial or 
buccal aspect of the alveolar bone occurs.
Cont…… 
• Odontogenic cyst in the ramus or third 
molar region can cause Expansion of 
the lingual aspect alone. 
• Expansion of both the inner and outer 
bony margins is indicative of a lesion, 
other than a cyst.
EXPANSION 
• Growing cyst causes a locally discernible 
bulging of the External bony surface 
• Increase in size – Subperiosteal bone 
formation 
• Early stage – Smooth, hard, painless 
prominence 
• later expands to make the outer cortex thin 
with out micro fractures of the outer cortex 
• “ PING PONG BALL” CONSISTENCY
ELASTIC 
• The bone covering centre of the 
convexity becomes thinned and can be 
indented with pressure as the cyst 
growth proceeds 
• The term “ELASTIC” is used to 
describe this consistency 
• Micro Fracture Of The Outer Cortex 
Seen 
Egg shell crackling
INCIDENCE OF VARIOUS CYSTS IN 
DIFFERENT PARTS OF THE DENTAL 
ARCH 
• Periodontal cyst – Anywhere in the dental 
arch 
• Dentigerous cyst – Associated with impacted 
molars, displaced canines, premolars and third 
molars 
• Fissural cyst – Mostly Confined to the upper jaw 
& in the region of anatomical bony fusion
Cont…. 
• Solitary bone cyst – Present only in the 
mandible 
• Odontogenic Keratocyst – Lower third 
molar area and extending in to the ramus 
AND mandibular canine regions
OTHER CLINICAL FINDINGS… 
• Loosening of teeth 
• Involvement of neurovascular bundle 
• Presence of sinus tract
SYMPTOMS 
Small cysts – Asymptomatic 
Initial symptoms – Pain and swelling due to infection 
Large cysts – Pathological fracture in the weaker part jaw 
associated with pain and swelling. 
Edentulous – Displacement of denture 
Discoloration and loosening of tooth
INVESTIGATIONS 
To see through 
RADIOGRAPHIC 
EXAMINATION 
& 
ASPIRATION
RADIOGRAPHIC 
INVESTIGATIONS 
• Well defined round or oval area of radiolucency 
circumscribed by a sharp radiopaque margin 
• Radiographic variations possible depending on 
the type of the cyst, its location and the degree 
of bone destruction and expansion 
• Certain odontogenic and normal anatomic 
structures mimic radiolucencies suggestive of 
cyst formation
Dentigerous cyst
Odontogenic keratocyst
Dental cyst
Radicular cyst
ASPIRATION 
• Aspiration is done with a wide bore needle 
• Aspirated fluid – Straw colored fluid containing 
glary cholesterol crystals, provisional diagnosis 
would be a dental cyst 
• Keratin flakes (White cheesy material ) 
• Aspiration of air – Penetration in to the antrum 
• Failure to aspirate fluid or air – Solid lesion
THANK YOU

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1 intro to cyst, classification & pathophysiology

  • 1. Introduction To Cyst Classification & Dr V.RAMKUPaMthoApRhysiology CONSULTANT DENTAL &FACIOMAXILLARYSURGEON REG NO: 4118 TAMILNADU-INDIA( ASIA)
  • 2. Cyst KRAMER-1974 Definition : Cyst is defined as a pathological cavity having fluid, semi-fluid or gaseous contents that are not created by the accumulation of pus; frequently, but not always, is lined by an epithelium
  • 3. Killey & Kay -1966 • Cyst is an abnormal cavity in hard and soft tissues which contain fluid, semifluid, or gas and is often encapsulated and lined by epithelium.
  • 4. CLASSIFICATION OF CYSTS (W.H.O) • A. EPITHELIAL 1. Odontogenic a) Developmental: i ) Primordial cyst (Keratocyst) ii) Gingival cyst of infants iii) Gingival cyst of adult iv) Lateral periodontal cyst v) Dentigerous cyst (Follicular) vi) Eruption cyst vii) Calcifying odontogenic cyst
  • 5. b. Inflammatory: i) Radicular cyst ii) Residual cyst iii) Inflammatory collateral cyst iv) Paradental cyst 2. Non odontogenic Cysts: i) Nasopalatine duct cyst (incisive canal) ii) Median palatine, Median alveolar & Median mandibular cyst iii) Nasolabial cyst ( Nasoalveolar cyst) iv) Globulomaxillary cyst
  • 6. B. NON EPITHELIAL CYSTS 1. Simple bone cyst (Traumatic, Solitary, hemorrhagic bone cyst) 2. Aneurysmal bone cyst
  • 7. II) CYSTS ASSOCIATED WITH MAXILLARY ANTRUM • Benign mucosal cyst of maxillary antrum • Surgical ciliated cyst of maxilla.
  • 8. III) CYSTS OF THE SOFT TISSUES OF THE MOUTH, FACE & NECK 1) Dermoid and epidermoid cysts 2) Branchial cyst (Lympho epithelial) 3) Thyroglossal duct cyst 4) Anterior median lingual cyst 5) Oral cyst with gastric and intestinal epithelium 6) Cystic hygroma 7) Cysts of the salivary glands 8) Parasitic cysts: Hydatid cyst: Cysticercus Cellulosal
  • 9. DIAGRAM OF ODONTOGENIC CYSTS BASED ON CLINICAL AND RADIOGRAPHIC FEATURES
  • 10. CYST PATHOGENESIS INITIATION CYST FORMATION ENLARGEMENT
  • 11. Initiation • Inflammatory cysts – infection • Other cysts – -dental lamina -enamel organ -reduced enamel epithelium -cell rests of malassez
  • 12. ENLARGEMENT 1. ATTRACTION OF THE FLUID INTO THE CYST CAVITY 2. THE RETENTION OF THE FLUID WITH IN THE CYST 3. THE PRODUCTION OF RAISED INTERNAL HYDROSTSTIC PRESSURE 4. THE RESORPTION OF THE SURROUNDING BONE WITH AN INCREASE IN THE SIZE OF THE BONE CAVITY
  • 13. HARRIS 1974- THEORIES OF CYST EXPANSION 1. MURAL GROWTH THEORY 2. HYDROSTATIC ENLARGEMENT 3. BONE RESORBING FACTOR
  • 14. MURAL GROWTH PERIPHERAL CELL DIVISION ACCUMULATION OF CELLULAR CONTENT
  • 15. HYDROSTATIC ENLARGEMENT SECRETION TRANSUDATION AND EXUDATION DIALYSIS
  • 16. BONE RESORBING FACTOR OSTEOCLASTIC ACTIVITIES
  • 17. DIAGNOSTIC FEATURES WATCH BEFORE THE CATCH • CLINICAL FINDINGS • Signs and symptoms of a jaw lesion depend on the dimension of the lesion. • Small cysts – Detected at an early stage as a corollary to routine radiographic examination. • Large cysts – Usually in case of a typical odontogenic cyst “expansion” of the labial or buccal aspect of the alveolar bone occurs.
  • 18. Cont…… • Odontogenic cyst in the ramus or third molar region can cause Expansion of the lingual aspect alone. • Expansion of both the inner and outer bony margins is indicative of a lesion, other than a cyst.
  • 19. EXPANSION • Growing cyst causes a locally discernible bulging of the External bony surface • Increase in size – Subperiosteal bone formation • Early stage – Smooth, hard, painless prominence • later expands to make the outer cortex thin with out micro fractures of the outer cortex • “ PING PONG BALL” CONSISTENCY
  • 20. ELASTIC • The bone covering centre of the convexity becomes thinned and can be indented with pressure as the cyst growth proceeds • The term “ELASTIC” is used to describe this consistency • Micro Fracture Of The Outer Cortex Seen Egg shell crackling
  • 21. INCIDENCE OF VARIOUS CYSTS IN DIFFERENT PARTS OF THE DENTAL ARCH • Periodontal cyst – Anywhere in the dental arch • Dentigerous cyst – Associated with impacted molars, displaced canines, premolars and third molars • Fissural cyst – Mostly Confined to the upper jaw & in the region of anatomical bony fusion
  • 22. Cont…. • Solitary bone cyst – Present only in the mandible • Odontogenic Keratocyst – Lower third molar area and extending in to the ramus AND mandibular canine regions
  • 23. OTHER CLINICAL FINDINGS… • Loosening of teeth • Involvement of neurovascular bundle • Presence of sinus tract
  • 24. SYMPTOMS Small cysts – Asymptomatic Initial symptoms – Pain and swelling due to infection Large cysts – Pathological fracture in the weaker part jaw associated with pain and swelling. Edentulous – Displacement of denture Discoloration and loosening of tooth
  • 25. INVESTIGATIONS To see through RADIOGRAPHIC EXAMINATION & ASPIRATION
  • 26. RADIOGRAPHIC INVESTIGATIONS • Well defined round or oval area of radiolucency circumscribed by a sharp radiopaque margin • Radiographic variations possible depending on the type of the cyst, its location and the degree of bone destruction and expansion • Certain odontogenic and normal anatomic structures mimic radiolucencies suggestive of cyst formation
  • 27.
  • 28.
  • 29.
  • 30.
  • 35. ASPIRATION • Aspiration is done with a wide bore needle • Aspirated fluid – Straw colored fluid containing glary cholesterol crystals, provisional diagnosis would be a dental cyst • Keratin flakes (White cheesy material ) • Aspiration of air – Penetration in to the antrum • Failure to aspirate fluid or air – Solid lesion