This ppt discusses pharmacological actions, toxic effects and clinical applications of corticosteroids. It also mentions precations to be taken while using steroids
CBME (Competency Based Medical Education) curriculum is available for medical students
who were drowning in the sea of old information. Now the students will be able to inculcate
new competencies which include different skills, knowledge and attitude which a student
should possess while dealing with the patients keeping their behaviour within ethical
boundaries. The topics explained in the manual are given with relevant examples along with
the case scenarios wherever it is required for better grasping of the topic by the students.
The main aim of writing this book is to create awareness among the medical students about
the importance and requirement of ethical principles and moral conduct of a qualified
professional doctor while approaching the patient and also educate them about various aspects
of drug use, hands on training for administration of drugs, writing a rational prescription,
identifying & reporting adverse drug reactions also to motivate chronically ill patients to
adhere to the prescribed treatment. Sincere effort has been made to provide the relevant
content based on new competencies for the better and easy understanding of the medical
students.
New relevant competencies have been added to the second edition of the book. Colored graphs
to demonstrate the effects of drugs on BP have also been included. Students of MBBS
(Medicinae Baccalaureus Baccalaureus Chirurgiae) and other courses related to healthcare will
be benefitted through this book.
These slides contain the information about Estrogen, its basic pharmacology, its synthesis in human body, Functions of estrogen, role in female puberty, Agonists of estrogen and antagonists of estrogen, also contain detail of the receptors associated with the estrogen functioning.
This ppt discusses pharmacological actions, toxic effects and clinical applications of corticosteroids. It also mentions precations to be taken while using steroids
CBME (Competency Based Medical Education) curriculum is available for medical students
who were drowning in the sea of old information. Now the students will be able to inculcate
new competencies which include different skills, knowledge and attitude which a student
should possess while dealing with the patients keeping their behaviour within ethical
boundaries. The topics explained in the manual are given with relevant examples along with
the case scenarios wherever it is required for better grasping of the topic by the students.
The main aim of writing this book is to create awareness among the medical students about
the importance and requirement of ethical principles and moral conduct of a qualified
professional doctor while approaching the patient and also educate them about various aspects
of drug use, hands on training for administration of drugs, writing a rational prescription,
identifying & reporting adverse drug reactions also to motivate chronically ill patients to
adhere to the prescribed treatment. Sincere effort has been made to provide the relevant
content based on new competencies for the better and easy understanding of the medical
students.
New relevant competencies have been added to the second edition of the book. Colored graphs
to demonstrate the effects of drugs on BP have also been included. Students of MBBS
(Medicinae Baccalaureus Baccalaureus Chirurgiae) and other courses related to healthcare will
be benefitted through this book.
These slides contain the information about Estrogen, its basic pharmacology, its synthesis in human body, Functions of estrogen, role in female puberty, Agonists of estrogen and antagonists of estrogen, also contain detail of the receptors associated with the estrogen functioning.
after reading of physiological skills you will know how to do physiologic material according to medical ethics and laws and ensure the safety of patient and health care provider
good luck with that
Aabidullah rahimee
Pediatric IV cannulation is insertion of cannula into the vein for the purpose of administering medications / Infusion therapy / Transfusion of blood and its products /Nutrition to childrens
Dr. Somendra shukla is a one of the best Pediatrician & neonatologist in Gurgaon. He has vast expierence of 9 yrs in neonatology & pediatrics. He has cleared the prestigious Diplomate of National Board (DNB) and royal college of pediatrics, ondon (MRCPCH) examinations in pediatrics. He has worked and honed up her skills with some of the top corporates institutes of India such as Fortis hospital, moolchand medcity and paras hospital. He has also done his Fellowship in neonatology awarded by prestigious National neonatology forum of India.
He is a member of IAP and NNF and has attended various seminars and workshops and has presented several papers in various national conferences and conducted CMEs.
He is an expert in newborn intensive care including care of ventilated and extremely low birth weight babies (<1000g><750g). He has also been trained in cranial Ultrasonography and Echo studies in neonates.
Dr. Somendra shukla is a one of the best Pediatrician & neonatologist at Gurgaon.
He has vast expierence of 9 yrs in neonatology & pediatrics. He has cleared the prestigious Diplomate of National Board (DNB) and royal college of pediatrics, london (MRCPCH) examinations in pediatrics. He has worked and honed up her skills with some of the top corporates institutes of India such as Fortis hospital, moolchand medcity and paras hospital. He has also done his Fellowship in neonatology awarded by prestigious National neonatology forum of India.He is a member of IAP and NNF and has attended various seminars and workshops and has presented several papers in various national conferences and conducted CMEs. He is an expert in newborn intensive care including care of ventilated and extremely low birth weight babies (<1000g><750g). His area of interest are childhood vaccination, growth and development and childhood asthma.
IV Cannulation Introducing a single dose of concentrated medication directly...ssuser3155141
Introducing a single dose of concentrated medication directly into the systemic circulation
“Or”
The introduction of a large amount of fluid & electrolytes and other nutrients into the body via veins.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
DEMONSTRATION OF ADMINISTRATION OF DRUGS BY VARIOUS ROUTES IN MANNEQUINS (1).docx
1. DEMONSTRATION OF ADMINISTRATION OF DRUGS BY VARIOUS ROUTES IN
MANNEQUINS
Equipment tray: Syringe, gloves, alcohol/spirit swabs, cannula, labeled IV fluids, gauze piece,
adhesive, IV set, Emergency drugs, tourniquet, subcutaneous needle, etc.
IV Cannula and drip set:
SIZE COLOUR FLOW RATE USED IN:
26G PURPLE 13 ml/min Neonates
24G YELLOW 20 ml/min Neonates, Children
22G BLUE 36 ml/min Children
20G PINK 60 ml/min Females, Blood Transfusion
18G GREEN 90 ml/min Males, Trauma cases
16G GREY 180 ml/min Trauma cases
14G ORANGE 240 ml/min Trauma cases
INTRAVENOUS
Checklist:
1. Check the patient details
2. Communicate to the patient about what procedure you are going to do & take consent
3. Draw the bedside curtain
4. Check that all the necessary equipments are available
5. Perform hand hygiene and Wear gloves
6. Uncover the arm completely
2. 7. Ask the patient to relax and support his/her arm below the vein to be used
8. Apply tourniquet and look for a suitable vein
9. Clean the site using alcohol swab in firm circular motion and allow the site to dry
10. Pull the cap of the needle and keep it aside
11. Stabilize the vein by pulling the skin taut in the longitudinal direction of the vein using
non-dominant hand
12. Insert the needle at an angle of around 35 degrees
13. Puncture the skin and move the needle slightly into vein (3-5 mm)
14. Aspirate, if blood appears, hold the syringe steady
15. Loosen the tourniquet and inject slowly
16. If the blood doesn't appear, try again
17. Withdraw the needle swiftly and cover it with a cap, and discard the needle
18. Press a sterile gauge over the opening and secure it with an adhesive
19. Remove the gloves and perform hand hygiene
20. Evaluate the patient for any side effects
Sites: A good vein runs straight, stands up a little, fills and empties, and is easy to splint
Hand- Dorsal arch veins
Wrist- Volar aspect
Cubital fossa- Median antecubital, cephalic and basilic veins
Foot- Dorsal arch
Leg- Saphenous vein at the knee
Contraindications: Dialysis site, H/o mastectomy, fragile vein, H/o trauma, etc.
Examples: Bolus Injection IV Adenosine in PSVT, Slow Injection IV Calcium gluconate in
arrhythmias, Infusion of fluids- NS, RL, D5W, etc. Rapid infusion in shock.
Side effects and complications: Infiltration: pooling of fluid in tissue space due to misplaced
cannula, Hematoma- extravasation and collection of blood from severed vein, Thrombophlebitis,
Embolism (air)
3. INTRAMUSCULAR
Checklist:
1. Check the patient details
2. Communicate to the patient about what procedure you are going to do & take consent
3. Draw the bedside curtain
4. Check that all the necessary equipments are available
5. Perform hand hygiene and Wear gloves
6. Uncover the area to be injected
7. Clean the site using alcohol swab with firm circular motion
8. Allow the site to dry
9. Tell the patient to relax the muscle
10. Pull the cap from the needle
11. Insert the needle swiftly at an angle of 90 degrees
12. Aspirate briefly. If blood appears, withdraw the needle and replace it
13. If blood doesn't appear, inject slowly (0.5-2 min)
14. Withdraw the needle quickly
15. Carefully place the cap back on the needle
16. Discard the needle in the dustbin for sharp waste (White Puncture proof Container)
17. Apply a sterile gauge piece over the injection mark.
18. Press it, massage it and then apply the adhesive
19. Remove the gloves and perform hand hygiene
20. Evaluate the patient for any side effects
Sites:
- Deltoid- 3 finger-span below the Acromion process of Scapula
- Vastus lateralis- Anterolateral aspect of mid-thigh. Used in vaccination in toddlers.
4. - Dorsogluteal- upper outer quadrant of right buttock in prone position (Gluteus maximus)
- Ventrogluteal- Place the patient in side position, with the upper knee flexed. Put heel of
the palm on greater trochanter and Index finger on ASIS, with thumb pointing towards
groin and fingers pointing towards head end. The site of injection is in centre of
triangular gap in between index finger, middle finger and Iliac crest. (Gluteus medius and
minimus)
Contraindications: Gluteal muscle atrophy, Paraplegia, Quadriplegia, Marasmus, Ascending
Paralysis (GBS, Poliomyelitis), Overlying cellulitis, Coagulopathy
Examples: Antibiotics (Penicillin G, Benzathine penicillin, Streptomycin), Biologicals
(Immunoglobins, vaccines, and toxoids), Hormonal agents (Testosterone, medroxyprogesterone)
Side effects & Complications: Pain at site of injection, Abscess formation, Systemic reaction,
Nerve injury (eg. Sciatic in dorsogluteal) and Atrophy, Muscle injury and Contractures, Cellulitis
Z-track method: Technique for IM in which the doctor slightly pulls and holds pressure on the
skin when giving an injection, which leaves a zigzag path behind when they remove the needle
and release the skin. Z-track technique prevents staining of skin surface on IM Iron Injections.
5. SUBCUTANEOUS
Checklist:
1. Check the patient details
2. Communicate to the patient about what procedure you are going to do & take consent
3. Draw the bedside curtain
4. Check that all the necessary equipments are available
5. Perform hand hygiene and Wear gloves
6. Uncover the area to be injected (Abdomen)
7. Clean the site using alcohol swab with firm circular motion and allow the site to dry
8. Pull the cap from the needle
9. Using the non-dominant hand, pinch hold and pull taut the skin at the site of injection
(especially in thin patients)
10. Using the dominant hand, hold the syringe between thumb and forefinger
11. Insert needle in the base of the skin hold at an angle of 20-30 degree (normal syringe)
12. Relax the skin
13. Aspirate briefly. If blood appears, withdraw the needle and replace it. If blood doesn't
appear, inject slowly (0.5-2 min)
14. Withdraw the needle quickly
15. Carefully place the cap back on the needle
16. Discard the needle in the dustbin for sharp waste (White Puncture proof Container)
17. Apply a sterile gauge piece over the injection mark.
18. Press it, massage it and then apply the adhesive
19. Remove the gloves and perform hand hygiene
20. Evaluate the patient for any side effects
6. Sites: On abdomen- atleast 2 inches away from umbilicus, outer area of arm, upper back, upper
buttock, mid-thigh
Examples: Insulin, erythropoietin, IPV, Omalizumab (Anti IgE antibody., sumatriptan, LMWH
Side effects and complications- lipodystrophy, rash, pain, hematoma (LMWH action)
Insulin syringe for subcutaneous injection
INTRADERMAL: At an angle of 15 degrees. E.g. BCG vaccine, Tuberculin testing, fractional
fIPV, Triamcinolone injection on keloid
INTRA-ARTERIAL: E.g. thrombolysis in cases of embolism, vasodilator drugs in cases of
vasospasm
INTRA-ARTICULAR: Directly in joint. E.g. Hyaluronic acid in osteoarthritis, Steroids in
cases Rheumatoid arthritis
SUBLINGUAL: Nitroglycerin, Zolpidem, Ergotamine, Desmopressin, Apomorphine
TRANSDERMAL: Nicotine patch for smoking cessation, Estradiol to prevent menopausal
symptoms, Hyoscine for motion sickness, nitrate patches for angina
