Intrinsic Conduction System of the HeartIntrinsic Conduction Syste.pdfALANKARSTEELINDUSTRI
Intrinsic Conduction System of the Heart
Intrinsic Conduction System of the Heart A very important property of cardiac muscle is
automaticity, which is that cardiac muscle is capable of electrically stimulating itself in the
absence of neural information and does so in a rhythmic pattern Input from the autonomic
nervous system (sympathetic &. parasympathetic divisions) does NOT set the heart rhythm,
instead the ANS modifies the rhythm according to the body/s needs. The specialized cells found
in the sinoatrial node (SA node) usually regulate the cycling of the entire heart. This makes the
SA node the pacemaker of the heart. It dominates the rest of the heart because its cells depolarize
more rapidly that other cardiac muscle fibers and it causes them to depolarize based on its
rhythm. The wave of depolarization initiated by the SA node spreads across the heart utilizing
the gap junctions between the cardiac cells. After spreading across the atrial walls, the wave
stimulates the atrioventicular node (AV node) and is carried to the ventricles via the AV Bundle
(Bundle of His), bundle branches, and Purkinje fibers. These are the components of the heart's
conducting system. Identify the following components of the conducting system of the heart in
order of the direction of electrical activity. Electrical System of the Heart
Take Quiz direction of electrical activity. Electrical System of the Heart 1 [Choose] v[ Choose ]
Purkinje fibers Internodal pathways Left and right bundle branches Atrioventricular (AV) node
AV bundle AKA bundle of His Sinoatrial (SA) node.
Intrinsic Conduction System of the HeartIntrinsic Conduction Syste.pdfALANKARSTEELINDUSTRI
Intrinsic Conduction System of the Heart
Intrinsic Conduction System of the Heart A very important property of cardiac muscle is
automaticity, which is that cardiac muscle is capable of electrically stimulating itself in the
absence of neural information and does so in a rhythmic pattern Input from the autonomic
nervous system (sympathetic &. parasympathetic divisions) does NOT set the heart rhythm,
instead the ANS modifies the rhythm according to the body/s needs. The specialized cells found
in the sinoatrial node (SA node) usually regulate the cycling of the entire heart. This makes the
SA node the pacemaker of the heart. It dominates the rest of the heart because its cells depolarize
more rapidly that other cardiac muscle fibers and it causes them to depolarize based on its
rhythm. The wave of depolarization initiated by the SA node spreads across the heart utilizing
the gap junctions between the cardiac cells. After spreading across the atrial walls, the wave
stimulates the atrioventicular node (AV node) and is carried to the ventricles via the AV Bundle
(Bundle of His), bundle branches, and Purkinje fibers. These are the components of the heart's
conducting system. Identify the following components of the conducting system of the heart in
order of the direction of electrical activity. Electrical System of the Heart
Take Quiz direction of electrical activity. Electrical System of the Heart 1 [Choose] v[ Choose ]
Purkinje fibers Internodal pathways Left and right bundle branches Atrioventricular (AV) node
AV bundle AKA bundle of His Sinoatrial (SA) node.
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2. Functional histology of the
cardiac muscle
• The heart is composed of:
1- Cells full of contractile muscle proteins (e.g. ventricular muscle)
2- Cells with few contractile elements: (e.g. sinoatrial nodal "SAN")
• The cardiac muscle fibers:
• Similar to skeletal muscle in striated structure
• Similar to smooth muscle in being involuntary
Abo Ali
3. The intercalated
discs
• connect the ends of adjacent muscle
fibers at Z lines
• Functions:
• 1) Provide a strong union between
fibers to act as one unit
• 2) Contain gap junctions ~ electrical
continuity between cardiac cells
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4. •Properties of the cardiac muscle
1. Excitability
2. Rhythmicity
3. Contractility
4. conductivity
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9. Rhythmicity
• Defined as :
it is the ability of the heart to beat regularly & initiate its own regular
repetitive beats independent on nerve supply.
• Due to the presence of automatic cells in the heart:
• SAN Sinoatrial node (initiates cardiac impulses at a rate of 90- 105 I min .)
• 2 other automatic cells have the same property
• • AVN; Atrioventricular node (rate 40- 60 I min)
• • Purkinje fibers (rate 15-40 I min)
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11. • Nodal action potential
compared to ventricular action
potential:
• 1- Nodal A.P. has unstable membrane potential.
• 2- Nodal A.P. has spontaneous diastolic
depolarization.
• 3- Nodal A.P. has slower upstroke (absence of
fast Na current)
• 4- Nodal A.P. reaches peak at only +10 mV.
• 5- Nodal A.P. has no plateau.
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