This case report describes an 8-year-old boy who presented with cutaneous larva migrans (CLM), a skin infection caused by hookworm larvae, after traveling to Burkina Faso. The boy had a serpiginous rash on his foot. He was diagnosed with CLM based on his travel history and clinical presentation. He was treated successfully with oral ivermectin. CLM is a common infection in travelers to tropical regions who come into contact with contaminated soil. It presents as migrating skin lesions caused by hookworm larvae that are unable to fully develop in human skin. Early diagnosis and treatment can prevent complications.
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In recent years, syphilis has grown again with alarming numbers,
not only in Brazil, but worldwide. In October 2016, the Ministry
of Health recognized that the situation was getting out of hand and
declared an epidemic.
Most cases are in the Southeast region (56%), the most urbanized
and developed in the country. The disease that previously affected
the poorest population, today affects all social classes
Urticariform Lesions as a Manifestation of Secondary Syphilis: Case Reportsemualkaira
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IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
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IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
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was identified via polymerase chain reaction.
A Stowaway, Case Report of Subconjunctival Dirofilariosissemualkaira
We report the case of a 56-year-old man with subconjunctival ocular dirofilariasis caused by Dirofilaria repens. The treatment consisted in the surgical extraction of the parasite. The parasite species
was identified via polymerase chain reaction
Urticariform Lesions as a Manifestation of Secondary Syphilis: Case Reportsemualkaira
In recent years, syphilis has grown again with alarming numbers,
not only in Brazil, but worldwide. In October 2016, the Ministry
of Health recognized that the situation was getting out of hand and
declared an epidemic.
Most cases are in the Southeast region (56%), the most urbanized
and developed in the country. The disease that previously affected
the poorest population, today affects all social classes
Urticariform Lesions as a Manifestation of Secondary Syphilis: Case Reportsemualkaira
In recent years, syphilis has grown again with alarming numbers, not only in Brazil, but worldwide. In October 2016, the Ministry of Health recognized that the situation was getting out of hand and declared an epidemic.
"A Study of Clinical Profile of Leprosy in Post Leprosy Elimination Era"iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Ectoparasites on genitalia in this Era - a study at tertiary care center in T...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
A Stowaway, Case Report of Subconjunctival Dirofilariosissemualkaira
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was identified via polymerase chain reaction.
A Stowaway, Case Report of Subconjunctival Dirofilariosissemualkaira
We report the case of a 56-year-old man with subconjunctival ocular dirofilariasis caused by Dirofilaria repens. The treatment consisted in the surgical extraction of the parasite. The parasite species
was identified via polymerase chain reaction
A Stowaway, Case Report of Subconjunctival Dirofilariosissemualkaira
We report the case of a 56-year-old man with subconjunctival ocular dirofilariasis caused by Dirofilaria repens. The treatment consisted in the surgical extraction of the parasite. The parasite species
was identified via polymerase chain reaction.
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life-threatening infective gangrene, primarily seen in adults but
relatively rare in children. We present a nine-year-old male child
with spinal bifida and double incontence who was admitted at our
hospital due to gangrenous right hemi-scrotal ulcer extending to
the right thigh. It was proceeded with painful swollen hemi-scrotum 2wks prior to admission. We treated him aggressively with
broad spectrum antibiotics and early surgical debridement. Being
paraplegic with double incontinence hence spending most of the
time dressed with diapers we therefore think of poor hygiene and
the diaper rash as the etiological factors. Early surgical debridement with appropriate antibiotics and aggressive supportive care
usually gave good results.
Fournier’s Gangrene in a 9 Yrs. Old Patient; A Rare Presentation in Paediatri...semualkaira
Necrotizing fasciitis of the perineum and external genitalia is a
life-threatening infective gangrene, primarily seen in adults but
relatively rare in children. We present a nine-year-old male child
with spinal bifida and double incontence who was admitted at our
hospital due to gangrenous right hemi-scrotal ulcer extending to
the right thigh. It was proceeded with painful swollen hemi-scrotum 2wks prior to admission. We treated him aggressively with
broad spectrum antibiotics and early surgical debridement. Being
paraplegic with double incontinence hence spending most of the
time dressed with diapers we therefore think of poor hygiene and
the diaper rash as the etiological factors. Early surgical debridement with appropriate antibiotics and aggressive supportive care
usually gave good results.
Children's skin problems span nearly two decades from birth through adolescence. Several common pediatric skin conditions will be discussed including: diaper dermatitis, atopic dermatitis, warts, and acne.
follow me on my YouTube channel :- medic o mania
Trachoma History :-
Trachoma was previously known as Egyptian ophthalmia and endemic in the Middle East since prehistoric times.
Name comes from Greek word for ROUGH.
Other name :- Granular conjunctivitis, blinding trachoma, Egyptian ophthalmia
Trachoma is the most common infectious cause of blindness in the world Due to recurrent ocular infection with Chlamydia trachomatis.
Trachoma is the leading cause of preventable irreversible blindness in the world.
Repeat infection with this organism leads to conjunctival inflammation and scarring, trichiasis, and ultimately blinding corneal opacification
Epidemiology:-The World Health Organization (WHO) reports trachoma is endemic to more than 50 countries, with most blinding trachoma in Africa.
Worldwide, an estimated 2.2 million people are visually impaired as a result of trachoma, of whom 1.2 million are blind.
India has become free from Trachoma-with an overall prevalence found to be only 0.7% in the National Trachoma Survey Report (2014-17).
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the SARS-CoV-2).
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We report the case of a 56-year-old man with subconjunctival ocular dirofilariasis caused by Dirofilaria repens. The treatment consisted in the surgical extraction of the parasite. The parasite species
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with spinal bifida and double incontence who was admitted at our
hospital due to gangrenous right hemi-scrotal ulcer extending to
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broad spectrum antibiotics and early surgical debridement. Being
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usually gave good results.
Fournier’s Gangrene in a 9 Yrs. Old Patient; A Rare Presentation in Paediatri...semualkaira
Necrotizing fasciitis of the perineum and external genitalia is a
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with spinal bifida and double incontence who was admitted at our
hospital due to gangrenous right hemi-scrotal ulcer extending to
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Trachoma History :-
Trachoma was previously known as Egyptian ophthalmia and endemic in the Middle East since prehistoric times.
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Other name :- Granular conjunctivitis, blinding trachoma, Egyptian ophthalmia
Trachoma is the most common infectious cause of blindness in the world Due to recurrent ocular infection with Chlamydia trachomatis.
Trachoma is the leading cause of preventable irreversible blindness in the world.
Repeat infection with this organism leads to conjunctival inflammation and scarring, trichiasis, and ultimately blinding corneal opacification
Epidemiology:-The World Health Organization (WHO) reports trachoma is endemic to more than 50 countries, with most blinding trachoma in Africa.
Worldwide, an estimated 2.2 million people are visually impaired as a result of trachoma, of whom 1.2 million are blind.
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MBA (Virtual University of Pakistan)
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Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
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Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
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Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
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Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
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Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
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263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
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Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
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Cutaneous Larva Migrans: A Case Report in a Traveler Child
1. Annals of Clinical and Medical
Case Reports
Case Report
Cutaneous Larva Migrans: A Case Report in a Traveler Child
Decembrino L1, *
, Michetti G1
,Licardi G1
, Grecchi C2
, Pantaleo D1
, Grignani M1
, Colombo R4
, Capodieci C1
and Mazzucchelli I3
1
Department of Pediatrics and Neonatology, Civil Hospital Vigevano - ASST Pavia, Vigevano, Italy
2
Department of Infectious Diseases Unit, Fondazione IRCCS Policlinico San Matteo,Pavia, Italy
3
Department of Internal Medicine and Therapeutics, Rheumatology Unit, University of Pavia and Fondazione IRCCS Policlinico San
Matteo; Pavia, Italy
4
Service de Pedaitrie, Hopital du Jura, 2800-Deleèmont, Switzerland
Volume 3 Issue 3- 2020
Received Date: 16 Feb 2020
Accepted Date: 10 Mar 2020
Published Date: 16 Mar 2020
2. Key words
Child; Cutaneous larva migrans;
Diagnosis; Therapy; Epidemiology
1. Abstract
Cutaneous Larva Migrans (CLM) is the most common skin disease of tropical origincaused by
hookworms larvae, occurring in international travelers. Typical manifestations consist of er-
ythematous, serpiginous slightly elevated linear cutaneous lesions. We describe the case of an
8-year-old boy, with CLM infection acquired during travel to Burkina-Faso, and successfully
treated with Ivermectin. Epidemiology, clinicaldiagnosis and therapeutic are debated.
1.1. Background: Skin diseases are a common occurrence in international travellers and repre-
sent the third reason for seeking medical attention in returning travellers. As some skin diseases
can have life-threatening complications, especially in children, it is important to discriminate
whether the skin complaint represents a serious condition [1]. In these cases, history taking is
very important and must include specific destination of travel and all possible exposures to in-
sects and animals.
1.2. Case Presentation: An 8-year-old boy came to our pediatric Emergency Room because of
a skin lesion on the median left foot (Figure 1a, 1b). Physical examination showed an erythem-
atous, non-itching, slightly elevated both tortuous and linear lesion, extended for 3 cm. On the
foot plant, there were some round crusted lesions. The lesion was noted 5 days after the return
from travel to Burkina Faso. Traumas, insect bites or animal contacts were excluded. The boy
had a normal chest and abdominal physical examination, no fever, no lymph-adenomegaly, no
neurological signs. Apart from the foot lesion, the skin examination was unremarkable. Complete
blood count (CBC) showed marked eosinophilia (13.0% of WBC corresponding to 1296/L).
Treatment with an antihistamine agent was started and we referred the patient to the nearby
Tropical Infectious Disease Center for further assessments, where the diagnosis of Cutaneous
Larva Migrans (CML) was confirmed and he was prescribed oral ivermectin. A follow-up visit
was planned in the outpatient clinic of our center; after 15 days the boy showed complete remis-
sion (Figure 1c) and a decreased eosinophils count (8.1% of WBC corresponding to 740/ ) was
observed.
1. 3. Discussion: CLM is the most common skin disease of tropical origin caused by hookworms,
most commonly Ancylostoma vermemiense, Ancylostoma caninum, Necator Americanus, Unci-
naria stenocephala and Strongyloides stenocephala. It is endemic in the Caribbean, Central and
South America, Africa, Southeast Asia, and Australia. A temperature between 23°C and 30°C, the
presence of humid soil, and proper aeration favor larval growth. The degree of contamination and
the duration of contact with the soil also influence the occurrence of the disease. The adult worms
*Corresponding Author (s): Lidia Decembrino, Department of Pediatrics and Neonatology, Civil
Hospital Vigevano (PV) 27029, Italy, Tele: +39 3492121800, E-mail: lidia_decembrino@asst-pa-
via.it
http://www.acmcasereport.com/
Citation: Decembrino L, Cutaneous Larva Migrans: A Case Report in a Traveler Child. Annals of Clinical
and Medical Case Reports. 2020; 3(3): 1-3.
3. rare in children. It can occur when there is a heavy infestation of
larvae.Löffler’s syndrome is characterized by migratory pulmonary
infiltrates, peripheral eosinophilia, transient fever, cough and mal-
aise [10]. This association with CLM was first reported by Wright
and Gold in 1946. The exact pathogenesis remains unknown but
now type Ihypersensitivity reactionis the better hypothesis [10].
Even if complications associated to CLM aree primarily local, the
previously stated complications and intense pruritus may require
systemic treatments for a longer time.
Treatment depends on the localization and on the extent of in-
fection. Treatment by cryosurgery was routinely used prior to the
availability of anthelminthics such as albendazole, mebendazole,
thiabendazole and diethylcarbamazine [11]. The efficacy of liquid
nitrogen alone is limited as larvae can be far from the erythema,
while its combination with oral anti-helminths is more effective
than albendazole treatment alone. Ivermectin is the treatment
of choice, even if its safety has not been established in children
weighting less than 15 kg. A single oral dose (200 microgram/kg
body weight) is enough to kill the parasite effectively. When the
treatment fails, a second dose could be administered. Generally, a
single dose of ivermectin is more effective than albendazole (400
mg a day for 3 days). In case of Löffler’s syndrome Albendazole 10–
15 mg/kg/d for 3-5 days or longer seems to be the best treatment
approach [10]. An alternative treatment with 10% topical thiaben-
dazole ointment 4 times a day for at least 2 days is also reported in
children. German guidelines suggest to apply albendazole 10% in
a lipophilic base 3 times daily for 7-10 days in a large area as larvae
can be far from the visible lesion [10]. Topical albendazole can be
used in different concentrations (5 to 50%), and it is considered
safe in children. Ivermectin cream 1% seems to be an ineffective
treatment [11]. Antihistamine is used for the symptomatic treat-
ment of pruritus.
Recently, Del Giudice et al [12] reported 5 cases of autochthonous
CLM infection in France and they gave an overview of the autoch-
thonous cases in Europe, giving advertisement to view of CLM not
only as a typical and exclusive tropical diseases.
1. 4. Conclusions: In the era of modern medicine, it is important to
be aware of CLM infection that, even if rare, can easily be acquired
by international travelling children when playing on contaminated
ground. Prevention by wearing slippers and clothes is important to
avoid this infection along with policies for pets deworming. Even if
prognosis is good, early recognition and treatment help in prevent-
ing complication. The surveillance of CLM infection, imported or
autochthonous, can be helpful to monitor its incidence in Italy and
Europe.
Volume 3 Issue 3 -2020 Case Report
http://www.acmcasereport.com/ 3
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