This document provides steps to set up a HYSYS simulation of a crude oil distillation system including a crude oil preheat train, atmospheric crude tower, vacuum crude tower, and debutanizer. The key steps include defining components and property packages, inputting assay data for light, medium, and heavy crude oils, characterizing the components, blending the crudes, installing the blend as the feedstock, and setting up the initial crude oil feed and preheat operations. The overall goal is to simulate a crude distillation system to produce stabilized naphtha and other products from a mixed crude oil feed.