The document discusses various types of biomedical equipment classified into OT equipment, critical care equipment, diagnostic equipment, and treatment equipment. It provides examples for each type of equipment such as ventilators, multipara monitors, defibrillators, syringe pumps, infusion pumps, and ECG machines. It also describes some equipment in more detail including their purpose, main parameters, and how they function.
Mechanical ventilator, common modes, indications,nursing responsibilities MURUGESHHJ
it is an brief summary with diagrammatic presentation for NURSES regarding Mechanical ventilator, uses, complications, types, important terms,common modes, NIV, uses, NURING ROLES & RESPONSIBILITIES for handling INTUBATED patients...
Mechanical ventilator, common modes, indications,nursing responsibilities MURUGESHHJ
it is an brief summary with diagrammatic presentation for NURSES regarding Mechanical ventilator, uses, complications, types, important terms,common modes, NIV, uses, NURING ROLES & RESPONSIBILITIES for handling INTUBATED patients...
This slide include information regarding ventilators, modes of ventilators , its parts, weaning process, nursing care of patient in mechanical ventilation.
Arduino uno based obstructive sleep apnea detection using respiratory signaleSAT Journals
Abstract The monitoring of breathing dynamics is an essential diagnostic tool in various clinical environments, such as sleep analysis, intensive care and central nervous and physiological disorder analysis. This paper introduces a mathematical representation of respiratory pattern in frequency domain .Sleep apnea is defined as cessation of airflow to the lungs during sleep for 10 sec. It normally results from either lack in neural input from the central nervous system (Central Sleep Apnea) or Upper airway collapse (Obstructive sleep apnea).Microcontroller based sleep apnea monitor consists of a piezoelectric sensor attached to rib cage of patient. The amplified signal obtained from the patient is applied to the microcontroller. The method mentioned in the paper is based on extraction of four enhanced main energy features of respiratory signal from 30 second respiratory data through auto regressive modeling and other techniques. The four features extracted are Signal power, Respiration frequency, Dominant frequency in power spectrum, Maximum power in specturm . These features are compared with their threshold values and introduced to a series of condition for each epoch. Keywords: Auto-regression, Sleep apnea, Energy index, Respiratory frequency, Least squares method.
Measurement of Multiparameters using Anaesthesia Injector Based on Arm Processorijsrd.com
generally the patient should be anaesthetized while major operations are done. If the operations are performed for longer run, the anaesthesia cannot be given at a stretch. The amount of anaesthesia that is delivered to the patient is very important because the over dosage can threaten the life of the patient. If lower quantity is injected then at the time of surgical procedure patient may get conscious and they will feel the surgical pain. To overcome these problems, an automatic anaesthesia machine was designed using an ARM processor. This anaesthesia machine will be very much helpful in delivering the correct amount of anaesthesia in a particular period of time. In this method, a keypad is used for setting the amount of anaesthesia by the anaesthetist and it is delivered using a syringe pump. As soon as the value is entered, the microprocessor accesses the values and starts delivering the anaesthesia through the syringe pump by initiating the stepper motor. The stepper motor is used to drive the syringe pump. According to the stepper motor rotation the amount of anaesthesia will be administered to the patient and if anything goes wrong the alarm will turn on to indicate that there is some problem with the machine.
This slide include information regarding ventilators, modes of ventilators , its parts, weaning process, nursing care of patient in mechanical ventilation.
Arduino uno based obstructive sleep apnea detection using respiratory signaleSAT Journals
Abstract The monitoring of breathing dynamics is an essential diagnostic tool in various clinical environments, such as sleep analysis, intensive care and central nervous and physiological disorder analysis. This paper introduces a mathematical representation of respiratory pattern in frequency domain .Sleep apnea is defined as cessation of airflow to the lungs during sleep for 10 sec. It normally results from either lack in neural input from the central nervous system (Central Sleep Apnea) or Upper airway collapse (Obstructive sleep apnea).Microcontroller based sleep apnea monitor consists of a piezoelectric sensor attached to rib cage of patient. The amplified signal obtained from the patient is applied to the microcontroller. The method mentioned in the paper is based on extraction of four enhanced main energy features of respiratory signal from 30 second respiratory data through auto regressive modeling and other techniques. The four features extracted are Signal power, Respiration frequency, Dominant frequency in power spectrum, Maximum power in specturm . These features are compared with their threshold values and introduced to a series of condition for each epoch. Keywords: Auto-regression, Sleep apnea, Energy index, Respiratory frequency, Least squares method.
Measurement of Multiparameters using Anaesthesia Injector Based on Arm Processorijsrd.com
generally the patient should be anaesthetized while major operations are done. If the operations are performed for longer run, the anaesthesia cannot be given at a stretch. The amount of anaesthesia that is delivered to the patient is very important because the over dosage can threaten the life of the patient. If lower quantity is injected then at the time of surgical procedure patient may get conscious and they will feel the surgical pain. To overcome these problems, an automatic anaesthesia machine was designed using an ARM processor. This anaesthesia machine will be very much helpful in delivering the correct amount of anaesthesia in a particular period of time. In this method, a keypad is used for setting the amount of anaesthesia by the anaesthetist and it is delivered using a syringe pump. As soon as the value is entered, the microprocessor accesses the values and starts delivering the anaesthesia through the syringe pump by initiating the stepper motor. The stepper motor is used to drive the syringe pump. According to the stepper motor rotation the amount of anaesthesia will be administered to the patient and if anything goes wrong the alarm will turn on to indicate that there is some problem with the machine.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
7. RESPIRATION
What is Respiration?
Respiration is the process of supplying oxygen to and removing
carbon dioxide from the tissues.These gasses are carried in the
blood, oxygen from the lungs to the tissues and carbon dioxide from
the tissues to the lungs. The gas exchanges in the lungs are called
external respiration and those in the tissues are called internal
respiration. There is a very delicate balance between the absorption
and excretion of oxygen and carbon dioxide in the lungs and tissues,
and this balance is maintained by the respiratory or breathing activity.
If breathing stops for more than five minutes, death or permanent
damage will almost certainly occur. This may happen in many
conditions such as asphyxia, carbon monoxide poisoning, drowning
and electric shock, and artificial respiration is then essential.
8. Rsepiration
If a condition makes it very difficult for you to
breathe or get enough oxygen into your
blood.,this condition is called respiratory
failure.For reduced breathing or respiratory failure
(insufficiency), mechanical devices or respirators
are used in hospitals. These devices provide
artificial ventilation, supply enough oxygen and
eliminate the right amount of carbon dioxide,
maintain the desired arterial partial pressure of
carbon dioxide (PaCO2) and desired arterial
oxygen tension (PaO2)
9. VENTILATORS
Ventilator is basically device used to move breathable air in and out of the
lungs. It may be partial support or full support depending on the condition of the
patient. The basic parameters we are setting in a ventilator are 1)pressure -the
patient initiates every breath and the ventilator delivers support with the preset
pressure value,2) rate- the number of breaths required in 1 minute- normaly 12-
15 beats/min and 3) volume-(tidal Volume-TV) of air/o2 inhaled or exhaled in
one breath. In neonatal the minimum TV will be 2-20ml, in pediatrics it is 20ml-
300ml and in adults it will be upto 1000ml.
Volume is calculated as 7 ml/Kg and for a person with 60kg the volume
required is 420 Ml.
10.
11. Parameters of Ventilation
1)Pressure-Terminates with preset Pressure
2)Volume-Terminates with preset Tidal Volume
3)Flow-Termnates when inspiratory flow reaches a minimal
predetermined level
4)Time-Terminates when preset time has reached
12. VENTILATOR TERMS
Lung compliance- is the ability of the alveoli and lung tissue to expand on inspiration. The
lungs are passive, but they should stretch easily to ensure the sufficient intake of the air.
Airway Resistance: Airway resistance relates to the ease with which air flows through the
tubular respiratory structures. Higher resistances occur in smaller tubes such as the
bronchioles and alveoli that have not emptied properly.
Inspiratory Pause Time: When the pressure in the patient circuit and alveoli is equal,
there is aperiod of no flow. This period is called inspiratory pause time. Inspiratory Flow:
Inspiratory flow is represented as a positive flow above the zero line
Expiratory Flow: Expiratory flow is a negative flow below the zero line.
Tidal Volume: Tidal volume is the depth of breathing or the volume of gas inspired or
expired during each respiratory cycle.
Minute Volume: This refers to volume of gas exchanged per minute during quiet
breathing. Minute volume is obtained by multiplying the tidal volume by the breathing rate.
Respiration Rate: This is the number of breaths per second. It represents total respiratory
rate of the patient.
Inspiratory Expiratory Phase Time Ratio (I : E Ratio): This signifies the ratio of
inspiratory interval to expiratory interval of a mandatory breath. This ratio is normally
limited to 1:1.
Oxygen Percentage (F1O2): In all ventilatory modes, oxygen is delivered during the
inspiratory phase and the percentage (F1O2) is adjustable from 21 to 100%.
13. Positive End Expiratory Pressure (PEEP): PEEP is a therapist-selected pressure
level for the patient airway at the end of expiration in either mandatory or spontaneous
breathing.
Modes of Ventilation
Controller: A ventilator which operates independent of the patient’s inspiratory effort.
The inspiration is initiated by a mechanism which is controlled with respect to time,
pressure or another similar factor. Controlled ventilation is required for patients who
are unable to breath on their own.
Assistor: A ventilator which augments the inspiration of the patient by operating in
response to the patient’s inspiratory effort. A pressure sensor detects the slight
negative pressure that occurs each time the patient attempts to inhale and triggers the
process of inflating the lungs. Thus the ventilator helps the patient to inspire when
needed. A sensitivity adjustment provided on the equipment helps to select the
amount of effort required on the patient’s part to trigger the inspiration
process. The assist mode is required for those patients who are able to breathe but
are unable to inhale a sufficient amount of air or for whom breathing requires a great
deal of effort.
Assistor/Controller: A ventilator which combines both the controller and assistor
functions. In these devices, if the patient fails to breathe within a pre-determined time,
a timer automatically triggers the inspiration process to inflate the lungs. Therefore,
the breathing is controlled by the patient as long as it is possible, but in case the
patient should fail to do so, the machine is able to take over the function. Such
devices are most frequently used in critical care units
14.
15. ECMO
In extracorporeal membrane oxygenation
(ECMO), blood is pumped outside of your
body to a heart-lung machine that removes
carbon dioxide and sends oxygen-filled
blood back to tissues in the body. Blood
flows from the right side of the heart to the
membrane oxygenator in the heart-lung
machine, and then is rewarmed and sent
back to the body.
This method allows the blood to "bypass"
the
16. ECMO
heart and lungs, allowing these organs to rest and
heal. It may be used in care for heart muscle
diseases and inflamations,COVID-19, ARDS ,post
transplant complications etc.
17. The objective of patient monitoring is to have
a quantitative assessment of the important
physiological variables of the patients during
critical periods of their biological functions.
For diagnostic and research purposes, it is
necessary to know their actual value or trend
of change. Patient monitoring systems are
used for measuring continuously or at regular
intervals, automatically, the values of the
patient’s important physiological parameters
PATIENT MONITORING
18. MULTIPARA MONITORS
For knowing the vital signs of a patient like
Saturation of peripheral Oxygen (SPO2),
ECG,IBP& NIBP, Temp,EtCo2, etc
19. Patient monitors are also known as vital sign monitors as they are primarily
designed to measure and display vital physiological parameters. It basically consists
of the modular parts for measurement of the following:
• ECG and respiration measuring electronics
• Blood pressure (non-invasive
• Blood pressure (invasive)
• Temperature measuring electronics
• Pulse probe and SpO2 (pulse oximetry)
20. DEFIBRILATOR
Ventricular fibrillation is a serious cardiac emergency resulting from
asynchronous contraction of the heart muscles. This uncoordinated
movement of the ventricle walls of the heart may result from coronary
occlusion, from electric shock or from abnormalities of body chemistry.
Because of this irregular contraction of the muscle fibres, the
ventricles simply quiver rather than pumping the blood effectively. This
results in a steep fall of cardiac output and can prove fatal if adequate
steps are not taken promptly.
Ventricular fibrillation can be converted into a more efficient rhythm by
applying a high energy shock to the heart. This sudden surge across
the heart causes all muscle fibres to contract simultaneously.
Possibly, the fibres may then respond to normal physiological
pacemaking pulses. The instrument for administering the shock is
called a defibrillator
21. DEFIBRILATOR
Defibrillator is a device which gives an electric shock to the heart. This helps
reestablish normal contraction rhythms in a heart having dangerous arrhythmia
or in cardiac arrest. There is a 70% chance of survival within 3 minutes of
defibrillation after an arrest.
22.
23. SYRINGE PUMP & INFUSION
PUMP
SYRINGE PUMP IS USED TO INFUSE
MEDICATIONS TO A PATIENT FOR A
STIPULATED TIME.
INFUSION PUMP IS USED TO INFUSE
FLUIDS OR NUTRIENTS TO PATIENT FOR A
STIPULATED TIME
MAIN DIFFERENCE BETWEEN SYRINGE
PUMP AND INFUSION PUMP IS SYRINGE
PUMP IS USED FOR INFUSING SMALLER
VOLUMES IN SYRINGE FROM 10ML TO 50
ML WHILE INFUSION PUMP INFUSES
FLUIDS UPTO 2L
25. In syringe pumps a motor, through a gear-
reducing mechanism and a lead screw, applies
force to the plunger of a syringe containing the
drug. The device is mainly convenient for
applications that require the delivery of volumes
limited by the syringe size
26. In Infusion pump, we can either select rate or
Time .
If we need to deliver 100ml in 3 hr,we can set
33.3ml /min as the infusion rate(100/3)
If we need to deliver a volume 50 ml at a rate
5ml/hr,we can set time as 10 hr
27. ECG MACHINE
The procedure of recording the electrical
activity of the heart using electrodes placed
on the body is known as
Electrocardiography (ECG) and the
machine used to enable this is called an
ECG Machine. There are various types of
ECG machines which can be used
depending on the degree of realiability,
accuracy, portability, and comfort required. .
12 lead ECG Machine- It consists of three
28. standard limb leads, three augmented limb leads
and six precordial leads.
3 Lead ECG machine- This ECG machine
utilizes 4 electrodes for continuous monitoring.
Editor's Notes
Trigger selection: Trigger is the signal that the system uses to identify the beginning of the cardiac cycle.
The ECG is the preferred trigger mode and the R wave is the trigger event.
Timing: Timing refers to the positioning of inflation and deflation points on the arterial waveform. Inflation should occur at the onset of diastole and deflation should occur prior to ventricular ejection. With the pump in standby, the inflation marker identifies the selected period of balloon inflation based on the auto timing algorithm.
Waveform Characteristics:
• Assisted aortic end-diastolic pressure may be equal to the unassisted aortic end-diastolic pressure
• Rate of rise of assisted systole is prolonged
• Diastolic augmentation may appear widened
Physiologic Effects:
• Afterload reduction is essentially absent
• Increased MVO2 consumption due to the left ventricle ejecting against a greater resistance and a prolonged isovolumetric contraction phase
• IAB may impede left ventricular ejection and increase the afterload
Refractory Ventricular Failure
In the already compromised heart, a decrease in arterial pressure can result in a reduction in myocardial oxygen supply and a loss of functional myocardial tissue. To prevent worsening failure and cardiogenic shock, any signs of hemodynamic instability must be treated promptly. Treatment is aimed at relieving left ventricular workload and restoring the balance between myocardial oxygen supply and demand, allowing the myocardium time to heal and recover maximal function. Intra-aortic balloon counterpulsation assists in this effort by decreasing left ventricular workload and increasing coronary artery perfusion.
Cardiogenic Shock
Left ventricular (LV) failure following an acute myocardial infarction may progress to cardiogenic shock. As with LV failure, treatment is aimed at decreasing cardiac work, increasing myocardial oxygen supply, and decreasing myocardial oxygen demands. The combined effects of IABP therapy - increased oxygen supply, decreased afterload, and improved systemic perfusion - allows the heart to rest and halt the subsequent vicious cycle that often occurs with an acute myocardial infarction.
Unstable Refractory Angina
Myocardial ischemia and chest pain associated with unstable angina may be effectively treated with IABP therapy. The IAB can be beneficial in maintaining adequate coronary artery perfusion, relieving myocardial ischemia, and decreasing myocardial oxygen demand. If cardiac catheterization and further interventions are indicated, the patient can undergo these procedures in a more hemodynamically stable condition.
Impending Infarction
Patients experiencing severe chest pain accompanied by electrocardiogram changes and/or dysrhythmias, who do not obtain relief from drug therapy, are at great risk of developing a myocardial infarction. By improving coronary blood flow and reducing left ventricular work, chest pain and ECG changes associated with the myocardial ischemia can be minimized. If cardiac catheterization and further interventions are indicated, the patient can undergo these procedures in a more hemodynamically stable condition.
Mechanical Complications due to Acute Myocardial Infarction
Depending on the area of an acute myocardial infarction, mechanical complications can occur. Although these affect a small percentage of acute myocardial infarctions, the resulting hemodynamic compromise can have lethal consequences especially if not treated immediately. Ventricular septal defects, papillary muscle dysfunction or papillary muscle rupture usually require surgical intervention, often emergently. If the patient undergoes cardiac catheterization or surgical intervention in a hemodynamically compromised state, mortality and morbidity can be significantly increased. The IABP is utilized for temporary support to achieve hemodynamic stability until definitive measures are taken.
Ischemia Related Intractable Ventricular Arrhythmias
Ventricular irritability can be a frequent complication of acute MI, and may lead to severe dysrhythmias and further hemodynamic compromise. In most patients, conventional drug therapy and supportive measures are sufficient to reverse the irritability and dysrhythmias. However, patients refractory to conventional medical therapy are at high risk for further myocardial damage and death if this condition is not reversed. IABP therapy has proven effective in stabilizing the hemodynamic condition of these patients by increasing coronary artery perfusion, reducing ischemia and maintaining adequate peripheral perfusion.
Cardiac Support for High Risk General Surgical Patients and Coronary Angiography/Angioplasty Patients
Patients with existing impaired cardiac function are considered to be high-risk candidates for general surgery. Anesthetic agents and the procedure itself can place increased myocardial oxygen demands on the already impaired heart. Use of IABP provides hemodynamic stability by assisting in balancing myocardial oxygen supply and demand, preoperatively, intraoperatively, and during the critical post operative period when the demands on the heart are particularly high. Intra-aortic balloon counterpulsation may be used in conjunction with coronary angiography and angioplasty to support and stabilize high risk patients undergoing these procedures. Overall, intra-aortic balloon counterpulsation can provide increased coronary artery perfusion, and a decrease in cardiac work, thus reducing the risk of hemodynamic compromise due to reduced coronary flow during balloon inflation or acute coronary occlusion.
Septic Shock
Septic shock is caused by an overwhelming infection, affecting all the organ systems, increasing metabolic demands. It is characterized by low blood pressure, impaired neurologic function, decreased cardiac output, and high fever and can lead to cardiogenic shock. For patients unresponsive to maximal supportive therapy, intra-aortic balloon counterpulsation can increase coronary blood flow, reduce left ventricular work load by lowering systolic pressure, and improve tissue perfusion by maintaining adequate mean arterial pressure.
Weaning from Cardiopulmonary Bypass
Weaning a patient from cardiopulmonary bypass may be difficult in those cases in which aortic cross-clamping is prolonged, surgical revascularization is partially achieved, or pre-existing myocardial dysfunction is present. Termination of cardiopulmonary bypass may be marked by hypotension (low blood pressure) and a low cardiac index, despite administration of vasoactive drugs. The use of IABP in this setting decreases left ventricular resistance, increases cardiac output, and increases coronary artery and systemic perfusion pressures, facilitating the patient’s removal from cardiopulmonary bypass.
Support for Failed Angioplasty and Valvuloplasty
Intra-aortic balloon counterpulsation may be used to support and stabilize patients with severe left ventricular failure due to failed angioplasty. Overall, the IAB may provide increased coronary artery perfusion, and decrease cardiac work, thus reducing the risk of hemodynamic compromise due to reduced coronary flow or acute coronary occlusion. Unsuccessful valvuloplasty may result in cardiac dysfunction. The IABP may be used to support cardiac function in these patients until valve repair or replacement can be performed.
Intraoperative Pulsatile Flow Generation
In the past, the IABP has been used in conjunction with cardio-pulmonary bypass to generate pulsatile flow. Currently, the IABP is often used intraoperatively, but the primary objectives are not only pulsatile flow generation, but improving coronary artery perfusion, decreasing cardiac work (afterload) and reestablishing a balance between myocardial oxygen supply and myocardial oxygen demands.
Contraindications
Severe Aortic InsufficiencyIntra-aortic balloon counterpulsation is contraindicated in patients with severe aortic valve insufficiency. If an intra-aortic balloon was used, as the balloon inflated, blood in the aorta could be forced across the valve into the ventricle. Aortic regurgitation could possibly overloading the ventricle with additional blood volume and increase cardiac work.
Abdominal or Aortic AneurysmIf the patient has an abdominal or thoracic aortic aneurysm, the use of an intra-aortic balloon is contraindicated since the increased pressure generated with counterpulsation can worsen the aneurysm.
Severe Calcific Aorta-Iliac Disease or Peripheral Vascular Disease
Severe arterial calcific disease or peripheral vascular disease is a contraindication for IABP therapy although it is viewed by some as a relative contraindication. If the benefits of IABP therapy outweigh the risk of further compromised arterial blood flow, the clinician must decide if the use of the IABP is appropriate. Peripheral vascular disease may limit the physicians ability to advance the catheter through the atherosclerotic vessel.
Sheathless Insertion with Severe Obesity, Scarring of the GroinSheathless insertion is not recommended if the patient has a lot of fatty tissue, scar tissue at the site of the common femoral artery, or other contraindications to percutaneous insertion.
Prevention:
Limb Ischemia:
• Use smallest catheter/sheath sizes indicated.
• Risk factors: female,diabetics,peripheral vascular disease
• Select limb with best pulse
Excessive bleeding from insertion site:
• Careful insertion technique
• Monitor anticoagulation therapy
• Prevent catheter movement at insertion site
Thrombocytopenia:
• Avoid excessive heparin
Thrombosis:
• May occur during counterpulsation. The symptoms associated with thrombosis formation and treatment will depend on the organ system involved.
Immobility of balloon catheter:
• Maintain adequate trigger
• Observe movement of IAB status indicator
• If unable to inflate the IAB with the IABP, inflate and deflate the IAB by hand, using a syringe and stopcock once every 3-5 min.
Balloon leak:
• Do not remove the IAB from its tray until it is ready to be inserted
• Ensure proper balloon size used to patient size
• Ensure proper balloon placement
Infection:
• Sterile technique during insertion and dressing changes as per infection control policy
Aortic dissection:
• Insertion of IAB over guidewire with fluoroscopic control
Compartment syndrome: [may develop after balloon removal]
• Use the smallest catheter/sheath size indicated
• Maintain adequate colloid osmotic pressure